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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= wdS00004
         (783 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_O01382 Cluster: Caspase precursor (EC 3.4.22.-) (drICE)...   141   2e-32
UniRef50_UPI0000D55B5F Cluster: PREDICTED: similar to Caspase pr...   140   4e-32
UniRef50_UPI00015B4D75 Cluster: PREDICTED: similar to CG7788-PA;...   106   7e-22
UniRef50_UPI00015B57EE Cluster: PREDICTED: similar to ENSANGP000...   105   2e-21
UniRef50_Q98UI8 Cluster: Caspase-3; n=4; Chordata|Rep: Caspase-3...    95   1e-18
UniRef50_Q7Q1E0 Cluster: ENSANGP00000015118; n=2; Culicidae|Rep:...    91   4e-17
UniRef50_P55210 Cluster: Caspase-7 precursor (EC 3.4.22.60) (CAS...    87   5e-16
UniRef50_Q5DD62 Cluster: SJCHGC00800 protein; n=3; Schistosoma j...    83   1e-14
UniRef50_Q17FE3 Cluster: Caspase-1; n=3; Endopterygota|Rep: Casp...    81   3e-14
UniRef50_P55213 Cluster: Caspase-3 precursor (EC 3.4.22.56) (CAS...    81   3e-14
UniRef50_UPI0000E48555 Cluster: PREDICTED: similar to Lice2 cyst...    79   2e-13
UniRef50_Q7Q802 Cluster: ENSANGP00000021365; n=4; Cellia|Rep: EN...    76   1e-12
UniRef50_Q8I6Y2 Cluster: Caspase-3; n=2; Geodia cydonium|Rep: Ca...    49   3e-12
UniRef50_Q7Q803 Cluster: ENSANGP00000021367; n=6; Anopheles gamb...    75   3e-12
UniRef50_Q8JIS8 Cluster: Caspase 3A; n=3; Euteleostomi|Rep: Casp...    74   4e-12
UniRef50_A1L2P4 Cluster: LOC100036910 protein; n=1; Xenopus laev...    74   4e-12
UniRef50_UPI0000519DFF Cluster: PREDICTED: similar to Caspase pr...    73   8e-12
UniRef50_Q2TM51 Cluster: Caspase; n=3; Penaeidae|Rep: Caspase - ...    71   4e-11
UniRef50_UPI0000F2097E Cluster: PREDICTED: hypothetical protein;...    67   5e-10
UniRef50_Q92851-2 Cluster: Isoform B of Q92851 ; n=9; Mammalia|R...    65   2e-09
UniRef50_Q6KF63 Cluster: Caspase 10; n=3; Catarrhini|Rep: Caspas...    65   2e-09
UniRef50_Q92851 Cluster: Caspase-10 precursor (EC 3.4.22.63) (CA...    65   2e-09
UniRef50_Q3HL92 Cluster: Caspase-like protein; n=6; Eumetazoa|Re...    65   2e-09
UniRef50_Q7QKT2 Cluster: ENSANGP00000015505; n=3; Anopheles gamb...    64   3e-09
UniRef50_UPI0000E49D20 Cluster: PREDICTED: hypothetical protein;...    63   7e-09
UniRef50_Q4RG79 Cluster: Chromosome 2 SCAF15106, whole genome sh...    63   7e-09
UniRef50_A7SPA7 Cluster: Predicted protein; n=1; Nematostella ve...    63   9e-09
UniRef50_A7S4V9 Cluster: Predicted protein; n=2; Nematostella ve...    62   2e-08
UniRef50_Q14790 Cluster: Caspase-8 precursor (EC 3.4.22.61) (CAS...    61   4e-08
UniRef50_UPI00015553DC Cluster: PREDICTED: similar to caspase-15...    60   5e-08
UniRef50_Q9I8J3 Cluster: Caspase-8; n=11; Danio rerio|Rep: Caspa...    60   5e-08
UniRef50_UPI0000E48C15 Cluster: PREDICTED: similar to caspase 8;...    60   6e-08
UniRef50_Q0WYJ4 Cluster: Caspase 10; n=4; Percomorpha|Rep: Caspa...    60   8e-08
UniRef50_Q09HM6 Cluster: Caspase-8; n=1; Molgula tectiformis|Rep...    60   8e-08
UniRef50_A7SXL6 Cluster: Predicted protein; n=1; Nematostella ve...    59   1e-07
UniRef50_A7S119 Cluster: Predicted protein; n=1; Nematostella ve...    59   1e-07
UniRef50_Q9NHF9 Cluster: Caspase 6-like protein BG2; n=3; Sophop...    58   2e-07
UniRef50_A2BGE2 Cluster: Novel protein similar to caspase 8; n=4...    58   3e-07
UniRef50_UPI0000E472FD Cluster: PREDICTED: similar to caspase 8;...    57   6e-07
UniRef50_P55212 Cluster: Caspase-6 precursor (EC 3.4.22.59) (CAS...    56   1e-06
UniRef50_UPI0000ECB87F Cluster: Caspase-10 precursor (EC 3.4.22....    55   2e-06
UniRef50_Q5C0Y4 Cluster: SJCHGC07329 protein; n=1; Schistosoma j...    55   2e-06
UniRef50_Q16FR8 Cluster: Caspase-1; n=1; Aedes aegypti|Rep: Casp...    55   2e-06
UniRef50_UPI0000F2DFE7 Cluster: PREDICTED: similar to apoptotic ...    55   2e-06
UniRef50_A5JSK5 Cluster: Cysteine protease; n=2; Eukaryota|Rep: ...    55   2e-06
UniRef50_Q16PQ5 Cluster: Ecdysone-inducible caspase, putative; n...    55   2e-06
UniRef50_UPI0000586459 Cluster: PREDICTED: similar to caspase-3,...    54   3e-06
UniRef50_Q8I749 Cluster: Caspase-related protein; n=1; Suberites...    54   3e-06
UniRef50_A7S9L1 Cluster: Predicted protein; n=1; Nematostella ve...    54   3e-06
UniRef50_Q9IB64 Cluster: Caspase-8; n=1; Xenopus laevis|Rep: Cas...    54   4e-06
UniRef50_Q9IB62 Cluster: Caspase-10; n=5; Xenopus|Rep: Caspase-1...    54   5e-06
UniRef50_Q5D0W5 Cluster: Caspase 3C; n=2; Hydra vulgaris|Rep: Ca...    53   7e-06
UniRef50_UPI0001554FA5 Cluster: PREDICTED: similar to initiator ...    53   9e-06
UniRef50_Q2HZ04 Cluster: ICE-5; n=3; Bombyx mori|Rep: ICE-5 - Bo...    53   9e-06
UniRef50_UPI00015B57F0 Cluster: PREDICTED: similar to GA20532-PA...    52   1e-05
UniRef50_Q4JQQ0 Cluster: Initiator caspase; n=2; Gallus gallus|R...    52   1e-05
UniRef50_P31944 Cluster: Caspase-14 precursor (EC 3.4.22.-) (CAS...    52   1e-05
UniRef50_Q8ITP2 Cluster: AmphiCASP-6; n=2; Chordata|Rep: AmphiCA...    52   2e-05
UniRef50_Q6E5N8 Cluster: Caspase 8; n=1; Ictalurus punctatus|Rep...    52   2e-05
UniRef50_UPI00015B59A2 Cluster: PREDICTED: similar to ecdysone-i...    51   3e-05
UniRef50_Q4FJK5 Cluster: Casp9 protein; n=20; Eutheria|Rep: Casp...    51   3e-05
UniRef50_Q90WU0 Cluster: Caspase 9; n=2; Gallus gallus|Rep: Casp...    51   4e-05
UniRef50_Q4SC67 Cluster: Chromosome undetermined SCAF14659, whol...    51   4e-05
UniRef50_Q3T2L0 Cluster: Caspase-15; n=11; Theria|Rep: Caspase-1...    51   4e-05
UniRef50_A3QVU6 Cluster: Initiator caspase; n=3; Culicidae|Rep: ...    51   4e-05
UniRef50_UPI000065FEF6 Cluster: Homolog of Ictalurus punctatus "...    50   5e-05
UniRef50_Q28GK9 Cluster: Novel protein; n=1; Xenopus tropicalis|...    50   7e-05
UniRef50_Q0PKX0 Cluster: Caspase Xa; n=4; Danio rerio|Rep: Caspa...    49   1e-04
UniRef50_P55211 Cluster: Caspase-9 precursor (EC 3.4.22.62) (CAS...    49   1e-04
UniRef50_UPI0000E82482 Cluster: PREDICTED: hypothetical protein;...    48   2e-04
UniRef50_UPI0000F2DFE8 Cluster: PREDICTED: similar to initiator ...    48   3e-04
UniRef50_Q56VC9 Cluster: Caspase-8; n=3; Euteleostei|Rep: Caspas...    48   3e-04
UniRef50_Q4V923 Cluster: Zgc:101776 protein; n=8; Clupeocephala|...    47   5e-04
UniRef50_UPI0000F1EFFE Cluster: PREDICTED: hypothetical protein;...    47   6e-04
UniRef50_P42575 Cluster: Caspase-2 precursor (EC 3.4.22.55) (CAS...    46   0.001
UniRef50_UPI0000E4A098 Cluster: PREDICTED: similar to CGI-141 pr...    46   0.001
UniRef50_Q9Y1U6 Cluster: Cell death protein CED-3; n=1; Pristion...    46   0.001
UniRef50_UPI0000F1EBE3 Cluster: PREDICTED: similar to caspase 10...    45   0.002
UniRef50_Q9GV89 Cluster: Caspase 3A; n=1; Hydra vulgaris|Rep: Ca...    45   0.002
UniRef50_UPI00006A1E20 Cluster: Caspase-9 precursor (EC 3.4.22.6...    45   0.002
UniRef50_Q4SNC6 Cluster: Chromosome 8 SCAF14543, whole genome sh...    45   0.002
UniRef50_Q69HP8 Cluster: Caspase-1-like; n=1; Ciona intestinalis...    44   0.004
UniRef50_UPI0000F21D96 Cluster: PREDICTED: hypothetical protein,...    44   0.006
UniRef50_A2I5C3 Cluster: Putative caspase 3; n=1; Mytilus gallop...    44   0.006
UniRef50_Q4S1R8 Cluster: Chromosome undetermined SCAF14764, whol...    43   0.008
UniRef50_UPI0000F2CF2E Cluster: PREDICTED: similar to caspase 12...    42   0.017
UniRef50_UPI0000D56041 Cluster: PREDICTED: similar to CG7486-PB,...    42   0.017
UniRef50_UPI0000E45DDA Cluster: PREDICTED: similar to caspase 3;...    42   0.023
UniRef50_Q9I9L7 Cluster: Caspase; n=2; Danio rerio|Rep: Caspase ...    42   0.023
UniRef50_P55865 Cluster: Caspase-1-A precursor; n=3; Xenopus|Rep...    42   0.023
UniRef50_Q0Z8U7 Cluster: Caspase-8; n=1; Haemaphysalis longicorn...    41   0.030
UniRef50_P29466-2 Cluster: Isoform Beta of P29466 ; n=11; Theria...    40   0.053
UniRef50_P29466 Cluster: Caspase-1 precursor (EC 3.4.22.36) (CAS...    40   0.053
UniRef50_Q7ZXD2 Cluster: MGC53258 protein; n=3; Xenopus|Rep: MGC...    40   0.070
UniRef50_Q504J1 Cluster: Caspase b; n=7; Danio rerio|Rep: Caspas...    40   0.070
UniRef50_UPI0000E47913 Cluster: PREDICTED: similar to cysteine p...    40   0.093
UniRef50_UPI000155BC01 Cluster: PREDICTED: similar to cellular F...    39   0.12 
UniRef50_Q07BT4 Cluster: Caspase-1; n=2; Percomorpha|Rep: Caspas...    39   0.12 
UniRef50_UPI0000E47F37 Cluster: PREDICTED: similar to caspase-3,...    39   0.16 
UniRef50_Q178B7 Cluster: Caspase-3; n=2; Aedes aegypti|Rep: Casp...    39   0.16 
UniRef50_Q9XYF4 Cluster: Caspase Nc precursor (EC 3.4.22.-) (NED...    39   0.16 
UniRef50_Q0Z855 Cluster: Caspase-2; n=1; Haemaphysalis longicorn...    38   0.28 
UniRef50_A6NFM5 Cluster: Uncharacterized protein ENSP00000371619...    38   0.28 
UniRef50_P42573 Cluster: Cell death protein 3 precursor (EC 3.4....    38   0.37 
UniRef50_UPI0000661247 Cluster: Homolog of Brachydanio rerio "Ca...    37   0.50 
UniRef50_A3QU14 Cluster: DNA polymerase; n=1; Oryctes rhinoceros...    37   0.50 
UniRef50_UPI0000F2CF2D Cluster: PREDICTED: similar to evolutiona...    37   0.65 
UniRef50_UPI000065DDFC Cluster: CASP8 and FADD-like apoptosis re...    37   0.65 
UniRef50_Q498I3 Cluster: LOC780745 protein; n=6; Xenopus|Rep: LO...    37   0.65 
UniRef50_P51878 Cluster: Caspase-5 precursor (EC 3.4.22.58) (CAS...    36   0.86 
UniRef50_O15519-8 Cluster: Isoform 8 of O15519 ; n=3; Homo/Pan/G...    36   1.1  
UniRef50_O15519 Cluster: CASP8 and FADD-like apoptosis regulator...    36   1.1  
UniRef50_UPI000051A33A Cluster: PREDICTED: similar to CG6597-PA,...    36   1.5  
UniRef50_O42284 Cluster: Caspase-1; n=3; Gallus gallus|Rep: Casp...    35   2.0  
UniRef50_Q7KHK9 Cluster: DREAM; n=2; Sophophora|Rep: DREAM - Dro...    34   3.5  
UniRef50_P29466-4 Cluster: Isoform Delta of P29466 ; n=2; Euarch...    33   6.1  
UniRef50_Q74BT1 Cluster: Fibronectin type III domain protein; n=...    33   6.1  
UniRef50_Q9NBW3 Cluster: Cysteine protease; n=4; melanogaster su...    33   8.1  
UniRef50_Q8I5D6 Cluster: Putative uncharacterized protein; n=3; ...    33   8.1  

>UniRef50_O01382 Cluster: Caspase precursor (EC 3.4.22.-) (drICE)
           [Contains: Caspase subunit p21; Caspase subunit p12];
           n=13; Endopterygota|Rep: Caspase precursor (EC 3.4.22.-)
           (drICE) [Contains: Caspase subunit p21; Caspase subunit
           p12] - Drosophila melanogaster (Fruit fly)
          Length = 339

 Score =  141 bits (342), Expect = 2e-32
 Identities = 60/85 (70%), Positives = 72/85 (84%), Gaps = 2/85 (2%)
 Frame = +3

Query: 6   ETHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITL--SNTETDGXXXXXYR 179
           +T YK DN+W +FTA+ CP+LAGKPKLFFIQACQGD+LDGG+T+  S TETDG     Y+
Sbjct: 179 DTQYKLDNIWSFFTANHCPSLAGKPKLFFIQACQGDRLDGGVTMQRSQTETDGDSSMSYK 238

Query: 180 IPIHADFLIVFSTVPGYYSWRNTTR 254
           IP+HADFLI +STVPG+YSWRNTTR
Sbjct: 239 IPVHADFLIAYSTVPGFYSWRNTTR 263



 Score = 98.3 bits (234), Expect = 2e-19
 Identities = 45/60 (75%), Positives = 49/60 (81%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SWFMQSLC EL   G + DILTLLTFVCQRVA+DFES TPD   MHQQKQ+PCI +MLTR
Sbjct: 265 SWFMQSLCAELAANGKRLDILTLLTFVCQRVAVDFESCTPDTPEMHQQKQIPCITTMLTR 324


>UniRef50_UPI0000D55B5F Cluster: PREDICTED: similar to Caspase
           precursor (drICE); n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to Caspase precursor (drICE) -
           Tribolium castaneum
          Length = 309

 Score =  140 bits (339), Expect = 4e-32
 Identities = 61/84 (72%), Positives = 69/84 (82%), Gaps = 1/84 (1%)
 Frame = +3

Query: 6   ETHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDG-XXXXXYRI 182
           +T YKPD LW YF AD+CP+LAGKPK+FF+QACQGDKLDGG+ LS TETDG      YRI
Sbjct: 155 DTQYKPDLLWSYFAADRCPSLAGKPKIFFLQACQGDKLDGGVILSRTETDGHLEIDSYRI 214

Query: 183 PIHADFLIVFSTVPGYYSWRNTTR 254
           P  ADFL+V+STV GYYSWRNTTR
Sbjct: 215 PAQADFLVVYSTVKGYYSWRNTTR 238



 Score = 94.3 bits (224), Expect = 3e-18
 Identities = 42/60 (70%), Positives = 48/60 (80%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SWF+Q+LCEELRN G   D+ T+LTFV QRVA DFESN PD   MHQQKQ+PC+ SMLTR
Sbjct: 240 SWFIQALCEELRNKGFDYDLGTILTFVSQRVAFDFESNCPDSPTMHQQKQIPCVMSMLTR 299


>UniRef50_UPI00015B4D75 Cluster: PREDICTED: similar to CG7788-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           CG7788-PA - Nasonia vitripennis
          Length = 456

 Score =  106 bits (254), Expect = 7e-22
 Identities = 44/83 (53%), Positives = 58/83 (69%), Gaps = 2/83 (2%)
 Frame = +3

Query: 3   HETHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLS--NTETDGXXXXXY 176
           H+  Y  +++W  FT+  CP+L GKP+LFFIQAC+GD+ D GI L    +E DG     +
Sbjct: 303 HDRKYNAESIWSSFTSSNCPSLEGKPRLFFIQACRGDQTDEGIKLQYCRSEPDGHPNLVF 362

Query: 177 RIPIHADFLIVFSTVPGYYSWRN 245
           RIP H DFLI +ST+PG+YSWRN
Sbjct: 363 RIPTHRDFLIAYSTIPGFYSWRN 385



 Score = 87.4 bits (207), Expect = 4e-16
 Identities = 36/60 (60%), Positives = 49/60 (81%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SWF+Q+LC EL  YG ++D+LT+LTFVCQRVA+DFES +P+    HQ+KQ+P + +MLTR
Sbjct: 390 SWFVQALCSELDVYGDRQDLLTILTFVCQRVAIDFESYSPERANFHQKKQIPAVTTMLTR 449


>UniRef50_UPI00015B57EE Cluster: PREDICTED: similar to
           ENSANGP00000010319; n=2; Nasonia vitripennis|Rep:
           PREDICTED: similar to ENSANGP00000010319 - Nasonia
           vitripennis
          Length = 379

 Score =  105 bits (251), Expect = 2e-21
 Identities = 53/95 (55%), Positives = 63/95 (66%), Gaps = 7/95 (7%)
 Frame = +3

Query: 15  YKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITL---SNTETDGXXXXXYRIP 185
           YK +N+W  FTADKC +LAGKPKLFF QAC+GD LDGGI +     TETD      Y+IP
Sbjct: 229 YKLENVWKPFTADKCSSLAGKPKLFFFQACRGDNLDGGIKMMRSGTTETDS-SSASYQIP 287

Query: 186 IHADFLIVFSTVPGYYSWRN----TTRALGLCNLF 278
            +ADFL   STV G+YSWRN    T     LC++F
Sbjct: 288 TYADFLFAHSTVQGFYSWRNPEEGTWYVQSLCDVF 322



 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 24/61 (39%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPM-HQQKQVPCINSMLT 433
           +W++QSLC+    Y    D+  L+T   ++VA +F S   D+ PM H +KQVP + S L 
Sbjct: 312 TWYVQSLCDVFDEYAATHDLAKLMTITARKVATNFASYN-DLDPMLHGKKQVPSVISSLI 370

Query: 434 R 436
           R
Sbjct: 371 R 371


>UniRef50_Q98UI8 Cluster: Caspase-3; n=4; Chordata|Rep: Caspase-3 -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 282

 Score = 95.5 bits (227), Expect = 1e-18
 Identities = 46/101 (45%), Positives = 58/101 (57%), Gaps = 4/101 (3%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTV 221
           F  D+CP+L GKPKLFFIQAC+G +LD G+   +T+         RIP+ ADFL  +STV
Sbjct: 146 FRGDRCPSLVGKPKLFFIQACRGTELDPGVETDHTDHPDIPDGRERIPVEADFLYAYSTV 205

Query: 222 PGYYSWRNTTRA----LGLCNLFVKN*ETMVLKEIFLHS*H 332
           PGYYSWRNT         LC +  K    + L +I     H
Sbjct: 206 PGYYSWRNTMTGSWFIQSLCEMMTKYGSELELLQIMTRVNH 246



 Score = 65.3 bits (152), Expect = 2e-09
 Identities = 30/60 (50%), Positives = 44/60 (73%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SWF+QSLCE +  YG++ ++L ++T V  +VALDFES T ++     +KQ+PCI SMLT+
Sbjct: 218 SWFIQSLCEMMTKYGSELELLQIMTRVNHKVALDFES-TSNMPGFDAKKQIPCIVSMLTK 276


>UniRef50_Q7Q1E0 Cluster: ENSANGP00000015118; n=2; Culicidae|Rep:
           ENSANGP00000015118 - Anopheles gambiae str. PEST
          Length = 294

 Score = 90.6 bits (215), Expect = 4e-17
 Identities = 40/94 (42%), Positives = 60/94 (63%)
 Frame = +3

Query: 3   HETHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRI 182
           ++  Y+   +W +FTAD CP+LAG+PK+F +QAC+G++LD G+     + DG     Y I
Sbjct: 149 YDQPYELSLIWSFFTADNCPSLAGRPKIFVVQACRGNQLDHGV---KVQKDG--VARYSI 203

Query: 183 PIHADFLIVFSTVPGYYSWRNTTRALGLCNLFVK 284
           P HADFL  ++T+PG+ ++RNTT      N   K
Sbjct: 204 PTHADFLFAYATIPGFMAFRNTTEGSWFINELCK 237



 Score = 63.3 bits (147), Expect = 7e-09
 Identities = 31/60 (51%), Positives = 41/60 (68%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SWF+  LC+EL+  G + DI TLLTFV Q+VA D ES   ++   + +KQ PC+ SMLTR
Sbjct: 229 SWFINELCKELQENGHRYDINTLLTFVTQKVAYDHES-VSNMPEYNMRKQTPCVVSMLTR 287


>UniRef50_P55210 Cluster: Caspase-7 precursor (EC 3.4.22.60)
           (CASP-7) (ICE-like apoptotic protease 3) (ICE-LAP3)
           (Apoptotic protease Mch-3) (CMH-1) [Contains: Caspase-7
           subunit p20; Caspase-7 subunit p11]; n=58;
           Euteleostomi|Rep: Caspase-7 precursor (EC 3.4.22.60)
           (CASP-7) (ICE-like apoptotic protease 3) (ICE-LAP3)
           (Apoptotic protease Mch-3) (CMH-1) [Contains: Caspase-7
           subunit p20; Caspase-7 subunit p11] - Homo sapiens
           (Human)
          Length = 303

 Score = 87.0 bits (206), Expect = 5e-16
 Identities = 41/77 (53%), Positives = 50/77 (64%), Gaps = 1/77 (1%)
 Frame = +3

Query: 27  NLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITL-SNTETDGXXXXXYRIPIHADFL 203
           +L  +F  D+C TL  KPKLFFIQAC+G +LD GI   S    D      Y+IP+ ADFL
Sbjct: 161 DLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFL 220

Query: 204 IVFSTVPGYYSWRNTTR 254
             +STVPGYYSWR+  R
Sbjct: 221 FAYSTVPGYYSWRSPGR 237



 Score = 60.5 bits (140), Expect = 5e-08
 Identities = 28/60 (46%), Positives = 40/60 (66%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SWF+Q+LC  L  +G   +I+ +LT V  RVA  FES + D    H++KQ+PC+ SMLT+
Sbjct: 239 SWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDD-PHFHEKKQIPCVVSMLTK 297


>UniRef50_Q5DD62 Cluster: SJCHGC00800 protein; n=3; Schistosoma
           japonicum|Rep: SJCHGC00800 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 288

 Score = 82.6 bits (195), Expect = 1e-14
 Identities = 33/72 (45%), Positives = 49/72 (68%)
 Frame = +3

Query: 39  YFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFLIVFST 218
           +F  D+CP+L GKPKLFF QAC+G   D G++    +  G      ++P+ AD L+ +ST
Sbjct: 143 FFRGDRCPSLIGKPKLFFFQACRGVSFDKGVSTMVADA-GDDVIVRKLPVEADILVSYST 201

Query: 219 VPGYYSWRNTTR 254
           VPGY++WRN+T+
Sbjct: 202 VPGYFAWRNSTK 213



 Score = 39.5 bits (88), Expect = 0.093
 Identities = 24/63 (38%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
 Frame = +2

Query: 257 SWFMQSLCEELRN---YGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSM 427
           SW++Q LC  L      G   DI+TLLT V + VA  + S+T  +      KQ+    S 
Sbjct: 215 SWYIQELCNALETDIKNGNHTDIMTLLTVVARVVAYQYRSSTRQV-ETDNMKQMTSTFST 273

Query: 428 LTR 436
           LTR
Sbjct: 274 LTR 276


>UniRef50_Q17FE3 Cluster: Caspase-1; n=3; Endopterygota|Rep:
           Caspase-1 - Aedes aegypti (Yellowfever mosquito)
          Length = 293

 Score = 81.0 bits (191), Expect = 3e-14
 Identities = 36/85 (42%), Positives = 50/85 (58%), Gaps = 5/85 (5%)
 Frame = +3

Query: 6   ETHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLS-----NTETDGXXXX 170
           +  Y  D+LW  F  + CP+L GKPK+FFIQAC+G++ D G+  +     +         
Sbjct: 128 DNKYNVDSLWKNFVGNACPSLIGKPKMFFIQACRGEQFDEGVAYAAKSPKDMVDSRQEQV 187

Query: 171 XYRIPIHADFLIVFSTVPGYYSWRN 245
            Y IP  AD L+++ST  GYYSWRN
Sbjct: 188 LYSIPAMADLLVMYSTYDGYYSWRN 212



 Score = 68.9 bits (161), Expect = 1e-10
 Identities = 33/60 (55%), Positives = 40/60 (66%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SWF+QSLC EL   G  RD+LTLLT V +R A +F+S  P    M   KQ+PCI SMLT+
Sbjct: 217 SWFIQSLCTELDENGRVRDLLTLLTGVSRRTAYEFQSFVPHNAKMDAMKQIPCIVSMLTK 276


>UniRef50_P55213 Cluster: Caspase-3 precursor (EC 3.4.22.56)
           (CASP-3) (Apopain) (Cysteine protease CPP32) (Yama
           protein) (CPP-32) (SREBP cleavage activity 1) (SCA-1)
           (LICE) (IRP) [Contains: Caspase-3 subunit p17; Caspase-3
           subunit p12]; n=32; Euteleostomi|Rep: Caspase-3
           precursor (EC 3.4.22.56) (CASP-3) (Apopain) (Cysteine
           protease CPP32) (Yama protein) (CPP-32) (SREBP cleavage
           activity 1) (SCA-1) (LICE) (IRP) [Contains: Caspase-3
           subunit p17; Caspase-3 subunit p12] - Rattus norvegicus
           (Rat)
          Length = 277

 Score = 81.0 bits (191), Expect = 3e-14
 Identities = 39/71 (54%), Positives = 48/71 (67%), Gaps = 1/71 (1%)
 Frame = +3

Query: 39  YFTADKCPTLAGKPKLFFIQACQGDKLDGGI-TLSNTETDGXXXXXYRIPIHADFLIVFS 215
           +F  D C +L GKPKLF IQAC+G +LD GI T S T+ D       +IP+ ADFL  +S
Sbjct: 142 FFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGTDDD---MACQKIPVEADFLYAYS 198

Query: 216 TVPGYYSWRNT 248
           T PGYYSWRN+
Sbjct: 199 TAPGYYSWRNS 209



 Score = 59.7 bits (138), Expect = 8e-08
 Identities = 29/60 (48%), Positives = 42/60 (70%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SWF+QSLC  L+ Y  + + + +LT V ++VA +FES + D T  H +KQ+PCI SMLT+
Sbjct: 213 SWFIQSLCAMLKLYAHKLEFMHILTRVNRKVATEFESFSLDAT-FHAKKQIPCIVSMLTK 271


>UniRef50_UPI0000E48555 Cluster: PREDICTED: similar to Lice2
           cysteine protease, partial; n=2; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to Lice2 cysteine
           protease, partial - Strongylocentrotus purpuratus
          Length = 388

 Score = 78.6 bits (185), Expect = 2e-13
 Identities = 36/69 (52%), Positives = 45/69 (65%), Gaps = 6/69 (8%)
 Frame = +3

Query: 57  CPTLAGKPKLFFIQACQGDKLDGGITLSNTETDG------XXXXXYRIPIHADFLIVFST 218
           CPTL GKPKLFFIQAC+G ++D G+ +   E D            Y IP+ ADFL+ FS+
Sbjct: 249 CPTLVGKPKLFFIQACRGTQMDHGVRVPAGEGDDEPDAALGQKMFYTIPVEADFLMAFSS 308

Query: 219 VPGYYSWRN 245
            PGYYSWR+
Sbjct: 309 TPGYYSWRS 317



 Score = 41.5 bits (93), Expect = 0.023
 Identities = 22/60 (36%), Positives = 35/60 (58%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SWF+Q++      YGT  D+  ++T V + VA  +ES + D    + +KQ+PC  S LT+
Sbjct: 322 SWFIQAIITIFEKYGTCMDVNQMMTRVNRAVAYRYESISGD-ERYNGRKQMPCFVSTLTK 380


>UniRef50_Q7Q802 Cluster: ENSANGP00000021365; n=4; Cellia|Rep:
           ENSANGP00000021365 - Anopheles gambiae str. PEST
          Length = 296

 Score = 75.8 bits (178), Expect = 1e-12
 Identities = 34/79 (43%), Positives = 47/79 (59%), Gaps = 2/79 (2%)
 Frame = +3

Query: 15  YKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLS--NTETDGXXXXXYRIPI 188
           Y  D LW  F  + C TL GKPKLFF+QAC+G   D G+ L   + ++D      Y IP 
Sbjct: 144 YSVDKLWESFMGNACTTLLGKPKLFFVQACRGSTFDKGVKLGCRDLDSDHFSSHKYVIPT 203

Query: 189 HADFLIVFSTVPGYYSWRN 245
            AD L+++S+  G+ SWR+
Sbjct: 204 TADLLVMYSSYKGHVSWRS 222



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 29/60 (48%), Positives = 38/60 (63%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SWF+Q+LC EL       ++L LLT V +RVA D++SN P    M   KQ+P I SMLT+
Sbjct: 227 SWFIQALCVELETNWKHMELLQLLTGVSRRVAYDYQSNEPSKGRMDAMKQMPSIVSMLTK 286


>UniRef50_Q8I6Y2 Cluster: Caspase-3; n=2; Geodia cydonium|Rep:
           Caspase-3 - Geodia cydonium (Sponge)
          Length = 426

 Score = 48.8 bits (111), Expect(2) = 3e-12
 Identities = 23/62 (37%), Positives = 31/62 (50%)
 Frame = +3

Query: 135 LSNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTRALGLCNLFVKN*ETMVLKEI 314
           L   ETDG       +P  ADF++ ++TVPGY SWRN+         FV     +  KE 
Sbjct: 317 LDADETDGGGYSREALPTEADFVLAYATVPGYVSWRNSEYGSWFIKAFVDTMRDLASKEH 376

Query: 315 FL 320
           F+
Sbjct: 377 FM 378



 Score = 46.0 bits (104), Expect(2) = 3e-12
 Identities = 19/45 (42%), Positives = 29/45 (64%)
 Frame = +3

Query: 24  DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDG 158
           ++L  YF     P+L GKPK+F +QAC+G K D G+   +T+ +G
Sbjct: 249 EDLTKYFDGVNRPSLIGKPKVFVVQACRGGKFDYGVESESTDGEG 293



 Score = 36.3 bits (80), Expect = 0.86
 Identities = 19/60 (31%), Positives = 35/60 (58%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SWF+++  + +R+  ++   + +LT V ++VA DF+S         + KQ+P   +MLTR
Sbjct: 358 SWFIKAFVDTMRDLASKEHFMDILTEVNRKVAYDFQSR-------GRNKQIPAPVTMLTR 410


>UniRef50_Q7Q803 Cluster: ENSANGP00000021367; n=6; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000021367 - Anopheles gambiae
           str. PEST
          Length = 320

 Score = 74.5 bits (175), Expect = 3e-12
 Identities = 32/60 (53%), Positives = 47/60 (78%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SWF+++LC+ELR +G  +++L LLT V +RVA +F+SN P+ + +  QKQ+PCI SMLTR
Sbjct: 254 SWFIRALCDELREHGNSKELLQLLTSVSRRVAYEFQSNVPNNSQIDCQKQMPCIVSMLTR 313



 Score = 66.9 bits (156), Expect = 5e-10
 Identities = 38/99 (38%), Positives = 46/99 (46%), Gaps = 22/99 (22%)
 Frame = +3

Query: 15  YKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETD------------- 155
           +  D LW  F  D CP+L GKPKLFFIQAC+G   D G+  S   T              
Sbjct: 151 FNVDRLWENFIGDSCPSLLGKPKLFFIQACRGSSFDTGVHFSQCMTQVAKTVVPYAMREL 210

Query: 156 ---------GXXXXXYRIPIHADFLIVFSTVPGYYSWRN 245
                          Y IP  AD L+++ST  G+YSWRN
Sbjct: 211 PQPSIVPGCPKSSIQYAIPSMADLLVMYSTYKGHYSWRN 249


>UniRef50_Q8JIS8 Cluster: Caspase 3A; n=3; Euteleostomi|Rep: Caspase
           3A - Oryzias latipes (Medaka fish) (Japanese ricefish)
          Length = 290

 Score = 74.1 bits (174), Expect = 4e-12
 Identities = 42/96 (43%), Positives = 52/96 (54%), Gaps = 4/96 (4%)
 Frame = +3

Query: 57  CPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTVPGYYS 236
           C +L GKPKLFFIQAC+G   D GI     E D       +IP+ ADFL  +STV GYYS
Sbjct: 161 CLSLVGKPKLFFIQACRGMLFDEGI-----EHDAKDDTSEKIPLEADFLFAYSTVSGYYS 215

Query: 237 WRNTTRA----LGLCNLFVKN*ETMVLKEIFLHS*H 332
           WR+T         LC +  K  +T+ L +I     H
Sbjct: 216 WRSTANGSWFIQSLCEMLEKFSKTLDLMQIMTRVNH 251



 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 26/60 (43%), Positives = 39/60 (65%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SWF+QSLCE L  +    D++ ++T V  +VA  FES++ +      +KQ+PCI SMLT+
Sbjct: 223 SWFIQSLCEMLEKFSKTLDLMQIMTRVNHKVATHFESSS-NAPGFSGKKQIPCIVSMLTK 281


>UniRef50_A1L2P4 Cluster: LOC100036910 protein; n=1; Xenopus
           laevis|Rep: LOC100036910 protein - Xenopus laevis
           (African clawed frog)
          Length = 235

 Score = 74.1 bits (174), Expect = 4e-12
 Identities = 35/67 (52%), Positives = 43/67 (64%)
 Frame = +3

Query: 27  NLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFLI 206
           NL   F  D+C TL GKPK+FFIQAC+G +LD GI   +    G     +RIP+ ADFL 
Sbjct: 149 NLTDLFRGDRCKTLVGKPKIFFIQACRGTELDSGIETDSGSEPG--EETHRIPVEADFLY 206

Query: 207 VFSTVPG 227
            +STVPG
Sbjct: 207 AYSTVPG 213


>UniRef50_UPI0000519DFF Cluster: PREDICTED: similar to Caspase
           precursor (drICE); n=1; Apis mellifera|Rep: PREDICTED:
           similar to Caspase precursor (drICE) - Apis mellifera
          Length = 280

 Score = 72.9 bits (171), Expect = 8e-12
 Identities = 37/85 (43%), Positives = 52/85 (61%), Gaps = 1/85 (1%)
 Frame = +3

Query: 3   HETHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGIT-LSNTETDGXXXXXYR 179
           ++  Y    +W  F +D C +LAGKPKLFFIQAC+G   D GI   S  ++D      Y 
Sbjct: 129 YDISYPVQMIWQPFNSDNCISLAGKPKLFFIQACRGVTSDSGIQGRSGIDSD---EMTYV 185

Query: 180 IPIHADFLIVFSTVPGYYSWRNTTR 254
           +P+ ADFL  +ST+ G YS+R+T +
Sbjct: 186 LPMTADFLYAYSTMEGCYSFRDTNK 210



 Score = 44.4 bits (100), Expect = 0.003
 Identities = 21/63 (33%), Positives = 37/63 (58%)
 Frame = +2

Query: 248 NSCSWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSM 427
           N  SW++Q+LC+ +  +    D+L +LT   ++VA ++ S+  D     ++KQ+P   S 
Sbjct: 209 NKGSWYIQTLCKVINEHWKNYDMLKMLTITLRKVATEY-SSQHDEMDKDKKKQMPTFTST 267

Query: 428 LTR 436
           LTR
Sbjct: 268 LTR 270


>UniRef50_Q2TM51 Cluster: Caspase; n=3; Penaeidae|Rep: Caspase -
           Fenneropenaeus merguiensis (Banana prawn) (Penaeus
           merguiensis)
          Length = 320

 Score = 70.5 bits (165), Expect = 4e-11
 Identities = 33/84 (39%), Positives = 54/84 (64%), Gaps = 7/84 (8%)
 Frame = +3

Query: 30  LWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSN------TETDG-XXXXXYRIPI 188
           LW  FTA++C +LAGKPKL+FIQAC+G  +D G+ +S        +TD       Y IP+
Sbjct: 168 LWINFTAERCASLAGKPKLYFIQACRGLDVDKGVNMSRAVRGMAVQTDNIGSTEEYVIPV 227

Query: 189 HADFLIVFSTVPGYYSWRNTTRAL 260
           HAD L+++++ PG+ ++ +  + +
Sbjct: 228 HADQLVMWASYPGFPAFTSNRKGI 251


>UniRef50_UPI0000F2097E Cluster: PREDICTED: hypothetical protein;
           n=3; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 266

 Score = 66.9 bits (156), Expect = 5e-10
 Identities = 29/67 (43%), Positives = 41/67 (61%)
 Frame = +3

Query: 45  TADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTVP 224
           T+D CP+L  KPK+FF+QAC+G + D G+   + E          +P   DFL  +STV 
Sbjct: 127 TSDLCPSLRDKPKIFFLQACRGVEYDPGVEADSVEASEDFFGISDVP-ELDFLCCYSTVE 185

Query: 225 GYYSWRN 245
           GY++WRN
Sbjct: 186 GYFAWRN 192


>UniRef50_Q92851-2 Cluster: Isoform B of Q92851 ; n=9; Mammalia|Rep:
           Isoform B of Q92851 - Homo sapiens (Human)
          Length = 479

 Score = 65.3 bits (152), Expect = 2e-09
 Identities = 34/73 (46%), Positives = 46/73 (63%), Gaps = 4/73 (5%)
 Frame = +3

Query: 39  YFTADKCPTLAGKPKLFFIQACQGDKLDGGITLS----NTETDGXXXXXYRIPIHADFLI 206
           +FTA +CP LA KPKLFFIQACQG+++   +++     N E          IP  ADFL+
Sbjct: 337 HFTALQCPRLAEKPKLFFIQACQGEEIQPSVSIEADALNPE-QAPTSLQDSIPAEADFLL 395

Query: 207 VFSTVPGYYSWRN 245
             +TVPGY S+R+
Sbjct: 396 GLATVPGYVSFRH 408


>UniRef50_Q6KF63 Cluster: Caspase 10; n=3; Catarrhini|Rep: Caspase
           10 - Homo sapiens (Human)
          Length = 455

 Score = 65.3 bits (152), Expect = 2e-09
 Identities = 34/73 (46%), Positives = 46/73 (63%), Gaps = 4/73 (5%)
 Frame = +3

Query: 39  YFTADKCPTLAGKPKLFFIQACQGDKLDGGITLS----NTETDGXXXXXYRIPIHADFLI 206
           +FTA +CP LA KPKLFFIQACQG+++   +++     N E          IP  ADFL+
Sbjct: 313 HFTALQCPRLAEKPKLFFIQACQGEEIQPSVSIEADALNPE-QAPTSLQDSIPAEADFLL 371

Query: 207 VFSTVPGYYSWRN 245
             +TVPGY S+R+
Sbjct: 372 GLATVPGYVSFRH 384


>UniRef50_Q92851 Cluster: Caspase-10 precursor (EC 3.4.22.63)
           (CASP-10) (ICE-like apoptotic protease 4) (Apoptotic
           protease Mch-4) (FAS-associated death domain protein
           interleukin-1B-converting enzyme 2) (FLICE2) [Contains:
           Caspase-10 subunit p23/17; Caspase-10 subunit p12]; n=9;
           Eutheria|Rep: Caspase-10 precursor (EC 3.4.22.63)
           (CASP-10) (ICE-like apoptotic protease 4) (Apoptotic
           protease Mch-4) (FAS-associated death domain protein
           interleukin-1B-converting enzyme 2) (FLICE2) [Contains:
           Caspase-10 subunit p23/17; Caspase-10 subunit p12] -
           Homo sapiens (Human)
          Length = 521

 Score = 65.3 bits (152), Expect = 2e-09
 Identities = 34/73 (46%), Positives = 46/73 (63%), Gaps = 4/73 (5%)
 Frame = +3

Query: 39  YFTADKCPTLAGKPKLFFIQACQGDKLDGGITLS----NTETDGXXXXXYRIPIHADFLI 206
           +FTA +CP LA KPKLFFIQACQG+++   +++     N E          IP  ADFL+
Sbjct: 380 HFTALQCPRLAEKPKLFFIQACQGEEIQPSVSIEADALNPE-QAPTSLQDSIPAEADFLL 438

Query: 207 VFSTVPGYYSWRN 245
             +TVPGY S+R+
Sbjct: 439 GLATVPGYVSFRH 451


>UniRef50_Q3HL92 Cluster: Caspase-like protein; n=6; Eumetazoa|Rep:
           Caspase-like protein - Aiptasia pallida (Sea anemone)
          Length = 415

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 30/65 (46%), Positives = 39/65 (60%)
 Frame = +3

Query: 54  KCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTVPGYY 233
           K   L GKPK+F  QACQG +   G+  ++           +IP+ ADFL  +STVPGYY
Sbjct: 279 KGTNLVGKPKIFIFQACQGHEYMDGVDATDAPP---ADKRVQIPVEADFLYAYSTVPGYY 335

Query: 234 SWRNT 248
           SWRN+
Sbjct: 336 SWRNS 340



 Score = 38.7 bits (86), Expect = 0.16
 Identities = 23/60 (38%), Positives = 34/60 (56%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SWF+QS+ E    Y    D+LT++T V   VA   +S T D     ++KQ+P I SM+ +
Sbjct: 344 SWFIQSIAEVFDKYAKTTDLLTMMTRVNALVA-THQSRTND-PYSDRKKQIPSIVSMMRK 401


>UniRef50_Q7QKT2 Cluster: ENSANGP00000015505; n=3; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000015505 - Anopheles gambiae
           str. PEST
          Length = 263

 Score = 64.5 bits (150), Expect = 3e-09
 Identities = 30/75 (40%), Positives = 46/75 (61%), Gaps = 2/75 (2%)
 Frame = +3

Query: 24  DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDG--XXXXXYRIPIHAD 197
           D LW  F  +KCP+L GKPKL FIQ+C+G KLD G +++  +           +IP++AD
Sbjct: 119 DELWTNFVGNKCPSLIGKPKLVFIQSCRGGKLDYGASIATADARPGLEEPVDVKIPMYAD 178

Query: 198 FLIVFSTVPGYYSWR 242
            L+++S+   + S R
Sbjct: 179 LLVMYSSFEHHSSIR 193


>UniRef50_UPI0000E49D20 Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 329

 Score = 63.3 bits (147), Expect = 7e-09
 Identities = 46/135 (34%), Positives = 71/135 (52%), Gaps = 11/135 (8%)
 Frame = +3

Query: 30  LWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXY----------- 176
           L+ +F  +KCPTL GKPKLF IQAC+GD+ + G+      TD                  
Sbjct: 176 LFEFFRGEKCPTLIGKPKLFLIQACRGDRHEIGVDPPVDVTDSAAPEDEWVTVTDSGTRP 235

Query: 177 RIPIHADFLIVFSTVPGYYSWRNTTRALGLCNLFVKN*ETMVLKEIFLHS*HLFVRELL* 356
            IP  AD L+ +S V GYYS R+T  A G  + +++     + K + LH   + + E+L 
Sbjct: 236 TIPAAADMLLSYSVVQGYYSHRDT--AFG--SWYIQ----ALAKVLALHGTTMEITEILT 287

Query: 357 ILSQIHQISHRCINK 401
           +++Q+  IS R + +
Sbjct: 288 LVNQL--ISQRAVER 300



 Score = 40.3 bits (90), Expect = 0.053
 Identities = 23/60 (38%), Positives = 34/60 (56%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SW++Q+L + L  +GT  +I  +LT V Q ++        D   M  +KQ+PC  SMLTR
Sbjct: 263 SWYIQALAKVLALHGTTMEITEILTLVNQLISQRAVERCLD-PRMVGKKQMPCYMSMLTR 321


>UniRef50_Q4RG79 Cluster: Chromosome 2 SCAF15106, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 2 SCAF15106, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 242

 Score = 63.3 bits (147), Expect = 7e-09
 Identities = 41/106 (38%), Positives = 50/106 (47%), Gaps = 28/106 (26%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQ--------------------ACQGDKLDGGITLS----NTE 149
           F  D C +L GKPKLFFIQ                    AC+G + D GI       N  
Sbjct: 83  FRGDMCKSLVGKPKLFFIQFSAETATQDHNEMSSHLLHQACRGSEFDDGIQTDSGPPNDT 142

Query: 150 TDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTR----ALGLCNL 275
            +      ++IP+ ADFL  +STVPGYYSWRN  R       LCN+
Sbjct: 143 METDANPRHKIPVEADFLFAYSTVPGYYSWRNPGRGSWFVQALCNV 188



 Score = 56.0 bits (129), Expect = 1e-06
 Identities = 27/60 (45%), Positives = 39/60 (65%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SWF+Q+LC  L  +G Q +I+ +LT V   VA  FES + D     ++KQ+PC+ SMLT+
Sbjct: 179 SWFVQALCNVLNEFGKQLEIMQILTRVNYMVATSFESWSED-PRFSEKKQIPCVVSMLTK 237


>UniRef50_A7SPA7 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 242

 Score = 62.9 bits (146), Expect = 9e-09
 Identities = 32/70 (45%), Positives = 40/70 (57%), Gaps = 2/70 (2%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNT-ETDGXXXXXYRI-PIHADFLIVFS 215
           F  + CPTLA KPKLFFIQAC+G   D GI    T + D          P  + FL+ ++
Sbjct: 110 FKGNACPTLAHKPKLFFIQACRGQDFDRGIQADATRDMDASDAVRQNAEPNESHFLLGYA 169

Query: 216 TVPGYYSWRN 245
           T PGY SWR+
Sbjct: 170 TPPGYVSWRS 179


>UniRef50_A7S4V9 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 358

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 29/68 (42%), Positives = 39/68 (57%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTV 221
           F   +   L GKPKLFF+QAC+G   D G  +   ++         +P  ADFLI ++TV
Sbjct: 226 FNGYQAKDLIGKPKLFFLQACRGGDFDHGARMEQIDSPTDKSS---LPSEADFLIAYATV 282

Query: 222 PGYYSWRN 245
           PGY SWR+
Sbjct: 283 PGYVSWRH 290



 Score = 40.7 bits (91), Expect = 0.040
 Identities = 23/60 (38%), Positives = 37/60 (61%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SWF+Q+L E  +   T  D+L++L  V ++VAL+FES        +++KQ+P    MLT+
Sbjct: 295 SWFIQALVEVFKTDATTEDVLSMLIKVNRKVALEFES-------FNRKKQMPSPVVMLTK 347


>UniRef50_Q14790 Cluster: Caspase-8 precursor (EC 3.4.22.61)
           (CASP-8) (ICE-like apoptotic protease 5)
           (MORT1-associated CED-3 homolog) (MACH) (FADD-homologous
           ICE/CED-3-like protease) (FADD-like ICE) (FLICE)
           (Apoptotic cysteine protease) (Apoptotic protease Mch-5)
           (CAP4) [Contains: Caspase-8 subunit p18; Caspase-8
           subunit p10]; n=35; Amniota|Rep: Caspase-8 precursor (EC
           3.4.22.61) (CASP-8) (ICE-like apoptotic protease 5)
           (MORT1-associated CED-3 homolog) (MACH) (FADD-homologous
           ICE/CED-3-like protease) (FADD-like ICE) (FLICE)
           (Apoptotic cysteine protease) (Apoptotic protease Mch-5)
           (CAP4) [Contains: Caspase-8 subunit p18; Caspase-8
           subunit p10] - Homo sapiens (Human)
          Length = 479

 Score = 60.9 bits (141), Expect = 4e-08
 Identities = 35/75 (46%), Positives = 41/75 (54%), Gaps = 7/75 (9%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLDGGITLSN-------TETDGXXXXXYRIPIHADF 200
           FT  KCP+LAGKPK+FFIQACQGD    GI +          E D        IP  ADF
Sbjct: 340 FTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADF 399

Query: 201 LIVFSTVPGYYSWRN 245
           L+  +TV    S+RN
Sbjct: 400 LLGMATVNNCVSYRN 414


>UniRef50_UPI00015553DC Cluster: PREDICTED: similar to caspase-15;
           n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to
           caspase-15 - Ornithorhynchus anatinus
          Length = 237

 Score = 60.5 bits (140), Expect = 5e-08
 Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
 Frame = +3

Query: 24  DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNT--ETDGXXXXXYRIPIHAD 197
           + ++  F    CP L  KPK+F IQAC+GD+ DGG+   +   E         R+P  +D
Sbjct: 93  EEIFKLFNNANCPNLREKPKIFIIQACRGDRTDGGVEAFDNVPEEMDDTSNVKRLPTTSD 152

Query: 198 FLIVFSTVPGYYSWRN 245
           F IV+ST  G+ S RN
Sbjct: 153 FFIVYSTQKGHVSVRN 168


>UniRef50_Q9I8J3 Cluster: Caspase-8; n=11; Danio rerio|Rep:
           Caspase-8 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 476

 Score = 60.5 bits (140), Expect = 5e-08
 Identities = 35/77 (45%), Positives = 43/77 (55%), Gaps = 11/77 (14%)
 Frame = +3

Query: 57  CPTLAGKPKLFFIQACQGDKLDGGITLSN-----------TETDGXXXXXYRIPIHADFL 203
           C TLA KPKLFFIQACQGD+   G+  S+            E D       +IPI ADFL
Sbjct: 340 CRTLASKPKLFFIQACQGDENQAGVWTSDGREDAPEEDEEYEEDAGIIVLRKIPIEADFL 399

Query: 204 IVFSTVPGYYSWRNTTR 254
           I  +TV  Y S+R+T +
Sbjct: 400 IGMATVEHYLSYRHTKK 416


>UniRef50_UPI0000E48C15 Cluster: PREDICTED: similar to caspase 8;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to caspase 8 - Strongylocentrotus purpuratus
          Length = 300

 Score = 60.1 bits (139), Expect = 6e-08
 Identities = 40/114 (35%), Positives = 56/114 (49%), Gaps = 4/114 (3%)
 Frame = +3

Query: 24  DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFL 203
           D L   F  D  P+L  KPKLFFIQACQG+   G + +    T         +P ++D L
Sbjct: 161 DALTGLFRGDYVPSLVNKPKLFFIQACQGNDAQGAVDIQQDAT-----ATATLPHNSDTL 215

Query: 204 IVFSTVPGYYSWRNTTRA----LGLCNLFVKN*ETMVLKEIFLHS*HLFVRELL 353
           +  +T+PGY S+RN        + LCN+      T   K++ L S    V EL+
Sbjct: 216 VSHATIPGYASFRNAYSGSLFIISLCNII----NTHYKKKVDLLSMLTMVNELM 265


>UniRef50_Q0WYJ4 Cluster: Caspase 10; n=4; Percomorpha|Rep: Caspase
           10 - Paralichthys olivaceus (Japanese flounder)
          Length = 494

 Score = 59.7 bits (138), Expect = 8e-08
 Identities = 36/86 (41%), Positives = 45/86 (52%), Gaps = 7/86 (8%)
 Frame = +3

Query: 18  KPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXY------- 176
           K ++L     A  CPTLA KPKLFFIQACQG K    + +   E DG             
Sbjct: 340 KINDLMEPLNAHNCPTLAQKPKLFFIQACQGKKGQSAVYI---EADGPATSLICTDAVRD 396

Query: 177 RIPIHADFLIVFSTVPGYYSWRNTTR 254
             P+ ADFLI  +TVP + S+R+  R
Sbjct: 397 SFPVDADFLISMATVPSFVSYRDKQR 422


>UniRef50_Q09HM6 Cluster: Caspase-8; n=1; Molgula tectiformis|Rep:
           Caspase-8 - Molgula tectiformis
          Length = 700

 Score = 59.7 bits (138), Expect = 8e-08
 Identities = 37/104 (35%), Positives = 52/104 (50%), Gaps = 5/104 (4%)
 Frame = +3

Query: 15  YKPDNLWYYFTADKCPTLAGKPKLFFIQACQG-DKLDGGITL----SNTETDGXXXXXYR 179
           ++  ++  +FT   C TL  KPKL FIQAC G ++++G        S+  +DG       
Sbjct: 530 FRISDIQSFFTTTTCSTLQDKPKLVFIQACAGANEMEGKEIQCQQESDIHSDGDDNIKEA 589

Query: 180 IPIHADFLIVFSTVPGYYSWRNTTRALGLCNLFVKN*ETMVLKE 311
            P  ADFL+  ST PGY S+R+T          VKN +    KE
Sbjct: 590 TPFLADFLLANSTWPGYRSYRSTKTGSWFITALVKNLKMYSCKE 633


>UniRef50_A7SXL6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 180

 Score = 59.3 bits (137), Expect = 1e-07
 Identities = 32/76 (42%), Positives = 39/76 (51%)
 Frame = +3

Query: 24  DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFL 203
           D +   F    CP LA KPKLFFIQAC+GD +D G    +            +P  ADFL
Sbjct: 24  DEITGKFQGTNCPQLATKPKLFFIQACRGDDVDKGYR-GHRNHHHEEELPVTLPSEADFL 82

Query: 204 IVFSTVPGYYSWRNTT 251
           I +ST  G  S+R  T
Sbjct: 83  IAYSTTKGKVSFRRYT 98


>UniRef50_A7S119 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 229

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 27/74 (36%), Positives = 45/74 (60%)
 Frame = +3

Query: 24  DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFL 203
           ++L   F    CP+L GKPK+FF+QAC+G K +  +    ++++        +P  +DFL
Sbjct: 95  ESLTNKFRGSTCPSLQGKPKVFFLQACRGAKKE--LVAVESDSEPVPIRHSGLPSDSDFL 152

Query: 204 IVFSTVPGYYSWRN 245
           I +++ PGY S+RN
Sbjct: 153 ICYASSPGYESYRN 166


>UniRef50_Q9NHF9 Cluster: Caspase 6-like protein BG2; n=3;
           Sophophora|Rep: Caspase 6-like protein BG2 - Drosophila
           melanogaster (Fruit fly)
          Length = 308

 Score = 58.4 bits (135), Expect = 2e-07
 Identities = 32/87 (36%), Positives = 42/87 (48%), Gaps = 10/87 (11%)
 Frame = +3

Query: 15  YKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSN----------TETDGXX 164
           Y  + LW  F  D C TL  KPKLFFIQAC+G  L+  +  S+                 
Sbjct: 142 YPVERLWNPFLGDNCKTLKNKPKLFFIQACRGANLEKAVEFSSFAVMTRELVPEPAAAVQ 201

Query: 165 XXXYRIPIHADFLIVFSTVPGYYSWRN 245
              Y IP  AD L+ +ST   ++S+RN
Sbjct: 202 PITYAIPSTADILVFYSTFDKFFSFRN 228



 Score = 39.9 bits (89), Expect = 0.070
 Identities = 24/67 (35%), Positives = 38/67 (56%), Gaps = 7/67 (10%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQR-------DILTLLTFVCQRVALDFESNTPDITPMHQQKQVPC 415
           SWF+QSLC  L              ++L LLT V ++VA +++SNT +   ++Q K++P 
Sbjct: 233 SWFIQSLCRVLDQAAANEAATPEGVELLRLLTAVNRKVAYEYQSNTKN-EALNQMKEMPN 291

Query: 416 INSMLTR 436
             S LT+
Sbjct: 292 FMSTLTK 298


>UniRef50_A2BGE2 Cluster: Novel protein similar to caspase 8; n=4;
           Danio rerio|Rep: Novel protein similar to caspase 8 -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 366

 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 31/80 (38%), Positives = 45/80 (56%), Gaps = 4/80 (5%)
 Frame = +3

Query: 24  DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSN----TETDGXXXXXYRIPIH 191
           D++   F    C +LAGKPK+FFIQAC+G ++   + +++    + T         IP  
Sbjct: 221 DDITSPFNGANCSSLAGKPKVFFIQACRGHEIQSKVMVADGSGGSRTQKPGRVSVSIPKD 280

Query: 192 ADFLIVFSTVPGYYSWRNTT 251
           +DFLI  STV GY S R+ T
Sbjct: 281 SDFLIARSTVEGYVSIRDRT 300


>UniRef50_UPI0000E472FD Cluster: PREDICTED: similar to caspase 8;
           n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to caspase 8 - Strongylocentrotus purpuratus
          Length = 790

 Score = 56.8 bits (131), Expect = 6e-07
 Identities = 36/104 (34%), Positives = 48/104 (46%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTV 221
           F  D  P+L  KPKLFFIQACQG +  G + +    T         +P  +D L+  STV
Sbjct: 663 FRGDYVPSLVNKPKLFFIQACQGREAQGAVDIQQDAT-------ATLPNESDTLVSMSTV 715

Query: 222 PGYYSWRNTTRALGLCNLFVKN*ETMVLKEIFLHS*HLFVRELL 353
           PGY S R+ ++             T   K + L S    V E+L
Sbjct: 716 PGYASNRSVSQGTWFITALCSIINTYYKKNVDLLSMLTLVNEML 759



 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 29/77 (37%), Positives = 39/77 (50%)
 Frame = +3

Query: 24  DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFL 203
           D L   F  +  P+L  KPKLFFIQACQGD     + +    T         +P  +D L
Sbjct: 529 DALTGLFRGEYVPSLVNKPKLFFIQACQGDNAQRAVDIQQDATT-------TLPNESDTL 581

Query: 204 IVFSTVPGYYSWRNTTR 254
           +  STV GY S R+ ++
Sbjct: 582 VSMSTVSGYASNRSVSQ 598


>UniRef50_P55212 Cluster: Caspase-6 precursor (EC 3.4.22.59)
           (CASP-6) (Apoptotic protease Mch-2) [Contains: Caspase-6
           subunit p18; Caspase-6 subunit p11]; n=35;
           Euteleostomi|Rep: Caspase-6 precursor (EC 3.4.22.59)
           (CASP-6) (Apoptotic protease Mch-2) [Contains: Caspase-6
           subunit p18; Caspase-6 subunit p11] - Homo sapiens
           (Human)
          Length = 293

 Score = 56.0 bits (129), Expect = 1e-06
 Identities = 31/80 (38%), Positives = 41/80 (51%), Gaps = 11/80 (13%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLDGGI-----------TLSNTETDGXXXXXYRIPI 188
           F  DKC +L GKPK+F IQAC+G++ D  +            L    T+      Y +P 
Sbjct: 143 FKGDKCHSLVGKPKIFIIQACRGNQHDVPVIPLDVVDNQTEKLDTNITEVDAASVYTLPA 202

Query: 189 HADFLIVFSTVPGYYSWRNT 248
            ADFL+ +S   GYYS R T
Sbjct: 203 GADFLMCYSVAEGYYSHRET 222



 Score = 45.2 bits (102), Expect = 0.002
 Identities = 24/60 (40%), Positives = 35/60 (58%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SW++Q LCE L  YG+  +   LLT V ++V+        D + +  +KQVPC  SMLT+
Sbjct: 226 SWYIQDLCEMLGKYGSSLEFTELLTLVNRKVSQRRVDFCKDPSAI-GKKQVPCFASMLTK 284


>UniRef50_UPI0000ECB87F Cluster: Caspase-10 precursor (EC 3.4.22.63)
           (CASP-10) (ICE-like apoptotic protease 4) (Apoptotic
           protease Mch-4) (FAS-associated death domain protein
           interleukin-1B-converting enzyme 2) (FLICE2) [Contains:
           Caspase-10 subunit p23/17; Caspase-10 subunit p12].;
           n=2; Gallus gallus|Rep: Caspase-10 precursor (EC
           3.4.22.63) (CASP-10) (ICE-like apoptotic protease 4)
           (Apoptotic protease Mch-4) (FAS-associated death domain
           protein interleukin-1B-converting enzyme 2) (FLICE2)
           [Contains: Caspase-10 subunit p23/17; Caspase-10 subunit
           p12]. - Gallus gallus
          Length = 537

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 7/76 (9%)
 Frame = +3

Query: 39  YFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSN-------TETDGXXXXXYRIPIHAD 197
           YFTA +CP L  KPKLFF+QACQG ++   + +         +           IP  AD
Sbjct: 390 YFTAKQCPQLTEKPKLFFVQACQGKEVQRPVYVETDARVPDFSSVPQSTSPSESIPEEAD 449

Query: 198 FLIVFSTVPGYYSWRN 245
           FL+  +T+ GY S+R+
Sbjct: 450 FLLGMATIDGYASFRH 465


>UniRef50_Q5C0Y4 Cluster: SJCHGC07329 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC07329 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 239

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 31/101 (30%), Positives = 49/101 (48%), Gaps = 10/101 (9%)
 Frame = +3

Query: 12  HYKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLD----------GGITLSNTETDGX 161
           H   D L   FT  +CP LAGKPK   IQAC+G++ +            +  ++ E    
Sbjct: 87  HVSIDELVSCFTNKRCPLLAGKPKFILIQACRGEERNHNDSKMGDFLDSLPSNSREISLD 146

Query: 162 XXXXYRIPIHADFLIVFSTVPGYYSWRNTTRALGLCNLFVK 284
                 +P  +D +I ++T+PG+ SWR+ T       +FV+
Sbjct: 147 PSSWLSLPHMSDCVIAYTTLPGFVSWRSETEGSWYVKVFVE 187


>UniRef50_Q16FR8 Cluster: Caspase-1; n=1; Aedes aegypti|Rep:
           Caspase-1 - Aedes aegypti (Yellowfever mosquito)
          Length = 283

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 32/79 (40%), Positives = 44/79 (55%), Gaps = 8/79 (10%)
 Frame = +3

Query: 39  YFTADKCPTLAGKPKLFFIQACQGDKLDGGITL------SNTETD--GXXXXXYRIPIHA 194
           +FT     ++AGKPKLF +QAC+G KLD G+ L      ++   D        Y  P  A
Sbjct: 137 HFTPTALKSMAGKPKLFIVQACRGRKLDRGVQLRAKLIQADCAKDVVDSQSVVYTYPEFA 196

Query: 195 DFLIVFSTVPGYYSWRNTT 251
           D L+V S+  G+YS+RN T
Sbjct: 197 DLLLVMSSHHGHYSFRNET 215


>UniRef50_UPI0000F2DFE7 Cluster: PREDICTED: similar to apoptotic
           cysteine protease proMch4; n=1; Monodelphis
           domestica|Rep: PREDICTED: similar to apoptotic cysteine
           protease proMch4 - Monodelphis domestica
          Length = 452

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 30/76 (39%), Positives = 39/76 (51%), Gaps = 4/76 (5%)
 Frame = +3

Query: 39  YFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYR----IPIHADFLI 206
           YF A +CP LA KPKLFF QACQG  +   + L                  IP+ ADFL+
Sbjct: 310 YFKAHRCPGLANKPKLFFFQACQGPDIQESMLLEEDAKISPPIQVETPQRYIPVEADFLL 369

Query: 207 VFSTVPGYYSWRNTTR 254
             +TV G  + R+T +
Sbjct: 370 GMATVDGCCAIRHTIK 385


>UniRef50_A5JSK5 Cluster: Cysteine protease; n=2; Eukaryota|Rep:
           Cysteine protease - Oryzias latipes (Medaka fish)
           (Japanese ricefish)
          Length = 319

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 27/68 (39%), Positives = 39/68 (57%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTV 221
           F A +   L GKPK+F IQACQG ++  G+ L++ E D        IP  AD L+  +TV
Sbjct: 186 FKASEQSALTGKPKMFLIQACQGGQIHKGVALTDVEAD--DCSTQTIPEEADILVALATV 243

Query: 222 PGYYSWRN 245
             Y ++R+
Sbjct: 244 EDYPAYRH 251


>UniRef50_Q16PQ5 Cluster: Ecdysone-inducible caspase, putative; n=2;
           Culicidae|Rep: Ecdysone-inducible caspase, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 449

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 32/74 (43%), Positives = 41/74 (55%), Gaps = 6/74 (8%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLD-GGITLS-NTETDG----XXXXXYRIPIHADFL 203
           F    CP L  +PKLFF   C+GD  D G + L+ +TE DG           +P +AD L
Sbjct: 307 FNNANCPKLIRRPKLFFFSICRGDNPDYGTLRLAEHTERDGMINLKKDPPTNMPTYADML 366

Query: 204 IVFSTVPGYYSWRN 245
           I FSTVPGY + R+
Sbjct: 367 ICFSTVPGYAAHRD 380


>UniRef50_UPI0000586459 Cluster: PREDICTED: similar to caspase-3,
           partial; n=10; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to caspase-3, partial -
           Strongylocentrotus purpuratus
          Length = 437

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 21/30 (70%), Positives = 26/30 (86%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLDGGI 131
           F +D+CPTL GKPKLFF+QAC+G KLD G+
Sbjct: 261 FCSDRCPTLNGKPKLFFLQACRGKKLDDGV 290



 Score = 39.5 bits (88), Expect = 0.093
 Identities = 21/60 (35%), Positives = 37/60 (61%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SWF+Q+L E +  +  + D+L+++T V  +VA  FES++       + KQ+P   +MLT+
Sbjct: 375 SWFIQALTETILQHAGEEDLLSMITMVNGKVARAFESSS------GRHKQMPAPVTMLTK 428



 Score = 38.3 bits (85), Expect = 0.21
 Identities = 14/35 (40%), Positives = 21/35 (60%)
 Frame = +3

Query: 150 TDGXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTR 254
           TD       ++P  +D L+ ++TVPG+ SWRN  R
Sbjct: 339 TDSFASSRSKVPSQSDMLLAYATVPGFVSWRNAER 373


>UniRef50_Q8I749 Cluster: Caspase-related protein; n=1; Suberites
           domuncula|Rep: Caspase-related protein - Suberites
           domuncula (Sponge)
          Length = 496

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 35/90 (38%), Positives = 46/90 (51%), Gaps = 13/90 (14%)
 Frame = +3

Query: 57  CPTLAGKPKLFFIQACQGDKLDGGI---TLSNTETD------GXXXXXYRIPIHADFLIV 209
           CPTL GKPK+FF+QAC+GD    G     +S TE D      G       IP  ADF   
Sbjct: 359 CPTLRGKPKIFFVQACRGDIESMGFKNEEVSKTEDDLQADMPGGHLHTDTIPQEADFFYG 418

Query: 210 FSTVPGYYSWRNTTRA----LGLCNLFVKN 287
           F+T  GY ++R+          LC +F+K+
Sbjct: 419 FATPLGYAAYRSRRHGSWYISELCQVFIKH 448


>UniRef50_A7S9L1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 262

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 34/82 (41%), Positives = 47/82 (57%), Gaps = 13/82 (15%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLD-GGITLSNTET-DGXXXXXYRIPIH-------- 191
           F+  +C +LAGKPKLFFIQAC+G+K D G I     +T +      Y+  +         
Sbjct: 116 FSNARCRSLAGKPKLFFIQACRGEKKDFGTIVQDGPKTPEEHQETPYKFDLSPHNKGAST 175

Query: 192 ---ADFLIVFSTVPGYYSWRNT 248
              ADFL+ +STV G+ S+RNT
Sbjct: 176 AEMADFLLAYSTVGGHASFRNT 197


>UniRef50_Q9IB64 Cluster: Caspase-8; n=1; Xenopus laevis|Rep:
           Caspase-8 - Xenopus laevis (African clawed frog)
          Length = 500

 Score = 54.0 bits (124), Expect = 4e-06
 Identities = 31/73 (42%), Positives = 39/73 (53%), Gaps = 4/73 (5%)
 Frame = +3

Query: 39  YFTADKCPTLAGKPKLFFIQACQG----DKLDGGITLSNTETDGXXXXXYRIPIHADFLI 206
           YF    C +L  KPK+FFIQACQG     K+D  +  S  E D        +P+ ADFL 
Sbjct: 363 YFNGQHCRSLINKPKIFFIQACQGKESHPKVDMDMDTSFYEPDANGS---HLPLEADFLT 419

Query: 207 VFSTVPGYYSWRN 245
            F+TV  Y S R+
Sbjct: 420 AFATVEDYTSLRH 432


>UniRef50_Q9IB62 Cluster: Caspase-10; n=5; Xenopus|Rep: Caspase-10 -
           Xenopus laevis (African clawed frog)
          Length = 520

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 34/90 (37%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
 Frame = +3

Query: 39  YFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXY--RIPIHADFLIVF 212
           YFTA  C +L  KPKLFFIQACQG        +    +       Y   +P  ADFL+  
Sbjct: 371 YFTATSCISLTLKPKLFFIQACQGIYTHPSSKVEPDASVPVEHKKYIVNVPKEADFLLGM 430

Query: 213 STVPGYYSWRNTTRALGLCNLFVKN*ETMV 302
           STV GY ++R+            KN   MV
Sbjct: 431 STVDGYAAYRHKKYGSWYIQALCKNLVEMV 460


>UniRef50_Q5D0W5 Cluster: Caspase 3C; n=2; Hydra vulgaris|Rep:
           Caspase 3C - Hydra attenuata (Hydra) (Hydra vulgaris)
          Length = 326

 Score = 53.2 bits (122), Expect = 7e-06
 Identities = 28/62 (45%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
 Frame = +3

Query: 66  LAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXX--YRIPIHADFLIVFSTVPGYYSW 239
           LAGKPKLF IQAC+G K    I   +    G         + + +DFL  +STV  YYSW
Sbjct: 189 LAGKPKLFLIQACRGTKYMESIDTVDGFGPGLSNESNVLDVTVESDFLYAYSTVQSYYSW 248

Query: 240 RN 245
           RN
Sbjct: 249 RN 250


>UniRef50_UPI0001554FA5 Cluster: PREDICTED: similar to initiator
           caspase, partial; n=1; Ornithorhynchus anatinus|Rep:
           PREDICTED: similar to initiator caspase, partial -
           Ornithorhynchus anatinus
          Length = 480

 Score = 52.8 bits (121), Expect = 9e-06
 Identities = 27/70 (38%), Positives = 39/70 (55%), Gaps = 3/70 (4%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTE---TDGXXXXXYRIPIHADFLIVF 212
           FT+  C TLA KPK+FF+QACQG +  GG++L   E    +        +P  AD L+  
Sbjct: 334 FTSSACRTLATKPKIFFVQACQGGQGQGGLSLRGREGALLEADAVVIPSVPDWADLLVGM 393

Query: 213 STVPGYYSWR 242
           +TV  +  +R
Sbjct: 394 ATVEDFICFR 403


>UniRef50_Q2HZ04 Cluster: ICE-5; n=3; Bombyx mori|Rep: ICE-5 -
           Bombyx mori (Silk moth)
          Length = 312

 Score = 52.8 bits (121), Expect = 9e-06
 Identities = 26/53 (49%), Positives = 34/53 (64%)
 Frame = +3

Query: 63  TLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTV 221
           TL GKPK+FFIQAC+G  +D G T+     DG      R+P H+DFL + S+V
Sbjct: 158 TLVGKPKIFFIQACRGPFMDEGRTV---VLDGESRSVLRLPTHSDFLFLHSSV 207



 Score = 36.3 bits (80), Expect = 0.86
 Identities = 18/60 (30%), Positives = 32/60 (53%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SW +Q+LCE +R    + D+L ++T V + +A    + TP     + +KQ+      LT+
Sbjct: 247 SWLIQTLCEIIRKNHKEIDLLHMITMVNKSIAYAKSTYTPKCQETNNKKQMSETRFTLTK 306


>UniRef50_UPI00015B57F0 Cluster: PREDICTED: similar to GA20532-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           GA20532-PA - Nasonia vitripennis
          Length = 1390

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 32/90 (35%), Positives = 47/90 (52%), Gaps = 6/90 (6%)
 Frame = +3

Query: 63  TLAGKPKLFFIQACQGDKLDGGI------TLSNTETDGXXXXXYRIPIHADFLIVFSTVP 224
           +L  KPK+FFIQAC+G ++D GI      T S  E DG      ++ I AD    +S+ P
Sbjct: 290 SLINKPKIFFIQACRGPQIDKGICSNEVNTSSEDEVDGNEVFT-KVSIKADIFKAYSSPP 348

Query: 225 GYYSWRNTTRALGLCNLFVKN*ETMVLKEI 314
            + SW+ +     +C  F K  +T  L+ I
Sbjct: 349 DFVSWQASLFIREVCKSFNKYGKTADLETI 378


>UniRef50_Q4JQQ0 Cluster: Initiator caspase; n=2; Gallus gallus|Rep:
           Initiator caspase - Gallus gallus (Chicken)
          Length = 464

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 30/73 (41%), Positives = 40/73 (54%), Gaps = 5/73 (6%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLDGGITL-----SNTETDGXXXXXYRIPIHADFLI 206
           F+   CP+LAGKPKLFFIQACQG      +T+      + ETD        IP  AD L+
Sbjct: 321 FSGSNCPSLAGKPKLFFIQACQGSVGHPAVTVKEDCSGHLETDA--IPALSIPDQADVLV 378

Query: 207 VFSTVPGYYSWRN 245
             +TV  +  +R+
Sbjct: 379 GMATVEDFECYRS 391


>UniRef50_P31944 Cluster: Caspase-14 precursor (EC 3.4.22.-)
           (CASP-14) [Contains: Caspase-14 subunit 1; Caspase-14
           subunit 2]; n=14; Mammalia|Rep: Caspase-14 precursor (EC
           3.4.22.-) (CASP-14) [Contains: Caspase-14 subunit 1;
           Caspase-14 subunit 2] - Homo sapiens (Human)
          Length = 242

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 1/77 (1%)
 Frame = +3

Query: 18  KPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTE-TDGXXXXXYRIPIHA 194
           K +NL+       C  L  KPK++ IQAC+G++ D G T+   E           IP + 
Sbjct: 104 KLENLFEALNNKNCQALRAKPKVYIIQACRGEQRDPGETVGGDEIVMVIKDSPQTIPTYT 163

Query: 195 DFLIVFSTVPGYYSWRN 245
           D L V+STV GY ++R+
Sbjct: 164 DALHVYSTVEGYIAYRH 180


>UniRef50_Q8ITP2 Cluster: AmphiCASP-6; n=2; Chordata|Rep:
           AmphiCASP-6 - Branchiostoma floridae (Florida lancelet)
           (Amphioxus)
          Length = 400

 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 33/81 (40%), Positives = 42/81 (51%), Gaps = 12/81 (14%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQG----------DKLDGGITLSNTETDGXXXXXYR--IP 185
           F AD+C +L GKPKLFFIQAC+G          D+ DG       E         R  +P
Sbjct: 250 FRADRCTSLKGKPKLFFIQACRGAKHEIPVEPLDEPDGLEGSGEAEPMDMVDAGVRPTLP 309

Query: 186 IHADFLIVFSTVPGYYSWRNT 248
             ADFL+ +S   G+YS R+T
Sbjct: 310 AGADFLMAYSVSEGFYSHRDT 330



 Score = 42.7 bits (96), Expect = 0.010
 Identities = 21/60 (35%), Positives = 33/60 (55%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESNTPDITPMHQQKQVPCINSMLTR 436
           SW++Q LC  L+ +GT  ++  +L  V + V+      T D   +   KQ+PC  SMLT+
Sbjct: 334 SWYVQDLCAALKQHGTNMEVHQILALVNRMVSCREVERTTDQRSL-GMKQMPCFLSMLTK 392


>UniRef50_Q6E5N8 Cluster: Caspase 8; n=1; Ictalurus punctatus|Rep:
           Caspase 8 - Ictalurus punctatus (Channel catfish)
          Length = 366

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 34/90 (37%), Positives = 46/90 (51%), Gaps = 15/90 (16%)
 Frame = +3

Query: 24  DNLWYYFTADKCPTLAGKPKLFFIQACQG-----------DKLDGGITLSNTE----TDG 158
           D+++  F+ + CP+L  KPK+F IQAC+G           D  +   T + TE     + 
Sbjct: 209 DDIFGPFSGNSCPSLINKPKVFIIQACRGKEYHLPVEVQPDSYEEEDTEAETEDEKSLET 268

Query: 159 XXXXXYRIPIHADFLIVFSTVPGYYSWRNT 248
                  IP  ADFLI  STV GYYS R+T
Sbjct: 269 DAVQMMTIPADADFLIARSTVKGYYSMRDT 298


>UniRef50_UPI00015B59A2 Cluster: PREDICTED: similar to
           ecdysone-inducible caspase, putative; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to
           ecdysone-inducible caspase, putative - Nasonia
           vitripennis
          Length = 438

 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 9/78 (11%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDK---------LDGGITLSNTETDGXXXXXYRIPIHA 194
           FTA +CP+L  KPK+F  Q C+GDK             +      +D        +  ++
Sbjct: 287 FTAMQCPSLINKPKIFIFQTCRGDKHQQAVVSRFATDAVVTKEASSDSHKPFGVSMRNYS 346

Query: 195 DFLIVFSTVPGYYSWRNT 248
           D +I ++T+PGY S+R+T
Sbjct: 347 DTIIAYATLPGYVSYRDT 364


>UniRef50_Q4FJK5 Cluster: Casp9 protein; n=20; Eutheria|Rep: Casp9
           protein - Mus musculus (Mouse)
          Length = 454

 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 31/90 (34%), Positives = 44/90 (48%), Gaps = 22/90 (24%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDG--------XXXXXYR------ 179
           F    CP+L GKPKLFFIQAC G++ D G  ++ T + G             Y+      
Sbjct: 305 FNGSGCPSLGGKPKLFFIQACGGEQKDHGFEVACTSSQGRTLDSDSEPDAVPYQEGPRPL 364

Query: 180 --------IPIHADFLIVFSTVPGYYSWRN 245
                   +P  +D L+ +ST PG+ SWR+
Sbjct: 365 DQLDAVSSLPTPSDILVSYSTFPGFVSWRD 394


>UniRef50_Q90WU0 Cluster: Caspase 9; n=2; Gallus gallus|Rep: Caspase
           9 - Gallus gallus (Chicken)
          Length = 403

 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 31/91 (34%), Positives = 43/91 (47%), Gaps = 22/91 (24%)
 Frame = +3

Query: 39  YFTADKCPTLAGKPKLFFIQACQGDKLDGGITLS-----------NTETDG--------- 158
           YF   +CP+L GKPKLFFIQAC G++ D G  +            + E+D          
Sbjct: 253 YFNGSQCPSLRGKPKLFFIQACGGEQKDQGFEVDCESPQDETCRRSIESDAIPFQAPSGN 312

Query: 159 --XXXXXYRIPIHADFLIVFSTVPGYYSWRN 245
                    +P   D L+ +ST PG+ SWR+
Sbjct: 313 EDEPDAVASLPTPGDILVSYSTFPGFVSWRD 343


>UniRef50_Q4SC67 Cluster: Chromosome undetermined SCAF14659, whole
           genome shotgun sequence; n=2; Deuterostomia|Rep:
           Chromosome undetermined SCAF14659, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 445

 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 25/94 (26%)
 Frame = +3

Query: 39  YFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETD----GXXXXXYRIPI------ 188
           Y     CP+L GKPKLFFIQAC GD+ D G  +S  E +    G       IP+      
Sbjct: 262 YLNGQYCPSLQGKPKLFFIQACGGDEKDTGFQVSPDEFEPPVVGADDQTDAIPVSSSSDS 321

Query: 189 ---------------HADFLIVFSTVPGYYSWRN 245
                           +D L+ +ST PGY SWR+
Sbjct: 322 LSMSDEPDARASLPTSSDILVSYSTFPGYVSWRD 355


>UniRef50_Q3T2L0 Cluster: Caspase-15; n=11; Theria|Rep: Caspase-15 -
           Bos taurus (Bovine)
          Length = 368

 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
 Frame = +3

Query: 24  DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETD-GXXXXXYRIPIHADF 200
           ++++  F    CP L  KPK+F IQAC+G++ D G+   +   D        R+P  +D+
Sbjct: 231 EDIFEMFNNKNCPALQEKPKIFIIQACRGERRDSGVETDDEPMDLDDGSEKKRLPTFSDY 290

Query: 201 LIVFSTVPGYYSWRN 245
            IV+ T   + + R+
Sbjct: 291 FIVYPTQADHVALRD 305


>UniRef50_A3QVU6 Cluster: Initiator caspase; n=3; Culicidae|Rep:
           Initiator caspase - Aedes aegypti (Yellowfever mosquito)
          Length = 493

 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 26/61 (42%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
 Frame = +3

Query: 66  LAGKPKLFFIQACQGDKLDGGITLS-NTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWR 242
           L GKPKL F+QACQG  L   + ++   E DG         ++ DFL+ +STVPG+ S R
Sbjct: 366 LTGKPKLLFVQACQGSGLQTAVDVAPRLEHDGPSSET-TASVYVDFLVAWSTVPGFASIR 424

Query: 243 N 245
           +
Sbjct: 425 H 425


>UniRef50_UPI000065FEF6 Cluster: Homolog of Ictalurus punctatus
           "Caspase 8.; n=1; Takifugu rubripes|Rep: Homolog of
           Ictalurus punctatus "Caspase 8. - Takifugu rubripes
          Length = 340

 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 27/68 (39%), Positives = 36/68 (52%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTV 221
           F A +   L  KPK+F IQACQG     G+ L + +TD        IP  AD L+  +TV
Sbjct: 211 FKATRQSALVSKPKMFLIQACQGKGTHRGVLLKDLQTD--DCHTLSIPEEADILVATATV 268

Query: 222 PGYYSWRN 245
             Y S+R+
Sbjct: 269 EDYVSFRH 276


>UniRef50_Q28GK9 Cluster: Novel protein; n=1; Xenopus
           tropicalis|Rep: Novel protein - Xenopus tropicalis
           (Western clawed frog) (Silurana tropicalis)
          Length = 239

 Score = 50.0 bits (114), Expect = 7e-05
 Identities = 29/107 (27%), Positives = 55/107 (51%), Gaps = 4/107 (3%)
 Frame = +3

Query: 27  NLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITL-SNTETDGXXXXXYRIPIHADFL 203
           +L+     +  P LAG PKLFF+QAC+G++ D G+ L ++ +T         + +  D +
Sbjct: 99  DLYDILAPNNSPLLAGVPKLFFVQACRGEQFDEGVFLETDGDTCATDAFSLSLNLPRDSV 158

Query: 204 IVFSTVPGYYSWRNTTRAL---GLCNLFVKN*ETMVLKEIFLHS*HL 335
           ++F++  G+ +++N   ++    LCNL       + L  I     H+
Sbjct: 159 LMFASSEGHVAFQNPGGSVFLQTLCNLLEGEERNLELNRILTRLAHM 205


>UniRef50_Q0PKX0 Cluster: Caspase Xa; n=4; Danio rerio|Rep: Caspase
           Xa - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 345

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 34/91 (37%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQG-------DKLDGGITLSNTETDGXXXXXYRIPIHADF 200
           FT   C  L GKPKLFFIQAC+G       +    G   S  E DG       IP   DF
Sbjct: 208 FTGINCQKLVGKPKLFFIQACRGLRKQLCVNAQADGDGESEMEVDG-DDFEITIPSDTDF 266

Query: 201 LIVFSTVPGYYSWRNTTRALGLCNLFVKN*E 293
           LI  ST  G+ S+R   +         +N E
Sbjct: 267 LIARSTTDGHLSYREPDKGSWFIQSLCRNLE 297


>UniRef50_P55211 Cluster: Caspase-9 precursor (EC 3.4.22.62)
           (CASP-9) (ICE-like apoptotic protease 6) (ICE-LAP6)
           (Apoptotic protease Mch-6) (Apoptotic protease-
           activating factor 3) (APAF-3) [Contains: Caspase-9
           subunit p35; Caspase-9 subunit p10]; n=23;
           Tetrapoda|Rep: Caspase-9 precursor (EC 3.4.22.62)
           (CASP-9) (ICE-like apoptotic protease 6) (ICE-LAP6)
           (Apoptotic protease Mch-6) (Apoptotic protease-
           activating factor 3) (APAF-3) [Contains: Caspase-9
           subunit p35; Caspase-9 subunit p10] - Homo sapiens
           (Human)
          Length = 416

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 31/90 (34%), Positives = 41/90 (45%), Gaps = 22/90 (24%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLDGGITL-----------SNTETDG---------- 158
           F    CP+L GKPKLFFIQAC G++ D G  +           SN E D           
Sbjct: 267 FNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTF 326

Query: 159 -XXXXXYRIPIHADFLIVFSTVPGYYSWRN 245
                   +P  +D  + +ST PG+ SWR+
Sbjct: 327 DQLDAISSLPTPSDIFVSYSTFPGFVSWRD 356


>UniRef50_UPI0000E82482 Cluster: PREDICTED: hypothetical protein;
           n=2; Gallus gallus|Rep: PREDICTED: hypothetical protein
           - Gallus gallus
          Length = 266

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 25/81 (30%), Positives = 46/81 (56%), Gaps = 2/81 (2%)
 Frame = +3

Query: 30  LWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIH--ADFL 203
           +++  +A  CP LA +PK+FFIQAC+G  LD G+ +  T++       +   +H   +  
Sbjct: 103 IFHIVSAQNCPALAERPKVFFIQACRGAALDQGVFV-ETDSGQPEPASFSEYLHIPPNTA 161

Query: 204 IVFSTVPGYYSWRNTTRALGL 266
           ++F+  PGY ++ N   ++ L
Sbjct: 162 VMFACSPGYGAFLNPAGSMFL 182


>UniRef50_UPI0000F2DFE8 Cluster: PREDICTED: similar to initiator
           caspase; n=1; Monodelphis domestica|Rep: PREDICTED:
           similar to initiator caspase - Monodelphis domestica
          Length = 473

 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 24/41 (58%), Positives = 27/41 (65%), Gaps = 3/41 (7%)
 Frame = +3

Query: 9   THYKP---DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLD 122
           T +KP     L  YFTA++C TL  KPKLFFIQACQ  K D
Sbjct: 299 TDWKPVAIKKLLSYFTANECKTLKDKPKLFFIQACQNGKSD 339


>UniRef50_Q56VC9 Cluster: Caspase-8; n=3; Euteleostei|Rep: Caspase-8
           - Oryzias latipes (Medaka fish) (Japanese ricefish)
          Length = 481

 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 29/75 (38%), Positives = 37/75 (49%), Gaps = 7/75 (9%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLDGGITL-------SNTETDGXXXXXYRIPIHADF 200
           F + + P+L GKPKLFFIQACQG     G          +  E D        +P  ADF
Sbjct: 341 FPSYRAPSLIGKPKLFFIQACQGTLAQSGYLPGSEVKGDAELEADASSSTSNSVPNDADF 400

Query: 201 LIVFSTVPGYYSWRN 245
           L+  +TV    S+RN
Sbjct: 401 LLGMATVAECKSFRN 415


>UniRef50_Q4V923 Cluster: Zgc:101776 protein; n=8;
           Clupeocephala|Rep: Zgc:101776 protein - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 436

 Score = 47.2 bits (107), Expect = 5e-04
 Identities = 33/96 (34%), Positives = 42/96 (43%), Gaps = 26/96 (27%)
 Frame = +3

Query: 39  YFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETD----GXXXXXYRIPIHA---- 194
           Y     CP+L GKPKLFFIQAC G + D G  +S  +      G       IP+ +    
Sbjct: 277 YLNGQNCPSLQGKPKLFFIQACGGGEKDIGFEVSPDDVQPCIGGIDDEMDAIPMSSSSDS 336

Query: 195 ------------------DFLIVFSTVPGYYSWRNT 248
                             D L+ +ST PGY SWR+T
Sbjct: 337 LSTASDELDARASLPTPSDILVSYSTFPGYVSWRDT 372


>UniRef50_UPI0000F1EFFE Cluster: PREDICTED: hypothetical protein;
           n=4; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 277

 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 27/72 (37%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
 Frame = +3

Query: 27  NLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITL----SNTETDGXXXXXYRIPIHA 194
           NL   ++  + P +  K KLF IQAC+G  LDGG+ L    S++E          IPI  
Sbjct: 121 NLAEIYSCFRSPIMKDKSKLFLIQACRGGDLDGGVELETDSSSSEEQDILSELLSIPI-- 178

Query: 195 DFLIVFSTVPGY 230
           D  + ++T PGY
Sbjct: 179 DTAVTYATSPGY 190


>UniRef50_P42575 Cluster: Caspase-2 precursor (EC 3.4.22.55)
           (CASP-2) (ICH-1 protease) (NEDD2 protein) (Neural
           precursor cell expressed developmentally down- regulated
           protein 2) (NEDD-2) [Contains: Caspase-2 subunit p18;
           Caspase-2 subunit p13; Caspase-2 subunit p12]; n=34;
           Euteleostomi|Rep: Caspase-2 precursor (EC 3.4.22.55)
           (CASP-2) (ICH-1 protease) (NEDD2 protein) (Neural
           precursor cell expressed developmentally down- regulated
           protein 2) (NEDD-2) [Contains: Caspase-2 subunit p18;
           Caspase-2 subunit p13; Caspase-2 subunit p12] - Homo
           sapiens (Human)
          Length = 452

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 12/83 (14%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLDGGITLSN----------TETDG--XXXXXYRIP 185
           F    CP+L  KPK+FFIQAC+GD+ D G+   +           E+D         R+P
Sbjct: 300 FDNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEESDAGKEKLPKMRLP 359

Query: 186 IHADFLIVFSTVPGYYSWRNTTR 254
             +D +  ++ + G  + RNT R
Sbjct: 360 TRSDMICGYACLKGTAAMRNTKR 382


>UniRef50_UPI0000E4A098 Cluster: PREDICTED: similar to CGI-141
           protein; n=2; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to CGI-141 protein -
           Strongylocentrotus purpuratus
          Length = 225

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 17/24 (70%), Positives = 22/24 (91%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGD 113
           F++D CPTL GKPKLFF+QAC+G+
Sbjct: 74  FSSDLCPTLNGKPKLFFLQACRGE 97


>UniRef50_Q9Y1U6 Cluster: Cell death protein CED-3; n=1;
           Pristionchus pacificus|Rep: Cell death protein CED-3 -
           Pristionchus pacificus
          Length = 417

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 11/92 (11%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETD-----------GXXXXXYRIPI 188
           F     P LAGKPK+  +QAC+G++ D G   +++              G      + P 
Sbjct: 271 FNTHNAPHLAGKPKIILLQACRGERKDIGYEETDSGRPFAFLECLGMGGGGMMTRNKRPA 330

Query: 189 HADFLIVFSTVPGYYSWRNTTRALGLCNLFVK 284
            +D L+ ++T   Y SWRN+ +       FV+
Sbjct: 331 ESDILVAYATPAHYVSWRNSEKGSWFIQSFVE 362


>UniRef50_UPI0000F1EBE3 Cluster: PREDICTED: similar to caspase 10;
           n=2; Danio rerio|Rep: PREDICTED: similar to caspase 10 -
           Danio rerio
          Length = 306

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 27/73 (36%), Positives = 39/73 (53%), Gaps = 6/73 (8%)
 Frame = +3

Query: 54  KCPTLAGKPKLFFIQACQGDKLDGGI---TLSNTE---TDGXXXXXYRIPIHADFLIVFS 215
           +C +L  KPKLFFIQAC+G +    +   T +  E             IP  AD+L+  S
Sbjct: 169 RCSSLYQKPKLFFIQACRGTQNQRAVFPQTFTEDEDVLASDAGVPRDSIPEMADYLMAMS 228

Query: 216 TVPGYYSWRNTTR 254
           TVP Y S+R+ ++
Sbjct: 229 TVPWYASYRDKSK 241


>UniRef50_Q9GV89 Cluster: Caspase 3A; n=1; Hydra vulgaris|Rep:
           Caspase 3A - Hydra attenuata (Hydra) (Hydra vulgaris)
          Length = 347

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 30/101 (29%), Positives = 45/101 (44%)
 Frame = +3

Query: 18  KPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHAD 197
           K ++L   F AD  P    KPK+F +QAC+G+K D        +          IP+ +D
Sbjct: 183 KINSLLENFKADNAPAFDKKPKVFIVQACRGEK-DDIRKDGIKDAKRTYYNESTIPMLSD 241

Query: 198 FLIVFSTVPGYYSWRNTTRALGLCNLFVKN*ETMVLKEIFL 320
           F++ +    GY + R+T +        VK       KE FL
Sbjct: 242 FVVAYPCAAGYTALRSTVKGSWFIQELVKCLSIFYDKEDFL 282


>UniRef50_UPI00006A1E20 Cluster: Caspase-9 precursor (EC 3.4.22.62)
           (CASP-9) (ICE-like apoptotic protease 6) (ICE-LAP6)
           (Apoptotic protease Mch-6) (Apoptotic protease-
           activating factor 3) (APAF-3) [Contains: Caspase-9
           subunit p35; Caspase-9 subunit p10].; n=1; Xenopus
           tropicalis|Rep: Caspase-9 precursor (EC 3.4.22.62)
           (CASP-9) (ICE-like apoptotic protease 6) (ICE-LAP6)
           (Apoptotic protease Mch-6) (Apoptotic protease-
           activating factor 3) (APAF-3) [Contains: Caspase-9
           subunit p35; Caspase-9 subunit p10]. - Xenopus
           tropicalis
          Length = 141

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 17/24 (70%), Positives = 19/24 (79%)
 Frame = +3

Query: 39  YFTADKCPTLAGKPKLFFIQACQG 110
           YF   KCP+L GKPK+FFIQAC G
Sbjct: 51  YFNGSKCPSLRGKPKIFFIQACGG 74


>UniRef50_Q4SNC6 Cluster: Chromosome 8 SCAF14543, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 8
           SCAF14543, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 397

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 18/35 (51%), Positives = 24/35 (68%), Gaps = 2/35 (5%)
 Frame = +3

Query: 33  WYYFTADK--CPTLAGKPKLFFIQACQGDKLDGGI 131
           W +   D   CP L  KPK+FFIQAC+GD++D G+
Sbjct: 265 WVFTAFDNAHCPLLQNKPKMFFIQACRGDEMDCGV 299


>UniRef50_Q69HP8 Cluster: Caspase-1-like; n=1; Ciona
           intestinalis|Rep: Caspase-1-like - Ciona intestinalis
           (Transparent sea squirt)
          Length = 254

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 16/25 (64%), Positives = 23/25 (92%)
 Frame = +3

Query: 45  TADKCPTLAGKPKLFFIQACQGDKL 119
           +A +CP+LAGKPKLFF+QAC+G ++
Sbjct: 163 SATECPSLAGKPKLFFVQACRGKEI 187


>UniRef50_UPI0000F21D96 Cluster: PREDICTED: hypothetical protein,
           partial; n=1; Danio rerio|Rep: PREDICTED: hypothetical
           protein, partial - Danio rerio
          Length = 170

 Score = 43.6 bits (98), Expect = 0.006
 Identities = 18/36 (50%), Positives = 23/36 (63%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTE 149
           F  DKC +L GKPK+F  QAC+GDK D  +   + E
Sbjct: 123 FKGDKCRSLVGKPKIFIWQACRGDKKDDPVAPMSAE 158


>UniRef50_A2I5C3 Cluster: Putative caspase 3; n=1; Mytilus
           galloprovincialis|Rep: Putative caspase 3 - Mytilus
           galloprovincialis (Mediterranean mussel)
          Length = 56

 Score = 43.6 bits (98), Expect = 0.006
 Identities = 19/42 (45%), Positives = 25/42 (59%)
 Frame = +3

Query: 6   ETHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGI 131
           +T  K  +   YF A+ C  L  KPK+F IQAC+G  L GG+
Sbjct: 14  DTSIKMKSFLSYFNAENCKELQLKPKIFIIQACRGTGLGGGV 55


>UniRef50_Q4S1R8 Cluster: Chromosome undetermined SCAF14764, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF14764, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 279

 Score = 43.2 bits (97), Expect = 0.008
 Identities = 23/78 (29%), Positives = 46/78 (58%), Gaps = 5/78 (6%)
 Frame = +3

Query: 27  NLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITL---SNTETDGXXXXXYR--IPIH 191
           +++ YF  +KC  +  K K+F IQAC+GD LD G+ +   ++ + D      ++  + + 
Sbjct: 107 HIFAYFD-NKC--MEKKTKVFLIQACRGDALDDGVEVDAAADADADASAACVFQQCLSVP 163

Query: 192 ADFLIVFSTVPGYYSWRN 245
            D +++++T PGY ++ N
Sbjct: 164 LDTVVMYATAPGYAAFMN 181


>UniRef50_UPI0000F2CF2E Cluster: PREDICTED: similar to caspase 12;
           n=1; Monodelphis domestica|Rep: PREDICTED: similar to
           caspase 12 - Monodelphis domestica
          Length = 405

 Score = 41.9 bits (94), Expect = 0.017
 Identities = 19/37 (51%), Positives = 25/37 (67%)
 Frame = +3

Query: 24  DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGIT 134
           D ++  F    CP+L GKPK+  IQAC+G+KL  GIT
Sbjct: 259 DVIFQIFNDSNCPSLKGKPKVIIIQACRGEKL--GIT 293


>UniRef50_UPI0000D56041 Cluster: PREDICTED: similar to CG7486-PB,
           isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG7486-PB, isoform B - Tribolium castaneum
          Length = 568

 Score = 41.9 bits (94), Expect = 0.017
 Identities = 24/64 (37%), Positives = 34/64 (53%), Gaps = 2/64 (3%)
 Frame = +3

Query: 60  PTLAGKPKLFFIQACQGDKLDG-GITLSNTETDGXXXXXYR-IPIHADFLIVFSTVPGYY 233
           P L+GKPK+  +Q+CQG +         + ETDG        +P  AD    ++TVPGY 
Sbjct: 437 PHLSGKPKVLILQSCQGTRCQKIQSDDDDIETDGPSSPVQESVPPIADLFTFWATVPGYG 496

Query: 234 SWRN 245
           + RN
Sbjct: 497 AIRN 500


>UniRef50_UPI0000E45DDA Cluster: PREDICTED: similar to caspase 3;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to caspase 3 - Strongylocentrotus purpuratus
          Length = 526

 Score = 41.5 bits (93), Expect = 0.023
 Identities = 29/93 (31%), Positives = 40/93 (43%), Gaps = 22/93 (23%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQG----------------------DKLDGGITLSNTETD 155
           F+  +CP L GKPK+FFIQAC+G                      D  D     S   TD
Sbjct: 323 FSGRQCPALLGKPKIFFIQACRGQMRTKSALDTDDPRRLSPIEMVDDPDIDSCSSRRPTD 382

Query: 156 GXXXXXYRIPIHADFLIVFSTVPGYYSWRNTTR 254
                   +P +AD  + ++T  GY+S RN  +
Sbjct: 383 DAVDIDGDVPDNADIYVAYATSEGYFSIRNQVK 415


>UniRef50_Q9I9L7 Cluster: Caspase; n=2; Danio rerio|Rep: Caspase -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 383

 Score = 41.5 bits (93), Expect = 0.023
 Identities = 30/104 (28%), Positives = 50/104 (48%), Gaps = 6/104 (5%)
 Frame = +3

Query: 24  DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIH--AD 197
           DN++    ++ CP L  KPK+  IQAC+G +  G +  S+ E D          +H   D
Sbjct: 244 DNVYRRLNSENCPALRDKPKVILIQACRGGE-HGRVWASDGEPDEPIEIEDDDFVHKEKD 302

Query: 198 FLIVFSTVPGYYSWRN----TTRALGLCNLFVKN*ETMVLKEIF 317
           F+ + S  P   S+R+    T     L ++F+K      ++E+F
Sbjct: 303 FISLMSCTPDTKSYRHVQNGTFYVQTLVDVFIKCAHEDHIEELF 346


>UniRef50_P55865 Cluster: Caspase-1-A precursor; n=3; Xenopus|Rep:
           Caspase-1-A precursor - Xenopus laevis (African clawed
           frog)
          Length = 386

 Score = 41.5 bits (93), Expect = 0.023
 Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
 Frame = +3

Query: 24  DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDG-XXXXXYRIPIHADF 200
           D ++  F    C  L  KPK+  IQAC+G+   G +   +  +        + +   ADF
Sbjct: 248 DEIFSTFNNVNCSKLRNKPKVIIIQACRGENKGGLLVRDDVASPPLEDDGLHFVQREADF 307

Query: 201 LIVFSTVPGYYSWRNTTR 254
           +   S+ P   SWR+ T+
Sbjct: 308 ICFCSSTPDTVSWRDPTK 325


>UniRef50_Q0Z8U7 Cluster: Caspase-8; n=1; Haemaphysalis
           longicornis|Rep: Caspase-8 - Haemaphysalis longicornis
           (Bush tick)
          Length = 306

 Score = 41.1 bits (92), Expect = 0.030
 Identities = 16/27 (59%), Positives = 20/27 (74%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLD 122
           F    CP+L GKPKLFF+QAC+G + D
Sbjct: 156 FNDSNCPSLQGKPKLFFVQACRGREDD 182


>UniRef50_P29466-2 Cluster: Isoform Beta of P29466 ; n=11;
           Theria|Rep: Isoform Beta of P29466 - Homo sapiens
           (Human)
          Length = 383

 Score = 40.3 bits (90), Expect = 0.053
 Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 11/76 (14%)
 Frame = +3

Query: 57  CPTLAGKPKLFFIQACQGDK-----------LDGGITLSNTETDGXXXXXYRIPIHADFL 203
           CP+L  KPK+  IQAC+GD            + G ++L  TE +       +  I  DF+
Sbjct: 249 CPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTE-EFEDDAIKKAHIEKDFI 307

Query: 204 IVFSTVPGYYSWRNTT 251
              S+ P   SWR+ T
Sbjct: 308 AFCSSTPDNVSWRHPT 323


>UniRef50_P29466 Cluster: Caspase-1 precursor (EC 3.4.22.36)
           (CASP-1) (Interleukin-1 beta convertase) (IL-1BC) (IL-1
           beta-converting enzyme) (ICE) (Interleukin- 1
           beta-converting enzyme) (p45) [Contains: Caspase-1
           subunit p20; Caspase-1 subunit p10]; n=29; Eutheria|Rep:
           Caspase-1 precursor (EC 3.4.22.36) (CASP-1)
           (Interleukin-1 beta convertase) (IL-1BC) (IL-1
           beta-converting enzyme) (ICE) (Interleukin- 1
           beta-converting enzyme) (p45) [Contains: Caspase-1
           subunit p20; Caspase-1 subunit p10] - Homo sapiens
           (Human)
          Length = 404

 Score = 40.3 bits (90), Expect = 0.053
 Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 11/76 (14%)
 Frame = +3

Query: 57  CPTLAGKPKLFFIQACQGDK-----------LDGGITLSNTETDGXXXXXYRIPIHADFL 203
           CP+L  KPK+  IQAC+GD            + G ++L  TE +       +  I  DF+
Sbjct: 270 CPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTE-EFEDDAIKKAHIEKDFI 328

Query: 204 IVFSTVPGYYSWRNTT 251
              S+ P   SWR+ T
Sbjct: 329 AFCSSTPDNVSWRHPT 344


>UniRef50_Q7ZXD2 Cluster: MGC53258 protein; n=3; Xenopus|Rep:
           MGC53258 protein - Xenopus laevis (African clawed frog)
          Length = 419

 Score = 39.9 bits (89), Expect = 0.070
 Identities = 14/25 (56%), Positives = 19/25 (76%)
 Frame = +3

Query: 57  CPTLAGKPKLFFIQACQGDKLDGGI 131
           CP L  KPK+FF QAC+G++ D G+
Sbjct: 273 CPQLQNKPKMFFFQACRGEETDRGV 297


>UniRef50_Q504J1 Cluster: Caspase b; n=7; Danio rerio|Rep: Caspase b
           - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 404

 Score = 39.9 bits (89), Expect = 0.070
 Identities = 21/77 (27%), Positives = 36/77 (46%)
 Frame = +3

Query: 15  YKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHA 194
           Y  +  + +  +  CP L  KPK+  IQAC+G +  G +       D        + +  
Sbjct: 267 YFIEETFSHLNSVNCPALIDKPKVILIQACRGGQSSGVLA-----QDSVFASDSWVHMEK 321

Query: 195 DFLIVFSTVPGYYSWRN 245
           DF+   ST+P  +++RN
Sbjct: 322 DFVCFMSTMPNTFAYRN 338


>UniRef50_UPI0000E47913 Cluster: PREDICTED: similar to cysteine
           protease CPP32 isoform alpha; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to cysteine protease
           CPP32 isoform alpha - Strongylocentrotus purpuratus
          Length = 505

 Score = 39.5 bits (88), Expect = 0.093
 Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 8/76 (10%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKLDGGITLS-------NTET-DGXXXXXYRIPIHAD 197
           F  D+ P +  KPK+F IQ+C+G +   G++ S       N ET D         P+++D
Sbjct: 364 FHGDQIPKMQDKPKVFIIQSCRGKEKQRGVSSSDGPATELNPETMDYPEPAVTTRPVNSD 423

Query: 198 FLIVFSTVPGYYSWRN 245
            LI ++T     ++RN
Sbjct: 424 ILIAYATSQSKKAFRN 439


>UniRef50_UPI000155BC01 Cluster: PREDICTED: similar to cellular
           FLICE-like inhibitory protein long form; n=1;
           Ornithorhynchus anatinus|Rep: PREDICTED: similar to
           cellular FLICE-like inhibitory protein long form -
           Ornithorhynchus anatinus
          Length = 508

 Score = 39.1 bits (87), Expect = 0.12
 Identities = 15/21 (71%), Positives = 17/21 (80%)
 Frame = +3

Query: 39  YFTADKCPTLAGKPKLFFIQA 101
           +FT D CP L GKPKLFFIQ+
Sbjct: 369 FFTGDACPALLGKPKLFFIQS 389


>UniRef50_Q07BT4 Cluster: Caspase-1; n=2; Percomorpha|Rep: Caspase-1
           - Dicentrarchus labrax (European sea bass)
          Length = 394

 Score = 39.1 bits (87), Expect = 0.12
 Identities = 15/41 (36%), Positives = 28/41 (68%)
 Frame = +3

Query: 24  DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNT 146
           +N++ +  ++KCP L  KPK+  IQAC+G+   G + +S++
Sbjct: 240 NNIYEHLGSEKCPALLNKPKIIIIQACRGN-AGGAVLVSDS 279


>UniRef50_UPI0000E47F37 Cluster: PREDICTED: similar to caspase-3,
           partial; n=3; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to caspase-3, partial -
           Strongylocentrotus purpuratus
          Length = 608

 Score = 38.7 bits (86), Expect = 0.16
 Identities = 13/26 (50%), Positives = 19/26 (73%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQACQGDKL 119
           F+ + CP L GKPK+   QAC+G+K+
Sbjct: 105 FSGNNCPALIGKPKIMIFQACRGEKI 130


>UniRef50_Q178B7 Cluster: Caspase-3; n=2; Aedes aegypti|Rep:
           Caspase-3 - Aedes aegypti (Yellowfever mosquito)
          Length = 391

 Score = 38.7 bits (86), Expect = 0.16
 Identities = 31/84 (36%), Positives = 36/84 (42%)
 Frame = +3

Query: 63  TLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSWR 242
           TL GKPKLFF+QAC+GD +         E D       +     D L  FST  G  S+R
Sbjct: 283 TLKGKPKLFFVQACKGDAV--------MEADATRTATNKF----DILKCFSTYEGTLSFR 330

Query: 243 NTTRALGLCNLFVKN*ETMVLKEI 314
            TT          K  E    KEI
Sbjct: 331 YTTEGTTFIQTLFKLIEQNSDKEI 354


>UniRef50_Q9XYF4 Cluster: Caspase Nc precursor (EC 3.4.22.-)
           (NEDD2-like caspase DRONC) [Contains: Caspase Nc subunit
           1; Caspase Nc subunit 2]; n=2; Sophophora|Rep: Caspase
           Nc precursor (EC 3.4.22.-) (NEDD2-like caspase DRONC)
           [Contains: Caspase Nc subunit 1; Caspase Nc subunit 2] -
           Drosophila melanogaster (Fruit fly)
          Length = 450

 Score = 38.7 bits (86), Expect = 0.16
 Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 17/86 (19%)
 Frame = +3

Query: 39  YFTADKCPTLAGKPKLFFIQACQGDKLDGGITLS-----------------NTETDGXXX 167
           +F   KCP L  KPK+     C+GD+ D G   +                 +T+T+G   
Sbjct: 297 HFQTAKCPYLVNKPKVLMFPFCRGDEYDLGHPKNQGNLMEPVYTAQEEKWPDTQTEGIPS 356

Query: 168 XXYRIPIHADFLIVFSTVPGYYSWRN 245
               +P  AD L+ ++  PGY + R+
Sbjct: 357 PSTNVPSLADTLVCYANTPGYVTHRD 382


>UniRef50_Q0Z855 Cluster: Caspase-2; n=1; Haemaphysalis
           longicornis|Rep: Caspase-2 - Haemaphysalis longicornis
           (Bush tick)
          Length = 340

 Score = 37.9 bits (84), Expect = 0.28
 Identities = 16/35 (45%), Positives = 21/35 (60%)
 Frame = +3

Query: 27  NLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGI 131
           +++  F  + CP L GKPKLFFI   +G   D GI
Sbjct: 120 DVYQLFDNENCPNLRGKPKLFFIPGSRGCMWDNGI 154


>UniRef50_A6NFM5 Cluster: Uncharacterized protein ENSP00000371619;
           n=11; Eutheria|Rep: Uncharacterized protein
           ENSP00000371619 - Homo sapiens (Human)
          Length = 408

 Score = 37.9 bits (84), Expect = 0.28
 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
 Frame = +3

Query: 54  KCPTLAGKPKLFFIQACQGDKLDGGITLSNTETD-GXXXXXYRIPIHADFLIVFSTVPG 227
           +C  L G+PK+F +QAC+G   D G+  +              +P HAD L +++   G
Sbjct: 254 RCQVLQGRPKIFLLQACRGGNRDAGVGPTALPWYWSWLRAPPSVPSHADVLQIYAEAQG 312


>UniRef50_P42573 Cluster: Cell death protein 3 precursor (EC
           3.4.22.-) [Contains: Cell death protein 3 subunit 1;
           Cell death protein 3 subunit 2]; n=3;
           Caenorhabditis|Rep: Cell death protein 3 precursor (EC
           3.4.22.-) [Contains: Cell death protein 3 subunit 1;
           Cell death protein 3 subunit 2] - Caenorhabditis elegans
          Length = 503

 Score = 37.5 bits (83), Expect = 0.37
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +3

Query: 48  ADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDG 158
           A   P LA KPK+ F+QAC+G++ D G  + ++  DG
Sbjct: 340 AANAPRLANKPKIVFVQACRGERRDNGFPVLDS-VDG 375



 Score = 35.9 bits (79), Expect = 1.1
 Identities = 14/38 (36%), Positives = 25/38 (65%)
 Frame = +2

Query: 257 SWFMQSLCEELRNYGTQRDILTLLTFVCQRVALDFESN 370
           SWF+Q++CE    +    D++ LLT V ++VA  F+++
Sbjct: 435 SWFIQAVCEVFSTHAKDMDVVELLTEVNKKVACGFQTS 472


>UniRef50_UPI0000661247 Cluster: Homolog of Brachydanio rerio
           "Caspase.; n=4; Takifugu rubripes|Rep: Homolog of
           Brachydanio rerio "Caspase. - Takifugu rubripes
          Length = 358

 Score = 37.1 bits (82), Expect = 0.50
 Identities = 13/31 (41%), Positives = 20/31 (64%)
 Frame = +3

Query: 24  DNLWYYFTADKCPTLAGKPKLFFIQACQGDK 116
           D ++ +   + CP L  KPK+  IQAC+GD+
Sbjct: 213 DKIYRHLGPEHCPALLNKPKIIIIQACRGDE 243


>UniRef50_A3QU14 Cluster: DNA polymerase; n=1; Oryctes rhinoceros
            virus|Rep: DNA polymerase - Oryctes rhinoceros virus
          Length = 1280

 Score = 37.1 bits (82), Expect = 0.50
 Identities = 21/79 (26%), Positives = 37/79 (46%)
 Frame = -3

Query: 502  WYSILMRRFRKFIKLFFSKQEKACQHTIYARYLFLLMHRCDIWCI*LKI*SNSLTNKCQE 323
            +Y  +       IK    K  +    T+ ++Y+ LLM +  +        ++++T K   
Sbjct: 1193 YYQNMYTTIFNLIKFHIKKNNEPYNITLSSKYILLLMLKGFLDAYEATFLTHAVTCKSDV 1252

Query: 322  CKNISLSTIVSQFFTKRLH 266
            C NISLS+   Q FT+ +H
Sbjct: 1253 CNNISLSSDADQIFTEPIH 1271


>UniRef50_UPI0000F2CF2D Cluster: PREDICTED: similar to
           evolutionarily related interleukin-1beta converting
           enzyme; n=1; Monodelphis domestica|Rep: PREDICTED:
           similar to evolutionarily related interleukin-1beta
           converting enzyme - Monodelphis domestica
          Length = 372

 Score = 36.7 bits (81), Expect = 0.65
 Identities = 22/83 (26%), Positives = 33/83 (39%), Gaps = 9/83 (10%)
 Frame = +3

Query: 24  DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSNTETDG---------XXXXXY 176
           D ++       CP L  KPK+  IQAC+G K    +   + E                 +
Sbjct: 228 DTIFNILNTKNCPKLKDKPKVIIIQACRGVKSGKVLMRDSPEISEDSEINPELLEEDAIF 287

Query: 177 RIPIHADFLIVFSTVPGYYSWRN 245
              +  DF+  FS+ P   SWR+
Sbjct: 288 ETHVEKDFISFFSSTPNNVSWRD 310


>UniRef50_UPI000065DDFC Cluster: CASP8 and FADD-like apoptosis
           regulator precursor (Cellular FLICE-like inhibitory
           protein) (c-FLIP) (Caspase-eight-related protein)
           (Casper) (Caspase-like apoptosis regulatory protein)
           (CLARP) (MACH-related inducer of toxicity) (MRIT)
           (Caspase homolog) (C; n=1; Takifugu rubripes|Rep: CASP8
           and FADD-like apoptosis regulator precursor (Cellular
           FLICE-like inhibitory protein) (c-FLIP)
           (Caspase-eight-related protein) (Casper) (Caspase-like
           apoptosis regulatory protein) (CLARP) (MACH-related
           inducer of toxicity) (MRIT) (Caspase homolog) (C -
           Takifugu rubripes
          Length = 472

 Score = 36.7 bits (81), Expect = 0.65
 Identities = 16/25 (64%), Positives = 18/25 (72%)
 Frame = +3

Query: 24  DNLWYYFTADKCPTLAGKPKLFFIQ 98
           D++   FTA  CP LAGKPKL FIQ
Sbjct: 332 DSVSQQFTAKGCPALAGKPKLLFIQ 356


>UniRef50_Q498I3 Cluster: LOC780745 protein; n=6; Xenopus|Rep:
           LOC780745 protein - Xenopus laevis (African clawed frog)
          Length = 512

 Score = 36.7 bits (81), Expect = 0.65
 Identities = 14/25 (56%), Positives = 17/25 (68%)
 Frame = +3

Query: 24  DNLWYYFTADKCPTLAGKPKLFFIQ 98
           D + + FT   CP L GKPKLFF+Q
Sbjct: 377 DRIKHIFTGKSCPDLLGKPKLFFVQ 401


>UniRef50_P51878 Cluster: Caspase-5 precursor (EC 3.4.22.58)
           (CASP-5) (ICH-3 protease) (TY protease) (ICE(rel)-III)
           [Contains: Caspase-5 subunit p20; Caspase-5 subunit
           p10]; n=25; Eutheria|Rep: Caspase-5 precursor (EC
           3.4.22.58) (CASP-5) (ICH-3 protease) (TY protease)
           (ICE(rel)-III) [Contains: Caspase-5 subunit p20;
           Caspase-5 subunit p10] - Homo sapiens (Human)
          Length = 418

 Score = 36.3 bits (80), Expect = 0.86
 Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 10/87 (11%)
 Frame = +3

Query: 24  DNLWYYFTADKCPTLAGKPKLFFIQACQGDK------LDGGITL----SNTETDGXXXXX 173
           D ++  F    C +L  KPK+  +QAC+G+K       D   +L    S +  +      
Sbjct: 273 DTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLAVISSQSSENLEADSV 332

Query: 174 YRIPIHADFLIVFSTVPGYYSWRNTTR 254
            +I    DF+   S+ P   SWR+ TR
Sbjct: 333 CKIHEEKDFIAFCSSTPHNVSWRDRTR 359


>UniRef50_O15519-8 Cluster: Isoform 8 of O15519 ; n=3;
           Homo/Pan/Gorilla group|Rep: Isoform 8 of O15519 - Homo
           sapiens (Human)
          Length = 445

 Score = 35.9 bits (79), Expect = 1.1
 Identities = 14/19 (73%), Positives = 15/19 (78%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQ 98
           F  D CP LAGKPK+FFIQ
Sbjct: 305 FMGDSCPYLAGKPKMFFIQ 323


>UniRef50_O15519 Cluster: CASP8 and FADD-like apoptosis regulator
           precursor (Cellular FLICE-like inhibitory protein)
           (c-FLIP) (Caspase-eight-related protein) (Casper)
           (Caspase-like apoptosis regulatory protein) (CLARP)
           (MACH-related inducer of toxicity) (MRIT) (Caspase
           homolog) (CASH) (Inhibitor of FLICE) (I-FLICE)
           (FADD-like antiapoptotic molecule 1) (FLAME-1) (Usurpin)
           [Contains: CASP8 and FADD-like apoptosis regulator
           subunit p43; CASP8 and FADD-like apoptosis regulator
           subunit p12]; n=46; Amniota|Rep: CASP8 and FADD-like
           apoptosis regulator precursor (Cellular FLICE-like
           inhibitory protein) (c-FLIP) (Caspase-eight-related
           protein) (Casper) (Caspase-like apoptosis regulatory
           protein) (CLARP) (MACH-related inducer of toxicity)
           (MRIT) (Caspase homolog) (CASH) (Inhibitor of FLICE)
           (I-FLICE) (FADD-like antiapoptotic molecule 1) (FLAME-1)
           (Usurpin) [Contains: CASP8 and FADD-like apoptosis
           regulator subunit p43; CASP8 and FADD-like apoptosis
           regulator subunit p12] - Homo sapiens (Human)
          Length = 480

 Score = 35.9 bits (79), Expect = 1.1
 Identities = 14/19 (73%), Positives = 15/19 (78%)
 Frame = +3

Query: 42  FTADKCPTLAGKPKLFFIQ 98
           F  D CP LAGKPK+FFIQ
Sbjct: 340 FMGDSCPYLAGKPKMFFIQ 358


>UniRef50_UPI000051A33A Cluster: PREDICTED: similar to CG6597-PA,
           isoform A; n=2; Coelomata|Rep: PREDICTED: similar to
           CG6597-PA, isoform A - Apis mellifera
          Length = 478

 Score = 35.5 bits (78), Expect = 1.5
 Identities = 14/28 (50%), Positives = 16/28 (57%)
 Frame = +3

Query: 15  YKPDNLWYYFTADKCPTLAGKPKLFFIQ 98
           Y    LW  F  D CP L  KPK+FF+Q
Sbjct: 166 YPAQMLWMPFLPDSCPGLIDKPKIFFLQ 193


>UniRef50_O42284 Cluster: Caspase-1; n=3; Gallus gallus|Rep:
           Caspase-1 - Gallus gallus (Chicken)
          Length = 283

 Score = 35.1 bits (77), Expect = 2.0
 Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 14/90 (15%)
 Frame = +3

Query: 24  DNLWYYFTADKCPTLAGKPKLFFIQACQGDKLDGGITLSN--------TETDGXXXXXYR 179
           + ++  F    C  L GKPK+  IQ C+GD + G + + +        + +DG      +
Sbjct: 137 NTIYENFNNKHCRALMGKPKVVIIQCCRGDNI-GSVQIRDSIDPEMPTSTSDGWRCVELQ 195

Query: 180 ------IPIHADFLIVFSTVPGYYSWRNTT 251
                   + +DF  ++S+ P   SWR+ T
Sbjct: 196 GSKTREAHLESDFATLYSSTPDTVSWRSPT 225


>UniRef50_Q7KHK9 Cluster: DREAM; n=2; Sophophora|Rep: DREAM -
           Drosophila melanogaster (Fruit fly)
          Length = 527

 Score = 34.3 bits (75), Expect = 3.5
 Identities = 15/32 (46%), Positives = 19/32 (59%)
 Frame = +3

Query: 63  TLAGKPKLFFIQACQGDKLDGGITLSNTETDG 158
           TL  KPKL F+QAC+GD   GG      + +G
Sbjct: 416 TLKDKPKLIFVQACKGDCQLGGFMTDAAQPNG 447


>UniRef50_P29466-4 Cluster: Isoform Delta of P29466 ; n=2;
           Euarchontoglires|Rep: Isoform Delta of P29466 - Homo
           sapiens (Human)
          Length = 263

 Score = 33.5 bits (73), Expect = 6.1
 Identities = 12/21 (57%), Positives = 16/21 (76%)
 Frame = +3

Query: 57  CPTLAGKPKLFFIQACQGDKL 119
           CP+L  KPK+  IQAC+GD +
Sbjct: 177 CPSLKDKPKVIIIQACRGDNV 197


>UniRef50_Q74BT1 Cluster: Fibronectin type III domain protein; n=2;
           Geobacter|Rep: Fibronectin type III domain protein -
           Geobacter sulfurreducens
          Length = 1047

 Score = 33.5 bits (73), Expect = 6.1
 Identities = 19/75 (25%), Positives = 28/75 (37%)
 Frame = +3

Query: 60  PTLAGKPKLFFIQACQGDKLDGGITLSNTETDGXXXXXYRIPIHADFLIVFSTVPGYYSW 239
           P+    P +       G  + G +T+S T +D          ++       +T P  YSW
Sbjct: 689 PSDTAAPTVAVSAPANGATVSGTVTVSATASDNVGVTKVEFMVNGTVASTVTTAPYSYSW 748

Query: 240 RNTTRALGLCNLFVK 284
             TT A G   L  K
Sbjct: 749 NTTTSANGTYTLTAK 763


>UniRef50_Q9NBW3 Cluster: Cysteine protease; n=4; melanogaster
           subgroup|Rep: Cysteine protease - Drosophila
           melanogaster (Fruit fly)
          Length = 255

 Score = 33.1 bits (72), Expect = 8.1
 Identities = 16/35 (45%), Positives = 22/35 (62%)
 Frame = +3

Query: 6   ETHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQG 110
           E H   D L+  F   + PTL+GKPK+  +QAC+G
Sbjct: 127 EYHLDDDVLFPLF---RNPTLSGKPKILIVQACKG 158


>UniRef50_Q8I5D6 Cluster: Putative uncharacterized protein; n=3;
           Plasmodium|Rep: Putative uncharacterized protein -
           Plasmodium falciparum (isolate 3D7)
          Length = 818

 Score = 33.1 bits (72), Expect = 8.1
 Identities = 16/36 (44%), Positives = 19/36 (52%)
 Frame = -3

Query: 781 NNYNL*DLKKPTFIYL*NIHIYCQ*KKYHLSFFHHN 674
           NNY+  + KK T  Y  N H Y     Y+ SF HHN
Sbjct: 229 NNYSFINKKKYTQYYNNNTHSYFHIYNYYSSFIHHN 264


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 718,615,777
Number of Sequences: 1657284
Number of extensions: 14127260
Number of successful extensions: 30109
Number of sequences better than 10.0: 121
Number of HSP's better than 10.0 without gapping: 28753
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 30030
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 66262109095
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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