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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= maV30038
         (529 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial pre...   164   1e-39
UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial pre...   162   5e-39
UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazo...   146   3e-34
UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast precu...   143   3e-33
UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep...   140   2e-32
UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal precu...   135   7e-31
UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3; ...   126   3e-28
UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Re...   124   1e-27
UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida glab...   120   3e-26
UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5; Protostomia|...   118   6e-26
UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella ve...   117   1e-25
UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1; ...   117   1e-25
UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24...   111   7e-24
UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3; Le...   111   1e-23
UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|R...   106   3e-22
UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep: A...   104   1e-21
UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9; T...   102   6e-21
UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;...   100   4e-20
UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1; ...    96   4e-19
UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa ...    89   6e-17
UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces cere...    87   2e-16
UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|R...    73   5e-12
UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;...    72   7e-12
UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3; Acti...    71   2e-11
UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;...    70   3e-11
UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2...    70   3e-11
UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobu...    69   7e-11
UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5; Gammaproteob...    68   1e-10
UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular o...    67   2e-10
UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate DeH...    66   4e-10
UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14; Thermoprote...    66   4e-10
UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=...    66   6e-10
UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Re...    66   6e-10
UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacte...    65   8e-10
UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;...    64   1e-09
UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like prot...    64   1e-09
UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter...    62   6e-09
UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28; Bacteroidet...    62   6e-09
UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD bindi...    61   2e-08
UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate deh...    60   2e-08
UniRef50_P11386 Cluster: Malate dehydrogenase; n=6; Sulfolobacea...    60   2e-08
UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2; Euryarchaeot...    60   2e-08
UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|R...    60   2e-08
UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4; Thermotog...    60   2e-08
UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate deh...    58   9e-08
UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4; Epsilonprote...    58   9e-08
UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17; Apicompl...    58   1e-07
UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4; Thermoplasma...    57   2e-07
UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2; Propionib...    57   2e-07
UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12; Bacteria...    57   2e-07
UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1; Cand...    57   3e-07
UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1; Ce...    56   4e-07
UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8; Lactoba...    56   4e-07
UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular or...    56   5e-07
UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1; Lept...    55   1e-06
UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=...    55   1e-06
UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5; Tr...    55   1e-06
UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4; Lactobaci...    54   2e-06
UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2; Pl...    54   3e-06
UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=...    54   3e-06
UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2; Gammaproteo...    54   3e-06
UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacte...    54   3e-06
UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium ...    54   3e-06
UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11; Clostrid...    53   5e-06
UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12; Firmic...    53   5e-06
UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1; ...    52   6e-06
UniRef50_O26290 Cluster: Malate dehydrogenase; n=2; Methanobacte...    52   6e-06
UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2; ...    52   8e-06
UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3; Methanomi...    52   8e-06
UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17; Bacter...    52   8e-06
UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140; Bacteri...    51   2e-05
UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasm...    51   2e-05
UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex ae...    50   3e-05
UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2; Bacteria|...    50   3e-05
UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular org...    50   4e-05
UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7; Bacteria|...    49   6e-05
UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7; Halobacteria...    48   1e-04
UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2; ...    48   1e-04
UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm...    48   1e-04
UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula...    48   1e-04
UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;...    48   1e-04
UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4; Bacteroidale...    48   2e-04
UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;...    48   2e-04
UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia ...    47   3e-04
UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metaz...    46   4e-04
UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular org...    46   5e-04
UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to ENSANGP000...    46   7e-04
UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6; Bacteria|...    46   7e-04
UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;...    46   7e-04
UniRef50_Q8ELF0 Cluster: L-lactate dehydrogenase; n=5; Bacillace...    46   7e-04
UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm...    46   7e-04
UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9; Bacilli...    46   7e-04
UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5; Bacteroidale...    45   0.001
UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondr...    45   0.001
UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:...    45   0.001
UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1; Lactobaci...    44   0.002
UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium t...    44   0.002
UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibac...    44   0.002
UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridi...    44   0.002
UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomon...    44   0.002
UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6; Mollicute...    44   0.002
UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14; Bacill...    44   0.002
UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6; Acti...    44   0.003
UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1; Ther...    44   0.003
UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12; Ca...    44   0.003
UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate dehydrog...    43   0.005
UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4; Bacteria|...    43   0.005
UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic, puta...    43   0.005
UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1; Meth...    42   0.007
UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2; Desulfovi...    42   0.012
UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Re...    41   0.020
UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;...    40   0.027
UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13; Firmic...    40   0.027
UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4; Tr...    39   0.062
UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1; Corynebac...    38   0.11 
UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizop...    38   0.11 
UniRef50_Q017A7 Cluster: Chromosome 06 contig 1, DNA sequence; n...    38   0.14 
UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia inte...    38   0.14 
UniRef50_P83778 Cluster: Malate dehydrogenase, cytoplasmic; n=1;...    33   0.18 
UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular or...    37   0.25 
UniRef50_UPI0000DB7268 Cluster: PREDICTED: similar to L-lactate ...    36   0.44 
UniRef50_UPI0000D8BD94 Cluster: UPI0000D8BD94 related cluster; n...    36   0.58 
UniRef50_UPI0001554DCB Cluster: PREDICTED: similar to Zinc finge...    36   0.76 
UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;...    36   0.76 
UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1; Asp...    36   0.76 
UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6; Trichomonadi...    35   1.0  
UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1...    35   1.3  
UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm...    35   1.3  
UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8; Chlamydiacea...    35   1.3  
UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1; Clostri...    35   1.3  
UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2; Phaeospha...    34   1.8  
UniRef50_UPI0000DD82B5 Cluster: PREDICTED: hypothetical protein;...    34   2.3  
UniRef50_Q4S3J0 Cluster: Chromosome 1 SCAF14749, whole genome sh...    33   3.1  
UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6; Plasmodi...    33   3.1  
UniRef50_Q5B0T8 Cluster: Putative uncharacterized protein; n=1; ...    33   4.1  
UniRef50_Q8NHM5 Cluster: JmjC domain-containing histone demethyl...    33   5.4  
UniRef50_UPI0000E80D01 Cluster: PREDICTED: similar to microtubul...    32   9.4  
UniRef50_UPI000023EEAF Cluster: hypothetical protein FG02077.1; ...    32   9.4  
UniRef50_Q91LF0 Cluster: ORF90; n=1; Shrimp white spot syndrome ...    32   9.4  
UniRef50_Q8XN38 Cluster: Probable hexosyltransferase; n=1; Clost...    32   9.4  
UniRef50_Q1GZK2 Cluster: Putative partition-related protein; n=1...    32   9.4  
UniRef50_Q47706 Cluster: Membrane-associated protein uidC precur...    32   9.4  

>UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial
           precursor; n=514; cellular organisms|Rep: Malate
           dehydrogenase, mitochondrial precursor - Mus musculus
           (Mouse)
          Length = 338

 Score =  164 bits (398), Expect = 1e-39
 Identities = 84/149 (56%), Positives = 105/149 (70%)
 Frame = +3

Query: 48  MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 227
           M S   +PA  A++   ++FST++Q N K         IGQPL+LLLK +PLV+RL LYD
Sbjct: 1   MLSALARPAGAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57

Query: 228 IAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNT 407
           IA  TPGVAADLSH+ T A V G+ GPE+L   +K  DVVVIP GVPR+PGMTRDDLFNT
Sbjct: 58  IAH-TPGVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT 116

Query: 408 NASIVRDIALSIAXNAPKAIVAIITNPVN 494
           NA+IV  +  + A + P+A+V II NPVN
Sbjct: 117 NATIVATLTAACAQHCPEAMVCIIANPVN 145


>UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial
           precursor; n=119; cellular organisms|Rep: Malate
           dehydrogenase, mitochondrial precursor - Homo sapiens
           (Human)
          Length = 338

 Score =  162 bits (393), Expect = 5e-39
 Identities = 81/149 (54%), Positives = 105/149 (70%)
 Frame = +3

Query: 48  MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 227
           M S   +P + A++   ++FST++Q N K         IGQPL+LLLK +PLV+RL LYD
Sbjct: 1   MLSALARPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57

Query: 228 IAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNT 407
           IA  TPGVAADLSH+ T A V G+ GPE+L   +K  DVVVIP GVPR+PGMTRDDLFNT
Sbjct: 58  IAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT 116

Query: 408 NASIVRDIALSIAXNAPKAIVAIITNPVN 494
           NA+IV  +  + A + P+A++ +I NPVN
Sbjct: 117 NATIVATLTAACAQHCPEAMICVIANPVN 145


>UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazoa
           group|Rep: Malate dehydrogenase - Aspergillus niger
          Length = 340

 Score =  146 bits (354), Expect = 3e-34
 Identities = 73/133 (54%), Positives = 98/133 (73%), Gaps = 1/133 (0%)
 Frame = +3

Query: 99  KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNT 278
           ++FS ++ +  K         IGQPL+LL+KQNPLVT LALYDI    PGVAAD+SH+NT
Sbjct: 14  RSFSASASQASKVAVLGAAGGIGQPLSLLMKQNPLVTDLALYDIRG-GPGVAADISHINT 72

Query: 279 PAKVSGHKG-PEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNA 455
            + V G++  P  L  A+K +++++IP GVPR+PGMTRDDLFNTNASIVRD+A + A  A
Sbjct: 73  NSTVKGYEPTPSGLRDALKGSEIILIPAGVPRKPGMTRDDLFNTNASIVRDLAKAAAEAA 132

Query: 456 PKAIVAIITNPVN 494
           P+A + +I+NPVN
Sbjct: 133 PEANILVISNPVN 145


>UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast
           precursor; n=41; cellular organisms|Rep: Malate
           dehydrogenase, chloroplast precursor - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 403

 Score =  143 bits (346), Expect = 3e-33
 Identities = 69/111 (62%), Positives = 86/111 (77%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDAD 341
           IGQPL+LL+K +PLV+ L LYDIA V  GVAADLSH NTP++V    GP EL+  +KD +
Sbjct: 94  IGQPLSLLIKMSPLVSTLHLYDIANVK-GVAADLSHCNTPSQVRDFTGPSELADCLKDVN 152

Query: 342 VVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           VVVIP GVPR+PGMTRDDLFN NA+IV+ +  ++A N P A + II+NPVN
Sbjct: 153 VVVIPAGVPRKPGMTRDDLFNINANIVKTLVEAVAENCPNAFIHIISNPVN 203


>UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep:
           Malate dehydrogenase - Schizosaccharomyces pombe
           (Fission yeast)
          Length = 341

 Score =  140 bits (338), Expect = 2e-32
 Identities = 71/133 (53%), Positives = 91/133 (68%), Gaps = 1/133 (0%)
 Frame = +3

Query: 99  KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNT 278
           ++FSTTS R FK         IGQPL++LLK N  V+ LAL+DI    PGVAAD+ H+NT
Sbjct: 19  RSFSTTSSRAFKVAVLGAGGGIGQPLSMLLKLNDKVSELALFDIRGA-PGVAADIGHINT 77

Query: 279 PAKVSGHKGPEE-LSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNA 455
            + V G+   ++ L  A+  ADVV+IP GVPR+PGMTRDDLF TNASIVRD+A +     
Sbjct: 78  TSNVVGYAPDDKGLEKALNGADVVIIPAGVPRKPGMTRDDLFATNASIVRDLAFAAGETC 137

Query: 456 PKAIVAIITNPVN 494
           P+A   ++TNPVN
Sbjct: 138 PEAKYLVVTNPVN 150


>UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal
           precursor; n=11; Eukaryota|Rep: Malate dehydrogenase,
           glyoxysomal precursor - Oryza sativa subsp. japonica
           (Rice)
          Length = 356

 Score =  135 bits (326), Expect = 7e-31
 Identities = 69/122 (56%), Positives = 82/122 (67%)
 Frame = +3

Query: 129 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGP 308
           FK         IGQPLALL+K NPLV+ L LYD+   TPGV AD+SH+NT A V G  G 
Sbjct: 45  FKVAILGASGGIGQPLALLMKMNPLVSVLHLYDVVN-TPGVTADISHMNTGAVVRGFLGQ 103

Query: 309 EELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNP 488
            +L  A+   D+V+IP GVPR+PGMTRDDLFN NA IVR +   IA   P AIV +I+NP
Sbjct: 104 PQLENALTGMDLVIIPAGVPRKPGMTRDDLFNINAGIVRTLCEGIAKCCPNAIVNVISNP 163

Query: 489 VN 494
           VN
Sbjct: 164 VN 165


>UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3;
           Oryza sativa|Rep: Putative uncharacterized protein -
           Oryza sativa subsp. japonica (Rice)
          Length = 405

 Score =  126 bits (304), Expect = 3e-28
 Identities = 65/115 (56%), Positives = 79/115 (68%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDAD 341
           IGQPL+LL+K +PLV+ L LYDIA V  GV ADL H NTPAKV+G  G EEL+  +   D
Sbjct: 89  IGQPLSLLVKMSPLVSALHLYDIANVD-GVTADLGHCNTPAKVAGFTGKEELAGCLAGVD 147

Query: 342 VVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSA 506
           VVVIP GVPR+PGMTRDDLF  NA IVR++  ++A +AP    A    P   + A
Sbjct: 148 VVVIPAGVPRKPGMTRDDLFGINAGIVRELVEAVADHAPAGAGARHLQPGELHRA 202


>UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Rep:
           Malate dehydrogenase - Debaryomyces hansenii (Yeast)
           (Torulaspora hansenii)
          Length = 346

 Score =  124 bits (299), Expect = 1e-27
 Identities = 64/116 (55%), Positives = 84/116 (72%), Gaps = 5/116 (4%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEE-----LSXA 326
           IGQPL+LLLK NP V+ L+L+D+     GVAADLSH+ +PAKV+G++   +     +  A
Sbjct: 13  IGQPLSLLLKLNPQVSELSLFDVVNAN-GVAADLSHICSPAKVTGYQPSSKEDRDTIQKA 71

Query: 327 IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           + ++D+VVIP GVPR+PGMTR DLFN NASI+RDI  SI    P A + II+NPVN
Sbjct: 72  LVNSDLVVIPAGVPRKPGMTRADLFNINASIIRDIVGSIGKACPNAAILIISNPVN 127


>UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida
           glabrata|Rep: Malate dehydrogenase - Candida glabrata
           (Yeast) (Torulopsis glabrata)
          Length = 373

 Score =  120 bits (288), Expect = 3e-26
 Identities = 59/111 (53%), Positives = 80/111 (72%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDAD 341
           +GQPL+LLLK N +++ LALYDI  +  GVA DLSH+NT A   G+   +++  A+K A 
Sbjct: 13  VGQPLSLLLKLNTMISELALYDIK-LAEGVATDLSHINTNADCVGYS-TDDIGQALKGAA 70

Query: 342 VVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           VVVIP GVPR PG+TRDDLF  NA IV+++  ++A + P A + II+NPVN
Sbjct: 71  VVVIPAGVPRRPGITRDDLFKLNAGIVKNLVSNVAKHCPNARLLIISNPVN 121


>UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5;
           Protostomia|Rep: Malate dehydrogenase - Drosophila
           melanogaster (Fruit fly)
          Length = 347

 Score =  118 bits (285), Expect = 6e-26
 Identities = 59/124 (47%), Positives = 79/124 (63%)
 Frame = +3

Query: 123 RNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHK 302
           R  K         IGQPL+LLLK NP ++ L+LYDI   T GV  DLSH+NT A V   +
Sbjct: 26  RGLKVAVVGSVGGIGQPLSLLLKHNPQISTLSLYDIKNTT-GVGVDLSHINTRASVCPFE 84

Query: 303 GPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIIT 482
           G   L  A+  AD+VVIP G+PR+PGM R+DL + NAS+  ++A + +   P A++A IT
Sbjct: 85  GKNGLKKAMDKADIVVIPAGLPRKPGMKREDLVDVNASVACEVAFAASEVCPGAMLAFIT 144

Query: 483 NPVN 494
           NP+N
Sbjct: 145 NPIN 148


>UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 254

 Score =  117 bits (282), Expect = 1e-25
 Identities = 52/83 (62%), Positives = 69/83 (83%)
 Frame = +3

Query: 246 GVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVR 425
           GVAADLSH++T AKV+ H+GP++L  A++   VV IP GVPR+PGMTRDDLFNTNASIV+
Sbjct: 7   GVAADLSHISTRAKVTSHQGPDDLKAALEGCSVVAIPAGVPRKPGMTRDDLFNTNASIVK 66

Query: 426 DIALSIAXNAPKAIVAIITNPVN 494
           +++ + A + PKAI+ II+NPVN
Sbjct: 67  NLSEACAKHCPKAIICIISNPVN 89


>UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 365

 Score =  117 bits (282), Expect = 1e-25
 Identities = 55/112 (49%), Positives = 79/112 (70%), Gaps = 1/112 (0%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDAD 341
           IGQPL+LLLK NP V+ LALYDI+ +T GVA DLSH+NT +   G+   E+    ++ ++
Sbjct: 13  IGQPLSLLLKLNPYVSDLALYDISDITAGVAKDLSHINTNSDSEGYNKDEDFKNLLEGSE 72

Query: 342 VVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAP-KAIVAIITNPVN 494
           +V++  G+PR+PGMTRDDLF  NA I++++ +  A  AP    + II+NPVN
Sbjct: 73  LVIVTAGIPRKPGMTRDDLFKINAKIIQNLTVKYAKFAPVHCKLLIISNPVN 124


>UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24;
           Eukaryota|Rep: Malate dehydrogenase, peroxisomal -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 343

 Score =  111 bits (268), Expect = 7e-24
 Identities = 53/111 (47%), Positives = 75/111 (67%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDAD 341
           +GQPL+LLLK +P V+ LALYDI     G+  DLSH+NT +   G+   + +   + +A 
Sbjct: 13  VGQPLSLLLKLSPYVSELALYDIR-AAEGIGKDLSHINTNSSCVGYD-KDSIENTLSNAQ 70

Query: 342 VVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           VV+IP GVPR+PG+TRDDLF  NA IV+ +  ++   AP A + +I+NPVN
Sbjct: 71  VVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVN 121


>UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3;
           Leishmania|Rep: Malate dehydrogenase, putative -
           Leishmania major
          Length = 331

 Score =  111 bits (267), Expect = 1e-23
 Identities = 61/123 (49%), Positives = 81/123 (65%), Gaps = 1/123 (0%)
 Frame = +3

Query: 129 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGHKG 305
           FK         IGQPLAL L QN  V+ LALYDI  V P GVA DLSH     KV+G+  
Sbjct: 9   FKVTVLGASGAIGQPLALALVQNKRVSELALYDI--VQPRGVAVDLSHFPRKVKVTGYP- 65

Query: 306 PEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITN 485
            + +  A+  AD+V++  G+PR PGMT DDLFNTNA  V +++ ++A  APK+++AII+N
Sbjct: 66  TKWIHKALDGADLVLMSAGMPRRPGMTHDDLFNTNALTVNELSAAVARYAPKSVLAIISN 125

Query: 486 PVN 494
           P+N
Sbjct: 126 PLN 128


>UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|Rep:
           Malate dehydrogenase - Drosophila melanogaster (Fruit
           fly)
          Length = 349

 Score =  106 bits (255), Expect = 3e-22
 Identities = 54/124 (43%), Positives = 77/124 (62%)
 Frame = +3

Query: 123 RNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHK 302
           R  K         IGQPL+LLL++ P +  LAL+D++ +  G+A DLSH++   KV G  
Sbjct: 21  RTLKVAVVGAGGGIGQPLSLLLRRCPGIDELALHDLSEMK-GIATDLSHISQTGKVIGFT 79

Query: 303 GPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIIT 482
           G +EL  A+  ADVVV+  G+PR PGM RD L   N ++   +A +I+  +P+A +A IT
Sbjct: 80  GEKELESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKVATAISNASPRAHLAFIT 139

Query: 483 NPVN 494
           NPVN
Sbjct: 140 NPVN 143


>UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep:
           ADL164Cp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 381

 Score =  104 bits (249), Expect = 1e-21
 Identities = 65/127 (51%), Positives = 77/127 (60%), Gaps = 16/127 (12%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVT--------RLALYDIAP-VTPGVAADLSHVNTPAKVSGH----- 299
           IGQPL+LLLK               LALYD+A     GVAADLSHVNTP +VS H     
Sbjct: 35  IGQPLSLLLKTQLAQVLGDANASLELALYDVAADALAGVAADLSHVNTPVEVSHHVPSSR 94

Query: 300 KGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSI--AXNAPKAIVA 473
           +  E L  A+  A VVVIP GVPR+PGMTRDDL N NA I++ +A  I  A +  K  V 
Sbjct: 95  EDEEALREALTGASVVVIPAGVPRKPGMTRDDLININAGIIKTLAKGIAGACDLEKVFVL 154

Query: 474 IITNPVN 494
           +I+NPVN
Sbjct: 155 VISNPVN 161


>UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9;
           Trypanosomatidae|Rep: Glycosomal malate dehydrogenase -
           Leishmania major
          Length = 322

 Score =  102 bits (244), Expect = 6e-21
 Identities = 59/119 (49%), Positives = 76/119 (63%), Gaps = 8/119 (6%)
 Frame = +3

Query: 162 IGQPLALLL-KQNPLVTRLALYDIAPVTPGVAADLSHV-NTPAKVS------GHKGPEEL 317
           IGQ L+LLL +Q P  + L+L+D+     GVAADLSHV N   +V       GHK    L
Sbjct: 13  IGQSLSLLLVRQLPYGSTLSLFDVVGAA-GVAADLSHVDNAGVQVKFAEGKIGHKRDPAL 71

Query: 318 SXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           +   K  DV V+  GVPR+PGMTRDDLF  NA I+ D+ L+ A ++PKA+  I+TNPVN
Sbjct: 72  AELAKGVDVFVMVAGVPRKPGMTRDDLFKINAGIILDLVLTCASSSPKAVFCIVTNPVN 130


>UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;
           Saccharomycetaceae|Rep: Malate dehydrogenase,
           cytoplasmic - Saccharomyces cerevisiae (Baker's yeast)
          Length = 377

 Score = 99.5 bits (237), Expect = 4e-20
 Identities = 63/136 (46%), Positives = 80/136 (58%), Gaps = 14/136 (10%)
 Frame = +3

Query: 162 IGQPLALLLK---------QNPLVTR--LALYDI-APVTPGVAADLSHVNTPAKVSGHKG 305
           IGQ L+LLLK          N  VT   LALYD+      GV ADLSH++TP  VS H  
Sbjct: 25  IGQSLSLLLKAQLQYQLKESNRSVTHIHLALYDVNQEAINGVTADLSHIDTPISVSSHSP 84

Query: 306 PEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIA--XNAPKAIVAII 479
              +   + +A +VVIP GVPR+PGMTRDDLFN NA I+  +  SIA   +  K  V +I
Sbjct: 85  AGGIENCLHNASIVVIPAGVPRKPGMTRDDLFNVNAGIISQLGDSIAECCDLSKVFVLVI 144

Query: 480 TNPVNFYSALLPLKCS 527
           +NPVN   +L+P+  S
Sbjct: 145 SNPVN---SLVPVMVS 157


>UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 387

 Score = 96.3 bits (229), Expect = 4e-19
 Identities = 59/125 (47%), Positives = 79/125 (63%), Gaps = 6/125 (4%)
 Frame = +3

Query: 162 IGQPLALLLK-----QNPLVTRLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPEELSX 323
           IGQ L+LLL+      N     LAL+D+   V  GV ADLSHVNT  K+S H   + L  
Sbjct: 52  IGQSLSLLLRTSLQNNNDNQLHLALFDVNMKVLNGVHADLSHVNTNMKLSLH---DNLRD 108

Query: 324 AIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYS 503
           ++ D+++V+IP GVPR+PGMTRDDLFN NA I++ IA  +        V +I+NPVN   
Sbjct: 109 SLVDSNLVIIPAGVPRKPGMTRDDLFNINAGIIKGIAQELNTIDSTPFVLLISNPVN--- 165

Query: 504 ALLPL 518
           +LLP+
Sbjct: 166 SLLPV 170


>UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa
           triquetra|Rep: Malate dehydrogenase - Heterocapsa
           triquetra (Dinoflagellate)
          Length = 402

 Score = 89.0 bits (211), Expect = 6e-17
 Identities = 51/131 (38%), Positives = 70/131 (53%), Gaps = 9/131 (6%)
 Frame = +3

Query: 129 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI-APVTP--GVAADLSHVNTPAKVSGH 299
           FK         IGQPL LL+  +P V  L ++D+   + P  GVA DL H+   A V G+
Sbjct: 81  FKVCVCGGAGGIGQPLCLLMAMDPNVKELCVFDLNVAMVPAQGVATDLGHLEKKAAVKGY 140

Query: 300 ------KGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPK 461
                 K  + L   +    +V+IP G+PR+PG TRDDLF  NA I + I  + A   P 
Sbjct: 141 VMEVGQKPVDNLEECLTGCHLVLIPAGMPRKPGQTRDDLFKINADIAKGIVEACAKYCPD 200

Query: 462 AIVAIITNPVN 494
           A++ +I NPVN
Sbjct: 201 AMLGMIVNPVN 211


>UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces
           cerevisiae YOL126c MDH2 malate dehydrogenase; n=1;
           Kluyveromyces lactis|Rep: Similar to sp|P22133
           Saccharomyces cerevisiae YOL126c MDH2 malate
           dehydrogenase - Kluyveromyces lactis (Yeast) (Candida
           sphaerica)
          Length = 404

 Score = 87.4 bits (207), Expect = 2e-16
 Identities = 55/132 (41%), Positives = 75/132 (56%), Gaps = 15/132 (11%)
 Frame = +3

Query: 162 IGQPLALLLKQN-----PLVT----RLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPE 311
           IGQ L+LLLK N     P  T    RL+LYD+      G AADLSH++TP   + H   +
Sbjct: 58  IGQSLSLLLKSNAGFLLPHETSTHIRLSLYDVNKDAIVGTAADLSHIDTPITTTAHYPDD 117

Query: 312 E---LSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIA--XNAPKAIVAI 476
               +   + +A VV+IP GVPR+PGM+RDDL   NA I++ +   IA   +  K  V +
Sbjct: 118 SNGGIGQCLSNASVVIIPAGVPRKPGMSRDDLIGVNAKIIKSLGEDIAKYCDLNKVHVLV 177

Query: 477 ITNPVNFYSALL 512
           I+NP+N    LL
Sbjct: 178 ISNPINSLVPLL 189


>UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|Rep:
           Malate dehydrogenase - Plasmodium falciparum
          Length = 313

 Score = 72.5 bits (170), Expect = 5e-12
 Identities = 39/96 (40%), Positives = 58/96 (60%), Gaps = 2/96 (2%)
 Frame = +3

Query: 213 LALYDIAPVTP-GVAADLSHVNTPAKVSGH-KGPEELSXAIKDADVVVIPXGVPREPGMT 386
           L LYD+ P  P G A DL H +T   V+ +  G  ++   IKDAD++VI  GV R+ GMT
Sbjct: 28  LILYDVVPGIPQGKALDLKHFSTILGVNRNILGTNQIED-IKDADIIVITAGVQRKEGMT 86

Query: 387 RDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           R+DL   N  I++ +A S+  +  KA V  ++NP++
Sbjct: 87  REDLIGVNGKIMKSVAESVKLHCSKAFVICVSNPLD 122


>UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG7998-PA - Tribolium castaneum
          Length = 376

 Score = 72.1 bits (169), Expect = 7e-12
 Identities = 38/110 (34%), Positives = 65/110 (59%)
 Frame = +3

Query: 165 GQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADV 344
           G+ ++L+LKQ+P +  L LYD   +  G A DL++V+T  +V+   G +++  A+  +++
Sbjct: 41  GKSVSLMLKQSPFIDELCLYDTQSLE-GFANDLNYVDTKCRVTSFFGNKDIQKALTKSNI 99

Query: 345 VVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           +V+              LF+ NA IV+D+A SIA  +PK+ VAI   P+N
Sbjct: 100 IVVLSCCHAAEPTNYASLFDRNAPIVKDLATSIAKFSPKSTVAIGVEPIN 149


>UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3;
           Actinomycetales|Rep: Lactate/malate dehydrogenase -
           Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
          Length = 330

 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 33/64 (51%), Positives = 46/64 (71%)
 Frame = +3

Query: 327 IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSA 506
           I DA +V+I  GVPR+PGM+R DL  TNA IVR +A +IA  AP A+V +++NP++  +A
Sbjct: 85  IADASIVIITAGVPRKPGMSRMDLLETNARIVRGVAENIAKYAPSAVVIVVSNPLDEMTA 144

Query: 507 LLPL 518
           L  L
Sbjct: 145 LTQL 148


>UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;
           n=2; Apis mellifera|Rep: PREDICTED: similar to CG7998-PA
           - Apis mellifera
          Length = 333

 Score = 70.1 bits (164), Expect = 3e-11
 Identities = 42/119 (35%), Positives = 72/119 (60%), Gaps = 1/119 (0%)
 Frame = +3

Query: 165 GQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEE-LSXAIKDAD 341
           G  L+L LKQ+PL+  LA++D    T G+A DL++++T  KVS    PE+ L   ++ A 
Sbjct: 13  GNCLSLFLKQSPLIDELAIFDNNSSTYGLALDLNYIDTKCKVSTCNHPEKCLEETLQGAK 72

Query: 342 VVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSALLPL 518
           +V+I   V        +++  +NA I+ D+  +I   +P+A++AI+ NP+N   +L+PL
Sbjct: 73  IVMI---VTDRTSNESNEVLKSNAIILSDLLPNIIKFSPQAMLAIVMNPIN---SLIPL 125


>UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2;
           Toxoplasma gondii|Rep: Mitochondrial
           malate-dehydrogenase - Toxoplasma gondii
          Length = 470

 Score = 70.1 bits (164), Expect = 3e-11
 Identities = 45/123 (36%), Positives = 65/123 (52%), Gaps = 2/123 (1%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGH-KGPEELSXAIKD 335
           IG  LALL     L   + ++D+    P G   DL  +   + V    +G  + S  +KD
Sbjct: 168 IGATLALLSAVKELGD-VVMFDVVQDLPQGKCLDLYQLTPISGVDVRFEGSNDYS-VLKD 225

Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSALLP 515
           ADV+++  GVPR+PGM+RDDL   NA I+  +  +I    P A V  ITNP++    +L 
Sbjct: 226 ADVIIVTAGVPRKPGMSRDDLLAINAKIMGQVGEAIKQYCPNAFVICITNPLDVMVYILR 285

Query: 516 LKC 524
            KC
Sbjct: 286 EKC 288


>UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobus
           fulgidus|Rep: Malate dehydrogenase - Archaeoglobus
           fulgidus
          Length = 294

 Score = 68.9 bits (161), Expect = 7e-11
 Identities = 41/119 (34%), Positives = 67/119 (56%), Gaps = 2/119 (1%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVNTPA-KVSGHKGPEELSXAIKD 335
           +G   A     N  V  +AL DIA  +  G A DL+H      K     G  + S  +K 
Sbjct: 11  VGSTSAFTCLLNLDVDEIALVDIAEDLAVGEAMDLAHAAAGIDKYPKIVGGADYSL-LKG 69

Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSALL 512
           ++++V+  G+ R+PGMTR DL + NA I++DIA  I  NAP++ + ++TNP++  + ++
Sbjct: 70  SEIIVVTAGLARKPGMTRLDLAHKNAGIIKDIAKKIVENAPESKILVVTNPMDVMTYIM 128


>UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5;
           Gammaproteobacteria|Rep: Malate dehydrogenase -
           Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
          Length = 311

 Score = 68.1 bits (159), Expect = 1e-10
 Identities = 42/116 (36%), Positives = 64/116 (55%), Gaps = 5/116 (4%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSH----VNTPAKVSGHKGPEELSXA 326
           +G+  A  L +N L   L L D    V  G A D+       +  A+V+G    E     
Sbjct: 14  VGEATAQFLVKNELCRELVLLDAQEGVAQGAALDIQQSAPLFDFDARVTGSTNYE----L 69

Query: 327 IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           I D+D+VVI  G PR+PGM+R D+ ++N  I+ DI  ++   AP+++V I+TNPV+
Sbjct: 70  IADSDLVVITAGKPRKPGMSRSDVLDSNLPIITDIMNNVMRFAPQSLVMIVTNPVD 125


>UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular
           organisms|Rep: Malate dehydrogenase - Silicibacter
           pomeroyi
          Length = 320

 Score = 67.3 bits (157), Expect = 2e-10
 Identities = 43/113 (38%), Positives = 60/113 (53%), Gaps = 2/113 (1%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGH-KGPEELSXAIKD 335
           IG  LA L+    L   + L+DIA  TP G A D++            KG +  +  I  
Sbjct: 14  IGGTLAHLVALKELGD-VVLFDIAEGTPEGKALDIAESGPSEGFDAKLKGTQSYAD-IAG 71

Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           ADV ++  GVPR+PGM+RDDL   N  +++ +   I  NAP A V  ITNP++
Sbjct: 72  ADVCIVTAGVPRKPGMSRDDLLGINLKVMKSVGEGIRDNAPDAFVICITNPLD 124


>UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate
           DeHydrogenase family member (mdh-1); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Malate
           DeHydrogenase family member (mdh-1) - Tribolium
           castaneum
          Length = 374

 Score = 66.5 bits (155), Expect = 4e-10
 Identities = 43/119 (36%), Positives = 64/119 (53%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDAD 341
           +G  LALLLKQN  +  L L+D    T   A DL+ ++T  K+      + L  AI  A 
Sbjct: 40  VGSNLALLLKQNLDIYELRLFDEENNTNAFACDLNEIDTRTKLKSFSC-KSLKNAIVGAH 98

Query: 342 VVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSALLPL 518
           VV+   G   +PG ++ +LF+ N   VR++A+ +A   P+AI  I   PV    AL+P+
Sbjct: 99  VVISTGGCQEKPGSSQRELFDKNLDNVRNVAMFLAEFNPEAIYCIAKPPV---EALVPM 154


>UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14;
           Thermoprotei|Rep: Malate dehydrogenase - Pyrobaculum
           aerophilum
          Length = 309

 Score = 66.5 bits (155), Expect = 4e-10
 Identities = 37/113 (32%), Positives = 64/113 (56%), Gaps = 2/113 (1%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVS-GHKGPEELSXAIKD 335
           +G   A+++    L  ++ L DI    P G A D++H+++   +   + G  E    I+ 
Sbjct: 10  VGTAAAVIMGLMKLDNKILLIDIVKGLPQGEALDMNHMSSILGLDVEYVGSNEYKD-IEG 68

Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           +D++++  G+PR+PGMTR+ L   NA IV +I   I   AP +IV + TNP++
Sbjct: 69  SDLIIVTAGLPRKPGMTREQLLEANAKIVAEIGREIKKYAPDSIVILTTNPLD 121


>UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=1;
           Sulfurovum sp. NBC37-1|Rep: Malate dehydrogenase,
           NAD-dependent - Sulfurovum sp. (strain NBC37-1)
          Length = 320

 Score = 65.7 bits (153), Expect = 6e-10
 Identities = 44/118 (37%), Positives = 63/118 (53%), Gaps = 8/118 (6%)
 Frame = +3

Query: 165 GQPLALLLKQNPLVTRLAL----YDIAPVTPGVAADLSHVNTPAK----VSGHKGPEELS 320
           G  +A +L  N     + L    YD+A    G A D+S     A+    V   KGPE++ 
Sbjct: 16  GSTVAFILAMNGSCHHVMLRGRNYDVAK---GKALDMSQAANAARQHTIVKAAKGPEDM- 71

Query: 321 XAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
              + +DVV+I  G PR PGM+RDDL   NA IV+  +  I   AP AIV +++NP++
Sbjct: 72  ---EGSDVVIITAGAPRTPGMSRDDLLFKNADIVKCYSREIKEYAPDAIVIVVSNPLD 126


>UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Rep:
           Malate dehydrogenase - Brucella melitensis
          Length = 320

 Score = 65.7 bits (153), Expect = 6e-10
 Identities = 38/97 (39%), Positives = 57/97 (58%), Gaps = 3/97 (3%)
 Frame = +3

Query: 213 LALYDIAPVTP-GVAADLSHVNTPAKVSGHK--GPEELSXAIKDADVVVIPXGVPREPGM 383
           + L+DIA  TP G   D++  ++P      K  G  + + AI+ ADVV++  GVPR+PGM
Sbjct: 30  VVLFDIAEGTPQGKGLDIAE-SSPVDGFDAKFTGANDYA-AIEGADVVIVTAGVPRKPGM 87

Query: 384 TRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           +RDDL   N  ++  +   I   AP+A V  ITNP++
Sbjct: 88  SRDDLLGINLKVMEQVGAGIKKYAPEAFVICITNPLD 124


>UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacter
           hominis ATCC BAA-381|Rep: Malate dehydrogenase -
           Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 /
           NCTC 13146 /CH001A)
          Length = 297

 Score = 65.3 bits (152), Expect = 8e-10
 Identities = 40/102 (39%), Positives = 61/102 (59%), Gaps = 5/102 (4%)
 Frame = +3

Query: 204 VTRLALYDI-APVTPGVAADLSHV----NTPAKVSGHKGPEELSXAIKDADVVVIPXGVP 368
           ++++AL DI   +    A DLSH+    N   ++SG    E L   +K++D+VVI  G  
Sbjct: 26  ISQIALIDIFGDLAKARALDLSHLASVYNKKTEISG-SSDETL---LKNSDIVVITAGKT 81

Query: 369 REPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           R+ G +R DL N NA I+   A ++A  AP+AI+ +ITNPV+
Sbjct: 82  RQAGQSRADLLNDNAKIISSCAKNVAKYAPEAIIILITNPVD 123


>UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;
           Ignicoccus hospitalis KIN4/I|Rep: malate dehydrogenase
           (NAD) - Ignicoccus hospitalis KIN4/I
          Length = 311

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 38/118 (32%), Positives = 58/118 (49%), Gaps = 1/118 (0%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
           +G   A  +   P V R+ L D  P ++ GV  D+ H     + S      +    +++A
Sbjct: 16  VGATFAYTMAIVPGVARMVLVDAVPGLSKGVMEDIKHAAAVFRRSIQVEAYDDVSKVENA 75

Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSALL 512
           D +VI  G PR+  M+R DL   NA I+RDI   +    P A   +ITNPV+  + +L
Sbjct: 76  DAIVITAGKPRKADMSRRDLAKVNAQIIRDIGDKLRDRNPGAFYMVITNPVDVMTMIL 133


>UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like
           protein; n=1; Methylibium petroleiphilum PM1|Rep:
           Malate/lactate dehydrogenases-like protein - Methylibium
           petroleiphilum (strain PM1)
          Length = 432

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 36/111 (32%), Positives = 59/111 (53%), Gaps = 1/111 (0%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
           +G   AL L ++ L + +AL D+ P +  G+A D+ H       S      +   A+  A
Sbjct: 134 VGAMTALRLAESDLFSEVALVDVVPGLAAGLALDMWHGAGLYGFSTRLSGSDDLVALAGA 193

Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPV 491
           + +VI  G PR+PGM+R DL   NA I+  +   I  +AP + + I++NP+
Sbjct: 194 EYIVITAGKPRQPGMSRTDLTVVNAEIMTSVCRGIRTHAPNSTLVIVSNPL 244


>UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter
           hepaticus|Rep: Malate dehydrogenase - Helicobacter
           hepaticus
          Length = 315

 Score = 62.5 bits (145), Expect = 6e-09
 Identities = 37/117 (31%), Positives = 67/117 (57%), Gaps = 6/117 (5%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALY--DIAPVTPGVAADLSHV----NTPAKVSGHKGPEELSX 323
           +G  +A L     +   + L+  DI P   GV  D+S      + P  + G    EE++ 
Sbjct: 14  VGSHIAFLGAMRHIAKEILLFSNDI-PRCKGVGLDISQAAAIFDIPILIKGCNSYEEIA- 71

Query: 324 AIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
              +++VV+I  G PR P MTR+DL   NASI+++I+ ++A  AP++++ +++NP++
Sbjct: 72  ---ESEVVIITAGFPRTPNMTRNDLLLKNASIIQEISSNVARIAPQSLLIVVSNPLD 125


>UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28;
           Bacteroidetes|Rep: Malate dehydrogenase - Bacteroides
           fragilis
          Length = 313

 Score = 62.5 bits (145), Expect = 6e-09
 Identities = 25/54 (46%), Positives = 41/54 (75%)
 Frame = +3

Query: 333 DADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           ++DVVVI  G+PR+PGMTR++L   NA IV+ +A ++   +P AI+ +I+NP++
Sbjct: 71  NSDVVVITSGIPRKPGMTREELIGVNAGIVKSVAENLLKYSPNAIIVVISNPMD 124


>UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD binding
           domain protein; n=2; Campylobacter|Rep: Lactate/malate
           dehydrogenase, NAD binding domain protein -
           Campylobacter curvus 525.92
          Length = 297

 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 38/113 (33%), Positives = 59/113 (52%), Gaps = 2/113 (1%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTP-AKVSGHKGPEELSXAIKD 335
           +G  +A  L    +   +AL DI   V    A D++             G ++ +  I+ 
Sbjct: 11  VGASIAYALAMRGVCDEIALVDIFGDVARAKAIDIAQAGCVFCGCLSTAGGDDFAL-IEA 69

Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           +D+VV+  G PR+ G TR+DL   NA +V+  A +IA  AP AIV I+TNP++
Sbjct: 70  SDIVVVTAGSPRKEGQTREDLLLKNAQVVKQTAQNIAKFAPNAIVIIVTNPLD 122


>UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate
           dehydrogenase, mitochondrial precursor; n=1; Canis lupus
           familiaris|Rep: PREDICTED: similar to Malate
           dehydrogenase, mitochondrial precursor - Canis
           familiaris
          Length = 245

 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 25/43 (58%), Positives = 34/43 (79%)
 Frame = +3

Query: 366 PREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           PR+PGMTRDDLFNTNAS+V     + A + P+A++ +I+NPVN
Sbjct: 61  PRKPGMTRDDLFNTNASVVATPTAACAQHCPEAMICVISNPVN 103


>UniRef50_P11386 Cluster: Malate dehydrogenase; n=6;
           Sulfolobaceae|Rep: Malate dehydrogenase - Sulfolobus
           acidocaldarius
          Length = 306

 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 36/117 (30%), Positives = 56/117 (47%), Gaps = 1/117 (0%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTPG-VAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
           +GQ +A     N     + LYD+ P  P     ++ H     +V            I  A
Sbjct: 12  VGQTIAYNTIVNGYADEVMLYDVVPELPEKFEHEIRHALAALRVKTELLSTNNIDDISGA 71

Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSAL 509
           D+VVI  G PR+PGM+R DLF  NA I+ D+A  +      A+  ++ NPV+  +++
Sbjct: 72  DIVVITAGKPRKPGMSRRDLFIDNAKIMIDLAKKLPKKNKGAMYIMVANPVDMMASV 128


>UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2;
           Euryarchaeota|Rep: Malate dehydrogenase - Methanopyrus
           kandleri
          Length = 317

 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 26/54 (48%), Positives = 38/54 (70%)
 Frame = +3

Query: 333 DADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           DADV+V+  G+PR+PG TR DL   NA+I++     +A   P+AIV ++TNPV+
Sbjct: 73  DADVIVMTAGIPRKPGQTRLDLTKDNAAIIKKYLEGVAEENPEAIVLVVTNPVD 126


>UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|Rep:
           Malate dehydrogenase 1 - Aquifex aeolicus
          Length = 335

 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 34/80 (42%), Positives = 49/80 (61%), Gaps = 2/80 (2%)
 Frame = +3

Query: 261 LSHVNTPAKVSGHK-GPE-ELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIA 434
           L+ ++  A+V G+   PE E    ++ +D+VVI  G PR PGM+R+DL   N  I+  IA
Sbjct: 59  LAAMDIDARVEGYTVTPEGEGYEPLEGSDIVVITAGFPRRPGMSREDLLEANIRIISVIA 118

Query: 435 LSIAXNAPKAIVAIITNPVN 494
             I   AP AIV ++TNPV+
Sbjct: 119 DRIKRYAPDAIVIVVTNPVD 138


>UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4;
           Thermotogaceae|Rep: L-lactate dehydrogenase - Thermotoga
           maritima
          Length = 319

 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 36/112 (32%), Positives = 59/112 (52%), Gaps = 1/112 (0%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
           +G   A  L        + L D+      G A DL H  TP     +    + +  +K +
Sbjct: 11  VGSSTAFALLMKGFAREMVLIDVDKKRAEGDALDLIH-GTPFTRRANIYAGDYAD-LKGS 68

Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           DVV++  GVP++PG TR  L   NA ++++IA +++  AP +IV ++TNPV+
Sbjct: 69  DVVIVAAGVPQKPGETRLQLLGRNARVMKEIARNVSKYAPDSIVIVVTNPVD 120


>UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate
           dehydrogenase, mitochondrial precursor; n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Malate
           dehydrogenase, mitochondrial precursor - Tribolium
           castaneum
          Length = 349

 Score = 58.4 bits (135), Expect = 9e-08
 Identities = 35/133 (26%), Positives = 66/133 (49%)
 Frame = +3

Query: 96  AKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVN 275
           +++F +  Q++ +         +GQ LA L+KQNP ++ L L   + V   +A D +H +
Sbjct: 11  SRHFCSKPQKHVQVCILGADTLLGQSLAFLIKQNPAISGLHLQGTSKV-ESMALDFNHFD 69

Query: 276 TPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNA 455
           T  +V  +   + +S ++K AD+VV+         M+   L       V  +A + A  A
Sbjct: 70  TRCRVHSYYDMDSVSKSVKCADIVVMLGLNTSTSKMSIPKLVMAEGVRVAKLAETCAKYA 129

Query: 456 PKAIVAIITNPVN 494
           PKA++ +   P++
Sbjct: 130 PKAVIVVAVTPIS 142


>UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4;
           Epsilonproteobacteria|Rep: Malate dehydrogenase -
           Wolinella succinogenes
          Length = 314

 Score = 58.4 bits (135), Expect = 9e-08
 Identities = 29/112 (25%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
           +G  +A +L    +   + + D+   T  G+A D+ H  +  K             ++  
Sbjct: 9   VGSTVAFILATQGICQEIIIKDLNLDTARGIALDMGHAASATKTHTIVRVANEPSDLRGC 68

Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           DVVV   G PR+PGM+RDDL   NA ++R +   +     ++++ +++NP++
Sbjct: 69  DVVVFCAGSPRQPGMSRDDLLLANAKVIRTVLSEVKPYIQESVLVMVSNPLD 120


>UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17;
           Apicomplexa|Rep: L-lactate dehydrogenase - Plasmodium
           falciparum (isolate CDC / Honduras)
          Length = 316

 Score = 58.0 bits (134), Expect = 1e-07
 Identities = 46/127 (36%), Positives = 63/127 (49%), Gaps = 10/127 (7%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPA----KVSGHKGPEELSXA 326
           IG  +A L+ Q  L   + L+DI    P G A D SH N  A    KVSG    ++L+ A
Sbjct: 15  IGGVMATLIVQKNLGD-VVLFDIVKNMPHGKALDTSHTNVMAYSNCKVSGSNTYDDLAGA 73

Query: 327 IKDADVVVIPXGVPREPGMT-----RDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPV 491
               DVV++  G  + PG +     RDDL   N  I+ +I   I  N P A + ++TNPV
Sbjct: 74  ----DVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKKNCPNAFIIVVTNPV 129

Query: 492 NFYSALL 512
           +    LL
Sbjct: 130 DVMVQLL 136


>UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4;
           Thermoplasmatales|Rep: Malate dehydrogenase -
           Thermoplasma volcanium
          Length = 325

 Score = 57.2 bits (132), Expect = 2e-07
 Identities = 21/62 (33%), Positives = 43/62 (69%)
 Frame = +3

Query: 327 IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSA 506
           ++ +DV+V+  G+ R+PGM+R+DLF+ N  I+ D++ +I   +P +I+ +++NP +  + 
Sbjct: 74  MEGSDVIVVTAGMARKPGMSREDLFDKNVEIIADVSKNIKKYSPDSIIVVVSNPADIMAY 133

Query: 507 LL 512
            L
Sbjct: 134 AL 135


>UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2;
           Propionibacterium acnes|Rep: L-lactate dehydrogenase -
           Propionibacterium acnes
          Length = 319

 Score = 57.2 bits (132), Expect = 2e-07
 Identities = 35/95 (36%), Positives = 51/95 (53%), Gaps = 3/95 (3%)
 Frame = +3

Query: 213 LALYDIAP-VTPGVAADLSHVN--TPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGM 383
           ++LYDIA        ADL+H    TPA V G     + +    D+DVV I  G  ++PG 
Sbjct: 38  VSLYDIAKDKVEAEVADLAHGTQFTPASVMGGADVHDTA----DSDVVFITAGARQKPGQ 93

Query: 384 TRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNP 488
           TR DL   NA+I+R +   +   +P A+  ++TNP
Sbjct: 94  TRLDLAGVNANILRSLMPQLVEQSPNALFVLVTNP 128


>UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12;
           Bacteria|Rep: L-lactate dehydrogenase - Clostridium
           tetani
          Length = 316

 Score = 57.2 bits (132), Expect = 2e-07
 Identities = 38/113 (33%), Positives = 57/113 (50%), Gaps = 2/113 (1%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSH-VNTPAKVSGHKGPEELSXAIKD 335
           +G   A  L    L + + + DI      G A DLSH V+    V    G  E +   KD
Sbjct: 16  VGSTTAYALMMEGLASEIVIVDINKEKAKGEAMDLSHGVSFVKPVDIIAGDYEDT---KD 72

Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           +D+V+I  G   +PG TR DL N N  I + I   +   +PK+I+ +++NPV+
Sbjct: 73  SDIVIITAGAGPKPGETRLDLINKNYEIFKGIVPEVVKYSPKSILLVVSNPVD 125


>UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1;
           Candidatus Nitrosopumilus maritimus SCM1|Rep:
           Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
           maritimus SCM1
          Length = 304

 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 35/113 (30%), Positives = 60/113 (53%), Gaps = 2/113 (1%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGH-KGPEELSXAIKD 335
           +G   AL      L  ++ L D+A   P G A D++H+ +   +    KG       +K 
Sbjct: 10  VGGDAALFSALKRLDDQILLLDVAEGLPQGEAMDINHMLSEQGIDVEVKGSNNFED-MKG 68

Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           +++VV+  G  R+PGMTR DL   NASIV+ +  ++   A  +++  +TNP++
Sbjct: 69  SNIVVVVAGSGRKPGMTRMDLLKINASIVKSVVENVKKYADDSMIIPVTNPLD 121


>UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1;
           Cenarchaeum symbiosum|Rep: Malate/L-lactate
           dehydrogenase - Cenarchaeum symbiosum
          Length = 302

 Score = 56.4 bits (130), Expect = 4e-07
 Identities = 33/113 (29%), Positives = 59/113 (52%), Gaps = 2/113 (1%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGH-KGPEELSXAIKD 335
           +G   A+      L + + L DI    P G A D++H+     +    +G  + S  ++ 
Sbjct: 10  VGGDAAMFCALRRLDSEILLLDIVEGLPQGEAMDINHMLAEQGIDTEVRGSNDYSD-MEG 68

Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           +D+VV+  G  R+PGMTR DL   NA IV+ +   +  +A  +++  +TNP++
Sbjct: 69  SDIVVVVAGAGRKPGMTRMDLLKINAGIVKGVVEKVKEHAKDSMIIPVTNPLD 121


>UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8;
           Lactobacillus|Rep: L-lactate dehydrogenase 2 -
           Lactobacillus plantarum
          Length = 309

 Score = 56.4 bits (130), Expect = 4e-07
 Identities = 38/118 (32%), Positives = 56/118 (47%), Gaps = 2/118 (1%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSHVNTPAKVSG-HKGPEELSXAIKD 335
           +G   A  L QN  +  L + D+      G   DL  V      +  H G  E + A +D
Sbjct: 16  VGSSFAFSLVQNCALDELVIVDLVKTHAEGDVKDLEDVAAFTNATNIHTG--EYADA-RD 72

Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSAL 509
           AD+VVI  GVPR+PG +R DL N N  I+  I   +  +       I +NPV+  +++
Sbjct: 73  ADIVVITAGVPRKPGESRLDLINRNTKILESIVKPVVASGFNGCFVISSNPVDILTSM 130


>UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular
           organisms|Rep: Malate dehydrogenase - Gloeobacter
           violaceus
          Length = 325

 Score = 56.0 bits (129), Expect = 5e-07
 Identities = 40/119 (33%), Positives = 59/119 (49%), Gaps = 5/119 (4%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGHK----GPEELSXA 326
           +G  LA  L Q   V  + L DI    P G+  DL        V GH     G  + +  
Sbjct: 19  VGSALAQRLIQGN-VADVVLLDIVEGRPQGITLDLLEA---CGVEGHTCRITGTNDYAQT 74

Query: 327 IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYS 503
              +DV+V+  G  R+PGM+RDDL  TN  IV ++      ++P+A V ++TNP++  S
Sbjct: 75  A-GSDVLVVAAGFARQPGMSRDDLLLTNTRIVFEVTQKAVAHSPEATVVVVTNPLDAMS 132


>UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1;
           Leptospirillum sp. Group II UBA|Rep: Malate/lactate
           dehydrogenase - Leptospirillum sp. Group II UBA
          Length = 320

 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 23/62 (37%), Positives = 42/62 (67%)
 Frame = +3

Query: 327 IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSA 506
           I+ + VVV+  G  R+PGM+R+DL + N  I+ ++A  I  +AP ++V ++TNP++  + 
Sbjct: 72  IEGSSVVVVTAGFSRKPGMSREDLLHKNGDIMIEVAEKIRKHAPDSVVIMVTNPMDLMAY 131

Query: 507 LL 512
           +L
Sbjct: 132 IL 133


>UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=1;
           Entamoeba histolytica|Rep: NAD-specific malate
           dehydrogenase 2 - Entamoeba histolytica
          Length = 329

 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 2/96 (2%)
 Frame = +3

Query: 213 LALYDIAPVT-PGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTR 389
           L LYD+  +   G++ +L+    P K+ G     E++ A  + DV +I  GVPR+PGM R
Sbjct: 47  LHLYDLNDMALKGLSMELTDCCLP-KLKGIISTTEIALAFSNVDVAIIVAGVPRKPGMQR 105

Query: 390 DDLFNTNASIVRDIALSIAXNAPKAI-VAIITNPVN 494
            DL N N  ++     ++   + K + V ++ NP N
Sbjct: 106 SDLINVNKKVMEMNGKALGTYSNKDVRVVVVANPAN 141


>UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5;
           Trypanosomatidae|Rep: Malate dehydrogenase, putative -
           Leishmania major
          Length = 342

 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 39/134 (29%), Positives = 64/134 (47%), Gaps = 5/134 (3%)
 Frame = +3

Query: 108 STTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAP----VTPGVAADLSHVN 275
           S T+ +  K         +GQPL+LLLK NP V  L   + A        G+AADLSH++
Sbjct: 8   SLTALKKGKVVLFGCSNAVGQPLSLLLKMNPHVEELVCCNTAADDDVPGSGIAADLSHID 67

Query: 276 TPAKVSGHKGPEELSXAIKDADVVVIPXGVPRE-PGMTRDDLFNTNASIVRDIALSIAXN 452
           T  KV       +    ++DA ++++  G   +     RD      A  +R +  ++A +
Sbjct: 68  TLPKVHYATDEGQWPALLRDAQLILVCFGSSFDLLREDRDIALKAAAPTMRRVMAAVASS 127

Query: 453 APKAIVAIITNPVN 494
                VA++++PVN
Sbjct: 128 DTTGNVAVVSSPVN 141


>UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4;
           Lactobacillus|Rep: L-lactate dehydrogenase -
           Lactobacillus reuteri
          Length = 312

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 31/85 (36%), Positives = 48/85 (56%)
 Frame = +3

Query: 255 ADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIA 434
           AD++ +  P K+  + G  E +    DADVVVI  G+PR+PG TR DL N N +I++ I 
Sbjct: 53  ADITPLTNPVKI--YAGTYEDAA---DADVVVITAGIPRKPGETRLDLVNKNTTILKSII 107

Query: 435 LSIAXNAPKAIVAIITNPVNFYSAL 509
             I  +    +  I +NPV+  + +
Sbjct: 108 KPIVKSGFTGVFVISSNPVDILTTI 132


>UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2;
           Planctomycetaceae|Rep: L-lactate/malate dehydrogenase -
           Rhodopirellula baltica
          Length = 304

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 36/113 (31%), Positives = 58/113 (51%), Gaps = 2/113 (1%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIA-PVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
           +G  +A  L  NPL + L L + +     G A DL+H       +      E++ + KD+
Sbjct: 11  VGSAIAFALTINPLASELLLLNRSREKAEGDALDLTHAAALVDSNIKISSGEIADS-KDS 69

Query: 339 DVVVIPXGVP-REPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           DV++    VP R P  TR ++   N  I+RD    +A  +P AIV +++NPV+
Sbjct: 70  DVIIFTASVPFRYPNQTRLEMGIDNMPILRDWMPGLAKASPNAIVVMVSNPVD 122


>UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=2;
           Desulfitobacterium hafniense|Rep: Malate dehydrogenase,
           NAD-dependent - Desulfitobacterium hafniense (strain
           DCB-2)
          Length = 320

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 22/54 (40%), Positives = 38/54 (70%)
 Frame = +3

Query: 333 DADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           D+DVVVI  G+ R+PGM+R++L + NA IV  +   +  ++P + + I++NPV+
Sbjct: 71  DSDVVVITAGIARKPGMSRNELCDINAGIVTHVVRQVVQHSPNSTLIILSNPVD 124


>UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2;
           Gammaproteobacteria|Rep: Lactate dehydrogenase -
           Reinekea sp. MED297
          Length = 319

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 33/83 (39%), Positives = 44/83 (53%), Gaps = 2/83 (2%)
 Frame = +3

Query: 246 GVAADLSHVN--TPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASI 419
           G   D  H N  T +K    +  ++ S  + DAD+VVI  G   + G TRDDL   N+ I
Sbjct: 40  GEMMDFGHANSLTFSKNIRLRAGDDYSL-LTDADIVVITAGAQIKEGQTRDDLAEINSRI 98

Query: 420 VRDIALSIAXNAPKAIVAIITNP 488
             DIA  I   AP AI+ ++TNP
Sbjct: 99  TVDIAQKIETVAPNAILLVVTNP 121


>UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacter
           fetus subsp. fetus 82-40|Rep: Malate dehydrogenase -
           Campylobacter fetus subsp. fetus (strain 82-40)
          Length = 306

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 24/56 (42%), Positives = 37/56 (66%)
 Frame = +3

Query: 327 IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           +KD D+VVI  G  R+ G +RDDL   NA IV   +  ++  APK+I+ ++TNP++
Sbjct: 67  LKDFDIVVITAGFARKDGQSRDDLAMMNAKIVSHSSKMVSKFAPKSIIIVVTNPLD 122


>UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium
           (Plasmodium)|Rep: Lactate dehydrogenase - Plasmodium
           vivax
          Length = 299

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 43/127 (33%), Positives = 62/127 (48%), Gaps = 10/127 (7%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPA----KVSGHKGPEELSXA 326
           IG  +A L+ Q  L   + ++D+    P G A D SH N  A    KV+G    ++L   
Sbjct: 8   IGGVMATLIVQKNLGD-VVMFDVVKNMPQGKALDTSHSNVMAYSNCKVTGSNSYDDL--- 63

Query: 327 IKDADVVVIPXGVPREPGMT-----RDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPV 491
            K ADVV++  G  + PG +     RDDL   N  I+ +I   I    P A + ++TNPV
Sbjct: 64  -KGADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKNLCPNAFIIVVTNPV 122

Query: 492 NFYSALL 512
           +    LL
Sbjct: 123 DVMVQLL 129


>UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11;
           Clostridium|Rep: L-lactate dehydrogenase - Clostridium
           perfringens
          Length = 317

 Score = 52.8 bits (121), Expect = 5e-06
 Identities = 33/112 (29%), Positives = 54/112 (48%), Gaps = 1/112 (0%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
           +G   A  L Q+ L + + + DI        A DL+      K    K  +      KD+
Sbjct: 17  VGSTTAFALMQDGLASEIVIVDINKDKAHAEAMDLAQGAAFVKSVDIKSGDYADT--KDS 74

Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           D+V+I  GV  +PG TR D+ N N  I + I   +   +P +I+ +++NPV+
Sbjct: 75  DIVIITAGVGPKPGETRLDIINKNLKIFQSIVPEVVKYSPNSILLVVSNPVD 126


>UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12;
           Firmicutes|Rep: L-lactate dehydrogenase 2 - Bacillus
           anthracis
          Length = 314

 Score = 52.8 bits (121), Expect = 5e-06
 Identities = 34/83 (40%), Positives = 41/83 (49%)
 Frame = +3

Query: 246 GVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVR 425
           G A DLSH   P   S  K         KDAD+VVI  G+P++PG TR DL   N  I +
Sbjct: 45  GEAMDLSHA-VPFSPSPTKVWSGSYADCKDADLVVITAGLPQKPGETRLDLVEKNTKIFK 103

Query: 426 DIALSIAXNAPKAIVAIITNPVN 494
            I   I  +    I  I TNPV+
Sbjct: 104 QIVRGIMDSGFDGIFLIATNPVD 126


>UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1;
           Eubacterium ventriosum ATCC 27560|Rep: Putative
           uncharacterized protein - Eubacterium ventriosum ATCC
           27560
          Length = 312

 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 25/55 (45%), Positives = 34/55 (61%)
 Frame = +3

Query: 330 KDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           KDAD++VI  GVPR PG TR D+ + +   VRDI  ++     K I+  ITNP +
Sbjct: 71  KDADIIVISAGVPRLPGQTRLDVLDGSVECVRDIVSNLNKIEIKGIIITITNPAD 125


>UniRef50_O26290 Cluster: Malate dehydrogenase; n=2;
           Methanobacteriaceae|Rep: Malate dehydrogenase -
           Methanobacterium thermoautotrophicum
          Length = 325

 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 26/51 (50%), Positives = 32/51 (62%)
 Frame = +3

Query: 342 VVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           +VVI  GVPR   M RDDL   N  IV D A  IA  AP +I+ ++TNPV+
Sbjct: 75  IVVITAGVPRTADMDRDDLAFKNGRIVADYARQIARFAPDSIILVVTNPVD 125


>UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2;
           Ruminococcus|Rep: Putative uncharacterized protein -
           Ruminococcus torques ATCC 27756
          Length = 316

 Score = 52.0 bits (119), Expect = 8e-06
 Identities = 38/113 (33%), Positives = 56/113 (49%), Gaps = 2/113 (1%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSH-VNTPAKVSGHKGPEELSXAIKD 335
           +G  +A  L Q  L + + L D       G A D+SH +     +  + G  E    I D
Sbjct: 15  VGSTIAYTLMQKGLFSEMVLLDANKAKAEGEAMDISHGLPFTHAMDIYAGEYE---DIAD 71

Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           A VV+I  G  ++PG TR DL   NA+I+R I   I     + I+ I++NPV+
Sbjct: 72  ASVVIITAGANQKPGETRLDLVQKNAAIMRSIIKEIKRVNCEGILLIVSNPVD 124


>UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3;
           Methanomicrobiales|Rep: L-lactate dehydrogenase -
           Methanocorpusculum labreanum (strain ATCC 43576 / DSM
           4855 / Z)
          Length = 319

 Score = 52.0 bits (119), Expect = 8e-06
 Identities = 38/123 (30%), Positives = 62/123 (50%), Gaps = 7/123 (5%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIA---PVTPGVAADLSHV----NTPAKVSGHKGPEELS 320
           +G  +A  + Q P V  + LY          G+A D+        T  +V+    P+EL 
Sbjct: 13  VGSYVAHAVSQFPHVQEMCLYGRPGNEQYLDGLAHDMMDSFAARGTNTRVTFGTTPKEL- 71

Query: 321 XAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFY 500
              + +D++V+  GVPR+   TR DL   NA IV+  A  +   AP+AI+ ++TNPV+  
Sbjct: 72  ---RGSDIIVLTSGVPRKATQTRLDLALENARIVKVFAEQVGRMAPEAILLVVTNPVDIM 128

Query: 501 SAL 509
           + +
Sbjct: 129 TTV 131


>UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17;
           Bacteria|Rep: L-lactate dehydrogenase 2 -
           Bifidobacterium longum
          Length = 320

 Score = 52.0 bits (119), Expect = 8e-06
 Identities = 35/115 (30%), Positives = 55/115 (47%), Gaps = 4/115 (3%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSHVNT---PAKVSGHKGPEELSXAI 329
           +G  LA    Q  +   + L DIA         D+ H ++      + G   PE      
Sbjct: 19  VGSTLAFAAAQRGIAREIVLEDIAKERVEAEVLDMQHGSSFYPTVSIDGSDDPE----IC 74

Query: 330 KDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           +DAD+VVI  G  ++PG +R +L     +I++ I  ++   AP AI  +ITNPV+
Sbjct: 75  RDADMVVITAGPRQKPGQSRLELVGATVNILKAIMPNLVKVAPNAIYMLITNPVD 129


>UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140;
           Bacteria|Rep: L-lactate dehydrogenase - Streptococcus
           pneumoniae
          Length = 328

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 38/133 (28%), Positives = 57/133 (42%), Gaps = 6/133 (4%)
 Frame = +3

Query: 114 TSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPV---TPGVAADLSHV---N 275
           TS +  K         +G   A  L    +   L + +I  +     G A DLSH     
Sbjct: 2   TSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLHEKAVGDALDLSHALAFT 61

Query: 276 TPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNA 455
           +P K+   +  +       DAD+VVI  G P++PG TR DL   N +I + I   +  + 
Sbjct: 62  SPKKIYAAQYSD-----CADADLVVITAGAPQKPGETRLDLVGKNLAINKSIVTQVVESG 116

Query: 456 PKAIVAIITNPVN 494
            K I  +  NPV+
Sbjct: 117 FKGIFLVAANPVD 129


>UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasma
           hyopneumoniae|Rep: L-lactate dehydrogenase - Mycoplasma
           hyopneumoniae
          Length = 315

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 24/56 (42%), Positives = 35/56 (62%)
 Frame = +3

Query: 327 IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           +KDAD +VI  G P++PG TR +L   N  I+R+IAL +  +    I  I+ NPV+
Sbjct: 69  LKDADFIVITAGRPQKPGETRLELVADNIRIIREIALKVKESGFSGISIIVANPVD 124


>UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex
           aeolicus|Rep: Malate dehydrogenase 2 - Aquifex aeolicus
          Length = 334

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 24/69 (34%), Positives = 40/69 (57%)
 Frame = +3

Query: 288 VSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAI 467
           V G    +E    +K +D+VVI  G+PR  GM+R+DL   N  I++    +I   A  +I
Sbjct: 73  VKGISYDKEGFEELKGSDIVVITAGIPRREGMSREDLLYENLKILKKFTDAIKEYAKDSI 132

Query: 468 VAIITNPVN 494
           + +++NPV+
Sbjct: 133 IIVVSNPVD 141


>UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2;
           Bacteria|Rep: L-lactate dehydrogenase - Treponema
           denticola
          Length = 315

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 36/113 (31%), Positives = 57/113 (50%), Gaps = 2/113 (1%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSH-VNTPAKVSGHKGPEELSXAIKD 335
           +G   A  L Q+     +A+ D+      G A DL   +    +V  H G ++   A  D
Sbjct: 16  VGSTFAYALAQSGYADEIAITDMNKNFAEGQALDLVQGLPFLPQVDIHAG-DKTDYA--D 72

Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           +D+VV+  G  ++ G TR DL   NASI+  IA  IA +    ++ I++NPV+
Sbjct: 73  SDIVVVTAGAKQQSGETRIDLLKRNASIITGIAKDIAESGCSGVMLIVSNPVD 125


>UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular
           organisms|Rep: Malate dehydrogenase - Dehalococcoides
           sp. (strain CBDB1)
          Length = 307

 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 19/53 (35%), Positives = 36/53 (67%)
 Frame = +3

Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           +++VVI  G+ R+PGMTR++L   N  I+ D+  +    +P+A + +++NPV+
Sbjct: 70  SEIVVITAGIARKPGMTREELLAINQKIMTDVVSNCLKYSPEATLVVVSNPVD 122


>UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7;
           Bacteria|Rep: L-lactate dehydrogenase - Deinococcus
           radiodurans
          Length = 304

 Score = 49.2 bits (112), Expect = 6e-05
 Identities = 26/71 (36%), Positives = 40/71 (56%)
 Frame = +3

Query: 297 HKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAI 476
           H G  EL+    DA VV++  G  ++PG +R DL   NA I R++   I   AP A++ +
Sbjct: 59  HGGHSELA----DAQVVILTAGANQKPGESRLDLLEKNADIFRELVPQITRAAPDAVLLV 114

Query: 477 ITNPVNFYSAL 509
            +NPV+  + L
Sbjct: 115 TSNPVDLLTDL 125


>UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7;
           Halobacteriaceae|Rep: Malate dehydrogenase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 304

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 1/86 (1%)
 Frame = +3

Query: 240 TPGVAADLSH-VNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNAS 416
           T G AAD +H +   +     +G  E +     +DVVVI  G+PR+PG TR DL   NA 
Sbjct: 42  TVGQAADTNHGIAYDSNTRVRQGGYEDTAG---SDVVVITAGIPRQPGQTRIDLAGDNAP 98

Query: 417 IVRDIALSIAXNAPKAIVAIITNPVN 494
           I+ DI  S+  +    I    +NPV+
Sbjct: 99  IMEDIQSSLDEHNDDYISLTTSNPVD 124


>UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2;
           Ascomycota|Rep: Probable L-lactate dehydrogenase -
           Schizosaccharomyces pombe (Fission yeast)
          Length = 330

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 45/141 (31%), Positives = 63/141 (44%), Gaps = 7/141 (4%)
 Frame = +3

Query: 93  GAKNFSTTSQRN--FKXXXXXXXXX--IGQPLALLLKQNPLVTRLALYDI-APVTPGVAA 257
           G+K FS  S R+  FK           +G   A  L  + L   + + D+      G A 
Sbjct: 4   GSKVFSNDSVRSSSFKSIKIVIVGAGNVGSTTAFTLLLSGLAAEIVIIDLNKKKAEGEAM 63

Query: 258 DLSHVNTPAKVSGHKGPEELSXA--IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDI 431
           DL+H    A +S H+    L      KDA  VVI  G  ++PG TR DL   N SI ++I
Sbjct: 64  DLNHA---APLS-HETRVYLGDYKDCKDATAVVITAGKNQKPGETRMDLLKANISIFKEI 119

Query: 432 ALSIAXNAPKAIVAIITNPVN 494
              +      AI+ + TNPV+
Sbjct: 120 LREVTKYTKDAILLVATNPVD 140


>UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
           mobile|Rep: L-lactate dehydrogenase - Mycoplasma mobile
          Length = 318

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 23/56 (41%), Positives = 36/56 (64%)
 Frame = +3

Query: 327 IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           +KD DVVVI  G P++PG TR ++   NA I+ +IA +I  +  K +  ++ NPV+
Sbjct: 71  LKDYDVVVITAGRPQKPGETRLEMVADNAKIMSNIAKNIKKSGFKGVSIVVANPVD 126


>UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula
           stellata E-37|Rep: L-lactate dehydrogenase - Sagittula
           stellata E-37
          Length = 300

 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 4/115 (3%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSHVNTPAKVSGH---KGPEELSXAI 329
           +G   A       + + + L D+        A D++H   P  VS      G ++LS A 
Sbjct: 2   VGSAAAFACIMRGVASEIVLVDLDTARAQAEAEDIAHA-VPFSVSARIVAGGYDDLSGA- 59

Query: 330 KDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
              DVV++  GV ++PG +R +L + NA + R +   +   AP AI+ I +NPV+
Sbjct: 60  ---DVVILACGVSQKPGESRLELLSRNAEVFRAVVGDVTRAAPDAILLIASNPVD 111


>UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;
           Clostridium|Rep: L-lactate dehydrogenase precursor -
           Clostridium thermocellum (strain ATCC 27405 / DSM 1237)
          Length = 318

 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 30/119 (25%), Positives = 56/119 (47%), Gaps = 2/119 (1%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSH-VNTPAKVSGHKGPEELSXAIKD 335
           +G   A  +        L L D+      G A D++H +    ++S + G       +KD
Sbjct: 18  VGASAAFTMALRQTANELVLIDVFKEKAIGEAMDINHGLPFMGQMSLYAGDYS---DVKD 74

Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSALL 512
            DV+V+  G  R+PG TR DL   N  I +++  +I       ++ +++NPV+  + ++
Sbjct: 75  CDVIVVTAGANRKPGETRLDLAKKNVMIAKEVTQNIMKYYNHGVILVVSNPVDIITYMI 133


>UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4;
           Bacteroidales|Rep: Malate dehydrogenase - Porphyromonas
           gingivalis (Bacteroides gingivalis)
          Length = 334

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 36/113 (31%), Positives = 47/113 (41%), Gaps = 2/113 (1%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYD-IAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
           IG  +A       L   L LYD  A    GVA ++ H              ++  A+ DA
Sbjct: 18  IGSNMAQTAAMMRLTPNLCLYDPFAVGLEGVAEEIRHCGFEGL--NLTFTSDIKEALTDA 75

Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKA-IVAIITNPVN 494
             +V   G PR+ GMTR+DL   NA I   +   I    P    V II NP +
Sbjct: 76  KYIVSSGGAPRKEGMTREDLLKGNAEIAAQLGKDIKSYCPDCKHVIIIFNPAD 128


>UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;
           Candidatus Methanoregula boonei 6A8|Rep: L-lactate
           dehydrogenase precursor - Methanoregula boonei (strain
           6A8)
          Length = 332

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 23/56 (41%), Positives = 33/56 (58%)
 Frame = +3

Query: 327 IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           +  +D+VVI  G PR PG  R DL   NA I+  +A +I   AP   + ++TNPV+
Sbjct: 71  VAGSDIVVITAGTPRGPGQNRLDLALGNARIIAPMARTIGTIAPDTKIIMVTNPVD 126


>UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia
           burgdorferi group|Rep: L-lactate dehydrogenase -
           Borrelia burgdorferi (Lyme disease spirochete)
          Length = 316

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 37/116 (31%), Positives = 54/116 (46%), Gaps = 5/116 (4%)
 Frame = +3

Query: 162 IGQPLALLLK-QNPLVTRLALYDIAP-VTPGVAADLSHVNTPAKVSGHKGPEELSXAIKD 335
           +G   A  L   N LV  L + D+      G   DL+H     K    K    L    KD
Sbjct: 15  VGSSFAYALTIDNSLVHELVIIDVNENKAKGEVMDLNHGQMFLK----KNINVLFGTYKD 70

Query: 336 ---ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
              AD+VVI  G+ ++PG TR DL + N+ I +DI  ++  +    I  + +NPV+
Sbjct: 71  CANADIVVITAGLNQKPGETRLDLVDKNSKIFKDIITNVVSSGFDGIFVVASNPVD 126


>UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metazoa
           group|Rep: Malate dehydrogenase - Plicopurpura patula
          Length = 229

 Score = 46.4 bits (105), Expect = 4e-04
 Identities = 22/34 (64%), Positives = 25/34 (73%)
 Frame = +3

Query: 393 DLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           DLFNTNA IVRD+   IA   P A++ IITNPVN
Sbjct: 1   DLFNTNAGIVRDLTDRIAKVCPTAMLGIITNPVN 34


>UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular
           organisms|Rep: Malate dehydrogenase - Ostreococcus tauri
          Length = 477

 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 20/38 (52%), Positives = 27/38 (71%)
 Frame = +3

Query: 381 MTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           MTRDDLF  N  IV+ +  +IA N P A++ +I+NPVN
Sbjct: 1   MTRDDLFAINGGIVKGLVEAIADNCPNAMINMISNPVN 38


>UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to
           ENSANGP00000020184; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ENSANGP00000020184 - Nasonia
           vitripennis
          Length = 352

 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 35/130 (26%), Positives = 59/130 (45%), Gaps = 1/130 (0%)
 Frame = +3

Query: 108 STTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAK 287
           ++++ RN K          G+ LAL LKQ+ L+  LA+YD  P T G+  +LSH+++  +
Sbjct: 29  TSSNSRNLKVAIVGATGQTGRSLALCLKQSALIDELAVYDSHP-TRGLLLELSHMDSRCR 87

Query: 288 VSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRD-DLFNTNASIVRDIALSIAXNAPKA 464
                     S      D+     G  +   +T D +     A  +  I   +    PKA
Sbjct: 88  TIVEDEASTTSACNGKRDLERALTGA-KIVAITLDGESIREEAEYLEKILSGLLGCCPKA 146

Query: 465 IVAIITNPVN 494
           +VA+++  VN
Sbjct: 147 LVALVSRRVN 156


>UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6;
           Bacteria|Rep: L-lactate dehydrogenase - Acidobacteria
           bacterium (strain Ellin345)
          Length = 321

 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 34/115 (29%), Positives = 49/115 (42%), Gaps = 1/115 (0%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIA-PVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
           +G   A  L Q  L   + L D       G A DL+H   P   +      E +   + A
Sbjct: 21  VGASFAFALLQRRLAAEIVLIDANHKKAEGEAMDLNHA-VPFGAATRIWAGEYADC-RGA 78

Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYS 503
            V VI  G  + PG TR  L + N +I + I   +  + P  ++ I TNPV+  S
Sbjct: 79  AVTVITAGAAQRPGETRLQLLDRNLAIFQQIVPEVVKHNPDGLLLIATNPVDIIS 133


>UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;
           Clostridium phytofermentans ISDg|Rep: L-lactate
           dehydrogenase precursor - Clostridium phytofermentans
           ISDg
          Length = 325

 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 22/55 (40%), Positives = 31/55 (56%)
 Frame = +3

Query: 330 KDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           KDAD+VVI  G P +PG +R D    +A IV  I   +  +    I  ++TNPV+
Sbjct: 74  KDADIVVITAGPPPKPGQSRLDTLGLSADIVSTIVEPVMKSGFNGIFLVVTNPVD 128


>UniRef50_Q8ELF0 Cluster: L-lactate dehydrogenase; n=5;
           Bacillaceae|Rep: L-lactate dehydrogenase -
           Oceanobacillus iheyensis
          Length = 321

 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 37/128 (28%), Positives = 52/128 (40%), Gaps = 1/128 (0%)
 Frame = +3

Query: 114 TSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTPAKV 290
           TSQ+            +G   A  L    +   LA+ D+ A    G   DL+H    A  
Sbjct: 3   TSQQAVNRVVLIGGGSVGVSYAFALMNQGVTEELAIIDLDADKALGDVMDLNHGKAFAPS 62

Query: 291 SGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIV 470
             +    E     KDAD+V I  G  ++ G TR DL   N  I ++I   +  +    I 
Sbjct: 63  LTNVWLGEYGDC-KDADIVCICAGANQQSGETRLDLVEKNMKIFKEIVTDVMNSGFNGIF 121

Query: 471 AIITNPVN 494
            I TNPV+
Sbjct: 122 LIATNPVD 129


>UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
           pulmonis|Rep: L-lactate dehydrogenase - Mycoplasma
           pulmonis
          Length = 315

 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 25/88 (28%), Positives = 44/88 (50%)
 Frame = +3

Query: 246 GVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVR 425
           G A D+S        +G K         K AD++++  G P++ G TR ++   N+ I++
Sbjct: 41  GHAMDMSDAIALNSTTGSKIRTGTYADAKGADLLIVAAGRPQKQGETRLEMIADNSKIMK 100

Query: 426 DIALSIAXNAPKAIVAIITNPVNFYSAL 509
           DIAL I  +       +I+NPV+  + +
Sbjct: 101 DIALEIKKSGFNGFTIVISNPVDILATV 128


>UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9;
           Bacilli|Rep: L-lactate dehydrogenase 2 - Enterococcus
           faecalis (Streptococcus faecalis)
          Length = 317

 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 22/55 (40%), Positives = 35/55 (63%)
 Frame = +3

Query: 330 KDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           +DAD+VVI  G  ++PG +R DL + NA I++ I  +I  +    I+ I +NPV+
Sbjct: 72  QDADIVVITAGANQKPGQSRLDLVSINAEIMKTIVNNIMKSGFDGILVIASNPVD 126


>UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5;
           Bacteroidales|Rep: Malate dehydrogenase - Bacteroides
           fragilis
          Length = 333

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 34/121 (28%), Positives = 49/121 (40%), Gaps = 2/121 (1%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYD-IAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
           IG  +A       L   + LYD  AP   GVA +L H         +    ++  A+  A
Sbjct: 18  IGSNMAQTALMMKLTPNICLYDPYAPALEGVAEELYHCAFEGVNLTYTS--DIKEALSGA 75

Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKA-IVAIITNPVNFYSALLP 515
             +V   G  R+ GMTR+DL   NA I       I    P    V ++ NP +    ++ 
Sbjct: 76  KYIVSSGGAARKAGMTREDLLKGNAEIAAQFGKDIRQYCPDVKHVVVVFNPADITGLIVL 135

Query: 516 L 518
           L
Sbjct: 136 L 136


>UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondrial
           malate dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to mitochondrial malate dehydrogenase
           - Nasonia vitripennis
          Length = 299

 Score = 44.8 bits (101), Expect = 0.001
 Identities = 30/114 (26%), Positives = 54/114 (47%), Gaps = 1/114 (0%)
 Frame = +3

Query: 180 LLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPX 359
           +LLKQNP +  + L D          D+ H++T   +  H     +   +++ D+V +  
Sbjct: 1   MLLKQNPAIKEIRLIDTDNSLMSPVCDMRHIDTSTTIR-HFRKNSILDGLRNTDIVALMD 59

Query: 360 GVPREPGMTRDDL-FNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSALLPL 518
                 G     + F  +++ V+ +A  +    PKA+VA+ T+PV   +A LPL
Sbjct: 60  ETDFMMGNKGPFMQFVNSSNYVKSVAECMINVCPKALVAVFTHPV---TATLPL 110


>UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:
           Lactate dehydrogenase - Vibrio parahaemolyticus
          Length = 317

 Score = 44.8 bits (101), Expect = 0.001
 Identities = 22/51 (43%), Positives = 31/51 (60%)
 Frame = +3

Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNP 488
           AD+VVI  G   + G TR D+   NA I  +IA  I   APKA++ +++NP
Sbjct: 71  ADIVVITAGAQIQQGQTRLDIAEINAKIGVEIARKIERVAPKAVLIVVSNP 121


>UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1;
           Lactobacillus casei ATCC 334|Rep: L-lactate
           dehydrogenase - Lactobacillus casei (strain ATCC 334)
          Length = 312

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 20/61 (32%), Positives = 36/61 (59%)
 Frame = +3

Query: 330 KDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSAL 509
           K AD++VI  G+ ++PG TR  L   NA I+++I  +I  +     + + +NPV+  + L
Sbjct: 70  KYADIIVITAGIAQKPGQTRLQLLAINAKIMKEITHNIMASGFNGFILVASNPVDVLAEL 129

Query: 510 L 512
           +
Sbjct: 130 V 130


>UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium
           tetraurelia|Rep: Malate dehydrogenase - Paramecium
           tetraurelia
          Length = 322

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 24/69 (34%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
 Frame = +3

Query: 324 AIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAI-VAIITNPVNFY 500
           A KDADV +    +PR+PGM R DL   N  I       +   A   + V ++ NP N  
Sbjct: 79  AFKDADVAIFLGAMPRKPGMERSDLLQMNREIFIQQGQILNEQAKSTVKVLVVANPSNTN 138

Query: 501 SALLPLKCS 527
            A L  +C+
Sbjct: 139 CATLAHQCT 147


>UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibacter
           ruber DSM 13855|Rep: L-lactate dehydrogenase -
           Salinibacter ruber (strain DSM 13855)
          Length = 316

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 21/58 (36%), Positives = 35/58 (60%), Gaps = 1/58 (1%)
 Frame = +3

Query: 324 AIKDADVVVIPXGVPRE-PGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           A+ +A ++V+  G  ++ P  TR  L   NA I R+I + +  +AP AI+ + TNPV+
Sbjct: 68  ALSNAQIIVLSAGASQQSPDETRLGLLQRNAEIFREIIIQLDKHAPNAILVVATNPVD 125


>UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridium
           beijerinckii NCIMB 8052|Rep: L-lactate dehydrogenase -
           Clostridium beijerinckii NCIMB 8052
          Length = 316

 Score = 44.0 bits (99), Expect = 0.002
 Identities = 36/117 (30%), Positives = 53/117 (45%), Gaps = 3/117 (2%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTPGV-AADLSHV--NTPAKVSGHKGPEELSXAIK 332
           +G  +A  +  N +   L L DI        A DL H    + +K+    G  E      
Sbjct: 16  VGAAVAFDMVMNHVCDDLILIDINKEKSWAEATDLQHSLGYSGSKMRVKDGEYE---ECN 72

Query: 333 DADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYS 503
           DAD+VVI   +P   G TR D+    A I+ +I  +I  +    I+ +ITNPV+  S
Sbjct: 73  DADIVVIAAALPYITGQTRLDMLEKAAGIMNNIVPNIMKSGFSGIIVVITNPVDVMS 129


>UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomonas
           ruminantium|Rep: L-lactate dehydrogenase - Selenomonas
           ruminantium
          Length = 318

 Score = 44.0 bits (99), Expect = 0.002
 Identities = 35/117 (29%), Positives = 53/117 (45%), Gaps = 6/117 (5%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNT---PAKVSGHKGPEELSXAI 329
           +G  +A  +    L T + L D+      G A D SH  +      +  H G  E     
Sbjct: 15  VGSAVANKIADFQLATEVVLIDLNEDKAWGEAKDSSHATSCIYSTNIKFHLGDYE---DC 71

Query: 330 KDADVVVIPXGVPREPGMTRD--DLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           KDA+++VI  G    PG T D   L  TNA I+  +   I     +A++ +ITNP++
Sbjct: 72  KDANIIVITAGPSIRPGETPDRLKLAGTNAKIMSSVMGEIVKRTKEAMIIMITNPLD 128


>UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6;
           Mollicutes|Rep: L-lactate dehydrogenase - Mesoplasma
           florum (Acholeplasma florum)
          Length = 317

 Score = 44.0 bits (99), Expect = 0.002
 Identities = 21/53 (39%), Positives = 32/53 (60%)
 Frame = +3

Query: 330 KDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNP 488
           KDAD++VI  G P+ PG TR +L   N+ I++ IA +I  +    +  I +NP
Sbjct: 72  KDADLIVITAGRPQRPGETRLELIADNSRIMKGIAEAIKASGFNGVTVIASNP 124


>UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14;
           Bacillales|Rep: L-lactate dehydrogenase X - Bacillus
           psychrosaccharolyticus
          Length = 319

 Score = 44.0 bits (99), Expect = 0.002
 Identities = 35/128 (27%), Positives = 51/128 (39%), Gaps = 3/128 (2%)
 Frame = +3

Query: 120 QRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSH--VNTPAKV 290
           QRN           +G   A  L    +   L + D+      G A DL+H  +  P   
Sbjct: 3   QRNINRVALIGAGSVGSSYAFALLNQSITEELVIIDVNEDKAMGDAMDLNHGKIFAPNPT 62

Query: 291 SGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIV 470
               G  +     K+AD+V I  G  ++PG TR DL   N  I + +   +  +    I 
Sbjct: 63  KTWYGNYD---DCKEADIVCICAGANQKPGETRLDLVEKNLKIFKSLVDQVMASGFDGIF 119

Query: 471 AIITNPVN 494
            I TNPV+
Sbjct: 120 LIATNPVD 127


>UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6;
           Actinomycetales|Rep: Lactate/malate dehydrogenase -
           Mycobacterium sp. (strain KMS)
          Length = 329

 Score = 43.6 bits (98), Expect = 0.003
 Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 2/96 (2%)
 Frame = +3

Query: 213 LALYDI--APVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMT 386
           LALYD   A V   V  DL+H +         G ++++     A +VV+  G  + PG +
Sbjct: 46  LALYDTNSAKVRAEVL-DLNHGSQFVPECRVGGSDDIAVTAGSA-IVVVTAGAKQHPGQS 103

Query: 387 RDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           R DL   N ++ + +   +  ++P A+V  +TNPV+
Sbjct: 104 RLDLAAANVAMAQTLTPQLLEHSPDAVVIFVTNPVD 139


>UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1;
           Thermosinus carboxydivorans Nor1|Rep: Lactate/malate
           dehydrogenase - Thermosinus carboxydivorans Nor1
          Length = 303

 Score = 43.6 bits (98), Expect = 0.003
 Identities = 19/58 (32%), Positives = 34/58 (58%)
 Frame = +3

Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSAL 509
           AD+VVI  G+PR+    R  L + NA+++ D+       +P  I+ ++TNP++  + L
Sbjct: 68  ADIVVITAGIPRKADEPRVLLLSRNAALIADLVRQAVHYSPNCIIFMVTNPLDVMTQL 125


>UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12;
           Campylobacter|Rep: Probable malate dehydrogenase -
           Campylobacter jejuni
          Length = 300

 Score = 43.6 bits (98), Expect = 0.003
 Identities = 20/56 (35%), Positives = 32/56 (57%)
 Frame = +3

Query: 330 KDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNF 497
           K++D+V+   G  R+ G +R++L   N SI+ D A  I       +  I+TNPV+F
Sbjct: 68  KNSDIVLFSAGFARKDGQSREELLQLNTSIMLDCAKKIKDFTEDPLFIILTNPVDF 123


>UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate
           dehydrogenases; n=2; Nostoc punctiforme PCC 73102|Rep:
           COG0039: Malate/lactate dehydrogenases - Nostoc
           punctiforme PCC 73102
          Length = 317

 Score = 42.7 bits (96), Expect = 0.005
 Identities = 22/57 (38%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
 Frame = +3

Query: 327 IKDADVVVI-PXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           + D+D+++I   GV  + G TR D  + NA I+R     +   AP +IV II+NPV+
Sbjct: 71  LADSDIIIIVTAGVQPKLGQTRLDTLSDNAEIIRSTIKELDRVAPNSIVIIISNPVD 127


>UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4;
           Bacteria|Rep: L-lactate dehydrogenase - Blastopirellula
           marina DSM 3645
          Length = 313

 Score = 42.7 bits (96), Expect = 0.005
 Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 3/119 (2%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
           +G   A  L+   +   +AL D+ A +  G A DL H   P+ V+           I D+
Sbjct: 12  VGSCAAFALQCGGIAREIALLDLNADLAGGHALDLLH-GAPS-VADQVITSGGYEHIPDS 69

Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPK--AIVAIITNPVNFYSAL 509
           DV+ I  G+ R+P  +R DL N N  +   I  S+     K  AI  +++NPV+  + L
Sbjct: 70  DVICITAGLRRKPDESRLDLINRNVDLFLSILDSVKSAGVKKDAICFVVSNPVDILTYL 128


>UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic,
           putative; n=3; Oligohymenophorea|Rep: Malate
           dehydrogenase, cytoplasmic, putative - Tetrahymena
           thermophila SB210
          Length = 365

 Score = 42.7 bits (96), Expect = 0.005
 Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
 Frame = +3

Query: 237 VTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNAS 416
           +  GV  +L     P   S   G  E S   +D DV V   G PR+PGM R DL   N +
Sbjct: 89  ILQGVELELQDGAYPLLKSIKTGSNE-SILFQDVDVAVFIGGFPRKPGMERKDLLTINGN 147

Query: 417 IVRDIALSIAXNAPKAIVA-IITNPVN 494
           I +    ++   A K   + ++ NP N
Sbjct: 148 IFKKQGQALDTVAKKTCKSLVVANPAN 174


>UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1;
           Methanoculleus marisnigri JR1|Rep: Lactate/malate
           dehydrogenase - Methanoculleus marisnigri (strain ATCC
           35101 / DSM 1498 / JR1)
          Length = 288

 Score = 42.3 bits (95), Expect = 0.007
 Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 2/113 (1%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
           +G   A L     LV  + +YD+  P+      DL H      +S        + A++DA
Sbjct: 12  VGGETAFLSAALGLVDEIVVYDVYEPLLRAQVLDLQHTGIDVAISTE------TAAMRDA 65

Query: 339 DVVVIPXGVPREPGM-TRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           D+ V   G PR P + TR DL   N  + +  +  +    P  +++ +TNP++
Sbjct: 66  DIFVFAAGTPRTPDIKTRADLLEANIPVAKRCS-ELLEGFPGVVIS-VTNPMD 116


>UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2;
           Desulfovibrio vulgaris subsp. vulgaris|Rep: L-lactate
           dehydrogenase - Desulfovibrio vulgaris (strain
           Hildenborough / ATCC 29579 / NCIMB8303)
          Length = 309

 Score = 41.5 bits (93), Expect = 0.012
 Identities = 20/53 (37%), Positives = 29/53 (54%)
 Frame = +3

Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           A +VV+  G  + PG +R DL   NA I RDI  ++   A   +  + TNPV+
Sbjct: 69  ARIVVVTAGAKQMPGQSRLDLVRVNAGITRDILTAVMQYADDPLYIMATNPVD 121


>UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Rep:
           Malate dehydrogenase - Bdellovibrio bacteriovorus
          Length = 335

 Score = 40.7 bits (91), Expect = 0.020
 Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
 Frame = +3

Query: 324 AIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNA-PKAIVAIITNPVN 494
           A KDADV ++    PR PGM R DL   N  I      +I   A P   V ++ NP N
Sbjct: 79  AFKDADVALLVGARPRGPGMERKDLLTANGQIFTVQGEAIGKYANPNVKVLVVGNPAN 136


>UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;
           Theileria|Rep: L-lactate dehydrogenase, putative -
           Theileria annulata
          Length = 367

 Score = 40.3 bits (90), Expect = 0.027
 Identities = 17/36 (47%), Positives = 25/36 (69%)
 Frame = +3

Query: 387 RDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           RDDL   N+ I+RD+  +I   AP+A V +ITNP++
Sbjct: 143 RDDLVGYNSKIIRDVGENIKKYAPEAFVIVITNPMD 178


>UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13;
           Firmicutes|Rep: L-lactate dehydrogenase 3 - Bacillus
           anthracis
          Length = 316

 Score = 40.3 bits (90), Expect = 0.027
 Identities = 32/114 (28%), Positives = 50/114 (43%), Gaps = 3/114 (2%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSH-VN-TPAKVSGHKGPEELSXAIK 332
           +G   A  +    +   L L DI      G A DLSH +N T  +   + G  E     K
Sbjct: 16  VGSSCAYSIVNQGICEELLLIDINHERAVGEAMDLSHCINFTNTRTKVYAGSYE---DCK 72

Query: 333 DADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           D D+V+I  G   +PG +R D    +A I+  +   +  +    I  + +NPV+
Sbjct: 73  DMDIVIITAGPAPKPGQSRLDTLGASAKIMESVVGGVMESGFDGIFLLASNPVD 126


>UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4;
           Trichomonadida|Rep: Cytosolic malate dehydrogenase -
           Tetratrichomonas gallinarum
          Length = 314

 Score = 39.1 bits (87), Expect = 0.062
 Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
 Frame = +3

Query: 288 VSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAI 467
           V+G    +++  A KD DV  +    PR+ GM R DL   N  I      +++  A K +
Sbjct: 46  VAGIVWTDKIEEAFKDVDVAFLVGSFPRKDGMDRSDLLAKNGGIFTVQGKALSDFAKKDV 105

Query: 468 -VAIITNPVN 494
            V ++ NP N
Sbjct: 106 KVLVVGNPAN 115


>UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1;
           Corynebacterium jeikeium K411|Rep: L-lactate
           dehydrogenase - Corynebacterium jeikeium (strain K411)
          Length = 326

 Score = 38.3 bits (85), Expect = 0.11
 Identities = 32/115 (27%), Positives = 48/115 (41%), Gaps = 1/115 (0%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
           +G   A  L    L   LA+ D+    T G   DL+H   P      +         +DA
Sbjct: 26  VGIAYAYTLVNQGLTDHLAIIDLDERKTWGHVQDLNHA-VPWSHHNTRVTVGTYEDCRDA 84

Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYS 503
            +V I  G  ++PG TR DL   N +I + I   +  +    I  + +NPV+  S
Sbjct: 85  AMVCICAGAAQKPGETRLDLVAKNTAIFKTIVGDVMSHGFNGIFLVASNPVDILS 139


>UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizopus
           oryzae|Rep: L-lactate dehydrogenase A - Rhizopus oryzae
           (Rhizopus delemar)
          Length = 320

 Score = 38.3 bits (85), Expect = 0.11
 Identities = 26/112 (23%), Positives = 47/112 (41%), Gaps = 1/112 (0%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
           +G   A  L    + T + + D+ P +      DL+   + +      G  E +     A
Sbjct: 15  VGASTAYALMFKNICTEIIIVDVNPDIVQAQVLDLADAASISHTPIRAGSAEEAG---QA 71

Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           D+VVI  G  +  G  R  L   N  +++ I   +    P A++ ++ NPV+
Sbjct: 72  DIVVITAGAKQREGEPRTKLIERNFRVLQSIIGGMQPIRPDAVILVVANPVD 123


>UniRef50_Q017A7 Cluster: Chromosome 06 contig 1, DNA sequence; n=1;
           Ostreococcus tauri|Rep: Chromosome 06 contig 1, DNA
           sequence - Ostreococcus tauri
          Length = 131

 Score = 37.9 bits (84), Expect = 0.14
 Identities = 18/31 (58%), Positives = 20/31 (64%)
 Frame = -1

Query: 334 SLMAXDSSSGPLWPLTLAGVFTWERSAATPG 242
           S  A  SS+ P +P T A VFT E SAATPG
Sbjct: 7   SFSAAPSSASPAYPFTCAAVFTCETSAATPG 37


>UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia
           intestinalis|Rep: Malate dehydrogenase - Giardia lamblia
           ATCC 50803
          Length = 331

 Score = 37.9 bits (84), Expect = 0.14
 Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
 Frame = +3

Query: 246 GVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVR 425
           GVA +L     P  +SG     + + A KD D  ++    PR+ GM R +L + N  I +
Sbjct: 53  GVAMELVDCAFPL-LSGFTLTSDNAEAFKDVDYCLLFGAFPRKAGMERAELLSKNKGIFQ 111

Query: 426 DIALSIAXNA-PKAIVAIITNPVNFYSALL 512
               +I  +A P   + +I NP N  + +L
Sbjct: 112 IQGAAINEHAKPTCRILVIGNPANTNALVL 141


>UniRef50_P83778 Cluster: Malate dehydrogenase, cytoplasmic; n=1;
           Candida albicans|Rep: Malate dehydrogenase, cytoplasmic
           - Candida albicans (Yeast)
          Length = 51

 Score = 33.5 bits (73), Expect(2) = 0.18
 Identities = 19/29 (65%), Positives = 21/29 (72%)
 Frame = +3

Query: 204 VTRLALYDIAPVTPGVAADLSHVNTPAKV 290
           VT LALYDI P   GVAAD+SHV T + V
Sbjct: 1   VTDLALYDIRP---GVAADVSHVPTNSTV 26



 Score = 23.4 bits (48), Expect(2) = 0.18
 Identities = 10/10 (100%), Positives = 10/10 (100%)
 Frame = +3

Query: 396 LFNTNASIVR 425
           LFNTNASIVR
Sbjct: 28  LFNTNASIVR 37


>UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular
           organisms|Rep: Malate dehydrogenase - Acidovorax sp.
           (strain JS42)
          Length = 328

 Score = 37.1 bits (82), Expect = 0.25
 Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 1/84 (1%)
 Frame = +3

Query: 246 GVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVR 425
           GV  +L     P  ++G +   +   A KD D  ++    PR PGM R DL   NA I  
Sbjct: 55  GVIMELEDCAFPL-LAGIEAHSDPMTAFKDTDYALLVGARPRGPGMERADLLAANAQIFT 113

Query: 426 DIALSIAXNAPKAI-VAIITNPVN 494
               ++   A + + V ++ NP N
Sbjct: 114 AQGKALNAVASRNVKVLVVGNPAN 137


>UniRef50_UPI0000DB7268 Cluster: PREDICTED: similar to L-lactate
           dehydrogenase A chain (LDH-A) (LDH muscle subunit)
           (LDH-M); n=2; Apis mellifera|Rep: PREDICTED: similar to
           L-lactate dehydrogenase A chain (LDH-A) (LDH muscle
           subunit) (LDH-M) - Apis mellifera
          Length = 348

 Score = 36.3 bits (80), Expect = 0.44
 Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 1/111 (0%)
 Frame = +3

Query: 174 LALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVV 350
           +A+L K+  L + L   D+   +    A D+SH           G ++ S A +DA V V
Sbjct: 49  IAILFKR--LASELVFIDVNEELAKAEAEDISHGAAFLGNPKIIGTKDYSLA-RDATVCV 105

Query: 351 IPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYS 503
           I  G           L   N +I +D+   +   AP +I+ I+T PV+  S
Sbjct: 106 ITIGDRSTNEQDPSTLLEQNLNIFKDVIPKVCKYAPNSILLIVTAPVDILS 156


>UniRef50_UPI0000D8BD94 Cluster: UPI0000D8BD94 related cluster; n=2;
           Danio rerio|Rep: UPI0000D8BD94 UniRef100 entry - Danio
           rerio
          Length = 732

 Score = 35.9 bits (79), Expect = 0.58
 Identities = 30/115 (26%), Positives = 49/115 (42%), Gaps = 4/115 (3%)
 Frame = +3

Query: 165 GQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHK---GPEELSXAIKD 335
           G P A+LL  NP  T+L    + P+         H N  A+++GH       + S    +
Sbjct: 285 GMPNAVLLSSNPNQTQLNQLTLNPLQLN-----HHPNCSAQLTGHPLTLPRPKFSYMNTN 339

Query: 336 ADVVVIPXGVPREPGMTRDDLFN-TNASIVRDIALSIAXNAPKAIVAIITNPVNF 497
               V+  G      + + D FN TN ++   ++  I+   PK     ++ PVNF
Sbjct: 340 GSAAVVFLGYTAMENLLKADFFNATNDTVNTMMSSVISVTLPKTTNTALSKPVNF 394


>UniRef50_UPI0001554DCB Cluster: PREDICTED: similar to Zinc finger
           protein 160, partial; n=1; Ornithorhynchus anatinus|Rep:
           PREDICTED: similar to Zinc finger protein 160, partial -
           Ornithorhynchus anatinus
          Length = 912

 Score = 35.5 bits (78), Expect = 0.76
 Identities = 17/43 (39%), Positives = 21/43 (48%)
 Frame = +2

Query: 176 GPSTEAESSGDQAGFIRHSACDPRRRSRPFPREHPSQGQRPQG 304
           GP     S G   G +R+SA DP RRS P P       +R +G
Sbjct: 143 GPGEPVRSGGAGEGAVRNSALDPTRRSHPSPIPPRGSRERDEG 185


>UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;
           n=2; Bacteria|Rep: Lactate/malate dehydrogenase
           precursor - Bacillus coagulans 36D1
          Length = 327

 Score = 35.5 bits (78), Expect = 0.76
 Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 5/59 (8%)
 Frame = +3

Query: 333 DADVVVIPXG---VPREPGMTRD--DLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           DADV++   G   +P E     D   L  TNA++VR++   I     +A++  ITNP++
Sbjct: 72  DADVIICAAGPSVLPSEKDEMPDRAGLARTNAAVVREVMAGITKYTKEAVIIFITNPLD 130


>UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1;
           Aspergillus niger|Rep: Catalytic activity: precursor -
           Aspergillus niger
          Length = 307

 Score = 35.5 bits (78), Expect = 0.76
 Identities = 20/58 (34%), Positives = 29/58 (50%)
 Frame = +3

Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSAL 509
           ADVV+I  GV   PG T         SI++ I   +    P AI+ ++ NPV+  + L
Sbjct: 70  ADVVIITAGVNYTPGETTLQHLYHKFSILKSILNEMRPFNPNAIILVVANPVDTLTTL 127


>UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6;
           Trichomonadidae|Rep: Malate dehydrogenase - Trichomonas
           vaginalis G3
          Length = 332

 Score = 35.1 bits (77), Expect = 1.0
 Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
 Frame = +3

Query: 303 GPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNA-PKAIVAII 479
           G  +L  A +D DV  +    P++P     D F  NASI  +   +++  A P   V +I
Sbjct: 69  GTSDLEEAFRDVDVAFLVGSFPKKPSTKLVDYFQRNASIYSEHGRALSDFAKPTVKVLVI 128

Query: 480 TNPVN 494
             P N
Sbjct: 129 GMPTN 133


>UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1;
           Endoriftia persephone 'Hot96_1+Hot96_2'|Rep: Malate
           dehydrogenase NAD-dependent - Endoriftia persephone
           'Hot96_1+Hot96_2'
          Length = 170

 Score = 34.7 bits (76), Expect = 1.3
 Identities = 13/35 (37%), Positives = 23/35 (65%)
 Frame = +3

Query: 390 DDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           DDL + N S+ + +A ++  +AP A V + TNP++
Sbjct: 16  DDLLDINLSVTKKVATAVKQHAPDAFVILTTNPLD 50


>UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2;
           Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma
           agalactiae
          Length = 323

 Score = 34.7 bits (76), Expect = 1.3
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
 Frame = +3

Query: 306 PEELSXAIKDADVVVIPXGVPREPGMT-RDDLFNTNASIVRDIALSIAXNAPKAIVAIIT 482
           P  L    KDADVVVI   +P +   + R  L   NA +++  A  +     K IV +  
Sbjct: 62  PGTLLEDSKDADVVVITASIPADKTFSDRMALAGANAKLMQSFAKDLDAAGFKGIVVVAA 121

Query: 483 NPVNFYSA 506
           NP +  +A
Sbjct: 122 NPCDVMAA 129


>UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8;
           Chlamydiaceae|Rep: Malate dehydrogenase - Chlamydia
           pneumoniae (Chlamydophila pneumoniae)
          Length = 328

 Score = 34.7 bits (76), Expect = 1.3
 Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
 Frame = +3

Query: 315 LSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASI--VRDIALSIAXNAPKAIVAIITNP 488
           L+ A    D   +   VPR PGM R DL   N  I  ++  AL+ A     A + ++ NP
Sbjct: 76  LNDAFDGIDAAFLIGAVPRGPGMERGDLLKQNGQIFSLQGAALNTAAKR-DAKIFVVGNP 134

Query: 489 VN 494
           VN
Sbjct: 135 VN 136


>UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1;
           Clostridium acetobutylicum|Rep: L-lactate dehydrogenase
           2 - Clostridium acetobutylicum
          Length = 320

 Score = 34.7 bits (76), Expect = 1.3
 Identities = 28/101 (27%), Positives = 43/101 (42%), Gaps = 3/101 (2%)
 Frame = +3

Query: 201 LVTRLALYDIAP-VTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREP 377
           L++ + + DI      G A D SH  + A     K          DA ++VI  G   +P
Sbjct: 29  LLSEVVIIDINDNKAKGEALDASHTTSFAYSPNVKVRAGNYEDCADAQIIVITAGPSLKP 88

Query: 378 GMTRDDLF--NTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
               D L   +TN  +   I  +I      AI+ ++TNPV+
Sbjct: 89  DDKLDRLVLADTNVKVTDSIMKNICKYTKDAIIIVVTNPVD 129


>UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2;
           Phaeosphaeria nodorum|Rep: L-lactate dehydrogenase -
           Phaeosphaeria nodorum (Septoria nodorum)
          Length = 326

 Score = 34.3 bits (75), Expect = 1.8
 Identities = 29/112 (25%), Positives = 48/112 (42%), Gaps = 1/112 (0%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
           +G  LA  L    + T + L D    +  G   DLS   T        G  + +     A
Sbjct: 18  VGATLAYTLILQSICTEVLLVDPKTSLLDGQVRDLSDA-TSRSTKVRSGTHQEAG---QA 73

Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           D+VVI  G  ++ G +R  L   N +I+  I  S+   +   ++ ++ NPV+
Sbjct: 74  DIVVITAGAKQKTGESRLSLLTRNLNILSSIFDSMKPISAHTVLLLVANPVD 125


>UniRef50_UPI0000DD82B5 Cluster: PREDICTED: hypothetical protein;
           n=1; Homo sapiens|Rep: PREDICTED: hypothetical protein -
           Homo sapiens
          Length = 258

 Score = 33.9 bits (74), Expect = 2.3
 Identities = 20/41 (48%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
 Frame = +2

Query: 194 ESSGDQAGFIRHSACDPRRRSRPFPRE-HPSQGQRPQGT*G 313
           E  GDQ    RH AC   R S   P E  P  GQRP GT G
Sbjct: 6   EGRGDQERTRRHRACPGCRGSEVSPGEGAPGSGQRPAGTSG 46


>UniRef50_Q4S3J0 Cluster: Chromosome 1 SCAF14749, whole genome
           shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
           Chromosome 1 SCAF14749, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 778

 Score = 33.5 bits (73), Expect = 3.1
 Identities = 18/47 (38%), Positives = 21/47 (44%)
 Frame = +2

Query: 137 GGRWCRRWYRPAFGPSTEAESSGDQAGFIRHSACDPRRRSRPFPREH 277
           G R  R  + P  GP    E  G Q   +RH A  P RR R  P +H
Sbjct: 554 GVRAPRGLHHPGAGPQRAHEGRGRQPAAVRHPAEPPGRRHRERPGDH 600


>UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6;
           Plasmodium|Rep: Oxidoreductase, putative - Plasmodium
           falciparum (isolate 3D7)
          Length = 334

 Score = 33.5 bits (73), Expect = 3.1
 Identities = 34/126 (26%), Positives = 61/126 (48%), Gaps = 9/126 (7%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGHK--GPEELSXAIK 332
           IG  LA ++ +  L   + L+D     P G A D+ H   P   S     G  E++  IK
Sbjct: 17  IGCALAHMICEKNLGD-VVLHDFRKDLPKGRALDILHTR-PLNRSRINILGTNEITD-IK 73

Query: 333 DADVVVIPXGVPREPGMTRDD------LFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           D+ VVV+   V        D+      ++ +N  +++++A S+  + P+A V + T+PV+
Sbjct: 74  DSLVVVVTIEVSEREFAEFDEEDLEKQVYTSNVKLLKEVAKSLKKHCPQAFVVVTTSPVD 133

Query: 495 FYSALL 512
             + +L
Sbjct: 134 CMAKVL 139


>UniRef50_Q5B0T8 Cluster: Putative uncharacterized protein; n=1;
           Emericella nidulans|Rep: Putative uncharacterized
           protein - Emericella nidulans (Aspergillus nidulans)
          Length = 237

 Score = 33.1 bits (72), Expect = 4.1
 Identities = 19/57 (33%), Positives = 27/57 (47%)
 Frame = +3

Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSAL 509
           D+VVI  G     G T  D    N SIVR I   +       ++ I+ NPV+  ++L
Sbjct: 77  DIVVITAGSKYLYGQTSMDYLYRNTSIVRSIINEMKPFRSDTVLLIVANPVDLMTSL 133


>UniRef50_Q8NHM5 Cluster: JmjC domain-containing histone
           demethylation protein 1B; n=56; Euteleostomi|Rep: JmjC
           domain-containing histone demethylation protein 1B -
           Homo sapiens (Human)
          Length = 1336

 Score = 32.7 bits (71), Expect = 5.4
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -2

Query: 144 RPPL*SSSVMWWKSSLHHFVQQ 79
           RPPL SS   WW+SSL +F QQ
Sbjct: 834 RPPLGSSLSPWWRSSLTYFQQQ 855


>UniRef50_UPI0000E80D01 Cluster: PREDICTED: similar to microtubule
            associated protein 1A; n=2; Amniota|Rep: PREDICTED:
            similar to microtubule associated protein 1A - Gallus
            gallus
          Length = 2250

 Score = 31.9 bits (69), Expect = 9.4
 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
 Frame = +3

Query: 276  TPAKVSGHKGPEELSXAI-KDADVVVIPXGVPREPGMTRDDLF-----NTNASIVRDIAL 437
            TP K    K P+  +    +D      P GV  +P  T D++      N   S+V  I  
Sbjct: 2060 TPVKQPSDKSPKSATAKKERDGGEKPKPRGVLVQPPHTEDEVARSSHSNAGKSLVNGIKS 2119

Query: 438  SIAXNAPKAIVAIITNPVNFYS-ALLPLKCS 527
            + A N+PK+ + + T P  +   A +P  CS
Sbjct: 2120 NPASNSPKSSLPVPTGPPVYVDLAYIPNHCS 2150


>UniRef50_UPI000023EEAF Cluster: hypothetical protein FG02077.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG02077.1 - Gibberella zeae PH-1
          Length = 184

 Score = 31.9 bits (69), Expect = 9.4
 Identities = 15/40 (37%), Positives = 22/40 (55%)
 Frame = +3

Query: 207 TRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSXA 326
           T  A   +AP+ P  AA+    +TPA  +  KGPE+ + A
Sbjct: 126 TAAATTTVAPIIPTTAAEEPATSTPAAATPTKGPEQANGA 165


>UniRef50_Q91LF0 Cluster: ORF90; n=1; Shrimp white spot syndrome
           virus|Rep: ORF90 - White spot syndrome virus (WSSV)
          Length = 759

 Score = 31.9 bits (69), Expect = 9.4
 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
 Frame = +3

Query: 222 YDIAPVTPG--VAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPX-GVPREPGMTRD 392
           +D+ P TPG  V   +       K +G +G EE     ++ +  + P    PR PG  RD
Sbjct: 664 FDLPPATPGRNVEEIIKAQRQAVKETGVRGEEE-----EEEEAFIAPIIRQPRTPGNFRD 718

Query: 393 DLFNTNASI 419
           +L + N SI
Sbjct: 719 ELLDVNESI 727


>UniRef50_Q8XN38 Cluster: Probable hexosyltransferase; n=1;
           Clostridium perfringens|Rep: Probable hexosyltransferase
           - Clostridium perfringens
          Length = 409

 Score = 31.9 bits (69), Expect = 9.4
 Identities = 15/33 (45%), Positives = 19/33 (57%)
 Frame = +3

Query: 258 DLSHVNTPAKVSGHKGPEELSXAIKDADVVVIP 356
           D S ++T  K  G   PEEL     DADV++IP
Sbjct: 277 DSSEIDTRIKYLGKLNPEELKQQYIDADVLIIP 309


>UniRef50_Q1GZK2 Cluster: Putative partition-related protein; n=1;
           Methylobacillus flagellatus KT|Rep: Putative
           partition-related protein - Methylobacillus flagellatus
           (strain KT / ATCC 51484 / DSM 6875)
          Length = 210

 Score = 31.9 bits (69), Expect = 9.4
 Identities = 20/54 (37%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
 Frame = +3

Query: 240 TPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPR-EPGMTRDDL 398
           T  ++AD + V++PA + G K    L  A+KDAD++++P      + G TRD L
Sbjct: 68  TNSLSADWTIVDSPAGLRGDK----LKQAVKDADLILVPMQPSAFDMGATRDFL 117


>UniRef50_Q47706 Cluster: Membrane-associated protein uidC
           precursor; n=22; Enterobacteriaceae|Rep:
           Membrane-associated protein uidC precursor - Escherichia
           coli (strain K12)
          Length = 421

 Score = 31.9 bits (69), Expect = 9.4
 Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
 Frame = +1

Query: 76  PLLYKMVQRTFPPHHRGTLKWWSLVPPVVSASLWPFY*SRI-LW 204
           PL+    QRT P    G L +W+L P +    LW  + SR+ LW
Sbjct: 141 PLMAGSSQRTLPTVSEGALGYWALTPNI---DLWGMWRSRVFLW 181


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 531,479,061
Number of Sequences: 1657284
Number of extensions: 10945802
Number of successful extensions: 30129
Number of sequences better than 10.0: 142
Number of HSP's better than 10.0 without gapping: 28958
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 30083
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 33455602480
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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