Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV30037
(585 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P26267 Cluster: Pyruvate dehydrogenase E1 component sub... 163 4e-39
UniRef50_UPI0000E4A5CB Cluster: PREDICTED: hypothetical protein,... 146 3e-34
UniRef50_Q9W4H4 Cluster: CG7024-PA; n=2; Sophophora|Rep: CG7024-... 145 8e-34
UniRef50_Q6NX32 Cluster: Pyruvate dehydrogenase (Lipoamide) alph... 143 2e-33
UniRef50_P08559 Cluster: Pyruvate dehydrogenase E1 component sub... 138 7e-32
UniRef50_Q4T3C0 Cluster: Chromosome undetermined SCAF10102, whol... 119 4e-26
UniRef50_Q23KL2 Cluster: Pyruvate dehydrogenase E1 component; n=... 105 6e-22
UniRef50_P16387 Cluster: Pyruvate dehydrogenase E1 component sub... 105 8e-22
UniRef50_Q9R9N5 Cluster: Pyruvate dehydrogenase E1 component sub... 103 2e-21
UniRef50_Q8H1Y0 Cluster: Pyruvate dehydrogenase E1 component sub... 102 7e-21
UniRef50_A2QWB4 Cluster: Catalytic activity: Pyruvate + Lipoamid... 100 2e-20
UniRef50_Q1EGI2 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 95 1e-18
UniRef50_Q1EGH8 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 93 6e-18
UniRef50_O96865 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 88 2e-16
UniRef50_Q4WHM5 Cluster: Pyruvate dehydrogenase E1 component alp... 87 3e-16
UniRef50_O66112 Cluster: Pyruvate dehydrogenase E1 component sub... 87 3e-16
UniRef50_Q5FNM5 Cluster: Pyruvate dehydrogenase E1 component alp... 86 7e-16
UniRef50_Q4QDQ1 Cluster: Pyruvate dehydrogenase E1 component alp... 84 2e-15
UniRef50_A6DTS3 Cluster: Dehydrogenase complex, E1 component, al... 83 5e-15
UniRef50_A7CXZ4 Cluster: Pyruvate dehydrogenase; n=1; Opitutacea... 83 6e-15
UniRef50_Q12FH4 Cluster: Pyruvate dehydrogenase; n=37; Bacteria|... 80 4e-14
UniRef50_Q74AD3 Cluster: Dehydrogenase complex, E1 component, al... 79 1e-13
UniRef50_Q8SQM8 Cluster: PYRUVATE DEHYDROGENASE E1 COMPONENT ALP... 79 1e-13
UniRef50_Q1ATM5 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacte... 78 1e-13
UniRef50_A6GG24 Cluster: Pyruvate dehydrogenase (Lipoamide), alp... 75 1e-12
UniRef50_A5UU15 Cluster: Pyruvate dehydrogenase; n=3; Chloroflex... 74 2e-12
UniRef50_Q2S150 Cluster: Pyruvate dehydrogenase E1 component, al... 73 4e-12
UniRef50_A0LSF3 Cluster: Pyruvate dehydrogenase; n=5; Bacteria|R... 69 1e-10
UniRef50_A0LTQ9 Cluster: Pyruvate dehydrogenase; n=1; Acidotherm... 68 1e-10
UniRef50_Q1XDM0 Cluster: Pyruvate dehydrogenase E1 component sub... 67 3e-10
UniRef50_A3VIE7 Cluster: Tpp-dependent acetoin dehydrogenase e1 ... 66 6e-10
UniRef50_A7BPK6 Cluster: Pyruvate dehydrogenase; n=1; Beggiatoa ... 65 1e-09
UniRef50_Q1KSF1 Cluster: Apicoplast pyruvate dehydrogenase E1 al... 65 1e-09
UniRef50_A0HHH5 Cluster: Dehydrogenase, E1 component; n=2; Bacte... 65 1e-09
UniRef50_A5V540 Cluster: Dehydrogenase, E1 component; n=3; Prote... 64 2e-09
UniRef50_Q9Z8N4 Cluster: Pyruvate Dehydrogenase Alpha; n=8; Chla... 64 3e-09
UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8; Bacter... 64 3e-09
UniRef50_Q5VGY4 Cluster: Pyruvate dehydrogenase alpha subunit; n... 63 5e-09
UniRef50_Q1ARM0 Cluster: Pyruvate dehydrogenase; n=3; Bacteria|R... 62 7e-09
UniRef50_Q95VS6 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 61 2e-08
UniRef50_A3CMZ3 Cluster: Pyruvate dehydrogenase, TPP-dependent E... 61 2e-08
UniRef50_A4VXG8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 60 5e-08
UniRef50_Q13GQ3 Cluster: Putative 2-oxo acid dehydrogenase alpha... 59 7e-08
UniRef50_Q97YF6 Cluster: Pyruvate dehydrogenase, alpha subunit (... 59 7e-08
UniRef50_Q3J9C5 Cluster: Dehydrogenase, E1 component; n=3; Prote... 59 9e-08
UniRef50_Q83X26 Cluster: Probable pyruvate dehydrogenase alpha-s... 59 9e-08
UniRef50_Q6MAE2 Cluster: Putative pyruvate dehydrogenase (Lipoam... 58 1e-07
UniRef50_A4AFX0 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 58 1e-07
UniRef50_A4X7T3 Cluster: Dehydrogenase, E1 component; n=3; Actin... 58 2e-07
UniRef50_Q3DZ88 Cluster: Dehydrogenase, E1 component; n=1; Chlor... 56 6e-07
UniRef50_Q0LRY7 Cluster: Dehydrogenase, E1 component:Transketola... 54 2e-06
UniRef50_A5V557 Cluster: Pyruvate dehydrogenase; n=1; Sphingomon... 54 2e-06
UniRef50_P27745 Cluster: Acetoin:2,6-dichlorophenolindophenol ox... 54 2e-06
UniRef50_Q7V0M7 Cluster: Dehydrogenase, E1 component; n=1; Proch... 54 2e-06
UniRef50_Q2ITF8 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 53 4e-06
UniRef50_Q2BFQ9 Cluster: Putative uncharacterized protein; n=1; ... 52 8e-06
UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component bet... 51 2e-05
UniRef50_Q98FT3 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 50 3e-05
UniRef50_Q479Q2 Cluster: Dehydrogenase, E1 component; n=2; Rhodo... 50 3e-05
UniRef50_A0LFE6 Cluster: Pyruvate dehydrogenase; n=1; Syntrophob... 50 3e-05
UniRef50_Q18CB6 Cluster: Acetoin:2,6-dichlorophenolindophenol ox... 49 7e-05
UniRef50_Q1NYL5 Cluster: Pyruvate dehydrogenase E1 component alp... 49 9e-05
UniRef50_A0JUQ5 Cluster: Pyruvate dehydrogenase; n=4; Actinobact... 48 1e-04
UniRef50_A0UXT3 Cluster: Pyruvate dehydrogenase; n=1; Clostridiu... 48 2e-04
UniRef50_Q2WB98 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 47 4e-04
UniRef50_Q0MX87 Cluster: Acetoin dehydrogenase alpha-subunit; n=... 47 4e-04
UniRef50_Q53610 Cluster: Branched-chain alpha-keto acid dehydrog... 46 5e-04
UniRef50_Q6A611 Cluster: Pyruvate dehydrogenase E1 component, al... 46 7e-04
UniRef50_A6UDY5 Cluster: Dehydrogenase E1 component; n=2; Alphap... 46 7e-04
UniRef50_A6Q3I6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 46 9e-04
UniRef50_Q748I3 Cluster: Dehydrogenase, E1 component, alpha and ... 45 0.001
UniRef50_A6CP23 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 45 0.001
UniRef50_A7HBV0 Cluster: 3-methyl-2-oxobutanoate dehydrogenase; ... 45 0.002
UniRef50_A6WG12 Cluster: Pyruvate dehydrogenase; n=3; Actinomyce... 44 0.002
UniRef50_A5U0N1 Cluster: Dehydrogenase E1 component; n=7; Mycoba... 44 0.002
UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 44 0.003
UniRef50_Q67SE7 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 44 0.003
UniRef50_Q319T4 Cluster: Pyruvate dehydrogenase; n=1; Prochloroc... 44 0.004
UniRef50_Q0ET31 Cluster: Dehydrogenase, E1 component; n=1; Therm... 42 0.008
UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3; Bac... 42 0.008
UniRef50_A4XF89 Cluster: Dehydrogenase, E1 component; n=1; Novos... 42 0.008
UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta sub... 42 0.008
UniRef50_Q9HN77 Cluster: Pyruvate dehydrogenase alpha subunit; n... 41 0.019
UniRef50_Q7N3C2 Cluster: Similar to 3-methyl-2-oxobutanoate dehy... 40 0.033
UniRef50_Q11G20 Cluster: Twin-arginine translocation pathway sig... 40 0.033
UniRef50_Q8U4T5 Cluster: 2-oxo acid dehydrogenase subunit E1; n=... 40 0.033
UniRef50_A3RZM3 Cluster: Pyruvate dehydrogenase E1 component alp... 40 0.043
UniRef50_Q83DQ6 Cluster: Dehydrogenase, E1 component, alpha subu... 39 0.100
UniRef50_Q02C52 Cluster: Pyruvate dehydrogenase; n=1; Solibacter... 39 0.100
UniRef50_Q5SJR9 Cluster: Pyruvate dehydrogenase (Lipoamide) (EC ... 38 0.13
UniRef50_Q1LFS5 Cluster: Dehydrogenase, E1 component; n=22; Prot... 38 0.13
UniRef50_UPI00005103B4 Cluster: COG1071: Pyruvate/2-oxoglutarate... 38 0.23
UniRef50_Q93N50 Cluster: Pyruvate dehydrogenase alpha subunit; n... 37 0.30
UniRef50_Q6YPX5 Cluster: Thiamine pyrophosphate-dependent dehydr... 37 0.30
UniRef50_UPI0000384B37 Cluster: COG1071: Pyruvate/2-oxoglutarate... 37 0.40
UniRef50_Q9K3H0 Cluster: Putative pyruvate dehydrogenase alpha s... 37 0.40
UniRef50_A0K283 Cluster: Pyruvate dehydrogenase; n=4; Actinobact... 37 0.40
UniRef50_Q2J998 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp... 36 0.53
UniRef50_Q3WCG3 Cluster: Pyruvate dehydrogenase; n=4; Actinomyce... 36 0.53
UniRef50_UPI00004D6EAE Cluster: Ras and Rab interactor 1 (Ras in... 36 0.70
UniRef50_Q8CX87 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 36 0.70
UniRef50_Q83FF2 Cluster: Pyruvate dehydrogenase E1 component alp... 36 0.93
UniRef50_A7D3P2 Cluster: Pyruvate dehydrogenase; n=1; Halorubrum... 36 0.93
UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 35 1.6
UniRef50_A3DC57 Cluster: Methyl-accepting chemotaxis sensory tra... 34 2.2
UniRef50_A0QB51 Cluster: Dehydrogenase E1 component superfamily ... 34 2.8
UniRef50_A2FVJ6 Cluster: DnaK protein; n=1; Trichomonas vaginali... 34 2.8
UniRef50_UPI0000F2D933 Cluster: PREDICTED: similar to doublecort... 33 3.8
UniRef50_Q3W421 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp... 33 3.8
UniRef50_Q5KGR5 Cluster: Branched-chain alpha-keto acid dehydrog... 33 3.8
UniRef50_Q6QXE3 Cluster: ORF24; n=1; Agrotis segetum granuloviru... 33 6.6
UniRef50_A2DM79 Cluster: Putative uncharacterized protein; n=1; ... 33 6.6
UniRef50_Q0RLC2 Cluster: Pyruvate dehydrogenase E1 component, al... 32 8.7
>UniRef50_P26267 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha type I, mitochondrial precursor; n=10;
cellular organisms|Rep: Pyruvate dehydrogenase E1
component subunit alpha type I, mitochondrial precursor
- Ascaris suum (Pig roundworm) (Ascaris lumbricoides)
Length = 396
Score = 163 bits (395), Expect = 4e-39
Identities = 76/131 (58%), Positives = 97/131 (74%)
Frame = +3
Query: 189 ITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRR 368
+ V+ V+A + + ++ EATF+ KP+KLHKLD GP + +T EDA+ Y Q+ +RR
Sbjct: 11 VPTVSPSVMAISVRLAST-EATFQTKPFKLHKLDSGPDINVHVTKEDAVHYYTQMLTIRR 69
Query: 369 IETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLG 548
+E+A+GNLYKEK +RGFCHLYSGQEA AVG +AAM D+ +TAYRCHGWTYL G SV
Sbjct: 70 MESAAGNLYKEKKVRGFCHLYSGQEACAVGTKAAMDAGDAAVTAYRCHGWTYLSGSSVAK 129
Query: 549 VLSELTGRRTG 581
VL ELTGR TG
Sbjct: 130 VLCELTGRITG 140
>UniRef50_UPI0000E4A5CB Cluster: PREDICTED: hypothetical protein,
partial; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein, partial -
Strongylocentrotus purpuratus
Length = 378
Score = 146 bits (355), Expect = 3e-34
Identities = 63/106 (59%), Positives = 83/106 (78%)
Frame = +3
Query: 267 PYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEA 446
P+KLHKL++GP ++ LT ++AL Y ++ +RR+ETA+ LYK K +RGFCHLYSGQEA
Sbjct: 165 PFKLHKLEEGPKKTSVLTKDEALDYYHKMQTIRRMETAAATLYKSKEVRGFCHLYSGQEA 224
Query: 447 VAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
AVG+ + + D+VITAYR HGW YL GV++ GVL+ELTGRRTGC
Sbjct: 225 CAVGISSVLTPDDAVITAYRAHGWAYLRGVTLHGVLAELTGRRTGC 270
>UniRef50_Q9W4H4 Cluster: CG7024-PA; n=2; Sophophora|Rep: CG7024-PA
- Drosophila melanogaster (Fruit fly)
Length = 479
Score = 145 bits (351), Expect = 8e-34
Identities = 64/105 (60%), Positives = 79/105 (75%)
Frame = +3
Query: 270 YKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAV 449
+K + L+ GP L+ EDAL +Y Q+ LRR ET +GN YKE+ IRGFCHLY+GQEAV
Sbjct: 43 FKCYDLENGPTMDVELSREDALTMYTQMLELRRFETVAGNYYKERKIRGFCHLYNGQEAV 102
Query: 450 AVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
AVGM+ +R DSVITAYRCH WTYLMGVS+ +++EL G RTGC
Sbjct: 103 AVGMKQRLRSCDSVITAYRCHAWTYLMGVSLYEIMAELFGVRTGC 147
>UniRef50_Q6NX32 Cluster: Pyruvate dehydrogenase (Lipoamide) alpha
1; n=3; Tetrapoda|Rep: Pyruvate dehydrogenase
(Lipoamide) alpha 1 - Xenopus tropicalis (Western clawed
frog) (Silurana tropicalis)
Length = 369
Score = 143 bits (347), Expect = 2e-33
Identities = 68/152 (44%), Positives = 95/152 (62%)
Frame = +3
Query: 129 IIDKMSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATS 308
++ +S+++ A+ + +VA+ EATF+IK +H+L++GP T
Sbjct: 4 MLSLLSRVLKGPAQKPVTGAANEAVRVMVASRNYADFASEATFDIKKCDVHRLEEGPPTQ 63
Query: 309 ATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADS 488
A LT E L+ Y + +RR+E S LYK+KIIRGFCHLY GQEA VG+ AA+ D
Sbjct: 64 AVLTREQGLQYYRTMQTIRRMELKSDQLYKQKIIRGFCHLYDGQEACCVGLEAAINPTDH 123
Query: 489 VITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
+ITAYR HG++Y GVSV +L+ELTGRR GC
Sbjct: 124 LITAYRAHGYSYTRGVSVKEILAELTGRRGGC 155
>UniRef50_P08559 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha, somatic form, mitochondrial precursor;
n=110; cellular organisms|Rep: Pyruvate dehydrogenase E1
component subunit alpha, somatic form, mitochondrial
precursor - Homo sapiens (Human)
Length = 390
Score = 138 bits (335), Expect = 7e-32
Identities = 66/148 (44%), Positives = 96/148 (64%)
Frame = +3
Query: 141 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 320
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 321 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 500
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 501 YRCHGWTYLMGVSVLGVLSELTGRRTGC 584
YR HG+T+ G+SV +L+ELTGR+ GC
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGC 145
>UniRef50_Q4T3C0 Cluster: Chromosome undetermined SCAF10102, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF10102,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 491
Score = 119 bits (287), Expect = 4e-26
Identities = 54/102 (52%), Positives = 71/102 (69%)
Frame = +3
Query: 276 LHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAV 455
LH+L++GP A LT E L+ Y + +RR+E + LYK+KIIRGFCHLY GQEA A
Sbjct: 5 LHRLEEGPPEKAELTREQGLQYYRTMQTIRRMELKADQLYKQKIIRGFCHLYDGQEACAA 64
Query: 456 GMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
G+ AA+ +D +ITAYR HG+T+ GVSV +L+ELTG G
Sbjct: 65 GIEAAITPSDHLITAYRAHGYTFTRGVSVKEILAELTGETGG 106
>UniRef50_Q23KL2 Cluster: Pyruvate dehydrogenase E1 component; n=5;
Intramacronucleata|Rep: Pyruvate dehydrogenase E1
component - Tetrahymena thermophila SB210
Length = 429
Score = 105 bits (253), Expect = 6e-22
Identities = 56/140 (40%), Positives = 78/140 (55%), Gaps = 1/140 (0%)
Frame = +3
Query: 165 AKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPA-TSATLTSEDALKL 341
AK + V KY+ T ++ Y+ LD T +T T E+ LKL
Sbjct: 41 AKLMISKFFNPVAGKTFNRLNKYAFSS-VTINLEGYQTKMLDGFKLPTQSTATKEELLKL 99
Query: 342 YEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWT 521
Y+ + ++R+IE A LYK++ IRGFCHLY GQEAV G+ AA D++ITAYRCH
Sbjct: 100 YKDMNVMRKIELACDKLYKQREIRGFCHLYDGQEAVISGIEAACNLEDAIITAYRCHCHA 159
Query: 522 YLMGVSVLGVLSELTGRRTG 581
Y G + +++EL GR+TG
Sbjct: 160 YTRGDTPHQIIAELMGRKTG 179
>UniRef50_P16387 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha, mitochondrial precursor; n=34;
Dikarya|Rep: Pyruvate dehydrogenase E1 component subunit
alpha, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 420
Score = 105 bits (252), Expect = 8e-22
Identities = 49/95 (51%), Positives = 65/95 (68%)
Frame = +3
Query: 297 PATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 476
P S + L++Y+ + I+RR+E A LYK K IRGFCHL GQEA+AVG+ A+
Sbjct: 70 PDLSYETSKATLLQMYKDMVIIRRMEMACDALYKAKKIRGFCHLSVGQEAIAVGIENAIT 129
Query: 477 DADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
DS+IT+YRCHG+T++ G SV VL+EL GRR G
Sbjct: 130 KLDSIITSYRCHGFTFMRGASVKAVLAELMGRRAG 164
>UniRef50_Q9R9N5 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=62; Bacteria|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Rhizobium
meliloti (Sinorhizobium meliloti)
Length = 348
Score = 103 bits (248), Expect = 2e-21
Identities = 50/100 (50%), Positives = 63/100 (63%)
Frame = +3
Query: 282 KLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 461
K D T A + ED LK Y ++ ++RR E +G LY I GFCHLY GQEAV VGM
Sbjct: 20 KKDFAGGTIAEFSKEDDLKAYREMLLIRRFEEKAGQLYGMGFIGGFCHLYIGQEAVVVGM 79
Query: 462 RAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
+ A+++ D VIT YR HG G+S GV++ELTGRR G
Sbjct: 80 QLALKEGDQVITGYRDHGHMLACGMSARGVMAELTGRRGG 119
>UniRef50_Q8H1Y0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha-2, mitochondrial precursor; n=33; cellular
organisms|Rep: Pyruvate dehydrogenase E1 component
subunit alpha-2, mitochondrial precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 393
Score = 102 bits (244), Expect = 7e-21
Identities = 49/106 (46%), Positives = 69/106 (65%)
Frame = +3
Query: 267 PYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEA 446
P+ H L + P+ S +SE+ L + + +RR+E A+ +LYK K+IRGFCHLY GQEA
Sbjct: 43 PFTSH-LCESPSRSVETSSEEILAFFRDMARMRRMEIAADSLYKAKLIRGFCHLYDGQEA 101
Query: 447 VAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
+AVGM AA+ D++IT+YR H G ++ SEL GR+TGC
Sbjct: 102 LAVGMEAAITKKDAIITSYRDHCTFIGRGGKLVDAFSELMGRKTGC 147
>UniRef50_A2QWB4 Cluster: Catalytic activity: Pyruvate + Lipoamide
<=> S-Acetyldihydrolipoamide + CO2; n=3; Ascomycota|Rep:
Catalytic activity: Pyruvate + Lipoamide <=>
S-Acetyldihydrolipoamide + CO2 - Aspergillus niger
Length = 403
Score = 100 bits (240), Expect = 2e-20
Identities = 49/104 (47%), Positives = 68/104 (65%)
Frame = +3
Query: 270 YKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAV 449
++ + LD P + T T +LY ++++RR+E A+ LYKE+ IRGFCHL +GQEAV
Sbjct: 54 FETYNLDPPPYSLET-TKSQLKQLYYDMSLIRRMELAADKLYKEQKIRGFCHLSTGQEAV 112
Query: 450 AVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
AVG+ + D VITAYR HG+T + G SV ++ EL GRR G
Sbjct: 113 AVGVEHGISPEDKVITAYRAHGFTLMRGGSVKSIIGELLGRRDG 156
>UniRef50_Q1EGI2 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=6; Spirotrichea|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Euplotes sp. BB-2004
Length = 389
Score = 94.7 bits (225), Expect = 1e-18
Identities = 44/109 (40%), Positives = 66/109 (60%), Gaps = 1/109 (0%)
Frame = +3
Query: 258 EIKPYKLHKLDQGPA-TSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYS 434
E+ +K+H++++ T AT T + L Y+ + ++RR+E S LYK K IRGFCHLY
Sbjct: 30 ELPKFKVHRIEESELPTKATTTKSELLNYYKDMALMRRVEIVSDMLYKNKWIRGFCHLYD 89
Query: 435 GQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
GQE++ VGM AA+ D +I AYR H G + +++E+ R TG
Sbjct: 90 GQESITVGMEAALTMEDHIINAYRDHTTAMGRGHTSYEIIAEMMQRSTG 138
>UniRef50_Q1EGH8 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=1; Nyctotherus ovalis|Rep: Pyruvate dehydrogenase E1
alpha subunit - Nyctotherus ovalis
Length = 136
Score = 92.7 bits (220), Expect = 6e-18
Identities = 44/125 (35%), Positives = 74/125 (59%), Gaps = 1/125 (0%)
Frame = +3
Query: 210 VVATNAKYSTKKEATFEIKPYKLHKLDQGPA-TSATLTSEDALKLYEQLTILRRIETASG 386
++ ++A++++ E ++ Y++ LD+ T A ++ LK Y + RR+E
Sbjct: 11 IIGSSARFASTVE--IKLPQYEVFNLDKSILPTKAQTNRDEMLKYYHDMNFQRRVEIMCD 68
Query: 387 NLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELT 566
+YK+K +RGFCHL GQEAV+VG+ A + D +ITAYRCHG G + +++E+
Sbjct: 69 EIYKKKEVRGFCHLMDGQEAVSVGVEAGITKEDHLITAYRCHGVLLGRGETAARLIAEMM 128
Query: 567 GRRTG 581
G+ TG
Sbjct: 129 GKATG 133
>UniRef50_O96865 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Trypanosoma cruzi|Rep: Pyruvate dehydrogenase E1
alpha subunit - Trypanosoma cruzi
Length = 378
Score = 87.8 bits (208), Expect = 2e-16
Identities = 47/111 (42%), Positives = 63/111 (56%), Gaps = 4/111 (3%)
Frame = +3
Query: 264 KPYKLHKL---DQGPA-TSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLY 431
KP+KLH D P T+AT +E K E + +RR+E+ YK K IRGFCHLY
Sbjct: 21 KPFKLHTAGRDDVPPVPTTATYDTEQMKKCLEMMFRIRRMESLCDQSYKLKKIRGFCHLY 80
Query: 432 SGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
GQEA+ VGM + D ++TAYR H W + G + V +E+ G+ GC
Sbjct: 81 IGQEAIPVGMENVLTLEDLIVTAYRDHAWYIVRGGTPGEVFAEMFGKEGGC 131
>UniRef50_Q4WHM5 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit, putative; n=1; Aspergillus fumigatus|Rep:
Pyruvate dehydrogenase E1 component alpha subunit,
putative - Aspergillus fumigatus (Sartorya fumigata)
Length = 360
Score = 87.0 bits (206), Expect = 3e-16
Identities = 38/73 (52%), Positives = 54/73 (73%)
Frame = +3
Query: 363 RRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSV 542
+R+E A+ LYK+K IRGFCHL +GQEAVAVG+ + D +ITAYR HG+T++ G S+
Sbjct: 81 QRLEIAADALYKQKKIRGFCHLSTGQEAVAVGIEYGISKEDKLITAYRSHGFTFMRGGSI 140
Query: 543 LGVLSELTGRRTG 581
+ ++ EL GR+ G
Sbjct: 141 MSIVGELLGRQDG 153
>UniRef50_O66112 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=38; Proteobacteria|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Zymomonas
mobilis
Length = 354
Score = 87.0 bits (206), Expect = 3e-16
Identities = 43/87 (49%), Positives = 58/87 (66%), Gaps = 1/87 (1%)
Frame = +3
Query: 324 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDA-DSVITA 500
E+ L+ Y ++ ++RR E G LY +I GFCHLY GQEAVAVG++AA++ DSVIT
Sbjct: 37 EELLEFYRRMLMIRRFEERCGQLYGLGLIAGFCHLYIGQEAVAVGLQAALQPGRDSVITG 96
Query: 501 YRCHGWTYLMGVSVLGVLSELTGRRTG 581
YR HG G+ V++ELTGR +G
Sbjct: 97 YREHGHMLAYGIDPKIVMAELTGRASG 123
>UniRef50_Q5FNM5 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=4; Bacteria|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Gluconobacter oxydans
(Gluconobacter suboxydans)
Length = 334
Score = 85.8 bits (203), Expect = 7e-16
Identities = 41/96 (42%), Positives = 57/96 (59%)
Frame = +3
Query: 294 GPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAM 473
G + L+ E + Y + ++RR E +G LY +I GFCHLY GQEAV VG+ M
Sbjct: 9 GRSNGPALSPETMKRAYRDMLLVRRFEEKAGQLYGMGLIGGFCHLYIGQEAVVVGIGLNM 68
Query: 474 RDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
+ D IT+YR HG + G++ GV++ELTGR G
Sbjct: 69 KQGDKSITSYRDHGQMLVAGMTPRGVMAELTGRSGG 104
>UniRef50_Q4QDQ1 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit, putative; n=5; Euglenozoa|Rep: Pyruvate
dehydrogenase E1 component alpha subunit, putative -
Leishmania major
Length = 378
Score = 84.2 bits (199), Expect = 2e-15
Identities = 48/127 (37%), Positives = 63/127 (49%), Gaps = 4/127 (3%)
Frame = +3
Query: 216 ATNAKYSTKKEATFEIKPYKLH---KLDQGPATSATLTSEDALKLYEQLTI-LRRIETAS 383
AT TK +P+KLH + D P + + + LK L +RR+E+
Sbjct: 5 ATRCLLDTKTVPLKPQRPFKLHTAGRTDMAPLPTQAVYDAEQLKQSLALMFRIRRMESLC 64
Query: 384 GNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSEL 563
YK K IRGFCHLY GQEA+ GM + D +IT YR HGW G V +E+
Sbjct: 65 DQSYKLKKIRGFCHLYIGQEAIPAGMENVLTFEDPIITGYRDHGWYISRGGKPEDVFAEM 124
Query: 564 TGRRTGC 584
GR+ GC
Sbjct: 125 FGRQGGC 131
>UniRef50_A6DTS3 Cluster: Dehydrogenase complex, E1 component, alpha
subunit; n=1; Lentisphaera araneosa HTCC2155|Rep:
Dehydrogenase complex, E1 component, alpha subunit -
Lentisphaera araneosa HTCC2155
Length = 320
Score = 83.0 bits (196), Expect = 5e-15
Identities = 38/87 (43%), Positives = 55/87 (63%)
Frame = +3
Query: 324 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 503
E AL++ EQ+ +RR E Y++K I GFCH Y GQEAVAVG A + D+ +T+Y
Sbjct: 7 EKALQMLEQMIRVRRFEEGCLKSYQQKFITGFCHTYIGQEAVAVGAMAHLTPTDAYVTSY 66
Query: 504 RCHGWTYLMGVSVLGVLSELTGRRTGC 584
RCH + G++ V++E+ G+ TGC
Sbjct: 67 RCHAQGLIGGLTSREVMAEMFGKITGC 93
>UniRef50_A7CXZ4 Cluster: Pyruvate dehydrogenase; n=1; Opitutaceae
bacterium TAV2|Rep: Pyruvate dehydrogenase - Opitutaceae
bacterium TAV2
Length = 365
Score = 82.6 bits (195), Expect = 6e-15
Identities = 42/93 (45%), Positives = 56/93 (60%)
Frame = +3
Query: 306 SATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDAD 485
+A LT ++LY + +RR E S Y+ K I GF HLY GQEAVAVG + M + D
Sbjct: 28 NADLTPAARIELYRTMVRIRRFEERSLRAYQAKKIGGFLHLYIGQEAVAVGCCSLMGEHD 87
Query: 486 SVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
VITAYR HG +G+ +++EL G+ TGC
Sbjct: 88 HVITAYRDHGHAIAVGMDTKALMAELYGKATGC 120
>UniRef50_Q12FH4 Cluster: Pyruvate dehydrogenase; n=37;
Bacteria|Rep: Pyruvate dehydrogenase - Polaromonas sp.
(strain JS666 / ATCC BAA-500)
Length = 337
Score = 79.8 bits (188), Expect = 4e-14
Identities = 37/85 (43%), Positives = 55/85 (64%)
Frame = +3
Query: 330 ALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRC 509
AL + + +RR+E LY E+ IRGF HLY G+EAVAVG A++ D+V+ YR
Sbjct: 21 ALAVLAGMLRIRRMEEKCAQLYGEQKIRGFLHLYIGEEAVAVGALRALQPQDNVVATYRE 80
Query: 510 HGWTYLMGVSVLGVLSELTGRRTGC 584
HG L G+++ G+++E+ G+R GC
Sbjct: 81 HGHALLRGLAMNGIMAEMYGKREGC 105
>UniRef50_Q74AD3 Cluster: Dehydrogenase complex, E1 component, alpha
subunit; n=5; Geobacter|Rep: Dehydrogenase complex, E1
component, alpha subunit - Geobacter sulfurreducens
Length = 325
Score = 78.6 bits (185), Expect = 1e-13
Identities = 39/91 (42%), Positives = 54/91 (59%)
Frame = +3
Query: 309 ATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADS 488
A L + LK++EQ+ + R E + Y + I GF HLYSGQEAVAVG AA+R D
Sbjct: 7 AILPDSELLKMHEQMVLSREFEESCAEQYTKGHITGFLHLYSGQEAVAVGATAALRKDDY 66
Query: 489 VITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
+++AYR H + G V++EL G+ TG
Sbjct: 67 ILSAYREHAQAIVRGAEPRRVMAELFGKATG 97
>UniRef50_Q8SQM8 Cluster: PYRUVATE DEHYDROGENASE E1 COMPONENT ALPHA
SUBUNIT; n=1; Encephalitozoon cuniculi|Rep: PYRUVATE
DEHYDROGENASE E1 COMPONENT ALPHA SUBUNIT -
Encephalitozoon cuniculi
Length = 349
Score = 78.6 bits (185), Expect = 1e-13
Identities = 35/86 (40%), Positives = 54/86 (62%)
Frame = +3
Query: 324 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 503
+ A+ +Y+Q+ +R ++ A YK K IRGFCHL GQE + + AM D D +++Y
Sbjct: 37 DKAVYIYKQMMRMRCMDEAMDREYKRKNIRGFCHLSIGQEGIYAALEYAM-DGDVAVSSY 95
Query: 504 RCHGWTYLMGVSVLGVLSELTGRRTG 581
RCHG Y+ G S+L ++ E+ GR+ G
Sbjct: 96 RCHGIAYVTGCSILEIMGEVLGRQAG 121
>UniRef50_Q1ATM5 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate dehydrogenase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 353
Score = 78.2 bits (184), Expect = 1e-13
Identities = 40/93 (43%), Positives = 56/93 (60%), Gaps = 1/93 (1%)
Frame = +3
Query: 306 SATLTSEDAL-KLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDA 482
SA TS D L +LY ++ ++R E A +++ I G+ H+Y+GQEAVA G A R+
Sbjct: 19 SAVATSPDRLAELYGKMVLIRAFEDACQRAFRQGKIGGYLHVYTGQEAVATGFLEAFREG 78
Query: 483 DSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
D VIT YR H L+G V++EL G+RTG
Sbjct: 79 DRVITGYRDHAHALLLGCDPKEVMAELFGKRTG 111
>UniRef50_A6GG24 Cluster: Pyruvate dehydrogenase (Lipoamide), alpha
subunit; n=1; Plesiocystis pacifica SIR-1|Rep: Pyruvate
dehydrogenase (Lipoamide), alpha subunit - Plesiocystis
pacifica SIR-1
Length = 339
Score = 74.9 bits (176), Expect = 1e-12
Identities = 35/95 (36%), Positives = 52/95 (54%)
Frame = +3
Query: 297 PATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 476
P T + ++ LK + ++ +RR E + Y I GF HLY GQEA+AVG++ AM+
Sbjct: 11 PETLTSAGKDETLKAFREMLRIRRFEETAARAYTRGKISGFLHLYIGQEAIAVGVKLAMQ 70
Query: 477 DADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
D V+ YR HG+ G ++EL G+ TG
Sbjct: 71 ANDRVVGTYRDHGYALAQGSDANACMAELFGKATG 105
>UniRef50_A5UU15 Cluster: Pyruvate dehydrogenase; n=3; Chloroflexi
(class)|Rep: Pyruvate dehydrogenase - Roseiflexus sp.
RS-1
Length = 350
Score = 74.1 bits (174), Expect = 2e-12
Identities = 35/90 (38%), Positives = 50/90 (55%)
Frame = +3
Query: 315 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 494
L + + Y Q+ ++RR E +Y I GF HLY G+EA AVG AA+R D +
Sbjct: 21 LDAATLIDYYRQMVLIRRFEEKCQEMYTRAKIGGFLHLYIGEEATAVGAIAALRPDDHIF 80
Query: 495 TAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
T YR HG G+ + +++EL G+ TGC
Sbjct: 81 THYRDHGHAIARGLDINALMAELFGKVTGC 110
>UniRef50_Q2S150 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Salinibacter ruber DSM 13855|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit - Salinibacter
ruber (strain DSM 13855)
Length = 470
Score = 73.3 bits (172), Expect = 4e-12
Identities = 40/110 (36%), Positives = 57/110 (51%), Gaps = 1/110 (0%)
Frame = +3
Query: 258 EIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSG 437
E Y+ + D + ++ L L + + RR E +Y+ + I GF HLY G
Sbjct: 126 ETVTYETYPADTYGHDELGIADDEVLDLLRNMLLQRRFENRCRQMYQRQKISGFLHLYIG 185
Query: 438 QEAVAVG-MRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
QEAV+ G + A DSVITAYR HG MG++ ++EL G+ TGC
Sbjct: 186 QEAVSTGSVNAIELGDDSVITAYRDHGMGLAMGITPEAGMAELFGKETGC 235
>UniRef50_A0LSF3 Cluster: Pyruvate dehydrogenase; n=5; Bacteria|Rep:
Pyruvate dehydrogenase - Acidothermus cellulolyticus
(strain ATCC 43068 / 11B)
Length = 375
Score = 68.5 bits (160), Expect = 1e-10
Identities = 35/96 (36%), Positives = 50/96 (52%), Gaps = 1/96 (1%)
Frame = +3
Query: 297 PATSATLTSEDALKLY-EQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAM 473
PA D L+ Y + ++RR E + +Y+ I G+CHL G+EA VG+ AM
Sbjct: 29 PADRLAQEPPDKLRAYYRMMQLIRRFEERAAEMYQRAKIGGYCHLNLGEEATVVGLMDAM 88
Query: 474 RDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
D + T YR HG+ G+ V++EL GR TG
Sbjct: 89 APHDYLFTTYREHGYALARGIDPGRVMAELFGRTTG 124
>UniRef50_A0LTQ9 Cluster: Pyruvate dehydrogenase; n=1; Acidothermus
cellulolyticus 11B|Rep: Pyruvate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 342
Score = 68.1 bits (159), Expect = 1e-10
Identities = 37/99 (37%), Positives = 52/99 (52%)
Frame = +3
Query: 285 LDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMR 464
L + P +A + + L L+E + LR E + +L+ + +++G HL GQEAVA G
Sbjct: 9 LPERPTFTAEVNGRE-LDLFELMVRLRFFERRAHDLFLQGLVKGTSHLSLGQEAVATGFA 67
Query: 465 AAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
AAM D YR H T G S+ GV+ EL GR G
Sbjct: 68 AAMEPTDLTFATYRGHAHTLSRGASMTGVMGELMGRSVG 106
>UniRef50_Q1XDM0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=52; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Porphyra
yezoensis
Length = 346
Score = 66.9 bits (156), Expect = 3e-10
Identities = 34/95 (35%), Positives = 49/95 (51%)
Frame = +3
Query: 300 ATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRD 479
+T L + L LYE + + R E +Y + + GF HLY+GQEAV+ G+ +
Sbjct: 16 STGLNLNKSNLLVLYEDMLLGRNFEDMCAQMYYKGKMFGFVHLYNGQEAVSTGVIKLLNP 75
Query: 480 ADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
D V + YR H GV V++EL G+ TGC
Sbjct: 76 TDYVCSTYRDHVHALSKGVPSKNVMAELFGKETGC 110
>UniRef50_A3VIE7 Cluster: Tpp-dependent acetoin dehydrogenase e1
alpha-subunit; n=2; Rhodobacterales|Rep: Tpp-dependent
acetoin dehydrogenase e1 alpha-subunit - Rhodobacterales
bacterium HTCC2654
Length = 335
Score = 66.1 bits (154), Expect = 6e-10
Identities = 36/101 (35%), Positives = 52/101 (51%)
Frame = +3
Query: 279 HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 458
H + A S T T ED L++Y Q+ +R E + LY + G H+YSG+EAVAVG
Sbjct: 5 HLREDTMAKSKTNT-EDYLRMYRQMVRIRTFEDNANQLYLSAKMPGLTHMYSGEEAVAVG 63
Query: 459 MRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
+ A+ D D + + +R HG G + EL G+ G
Sbjct: 64 ICEALTDDDRITSTHRGHGHCVAKGAEFKEMFCELLGKEEG 104
>UniRef50_A7BPK6 Cluster: Pyruvate dehydrogenase; n=1; Beggiatoa sp.
PS|Rep: Pyruvate dehydrogenase - Beggiatoa sp. PS
Length = 331
Score = 65.3 bits (152), Expect = 1e-09
Identities = 31/87 (35%), Positives = 50/87 (57%)
Frame = +3
Query: 324 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 503
E+ L Y L ++RR+E A Y E+ +R HL GQEAVAVG+ ++ +D + +++
Sbjct: 14 EELLTFYRSLLLIRRVEEAIAERYTEQEMRCPTHLCIGQEAVAVGVCKMLQQSDGIFSSH 73
Query: 504 RCHGWTYLMGVSVLGVLSELTGRRTGC 584
R H G + +++EL G+ TGC
Sbjct: 74 RAHSHYLAKGGDLKAMIAELYGKSTGC 100
>UniRef50_Q1KSF1 Cluster: Apicoplast pyruvate dehydrogenase E1 alpha
subunit; n=1; Toxoplasma gondii|Rep: Apicoplast pyruvate
dehydrogenase E1 alpha subunit - Toxoplasma gondii
Length = 635
Score = 65.3 bits (152), Expect = 1e-09
Identities = 34/82 (41%), Positives = 46/82 (56%)
Frame = +3
Query: 339 LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGW 518
L E + R +E A LY GF HLY+GQEAV+ G+ +R D+V++ YR H
Sbjct: 261 LLEDMLTGRMVEDACARLYYMGKTAGFVHLYTGQEAVSAGVIKLLRPDDAVVSTYRDHVH 320
Query: 519 TYLMGVSVLGVLSELTGRRTGC 584
GV V V++EL G+ TGC
Sbjct: 321 ATSKGVPVREVMAELFGKATGC 342
>UniRef50_A0HHH5 Cluster: Dehydrogenase, E1 component; n=2;
Bacteria|Rep: Dehydrogenase, E1 component - Comamonas
testosteroni KF-1
Length = 327
Score = 64.9 bits (151), Expect = 1e-09
Identities = 34/84 (40%), Positives = 46/84 (54%)
Frame = +3
Query: 330 ALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRC 509
A +L EQ+ +R +E +L K I+G HL GQEA+ G AA + D V + YR
Sbjct: 16 AKELLEQMIRIRLLEEKIADLRKSGEIQGSVHLCIGQEAIYSGSCAARQPGDRVFSTYRG 75
Query: 510 HGWTYLMGVSVLGVLSELTGRRTG 581
HGW + GV +L+EL R TG
Sbjct: 76 HGWAHACGVPAEAILAELLARETG 99
>UniRef50_A5V540 Cluster: Dehydrogenase, E1 component; n=3;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Sphingomonas wittichii RW1
Length = 334
Score = 64.1 bits (149), Expect = 2e-09
Identities = 31/97 (31%), Positives = 52/97 (53%)
Frame = +3
Query: 291 QGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAA 470
+G A + + ++LY ++ +R E + G L+ I GF HL GQE V+VG+ A+
Sbjct: 10 RGAAHGRNARAPELIELYRRMVTIREAEKSCGALFAAGEIPGFIHLSDGQEGVSVGVMAS 69
Query: 471 MRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
+R D++ + +R HG G+ + G EL G+ G
Sbjct: 70 LRADDTIASTHRGHGHALAKGLGLDGFFRELMGKADG 106
>UniRef50_Q9Z8N4 Cluster: Pyruvate Dehydrogenase Alpha; n=8;
Chlamydiaceae|Rep: Pyruvate Dehydrogenase Alpha -
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Length = 342
Score = 63.7 bits (148), Expect = 3e-09
Identities = 29/84 (34%), Positives = 45/84 (53%)
Frame = +3
Query: 333 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 512
+K +Q+ ++R E Y E ++ GF H Y+GQEAVA A V ++YRCH
Sbjct: 32 IKFLKQMVLIREFEARGEEAYLEGLVGGFYHSYAGQEAVATAAIANTGLDPWVFSSYRCH 91
Query: 513 GWTYLMGVSVLGVLSELTGRRTGC 584
L+ + + + +EL G+ TGC
Sbjct: 92 ALAILLNIPLQEIAAELLGKETGC 115
>UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8;
Bacteria|Rep: Dehydrogenase E1 component - Jannaschia
sp. (strain CCS1)
Length = 675
Score = 63.7 bits (148), Expect = 3e-09
Identities = 33/94 (35%), Positives = 50/94 (53%)
Frame = +3
Query: 300 ATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRD 479
AT L +D + + +RR ET + L+ + +I+G H GQEA+A G A +
Sbjct: 13 ATPNGLAPKDLRAALKMMLRIRRFETRAKELFLQGVIKGTAHSSVGQEAIAAGACAVLEP 72
Query: 480 ADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
AD ++T +R HG T G + + +EL GR TG
Sbjct: 73 ADFILTHHRGHGHTIAKGADLGRMFAELMGRETG 106
>UniRef50_Q5VGY4 Cluster: Pyruvate dehydrogenase alpha subunit; n=6;
Plasmodium|Rep: Pyruvate dehydrogenase alpha subunit -
Plasmodium falciparum
Length = 608
Score = 62.9 bits (146), Expect = 5e-09
Identities = 32/93 (34%), Positives = 49/93 (52%)
Frame = +3
Query: 303 TSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDA 482
+ ++ E+ LYE + + R E LY K + GF HLY+GQEAV+ G+ ++++
Sbjct: 184 SDVNISREEICTLYEDMYLGRLFENLVAKLYYNKRVNGFVHLYNGQEAVSTGIIKNLKNS 243
Query: 483 DSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
D V + YR H GV +L+EL G G
Sbjct: 244 DFVTSTYRDHVHALSKGVPAHKILNELYGNYYG 276
>UniRef50_Q1ARM0 Cluster: Pyruvate dehydrogenase; n=3; Bacteria|Rep:
Pyruvate dehydrogenase - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 332
Score = 62.5 bits (145), Expect = 7e-09
Identities = 31/89 (34%), Positives = 48/89 (53%)
Frame = +3
Query: 315 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 494
L E + + + +RR E L+K + GF HLY G+EAVAVG +A+R+ D +
Sbjct: 2 LGEEKLVGMLRLMLRIRRFEEKLAELFKRGKLPGFVHLYIGEEAVAVGACSALREDDRIT 61
Query: 495 TAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
+ +R HG G V +++EL G+ G
Sbjct: 62 STHRGHGHVIAKGADVSRMMAELLGKEAG 90
>UniRef50_Q95VS6 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Antonospora locustae|Rep: Pyruvate dehydrogenase E1
alpha subunit - Antonospora locustae (Nosema locustae)
Length = 342
Score = 61.3 bits (142), Expect = 2e-08
Identities = 31/92 (33%), Positives = 47/92 (51%)
Frame = +3
Query: 306 SATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDAD 485
S + +D KLY ++ +R ++ + +Y +IRGFCHL GQE V + R+ D
Sbjct: 21 SCKIRYDDVEKLYRKMLCMRYMDESISKMYSRGLIRGFCHLDIGQEEVYAALCHVARN-D 79
Query: 486 SVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
I +YRCH + V ++ EL GR G
Sbjct: 80 KFIGSYRCHALAVAAEIPVREIVGELLGRAGG 111
>UniRef50_A3CMZ3 Cluster: Pyruvate dehydrogenase, TPP-dependent E1
component alpha-subunit, putative; n=22; Bacteria|Rep:
Pyruvate dehydrogenase, TPP-dependent E1 component
alpha-subunit, putative - Streptococcus sanguinis
(strain SK36)
Length = 357
Score = 60.9 bits (141), Expect = 2e-08
Identities = 28/89 (31%), Positives = 50/89 (56%)
Frame = +3
Query: 315 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 494
++ E A +Y+ + +R E + + I GF HLY+G+EA+A G+ A + D D +
Sbjct: 39 VSKEKAKTMYKTMWDIRNFEENTRRFFAAGQIPGFVHLYAGEEAIATGVCANLTDKDYIT 98
Query: 495 TAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
+ +R HG G + G+++E+ G+ TG
Sbjct: 99 STHRGHGHCVAKGGDLKGMMAEIFGKETG 127
>UniRef50_A4VXG8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, eukaryotic type,
alpha subunit; n=40; Streptococcus|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component, eukaryotic type, alpha
subunit - Streptococcus suis (strain 05ZYH33)
Length = 337
Score = 59.7 bits (138), Expect = 5e-08
Identities = 26/90 (28%), Positives = 49/90 (54%)
Frame = +3
Query: 312 TLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSV 491
++T E L ++ ++ +R ++ L + ++G H G+EA AVG A + D D +
Sbjct: 18 SITKEQHLDMFLKMQQIRDVDMKLNKLVRRGFVQGMTHFSVGEEAAAVGPIAGLTDEDII 77
Query: 492 ITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
+ +R HG G+ + G+++EL G+ TG
Sbjct: 78 FSHHRGHGHVIAKGIDINGMMAELAGKATG 107
>UniRef50_Q13GQ3 Cluster: Putative 2-oxo acid dehydrogenase alpha
subunit; n=1; Burkholderia xenovorans LB400|Rep:
Putative 2-oxo acid dehydrogenase alpha subunit -
Burkholderia xenovorans (strain LB400)
Length = 334
Score = 59.3 bits (137), Expect = 7e-08
Identities = 26/83 (31%), Positives = 45/83 (54%)
Frame = +3
Query: 333 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 512
+ +Y + ++R +E + L+ + + GF HL GQEAV+ G+ + + D++ T +R H
Sbjct: 20 IDIYRTMVLVREVELSLSRLFADSEVPGFIHLSLGQEAVSAGVASVLEVQDTLATTHRGH 79
Query: 513 GWTYLMGVSVLGVLSELTGRRTG 581
G G+ V G E+ GR G
Sbjct: 80 GHVLARGIDVGGFFKEIMGRVGG 102
>UniRef50_Q97YF6 Cluster: Pyruvate dehydrogenase, alpha subunit
(Lipoamide); n=2; Sulfolobaceae|Rep: Pyruvate
dehydrogenase, alpha subunit (Lipoamide) - Sulfolobus
solfataricus
Length = 345
Score = 59.3 bits (137), Expect = 7e-08
Identities = 36/101 (35%), Positives = 54/101 (53%), Gaps = 9/101 (8%)
Frame = +3
Query: 306 SATLTSEDALKLYEQLTILRRIETASGNLYKEKI---------IRGFCHLYSGQEAVAVG 458
+A L + D L +Y+++ I+R E + +Y E IRG HL GQEAVAVG
Sbjct: 18 NAGLKASDLLNMYKRMLIIRYFEESIRKIYHEGKNPFNMASGRIRGEMHLSIGQEAVAVG 77
Query: 459 MRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
+RD D V++ +R H GV + G+ +E+ G+ TG
Sbjct: 78 TLYDIRDEDVVVSTHRPHHHAIAKGVDLKGLAAEILGKATG 118
>UniRef50_Q3J9C5 Cluster: Dehydrogenase, E1 component; n=3;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 339
Score = 58.8 bits (136), Expect = 9e-08
Identities = 37/90 (41%), Positives = 45/90 (50%), Gaps = 5/90 (5%)
Frame = +3
Query: 327 DALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG---MRAAMRDA--DSV 491
D +L ++ RR E S Y E+ + GF HLYSGQEAVA G M A R D
Sbjct: 5 DRKRLLREMVFFRRFEDRSFEAYMERKVGGFLHLYSGQEAVATGVLEMVQADRGVGFDYA 64
Query: 492 ITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
IT YR H G V++EL G+ TG
Sbjct: 65 ITGYRDHIHAIKAGAPAREVMAELYGKETG 94
>UniRef50_Q83X26 Cluster: Probable pyruvate dehydrogenase
alpha-subunit; n=1; Streptomyces rochei|Rep: Probable
pyruvate dehydrogenase alpha-subunit - Streptomyces
rochei (Streptomyces parvullus)
Length = 326
Score = 58.8 bits (136), Expect = 9e-08
Identities = 33/84 (39%), Positives = 49/84 (58%), Gaps = 1/84 (1%)
Frame = +3
Query: 336 KLYEQLTILRRIETASGNLYK-EKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 512
+L + +R IE ++Y+ E+ +R HL GQEAVAVG+ AA+R D V + +RCH
Sbjct: 5 QLLRTMVRIRCIEEEIADVYRDEQQMRTPVHLSIGQEAVAVGVCAALRTEDVVYSGHRCH 64
Query: 513 GWTYLMGVSVLGVLSELTGRRTGC 584
G + +++EL GR TGC
Sbjct: 65 AHYLAKGGGLGAMVAELYGRETGC 88
>UniRef50_Q6MAE2 Cluster: Putative pyruvate dehydrogenase
(Lipoamide), E1 component, alpha chain; n=1; Candidatus
Protochlamydia amoebophila UWE25|Rep: Putative pyruvate
dehydrogenase (Lipoamide), E1 component, alpha chain -
Protochlamydia amoebophila (strain UWE25)
Length = 342
Score = 58.4 bits (135), Expect = 1e-07
Identities = 27/83 (32%), Positives = 47/83 (56%)
Frame = +3
Query: 333 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 512
++ ++Q+ +R E + + Y++ I GF H Y GQEA+ A+ ++ T+YRCH
Sbjct: 27 IECFQQMLKIRNFELRAESAYQQGKIGGFFHAYVGQEAIQTAAVQAIGQSNWYATSYRCH 86
Query: 513 GWTYLMGVSVLGVLSELTGRRTG 581
L+G + +++EL GR TG
Sbjct: 87 ALALLLGATPNELMAELYGRATG 109
>UniRef50_A4AFX0 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=1; marine actinobacterium PHSC20C1|Rep:
Acetoin dehydrogenase (TPP-dependent) alpha chain -
marine actinobacterium PHSC20C1
Length = 327
Score = 58.4 bits (135), Expect = 1e-07
Identities = 30/85 (35%), Positives = 44/85 (51%)
Frame = +3
Query: 327 DALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYR 506
DAL+L + +R E L+ + ++RG HL GQEAV VG+ +A+ D++ YR
Sbjct: 17 DALELLRSMYEIRFFEDEIMGLFSQNLVRGSTHLCQGQEAVTVGVCSALSPGDTMTCTYR 76
Query: 507 CHGWTYLMGVSVLGVLSELTGRRTG 581
HG MG + E+ GR G
Sbjct: 77 GHGAVLAMGAPLDRAFGEILGRAGG 101
>UniRef50_A4X7T3 Cluster: Dehydrogenase, E1 component; n=3;
Actinomycetales|Rep: Dehydrogenase, E1 component -
Salinispora tropica CNB-440
Length = 323
Score = 58.0 bits (134), Expect = 2e-07
Identities = 31/89 (34%), Positives = 47/89 (52%)
Frame = +3
Query: 315 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 494
+T +++LY + ++RR E + L + I G H Y GQE +A G+ AA+R D V
Sbjct: 1 MTEVGSVRLYRTVRLIRRFEERAIELVRSGHIVGGIHPYVGQEGIAAGVCAALRPDDVVA 60
Query: 495 TAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
+R HG G +++EL GR TG
Sbjct: 61 GTHRGHGHVLAKGADPARMMAELCGRVTG 89
>UniRef50_Q3DZ88 Cluster: Dehydrogenase, E1 component; n=1;
Chloroflexus aurantiacus J-10-fl|Rep: Dehydrogenase, E1
component - Chloroflexus aurantiacus J-10-fl
Length = 334
Score = 56.0 bits (129), Expect = 6e-07
Identities = 27/78 (34%), Positives = 43/78 (55%)
Frame = +3
Query: 348 QLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYL 527
++ I+R E + L+ ++ G HL GQEAVA+G AAM+ D ++ +R HG
Sbjct: 33 RMQIIRAFEEKAEELFARGLVHGTMHLSIGQEAVAIGASAAMKPGDYLLNHHRGHGHCLA 92
Query: 528 MGVSVLGVLSELTGRRTG 581
G V +++E G+ TG
Sbjct: 93 WGSDVRLMMAEFLGKETG 110
>UniRef50_Q0LRY7 Cluster: Dehydrogenase, E1 component:Transketolase,
central region:Transketolase-like; n=3; cellular
organisms|Rep: Dehydrogenase, E1
component:Transketolase, central
region:Transketolase-like - Caulobacter sp. K31
Length = 680
Score = 54.4 bits (125), Expect = 2e-06
Identities = 34/103 (33%), Positives = 49/103 (47%), Gaps = 8/103 (7%)
Frame = +3
Query: 297 PATSATLTSEDALK------LYEQLTILRRIETASGNLYKEKIIR--GFCHLYSGQEAVA 452
P T+ T EDA K ++ ++ +R E + L + R G HL +GQE V
Sbjct: 2 PGTNPRATKEDAAKAAFLSEMFGKICFVRAFEEEALRLTQANPPRVAGSMHLCAGQEVVP 61
Query: 453 VGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
V A+ D D V+ YR HGW G+ V++E+ R TG
Sbjct: 62 VAAMEALGDEDQVVCTYRGHGWALAAGLDPEAVMAEICQRSTG 104
>UniRef50_A5V557 Cluster: Pyruvate dehydrogenase; n=1; Sphingomonas
wittichii RW1|Rep: Pyruvate dehydrogenase - Sphingomonas
wittichii RW1
Length = 331
Score = 54.4 bits (125), Expect = 2e-06
Identities = 26/87 (29%), Positives = 48/87 (55%)
Frame = +3
Query: 321 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 500
++ +L+ Y ++ +R+ E + ++ + I G H Y+GQEA VG A+ D D ++
Sbjct: 6 NDRSLEKYRRMQRIRQFEDLAEAIHAQGEIPGSLHTYAGQEASGVGACMALDDTDYMVGT 65
Query: 501 YRCHGWTYLMGVSVLGVLSELTGRRTG 581
+R HG G + +++EL G+ TG
Sbjct: 66 HRSHGHPIAKGAKLRPLMAELLGKATG 92
>UniRef50_P27745 Cluster: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase subunit alpha; n=58; cellular
organisms|Rep: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase subunit alpha - Ralstonia eutropha
(strain ATCC 17699 / H16 / DSM 428 / Stanier
337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM
428 / Stanier337))
Length = 333
Score = 54.4 bits (125), Expect = 2e-06
Identities = 27/89 (30%), Positives = 45/89 (50%)
Frame = +3
Query: 315 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 494
L E L +Y ++ +R E + I GF HLY+G+EA VG+ + D D +
Sbjct: 14 LDKETLLTVYRKMRTIRDFEERLHVDFGRGDIPGFVHLYAGEEAAGVGILHHLNDGDRIA 73
Query: 495 TAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
+ +R HG GV + ++ E+ G++ G
Sbjct: 74 STHRGHGHCIAKGVDPVAMMKEIYGKKGG 102
>UniRef50_Q7V0M7 Cluster: Dehydrogenase, E1 component; n=1;
Prochlorococcus marinus subsp. pastoris str.
CCMP1986|Rep: Dehydrogenase, E1 component -
Prochlorococcus marinus subsp. pastoris (strain CCMP
1378 / MED4)
Length = 324
Score = 54.0 bits (124), Expect = 2e-06
Identities = 26/75 (34%), Positives = 44/75 (58%)
Frame = +3
Query: 360 LRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVS 539
+R IE A +L K+ +RG H Y G+EA+A G+ + + D+V + +R HG G +
Sbjct: 41 IRAIEEAIVSLAKDNKLRGPIHSYVGEEAIATGVLSHAKPIDAVTSTHRGHGHYIAKGGN 100
Query: 540 VLGVLSELTGRRTGC 584
+ ++ EL G+ +GC
Sbjct: 101 ISMLIDELHGKESGC 115
>UniRef50_Q2ITF8 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=1; Rhodopseudomonas palustris HaA2|Rep:
Acetoin dehydrogenase (TPP-dependent) alpha chain -
Rhodopseudomonas palustris (strain HaA2)
Length = 323
Score = 53.2 bits (122), Expect = 4e-06
Identities = 30/88 (34%), Positives = 45/88 (51%)
Frame = +3
Query: 321 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 500
SE +L + +R +E Y E+ +R HL GQEAVA AA+ AD ++
Sbjct: 2 SELPRRLLFDMMRIRAVEETIAKRYGEQKMRCPTHLSVGQEAVAAAAGAALEPADLAVSG 61
Query: 501 YRCHGWTYLMGVSVLGVLSELTGRRTGC 584
+R H G S+ +++E+ GR TGC
Sbjct: 62 HRAHAHYLAKGGSLKAMIAEIYGRVTGC 89
>UniRef50_Q2BFQ9 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. NRRL B-14911|Rep: Putative uncharacterized
protein - Bacillus sp. NRRL B-14911
Length = 668
Score = 52.4 bits (120), Expect = 8e-06
Identities = 28/89 (31%), Positives = 48/89 (53%)
Frame = +3
Query: 315 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 494
L+ E +Y+++ +R +E +L+ + + G H GQEA AV A +++ D V
Sbjct: 14 LSQETIDSMYKKMITIRTLEETLLDLFSKGELFGTTHTSIGQEANAVASMAHIKNGDVVF 73
Query: 495 TAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
+ +RCHG G V +++E+ GR TG
Sbjct: 74 SNHRCHGHYIAYGAPVDQLIAEVMGRVTG 102
>UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component beta;
n=3; Ostreococcus|Rep: Pyruvate dehydrogenase E1
component beta - Ostreococcus tauri
Length = 835
Score = 50.8 bits (116), Expect = 2e-05
Identities = 30/89 (33%), Positives = 42/89 (47%)
Frame = +3
Query: 315 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 494
L+ ED K Y + + R E Y IRGF HL +GQE++ + A+R D
Sbjct: 132 LSDEDLSKAYYMMQLCRDFENECNQAYMAGKIRGFMHLDNGQESIPALLNDAIRKDDLKH 191
Query: 495 TAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
+ YR H GV V++EL G+ G
Sbjct: 192 SYYRDHCHAIACGVDSGAVMAELFGKDGG 220
>UniRef50_Q98FT3 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=6; Bacteria|Rep: Acetoin dehydrogenase
(TPP-dependent) alpha chain - Rhizobium loti
(Mesorhizobium loti)
Length = 342
Score = 50.4 bits (115), Expect = 3e-05
Identities = 25/88 (28%), Positives = 45/88 (51%)
Frame = +3
Query: 318 TSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVIT 497
++E ++ ++ ++RR E + Y +I G HL GQEA A+G+ + + D + +
Sbjct: 23 SAEQLREVLYKMYLIRRFEEGAEESYMRGLIHGTMHLSIGQEASAMGICMPLGEDDQITS 82
Query: 498 AYRCHGWTYLMGVSVLGVLSELTGRRTG 581
+R HG G V + +E G+ TG
Sbjct: 83 THRGHGHCIAKGAEVKRMFAEFFGKTTG 110
>UniRef50_Q479Q2 Cluster: Dehydrogenase, E1 component; n=2;
Rhodocyclaceae|Rep: Dehydrogenase, E1 component -
Dechloromonas aromatica (strain RCB)
Length = 320
Score = 50.4 bits (115), Expect = 3e-05
Identities = 33/88 (37%), Positives = 45/88 (51%)
Frame = +3
Query: 318 TSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVIT 497
T+ D L+LYEQL ++R E A + I G C GQEA AVG A+ D ++T
Sbjct: 6 TAVDPLRLYEQLLLIRAYENAIVRGSTDGRIPGTCTSV-GQEAAAVGAINALEADDLILT 64
Query: 498 AYRCHGWTYLMGVSVLGVLSELTGRRTG 581
+R G G +L+E+ GRR G
Sbjct: 65 NHRSAGHLLARGADPGRMLAEVMGRRDG 92
>UniRef50_A0LFE6 Cluster: Pyruvate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Pyruvate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 320
Score = 50.4 bits (115), Expect = 3e-05
Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Frame = +3
Query: 318 TSEDALKLYEQLTILRRIETASGNLYK-EKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 494
T E L++ + + RR E L + E + G L +GQEAVA G+ AA+ D ++
Sbjct: 4 TKEKLLEMLRSMLLTRRFEEKLTELCQIEGKVPGMMILCTGQEAVAAGVCAALEPQDVIV 63
Query: 495 TAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
+R HG G +++E G+RTG
Sbjct: 64 PNHRSHGHLLARGADPNALMAECFGKRTG 92
>UniRef50_Q18CB6 Cluster: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase alpha subunit; n=2; Clostridium
difficile|Rep: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase alpha subunit - Clostridium difficile
(strain 630)
Length = 322
Score = 49.2 bits (112), Expect = 7e-05
Identities = 25/90 (27%), Positives = 46/90 (51%)
Frame = +3
Query: 312 TLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSV 491
+++ E L++Y+++ R+ E + ++ G HL GQEA +V A+ D V
Sbjct: 4 SISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQEASSVAAVMALEKGDLV 63
Query: 492 ITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
+R H MG+ + +++EL G+ TG
Sbjct: 64 SLTHRGHSQFIGMGIDLNKMMAELMGKETG 93
>UniRef50_Q1NYL5 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=1; Candidatus Sulcia muelleri str. Hc
(Homalodisca coagulata)|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Candidatus Sulcia muelleri
str. Hc (Homalodisca coagulata)
Length = 58
Score = 48.8 bits (111), Expect = 9e-05
Identities = 22/54 (40%), Positives = 35/54 (64%)
Frame = +3
Query: 312 TLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAM 473
T+ ++ LK Y+ ++ R+ E +LY ++ IRGF HLY+GQEA+ G+ AM
Sbjct: 3 TINNDIYLKWYKDMSFWRKFEDKCRSLYLKQKIRGFLHLYNGQEAIPAGLVHAM 56
>UniRef50_A0JUQ5 Cluster: Pyruvate dehydrogenase; n=4;
Actinobacteria (class)|Rep: Pyruvate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 392
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/85 (31%), Positives = 45/85 (52%)
Frame = +3
Query: 315 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 494
++ E LYE + ++RRI+T + L ++ + G GQEA +G ++RD D V
Sbjct: 53 VSDEQLGSLYEDMVVIRRIDTEATALQRQGEL-GLWPPLLGQEASQIGSARSLRDDDFVF 111
Query: 495 TAYRCHGWTYLMGVSVLGVLSELTG 569
++YR +G Y GV + +L G
Sbjct: 112 SSYRENGVAYCRGVDLADILKVWRG 136
>UniRef50_A0UXT3 Cluster: Pyruvate dehydrogenase; n=1; Clostridium
cellulolyticum H10|Rep: Pyruvate dehydrogenase -
Clostridium cellulolyticum H10
Length = 321
Score = 47.6 bits (108), Expect = 2e-04
Identities = 26/90 (28%), Positives = 45/90 (50%)
Frame = +3
Query: 315 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 494
+ +E ++LY + +R +E YK ++ HL GQEA+A G+ +R D +
Sbjct: 1 MENERFIELYRVMQTIRIVERKIEEEYKNDEMKTPIHLSIGQEAIAAGVCINLRKDDYLF 60
Query: 495 TAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
+R H G + +++EL R+TGC
Sbjct: 61 GTHRSHAQYIAKGGDIKQMIAELYLRKTGC 90
>UniRef50_Q2WB98 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex; n=1; Magnetospirillum magneticum AMB-1|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 647
Score = 46.8 bits (106), Expect = 4e-04
Identities = 24/76 (31%), Positives = 41/76 (53%)
Frame = +3
Query: 354 TILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMG 533
T++R +E +LY E + G H GQE V + +A+R D +++ +R HG
Sbjct: 17 TLIRVVEERLLSLYGEGRLHGTVHTCIGQEWTGVSVASALRSGDYILSNHRGHGHYLAWT 76
Query: 534 VSVLGVLSELTGRRTG 581
V G+++E+ GR +G
Sbjct: 77 DDVEGLIAEVMGRESG 92
>UniRef50_Q0MX87 Cluster: Acetoin dehydrogenase alpha-subunit; n=2;
Bacteria|Rep: Acetoin dehydrogenase alpha-subunit -
consortium cosmid clone pGZ1
Length = 344
Score = 46.8 bits (106), Expect = 4e-04
Identities = 23/58 (39%), Positives = 35/58 (60%)
Frame = +3
Query: 408 IRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
+RG HL +GQEAVA G+ + +R D + + +R HG T G + ++ EL GR +G
Sbjct: 52 VRGPLHLSTGQEAVATGVCSQLRADDWLTSTHRGHGHTIAKGADLRRMMHELFGRASG 109
>UniRef50_Q53610 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit; n=16;
Actinomycetales|Rep: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit - Streptomyces
avermitilis
Length = 406
Score = 46.4 bits (105), Expect = 5e-04
Identities = 28/91 (30%), Positives = 41/91 (45%)
Frame = +3
Query: 309 ATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADS 488
A +T E+ LY + + RR + + +L ++ + G GQEA +G A RD D
Sbjct: 63 ADITPEELRGLYRDMVLSRRFDAEATSLQRQGEL-GLWASMLGQEAAQIGSGRATRDDDY 121
Query: 489 VITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
V YR HG + GV +L G G
Sbjct: 122 VFPTYREHGVAWCRGVDPTNLLGMFRGVNNG 152
>UniRef50_Q6A611 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Propionibacterium acnes|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit -
Propionibacterium acnes
Length = 381
Score = 46.0 bits (104), Expect = 7e-04
Identities = 28/96 (29%), Positives = 43/96 (44%)
Frame = +3
Query: 282 KLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 461
+L P L +D +K E + + RR++ + L + + G GQEA G
Sbjct: 40 RLTTHPDFPVDLVDDDLVKALEMMVMTRRLDVEATALQRHGEL-GLWPPLLGQEATQAGA 98
Query: 462 RAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTG 569
A+R+ D V YR G + MGVS+ +L G
Sbjct: 99 WLALREGDQVFPTYREQGLAHAMGVSLADILGAWDG 134
>UniRef50_A6UDY5 Cluster: Dehydrogenase E1 component; n=2;
Alphaproteobacteria|Rep: Dehydrogenase E1 component -
Sinorhizobium medicae WSM419
Length = 342
Score = 46.0 bits (104), Expect = 7e-04
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Frame = +3
Query: 333 LKLYEQLTILRRIETASGNLYKEKIIRG-FCHLYSGQEAVAVGMRAAMRDADSVITAYRC 509
L+LY + +R E G L+ G HL G+E+ A G+ AAM+ D+ T +R
Sbjct: 10 LELYRTMRRIRTFEERVGELFVRGQSAGSMLHLSIGEESSAAGVCAAMKPQDTFTTHHRG 69
Query: 510 HGWTYLMGVSVLGVLSELTGRRTG 581
HG G +++E+ G+ TG
Sbjct: 70 HGIFLARGADPKRMMAEIGGKETG 93
>UniRef50_A6Q3I6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, E1 component, alpha subunit; n=2; unclassified
Epsilonproteobacteria|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, E1 component, alpha subunit -
Nitratiruptor sp. (strain SB155-2)
Length = 323
Score = 45.6 bits (103), Expect = 9e-04
Identities = 30/80 (37%), Positives = 39/80 (48%)
Frame = +3
Query: 342 YEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWT 521
Y + + R E A+ Y + I GF HL GQEA +VG A D V T YR H
Sbjct: 10 YYLMKLGREFEIAAKQEYMKGNIAGFLHLDIGQEACSVGSMQAF-DKGDVFTHYREHVLA 68
Query: 522 YLMGVSVLGVLSELTGRRTG 581
G+ V++EL G+ TG
Sbjct: 69 IARGMDPKVVMAELFGKVTG 88
>UniRef50_Q748I3 Cluster: Dehydrogenase, E1 component, alpha and
beta subunits; n=1; Geobacter sulfurreducens|Rep:
Dehydrogenase, E1 component, alpha and beta subunits -
Geobacter sulfurreducens
Length = 652
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/86 (26%), Positives = 43/86 (50%)
Frame = +3
Query: 324 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 503
+D +L +R++E L+ E ++ G H GQE V + A++ D+V + +
Sbjct: 11 KDCYELTVTALTIRKVEERLLELFSEGVLNGTIHTCIGQEWTGVAVANALQAGDTVFSNH 70
Query: 504 RCHGWTYLMGVSVLGVLSELTGRRTG 581
R HG + V G+++E+ G+ G
Sbjct: 71 RGHGHYIALTGDVYGLIAEIMGKDDG 96
>UniRef50_A6CP23 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=2; Bacillus sp. SG-1|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit - Bacillus
sp. SG-1
Length = 364
Score = 45.2 bits (102), Expect = 0.001
Identities = 26/90 (28%), Positives = 45/90 (50%)
Frame = +3
Query: 315 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 494
+T + A + Y + +R + + +L ++ I + + GQEA VG AA+++ D +
Sbjct: 35 ITEQLAKEFYRHMVRIRTFDKKAISLQRQGRIGTYAP-FEGQEASQVGSSAALKEDDWMF 93
Query: 495 TAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
+YR HG G S+ +L GR GC
Sbjct: 94 PSYRDHGAAMTFGHSLRNILLFWKGRNEGC 123
>UniRef50_A7HBV0 Cluster: 3-methyl-2-oxobutanoate dehydrogenase;
n=4; Cystobacterineae|Rep: 3-methyl-2-oxobutanoate
dehydrogenase - Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 44.8 bits (101), Expect = 0.002
Identities = 27/92 (29%), Positives = 45/92 (48%)
Frame = +3
Query: 294 GPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAM 473
G TL + L+LY + + R ++ L ++ I GF G+EA +G AAM
Sbjct: 44 GAPDEVTLPDAEVLRLYRLMVLNRSLDERMITLQRQGRI-GFYIGSIGEEATILGSAAAM 102
Query: 474 RDADSVITAYRCHGWTYLMGVSVLGVLSELTG 569
++D + YR HG + G+ ++ L +L G
Sbjct: 103 AESDWIFPCYREHGAALMRGMPLVTFLCDLFG 134
>UniRef50_A6WG12 Cluster: Pyruvate dehydrogenase; n=3;
Actinomycetales|Rep: Pyruvate dehydrogenase -
Kineococcus radiotolerans SRS30216
Length = 390
Score = 44.4 bits (100), Expect = 0.002
Identities = 29/91 (31%), Positives = 40/91 (43%)
Frame = +3
Query: 297 PATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 476
P L E+ L L + +LRR++ A G + + G GQEA VG A R
Sbjct: 36 PEHEVDLEPEELLALLRDMVLLRRLD-AEGEALQRQGQLGLWPGSRGQEAAQVGSATACR 94
Query: 477 DADSVITAYRCHGWTYLMGVSVLGVLSELTG 569
D V +YR HG G+ + +LS G
Sbjct: 95 RQDQVFPSYRDHGAVLGRGIDPVDILSIFRG 125
>UniRef50_A5U0N1 Cluster: Dehydrogenase E1 component; n=7;
Mycobacterium tuberculosis complex|Rep: Dehydrogenase E1
component - Mycobacterium tuberculosis (strain ATCC
25177 / H37Ra)
Length = 334
Score = 44.4 bits (100), Expect = 0.002
Identities = 26/82 (31%), Positives = 43/82 (52%)
Frame = +3
Query: 336 KLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHG 515
+LY ++ +LR ++ A L E +I G GQEAV+VG AA+ + D +IT +R H
Sbjct: 18 ELYRRMWVLRLLDMALEQLRIEGLINGPLQGGFGQEAVSVGAAAALGEGDVIITTHRPHA 77
Query: 516 WTYLMGVSVLGVLSELTGRRTG 581
+ V++++ G G
Sbjct: 78 QHVGTDAPLGPVIADMLGATAG 99
>UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=3; Brucella|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 725
Score = 44.0 bits (99), Expect = 0.003
Identities = 21/62 (33%), Positives = 32/62 (51%)
Frame = +3
Query: 327 DALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYR 506
D LK Y Q+ ++RR E + K ++ G H GQEA AVG + ++ D + +R
Sbjct: 30 DLLKWYSQMKLIRRFEEKILDFEKAGLVHGPAHASIGQEAAAVGAMSVLKTDDQINGTHR 89
Query: 507 CH 512
H
Sbjct: 90 TH 91
>UniRef50_Q67SE7 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Bacilli|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Symbiobacterium thermophilum
Length = 368
Score = 44.0 bits (99), Expect = 0.003
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 2/89 (2%)
Frame = +3
Query: 321 SEDALK-LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR-DADSVI 494
S D LK +Y ++ LR + NL ++ + F +SGQEA VG +R D D +
Sbjct: 35 SVDQLKDVYRKMVYLRVFDQRCLNLQRQGRMGTFAP-FSGQEASQVGSAYLLRPDRDWIF 93
Query: 495 TAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
YR HG ++MGV ++ +L G G
Sbjct: 94 PTYRDHGAMHVMGVPLVNILRYFMGDEQG 122
>UniRef50_Q319T4 Cluster: Pyruvate dehydrogenase; n=1;
Prochlorococcus marinus str. MIT 9312|Rep: Pyruvate
dehydrogenase - Prochlorococcus marinus (strain MIT
9312)
Length = 347
Score = 43.6 bits (98), Expect = 0.004
Identities = 21/86 (24%), Positives = 43/86 (50%)
Frame = +3
Query: 324 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 503
++ L++ ++ ++R E + ++ G HL GQEA+ VG+ + + D V A+
Sbjct: 26 DELLEMLSKMILIRNAEYKIAKGREFGLVGGPVHLGVGQEAIPVGISQYLNNQDKVFGAH 85
Query: 504 RCHGWTYLMGVSVLGVLSELTGRRTG 581
R H +G+ + SE+ + +G
Sbjct: 86 RSHSHILSLGIDLKSFFSEILAKSSG 111
>UniRef50_Q0ET31 Cluster: Dehydrogenase, E1 component; n=1;
Thermoanaerobacter ethanolicus X514|Rep: Dehydrogenase,
E1 component - Thermoanaerobacter ethanolicus X514
Length = 262
Score = 42.3 bits (95), Expect = 0.008
Identities = 26/99 (26%), Positives = 48/99 (48%), Gaps = 10/99 (10%)
Frame = +3
Query: 315 LTSEDALKLYEQLTILRRIETASGNLYKEKI----------IRGFCHLYSGQEAVAVGMR 464
+ E +++Y ++ +R E Y+E + G HL +GQE VAVG+
Sbjct: 3 IPKETLIRMYLEMVTIRLYEETMAEAYQEGKYPVFNIASGPVPGEMHLAAGQEPVAVGVC 62
Query: 465 AAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
++ D+V+ +R H + GV + + +E+ G+ TG
Sbjct: 63 MHLKKEDAVVGTHRPHHFAIAKGVDLKRMTAEIFGKVTG 101
>UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3;
Bacteria|Rep: Transketolase, central region -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 823
Score = 42.3 bits (95), Expect = 0.008
Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 7/88 (7%)
Frame = +3
Query: 318 TSEDALKLYEQLTILRRIETASGNLYKEKIIRGF-------CHLYSGQEAVAVGMRAAMR 476
+ ED L++Y + I+R ET + G HL GQEA AVG +
Sbjct: 40 SDEDLLRIYRDMLIIREFETMLSLIKTRGEYNGIKYDYPGPAHLSIGQEAAAVGQAFILD 99
Query: 477 DADSVITAYRCHGWTYLMGVSVLGVLSE 560
D + ++R HG G+S + LSE
Sbjct: 100 KNDFIFGSHRSHGEVIAKGLSAIEKLSE 127
>UniRef50_A4XF89 Cluster: Dehydrogenase, E1 component; n=1;
Novosphingobium aromaticivorans DSM 12444|Rep:
Dehydrogenase, E1 component - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 315
Score = 42.3 bits (95), Expect = 0.008
Identities = 24/81 (29%), Positives = 38/81 (46%)
Frame = +3
Query: 339 LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGW 518
++ +L + R +ET +E+ G+ H GQEA +G AA+ D V R W
Sbjct: 12 MFHKLAVSRAVETLMLRHTREERFSGWWHPGEGQEAAPIGATAALEADDYVWYQGRGCAW 71
Query: 519 TYLMGVSVLGVLSELTGRRTG 581
G+ L +L +L G+ G
Sbjct: 72 AIGKGMDPLPILGDLLGKTNG 92
>UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta
subunit; n=1; Roseovarius nubinhibens ISM|Rep:
2-oxoisovalerate dehydrogenase beta subunit -
Roseovarius nubinhibens ISM
Length = 746
Score = 42.3 bits (95), Expect = 0.008
Identities = 20/59 (33%), Positives = 31/59 (52%)
Frame = +3
Query: 336 KLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 512
++ EQL ++R E L KE ++ G H GQE AVG+ +A+ D + +R H
Sbjct: 47 RMLEQLFLIRHFEERLLELSKEGLLHGPAHASIGQEGAAVGLMSALTSGDKINGTHRMH 105
>UniRef50_Q9HN77 Cluster: Pyruvate dehydrogenase alpha subunit; n=8;
Halobacteriaceae|Rep: Pyruvate dehydrogenase alpha
subunit - Halobacterium salinarium (Halobacterium
halobium)
Length = 419
Score = 41.1 bits (92), Expect = 0.019
Identities = 23/89 (25%), Positives = 45/89 (50%)
Frame = +3
Query: 315 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 494
LT ++ +++Y + + RR + + +L ++ I + L SGQE + A+ D D ++
Sbjct: 79 LTDDELVEMYRYMKLARRFDERAVSLQRQGRIGTYPPL-SGQEGAQIASAMALADDDWIV 137
Query: 495 TAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
+YR HG + + G+ + L G G
Sbjct: 138 PSYREHGASLVRGLPLKDTLLYWMGDERG 166
>UniRef50_Q7N3C2 Cluster: Similar to 3-methyl-2-oxobutanoate
dehydrogenase; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to 3-methyl-2-oxobutanoate
dehydrogenase - Photorhabdus luminescens subsp.
laumondii
Length = 650
Score = 40.3 bits (90), Expect = 0.033
Identities = 22/75 (29%), Positives = 35/75 (46%)
Frame = +3
Query: 357 ILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGV 536
++R E A LY + G H GQE + ++ D V + +RCHG
Sbjct: 11 LIRETEEALLRLYSTGELHGTVHTCIGQELTGAIVCKFLKKNDWVFSNHRCHGHFLSRTG 70
Query: 537 SVLGVLSELTGRRTG 581
V G+++E+ G+ TG
Sbjct: 71 DVTGLIAEVMGKETG 85
>UniRef50_Q11G20 Cluster: Twin-arginine translocation pathway
signal; n=2; Proteobacteria|Rep: Twin-arginine
translocation pathway signal - Mesorhizobium sp. (strain
BNC1)
Length = 375
Score = 40.3 bits (90), Expect = 0.033
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 10/92 (10%)
Frame = +3
Query: 336 KLYEQLTILRRIE----TASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI--- 494
+L + T + RI T + + + RG+ H Y+GQEAVAVG+ +A+R++ V+
Sbjct: 30 QLVDMFTTILRIRWHERTMADKMLTDPNYRGYNHFYAGQEAVAVGVCSALRNSGGVMHAD 89
Query: 495 TAYRCH---GWTYLMGVSVLGVLSELTGRRTG 581
AY H G GV + + +E R TG
Sbjct: 90 LAYSTHRPTGHAIAKGVDMKLMAAENDFRATG 121
>UniRef50_Q8U4T5 Cluster: 2-oxo acid dehydrogenase subunit E1; n=1;
Haloferax volcanii|Rep: 2-oxo acid dehydrogenase subunit
E1 - Halobacterium volcanii (Haloferax volcanii)
Length = 353
Score = 40.3 bits (90), Expect = 0.033
Identities = 21/58 (36%), Positives = 31/58 (53%)
Frame = +3
Query: 408 IRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
I G HL +G EA G+ +RD D+V +R H GV + + +E+ GR+TG
Sbjct: 43 IPGELHLAAGHEASGAGVCMHLRDDDTVTAPHRPHHIAIAKGVDLKRMTAEIFGRKTG 100
>UniRef50_A3RZM3 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=5; Proteobacteria|Rep: Pyruvate dehydrogenase
E1 component alpha subunit - Ralstonia solanacearum
UW551
Length = 368
Score = 39.9 bits (89), Expect = 0.043
Identities = 24/70 (34%), Positives = 36/70 (51%)
Frame = +3
Query: 333 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 512
L LY + + R +T + L + + F GQEA+ VG+ +AMR D + +YR H
Sbjct: 36 LALYRAMVLTRAFDTKAIALQRTGKLGTFASSV-GQEAIGVGVASAMRAEDVLFPSYRDH 94
Query: 513 GWTYLMGVSV 542
L GVS+
Sbjct: 95 SAQLLRGVSM 104
>UniRef50_Q83DQ6 Cluster: Dehydrogenase, E1 component, alpha
subunit; n=3; Coxiella burnetii|Rep: Dehydrogenase, E1
component, alpha subunit - Coxiella burnetii
Length = 368
Score = 38.7 bits (86), Expect = 0.100
Identities = 24/83 (28%), Positives = 42/83 (50%)
Frame = +3
Query: 333 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 512
L LY ++ ++R+++ + NL + + G GQEAV +GM +AM+ D YR
Sbjct: 39 LYLYRRMALIRQLDNKAINLQRTGKM-GTYPSSRGQEAVGIGMGSAMQKEDIFCPYYRDQ 97
Query: 513 GWTYLMGVSVLGVLSELTGRRTG 581
G + G+ + +L+ G G
Sbjct: 98 GALFEHGIKLSEILAYWGGDERG 120
>UniRef50_Q02C52 Cluster: Pyruvate dehydrogenase; n=1; Solibacter
usitatus Ellin6076|Rep: Pyruvate dehydrogenase -
Solibacter usitatus (strain Ellin6076)
Length = 340
Score = 38.7 bits (86), Expect = 0.100
Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Frame = +3
Query: 300 ATSATLTSEDALKLYEQLTILRRIETA-SGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 476
+ + +L +E A K + ++R +E LY++ I G ++ GQEA+ VG
Sbjct: 16 SAAGSLQAELAHKCLYYMLLMREVEDRIERKLYRQGKILGGVYVGRGQEAIPVGSALVAV 75
Query: 477 DADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
D + ++R ++ GVS VL++ GR G
Sbjct: 76 PEDVMFPSHRDMAVFFIRGVSARRVLAQYMGRLGG 110
>UniRef50_Q5SJR9 Cluster: Pyruvate dehydrogenase (Lipoamide) (EC
1.2.4.1) E1-alpha chain; n=2; Thermus thermophilus|Rep:
Pyruvate dehydrogenase (Lipoamide) (EC 1.2.4.1) E1-alpha
chain - Thermus thermophilus (strain HB8 / ATCC 27634 /
DSM 579)
Length = 346
Score = 38.3 bits (85), Expect = 0.13
Identities = 25/82 (30%), Positives = 42/82 (51%)
Frame = +3
Query: 261 IKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQ 440
+KP + LD+G L E+AL+LY + R + + L ++ + G + GQ
Sbjct: 1 MKPKVVRYLDEG---EFPLAEEEALRLYRAMRRARFFDEKALTLQRQGRL-GVYAPFMGQ 56
Query: 441 EAVAVGMRAAMRDADSVITAYR 506
EA VG+ A+ + D V+ +YR
Sbjct: 57 EAAQVGVALALEERDWVVPSYR 78
>UniRef50_Q1LFS5 Cluster: Dehydrogenase, E1 component; n=22;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM
2839)
Length = 367
Score = 38.3 bits (85), Expect = 0.13
Identities = 21/70 (30%), Positives = 37/70 (52%)
Frame = +3
Query: 333 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 512
L LY + + R+ + + + + I F GQEA+ VG+ AMR D ++ +YR H
Sbjct: 36 LPLYRAMVLTRQFDLKAIAMQRTGQIGTFASAL-GQEAIGVGVATAMRRDDVLVPSYRDH 94
Query: 513 GWTYLMGVSV 542
++ GV++
Sbjct: 95 AAQFVRGVTM 104
>UniRef50_UPI00005103B4 Cluster: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit; n=1; Brevibacterium
linens BL2|Rep: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit - Brevibacterium linens
BL2
Length = 368
Score = 37.5 bits (83), Expect = 0.23
Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 1/97 (1%)
Frame = +3
Query: 282 KLDQGPATSATLTSEDALK-LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 458
+L P + S+ AL LY Q+ ++RR E +L ++ + + +GQEA VG
Sbjct: 26 RLTDTPTEGLRIPSDAALTGLYRQMVLVRRFEAQVTHLTRQGRLATYPSA-AGQEAAEVG 84
Query: 459 MRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTG 569
A+ D + YR GV V +L+ G
Sbjct: 85 ATTALAPNDWLFPTYRDSAALLTRGVPVAEILAAFRG 121
>UniRef50_Q93N50 Cluster: Pyruvate dehydrogenase alpha subunit; n=4;
Proteobacteria|Rep: Pyruvate dehydrogenase alpha subunit
- Coxiella burnetii
Length = 341
Score = 37.1 bits (82), Expect = 0.30
Identities = 24/81 (29%), Positives = 42/81 (51%)
Frame = +3
Query: 339 LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGW 518
LY+ L I R IE Y + +R HL GQEA+ + + + + D +++ +R H
Sbjct: 11 LYKLLRI-RMIEEEIVLQYPKGKMRCPTHLSIGQEAIPIMVCENLHNTDLMVSTHRAHAH 69
Query: 519 TYLMGVSVLGVLSELTGRRTG 581
G ++ +++EL G+ TG
Sbjct: 70 YLAKGGNLKALIAELHGKVTG 90
>UniRef50_Q6YPX5 Cluster: Thiamine pyrophosphate-dependent
dehydrogenase, E1 component alpha subunit; n=2;
Candidatus Phytoplasma asteris|Rep: Thiamine
pyrophosphate-dependent dehydrogenase, E1 component
alpha subunit - Onion yellows phytoplasma
Length = 363
Score = 37.1 bits (82), Expect = 0.30
Identities = 27/82 (32%), Positives = 41/82 (50%)
Frame = +3
Query: 297 PATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 476
P L+ + LK+Y+ + + R+ + A+ Y+ + G L SGQEA VG+ AA+
Sbjct: 26 PELEPKLSKDVLLKMYKTMVLGRQADLAALK-YQRQGRMGNYLLNSGQEASQVGVAAALE 84
Query: 477 DADSVITAYRCHGWTYLMGVSV 542
D V YR G GVS+
Sbjct: 85 PQDWVSPYYRDAGIFLYRGVSL 106
>UniRef50_UPI0000384B37 Cluster: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit; n=1; Magnetospirillum
magnetotacticum MS-1|Rep: COG1071:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component, eukaryotic type, alpha
subunit - Magnetospirillum magnetotacticum MS-1
Length = 311
Score = 36.7 bits (81), Expect = 0.40
Identities = 25/81 (30%), Positives = 36/81 (44%)
Frame = +3
Query: 339 LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGW 518
L Q+ +R + K K R HL G EA+AV + AAM + DS+ +R +
Sbjct: 12 LARQVLRVRLAQMLINEALKAKKFRVPVHLALGHEAIAVAVGAAMAEGDSLFLTHRNIHY 71
Query: 519 TYLMGVSVLGVLSELTGRRTG 581
S+ +SEL R G
Sbjct: 72 NIARATSLAAEVSELALRPDG 92
>UniRef50_Q9K3H0 Cluster: Putative pyruvate dehydrogenase alpha
subunit; n=2; Bacteria|Rep: Putative pyruvate
dehydrogenase alpha subunit - Streptomyces coelicolor
Length = 323
Score = 36.7 bits (81), Expect = 0.40
Identities = 21/74 (28%), Positives = 35/74 (47%)
Frame = +3
Query: 351 LTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLM 530
L ++R E A L+ + + G H GQE + V + + + D V + +R HG
Sbjct: 38 LLMIRHFELAVLELFSQGRLHGTTHTCLGQEYIPVALYPLLDEGDYVFSNHRGHGHYLAR 97
Query: 531 GVSVLGVLSELTGR 572
G+L+E+ GR
Sbjct: 98 FHDPHGLLAEIMGR 111
>UniRef50_A0K283 Cluster: Pyruvate dehydrogenase; n=4;
Actinobacteria (class)|Rep: Pyruvate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 415
Score = 36.7 bits (81), Expect = 0.40
Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 3/102 (2%)
Frame = +3
Query: 285 LDQGPATSATLTSEDALKL---YEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAV 455
L + P SA DA KL Y + +RR + + L ++ + + L +GQEA +
Sbjct: 45 LGEDPVFSAYANRLDAEKLRGFYADMAAIRRFDQEATALQRQGQLALWVPL-TGQEAAQI 103
Query: 456 GMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 581
G A + D + YR HG V + +L + G G
Sbjct: 104 GSGRASQPQDYIFPTYREHGVALTRNVDLAELLRQFRGVSNG 145
>UniRef50_Q2J998 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp.
CcI3|Rep: Pyruvate dehydrogenase - Frankia sp. (strain
CcI3)
Length = 417
Score = 36.3 bits (80), Expect = 0.53
Identities = 23/79 (29%), Positives = 39/79 (49%)
Frame = +3
Query: 333 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 512
++ Y + + RR++ + L ++ + + L GQEA VG AA R D + +YR H
Sbjct: 76 MEFYTSMVLARRLDEEATALQRQGELVLWIPL-RGQEAAQVGSAAAARPRDYLFPSYREH 134
Query: 513 GWTYLMGVSVLGVLSELTG 569
+ GV + V+ L G
Sbjct: 135 AVAWHRGVPAVEVIRLLRG 153
>UniRef50_Q3WCG3 Cluster: Pyruvate dehydrogenase; n=4;
Actinomycetales|Rep: Pyruvate dehydrogenase - Frankia
sp. EAN1pec
Length = 332
Score = 36.3 bits (80), Expect = 0.53
Identities = 21/82 (25%), Positives = 38/82 (46%)
Frame = +3
Query: 336 KLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHG 515
+LYE +T+++ + ++ GQEA+A M +R D ++T YR
Sbjct: 16 RLYELMTLMKAADDRLSRGIASGELQCVYWPPRGQEAIAAAMGVCLRSDDQLVTTYRGLH 75
Query: 516 WTYLMGVSVLGVLSELTGRRTG 581
GV ++ + E+ GR+ G
Sbjct: 76 DLIGKGVPLVEIYGEMLGRQVG 97
>UniRef50_UPI00004D6EAE Cluster: Ras and Rab interactor 1 (Ras
interaction/interference protein 1) (Ras inhibitor
JC99).; n=2; Xenopus tropicalis|Rep: Ras and Rab
interactor 1 (Ras interaction/interference protein 1)
(Ras inhibitor JC99). - Xenopus tropicalis
Length = 752
Score = 35.9 bits (79), Expect = 0.70
Identities = 26/95 (27%), Positives = 42/95 (44%)
Frame = +3
Query: 195 KVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIE 374
KV P+ T ++ ++ + P ++ D G ++S TSED K QLT R+I+
Sbjct: 308 KVPVPLTRTQESKEIEQSSSNGLSPVEVQ--DSGSSSSEEGTSEDFGKFSPQLTRRRKIK 365
Query: 375 TASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRD 479
SG + F L S + V + + RD
Sbjct: 366 KKSGRSSFRAVSGAFLSLLSPERKVLMFIEEMSRD 400
>UniRef50_Q8CX87 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=5; Bacillaceae|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit -
Oceanobacillus iheyensis
Length = 358
Score = 35.9 bits (79), Expect = 0.70
Identities = 25/82 (30%), Positives = 38/82 (46%)
Frame = +3
Query: 336 KLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHG 515
+ Y QL +R + + NL ++ I G + GQE VG A+ + D ++ YR H
Sbjct: 37 QFYRQLICMRAFDQKAINLQRQGRI-GTYPGFEGQEGAQVGSALALDEDDWMLPTYRDHA 95
Query: 516 WTYLMGVSVLGVLSELTGRRTG 581
+ G S +LS GR G
Sbjct: 96 ASITFGKSYT-ILSSWNGRVEG 116
>UniRef50_Q83FF2 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=2; Tropheryma whipplei|Rep: Pyruvate
dehydrogenase E1 component alpha subunit - Tropheryma
whipplei (strain Twist) (Whipple's bacillus)
Length = 370
Score = 35.5 bits (78), Expect = 0.93
Identities = 20/86 (23%), Positives = 41/86 (47%)
Frame = +3
Query: 312 TLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSV 491
+L ED + Y + ++R+I+ + L + + + +Y GQEA +G A + D +
Sbjct: 33 SLDVEDIQRFYRDIILVRQIDHEAALLQRRGELALWPPVY-GQEASQIGATYACSENDMI 91
Query: 492 ITAYRCHGWTYLMGVSVLGVLSELTG 569
+YR H + G+ ++ + G
Sbjct: 92 FPSYRDHAVMHARGIDLVHIAKLFRG 117
>UniRef50_A7D3P2 Cluster: Pyruvate dehydrogenase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Pyruvate dehydrogenase -
Halorubrum lacusprofundi ATCC 49239
Length = 382
Score = 35.5 bits (78), Expect = 0.93
Identities = 23/72 (31%), Positives = 34/72 (47%)
Frame = +3
Query: 300 ATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRD 479
AT L+ E +Y L RR + + +L ++ I + +GQE AVG A+ D
Sbjct: 35 ATVPDLSDERFRAIYRDLVTTRRFDERAVSLQRQGRIGTYAPC-AGQEGSAVGSTHALAD 93
Query: 480 ADSVITAYRCHG 515
D + YR HG
Sbjct: 94 RDLISYQYREHG 105
>UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=10; Bacteria|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 729
Score = 34.7 bits (76), Expect = 1.6
Identities = 17/58 (29%), Positives = 29/58 (50%)
Frame = +3
Query: 339 LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 512
+ Q+ ++R E L + ++ G H GQE AVG +MR +D + ++R H
Sbjct: 34 MLSQMHLIRAFEEKVLELAGQGLVHGPAHSAIGQEGGAVGSAVSMRPSDQINGSHRAH 91
>UniRef50_A3DC57 Cluster: Methyl-accepting chemotaxis sensory
transducer; n=1; Clostridium thermocellum ATCC
27405|Rep: Methyl-accepting chemotaxis sensory
transducer - Clostridium thermocellum (strain ATCC 27405
/ DSM 1237)
Length = 600
Score = 34.3 bits (75), Expect = 2.2
Identities = 25/102 (24%), Positives = 40/102 (39%), Gaps = 3/102 (2%)
Frame = +3
Query: 183 NTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTIL 362
NT+ V APV+ E +K +K D +A + D L Y +
Sbjct: 198 NTLDAVNAPVLEIQEVLKKVSEGHLNVKVKGDYKGDYAELKNALNNTIDTLHSYIEEISR 257
Query: 363 RRIETASGNL---YKEKIIRGFCHLYSGQEAVAVGMRAAMRD 479
E A GNL EK + F H++ + + V + +R+
Sbjct: 258 VLTEMAKGNLDVSLSEKYLGDFAHIHEALDTIIVSLNGMIRE 299
>UniRef50_A0QB51 Cluster: Dehydrogenase E1 component superfamily
protein; n=2; Mycobacterium avium|Rep: Dehydrogenase E1
component superfamily protein - Mycobacterium avium
(strain 104)
Length = 297
Score = 33.9 bits (74), Expect = 2.8
Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Frame = +3
Query: 324 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSV--IT 497
+D L+ Y ++ +LR ++ A I + GQEAVAVG AA+R D V T
Sbjct: 7 DDRLEPYRRMWVLRLLDMALDESAVGAAIDDDAPVDFGQEAVAVGAVAALRPGDLVNATT 66
Query: 498 AYRCHGWTYLMGVSVLGVLSELTGRRTG 581
H +G+ + ++EL G G
Sbjct: 67 PRFRHAQQIGLGLPLGPAIAELLGTTRG 94
>UniRef50_A2FVJ6 Cluster: DnaK protein; n=1; Trichomonas vaginalis
G3|Rep: DnaK protein - Trichomonas vaginalis G3
Length = 726
Score = 33.9 bits (74), Expect = 2.8
Identities = 23/63 (36%), Positives = 34/63 (53%)
Frame = +3
Query: 135 DKMSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSAT 314
D K + +A K LAG +TK+ A + +Y+ K TF KP + +D G A+S T
Sbjct: 161 DSQKKKVSAAIK-LAGLKLTKIIDEKTALSLQYAIDKHDTFVSKPKYVAIIDFG-ASSLT 218
Query: 315 LTS 323
L+S
Sbjct: 219 LSS 221
>UniRef50_UPI0000F2D933 Cluster: PREDICTED: similar to doublecortin
domain containing 5; n=1; Monodelphis domestica|Rep:
PREDICTED: similar to doublecortin domain containing 5 -
Monodelphis domestica
Length = 745
Score = 33.5 bits (73), Expect = 3.8
Identities = 27/103 (26%), Positives = 51/103 (49%), Gaps = 3/103 (2%)
Frame = +3
Query: 93 KDH*IN-LGFIEIIIDKMSKLIP--SAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEI 263
KD IN +G+ + + +K++ + AK L G K P + +K++ F +
Sbjct: 240 KDEEINQVGYYFRLPGRKTKIMVCLACAKSLIGQKEVKKLPPTSKFLCAFGSKEQKQFSL 299
Query: 264 KPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNL 392
K + ++QG AT +EDA++ YE L + + +T++ L
Sbjct: 300 KYLNVIGMNQGDL--ATYEAEDAIRHYEDLLLAFQKKTSTHTL 340
>UniRef50_Q3W421 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp.
EAN1pec|Rep: Pyruvate dehydrogenase - Frankia sp.
EAN1pec
Length = 358
Score = 33.5 bits (73), Expect = 3.8
Identities = 24/91 (26%), Positives = 39/91 (42%)
Frame = +3
Query: 297 PATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 476
P + S Y ++ RR++ + L ++ + + L GQEA VG AA
Sbjct: 31 PRFTVRADSRQTESFYREMVRARRLDEEATALQRQGELVLWIPL-RGQEAAQVGSAAAAE 89
Query: 477 DADSVITAYRCHGWTYLMGVSVLGVLSELTG 569
AD + +YR H + G+ + L L G
Sbjct: 90 PADFLFPSYREHAVVWHRGIPPVEALRLLRG 120
>UniRef50_Q5KGR5 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit, putative; n=2;
Filobasidiella neoformans|Rep: Branched-chain alpha-keto
acid dehydrogenase E1-alpha subunit, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 504
Score = 33.5 bits (73), Expect = 3.8
Identities = 23/85 (27%), Positives = 38/85 (44%)
Frame = +3
Query: 252 TFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLY 431
TF + + H + G + AT E L +Y +T++ ++ ++ I F
Sbjct: 111 TFRVLDEEGHMVKDGHESQAT--KEQTLSIYRTMTLIPIVDNVLYQSQRQGRI-SFYMQC 167
Query: 432 SGQEAVAVGMRAAMRDADSVITAYR 506
+G+EA VG AAM D + YR
Sbjct: 168 AGEEAAIVGSAAAMLANDEIFGQYR 192
>UniRef50_Q6QXE3 Cluster: ORF24; n=1; Agrotis segetum
granulovirus|Rep: ORF24 - Agrotis segetum granulosis
virus (AsGV) (Agrotis segetumgranulovirus)
Length = 362
Score = 32.7 bits (71), Expect = 6.6
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Frame = +3
Query: 225 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDAL--KLYEQLTILRRIETASGNLYK 398
+K K F I+ +++LD+ A A LT L + EQ+T +RRI+ N+
Sbjct: 169 SKKPNKAPVRFYIEDL-INRLDEIIAEPAMLTENIRLIKEKVEQMTTIRRIQ----NIAP 223
Query: 399 EKIIRGFCHLYSGQEAV 449
+K ++ + H+Y G+E +
Sbjct: 224 KKELKSYVHIYVGREVI 240
>UniRef50_A2DM79 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 1353
Score = 32.7 bits (71), Expect = 6.6
Identities = 19/57 (33%), Positives = 28/57 (49%)
Frame = +3
Query: 228 KYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYK 398
+Y+T+K A+F ++ +L KLDQ PA E Y QL L + N Y+
Sbjct: 129 EYNTRKSASFPVRSEELKKLDQPPAIETEFPYEIE---YFQLHYLPAVNILLSNFYE 182
>UniRef50_Q0RLC2 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=2; Bacteria|Rep: Pyruvate dehydrogenase E1
component, alpha subunit - Frankia alni (strain ACN14a)
Length = 342
Score = 32.3 bits (70), Expect = 8.7
Identities = 23/83 (27%), Positives = 35/83 (42%)
Frame = +3
Query: 333 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 512
L L+ T + R + +L I G + GQE A + A +R D V+T YR
Sbjct: 25 LGLFRTATRIARFDEKYRSLMTSGAIGGMYYSPRGQEFAAASVAAHLRRDDYVVTTYRGL 84
Query: 513 GWTYLMGVSVLGVLSELTGRRTG 581
GV + + +E G+ G
Sbjct: 85 HDQIAKGVPLRELWAEYLGKAAG 107
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 548,818,509
Number of Sequences: 1657284
Number of extensions: 10220912
Number of successful extensions: 27705
Number of sequences better than 10.0: 113
Number of HSP's better than 10.0 without gapping: 26921
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 27687
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 40820699206
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -