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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= brP-0019
         (800 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q13630 Cluster: GDP-L-fucose synthetase (EC 1.1.1.271) ...   256   4e-67
UniRef50_A5PHP4 Cluster: GDP-4-dehydro-6-deoxy-D-mannose epimera...   232   7e-60
UniRef50_Q00XZ4 Cluster: GDP-4-keto-6-deoxy-D-mannose epimerase-...   201   1e-50
UniRef50_Q8IJQ5 Cluster: GDP-fucose synthase, putative; n=5; Pla...   157   2e-37
UniRef50_Q74FI1 Cluster: GDP-fucose synthetase; n=7; Bacteria|Re...   127   3e-28
UniRef50_Q0BHR7 Cluster: NAD-dependent epimerase/dehydratase; n=...   120   6e-26
UniRef50_Q2IZX2 Cluster: NAD-dependent epimerase/dehydratase; n=...   119   1e-25
UniRef50_Q4AI76 Cluster: GDP-L-fucose synthase; n=6; Bacteria|Re...   118   2e-25
UniRef50_Q0EXY2 Cluster: GDP-fucose synthetase; n=4; Proteobacte...   117   3e-25
UniRef50_Q0M6J4 Cluster: NAD-dependent epimerase/dehydratase:3-b...   113   4e-24
UniRef50_Q3B1R9 Cluster: GDP-L-fucose synthetase; n=3; Bacteria|...   112   1e-23
UniRef50_Q2RXT6 Cluster: NAD-dependent epimerase/dehydratase; n=...   112   1e-23
UniRef50_Q7BR89 Cluster: GDP-6-deoxy-4-keto-D-mannose-3, 5-epime...   111   2e-23
UniRef50_A7IWS0 Cluster: Putative uncharacterized protein B395L;...   110   3e-23
UniRef50_Q124Z8 Cluster: NAD-dependent epimerase/dehydratase; n=...   110   3e-23
UniRef50_A5ZJL9 Cluster: Putative uncharacterized protein; n=1; ...   110   3e-23
UniRef50_Q8VU14 Cluster: GDP-4-keto-6-deoxy-D-mannose-3, 5-epime...   110   5e-23
UniRef50_Q93N55 Cluster: GDP-4-keto-6 deoxymannose epimerase/red...   109   6e-23
UniRef50_A6VG32 Cluster: NAD-dependent epimerase/dehydratase; n=...   109   6e-23
UniRef50_A4YQ54 Cluster: Bifunctional GDP-fucose synthetase: GDP...   108   1e-22
UniRef50_Q5V3C6 Cluster: DTDP-glucose dehydratase; n=23; cellula...   108   1e-22
UniRef50_Q9XDD7 Cluster: Bme10; n=1; Brucella melitensis|Rep: Bm...   107   4e-22
UniRef50_Q1VHC4 Cluster: GDP-fucose synthetase chain A; n=1; Psy...   105   2e-21
UniRef50_O49213 Cluster: GDP-L-fucose synthase 1; n=181; root|Re...   105   2e-21
UniRef50_Q7MV22 Cluster: GDP-fucose synthetase; n=5; Bacteria|Re...   104   3e-21
UniRef50_A2BXU6 Cluster: Putative fucose synthetase; n=1; Prochl...   100   9e-20
UniRef50_Q8L2G9 Cluster: Fcl; n=2; Enterobacteriaceae|Rep: Fcl -...    99   1e-19
UniRef50_O84974 Cluster: O-antigen biosynthesis protein; n=5; He...    99   1e-19
UniRef50_A1B1K8 Cluster: NAD-dependent epimerase/dehydratase; n=...    98   3e-19
UniRef50_A5GHX4 Cluster: GDP-L fucose synthetase; n=25; Bacteria...    97   6e-19
UniRef50_Q9AQ09 Cluster: Putative nodulation NAD-dependent nucle...    92   1e-17
UniRef50_Q8VQ41 Cluster: WbdJ; n=13; Bacteria|Rep: WbdJ - Escher...    92   2e-17
UniRef50_P33217 Cluster: Nodulation protein nolK; n=2; Alphaprot...    90   7e-17
UniRef50_Q2BI22 Cluster: DTDP-glucose dehydratase; n=1; Neptunii...    87   4e-16
UniRef50_Q67WR5 Cluster: Putative GDP-L-fucose synthase 2; n=4; ...    85   2e-15
UniRef50_A0R4U4 Cluster: NAD dependent epimerase/dehydratase fam...    74   5e-12
UniRef50_Q30CR4 Cluster: LipDig4; n=3; Streptomyces|Rep: LipDig4...    61   3e-08
UniRef50_Q1J353 Cluster: GDP-L-fucose synthase; n=1; Deinococcus...    61   3e-08
UniRef50_Q18EM2 Cluster: Nucleoside-diphosphate-sugar epimerase;...    60   8e-08
UniRef50_A6GLY7 Cluster: Putative uncharacterized protein; n=1; ...    57   4e-07
UniRef50_Q5SKQ2 Cluster: UDP-glucose 4-epimerase; n=4; Thermus|R...    56   8e-07
UniRef50_Q83DA9 Cluster: NAD dependent epimerase/dehydratase fam...    54   4e-06
UniRef50_Q1GN57 Cluster: NAD-dependent epimerase/dehydratase; n=...    54   6e-06
UniRef50_Q55412 Cluster: Slr0583 protein; n=3; Chroococcales|Rep...    53   7e-06
UniRef50_A5GEL7 Cluster: NAD-dependent epimerase/dehydratase pre...    53   1e-05
UniRef50_Q2NIA3 Cluster: Putative UDP-glucose 4-epimerase; n=1; ...    53   1e-05
UniRef50_Q9ZHQ3 Cluster: 4-ketoreductase; n=2; Actinomycetales|R...    50   5e-05
UniRef50_Q9K7I2 Cluster: UDP-glucose 4-epimerase; n=17; cellular...    50   7e-05
UniRef50_A5GIA6 Cluster: NAD dependent epimerase/dehydratase; n=...    50   9e-05
UniRef50_Q12VP0 Cluster: NAD-dependent epimerase/dehydratase; n=...    49   1e-04
UniRef50_Q8DJM2 Cluster: Nucleotide sugar epimerase; n=61; cellu...    48   2e-04
UniRef50_Q5KWG9 Cluster: Nucleotide sugar epimerase; n=1; Geobac...    48   2e-04
UniRef50_O06485 Cluster: YfnG; n=3; Bacteria|Rep: YfnG - Bacillu...    48   2e-04
UniRef50_Q5KUQ5 Cluster: UDP-glucose 4-epimerase; n=5; Bacteria|...    48   4e-04
UniRef50_A5WE41 Cluster: NAD-dependent epimerase/dehydratase; n=...    48   4e-04
UniRef50_A0L5P6 Cluster: UDP-glucose 4-epimerase; n=4; Bacteria|...    48   4e-04
UniRef50_A1SL10 Cluster: NAD-dependent epimerase/dehydratase; n=...    47   6e-04
UniRef50_A2SRX5 Cluster: NAD-dependent epimerase/dehydratase; n=...    47   6e-04
UniRef50_Q9FB21 Cluster: Sugar epimerase BlmG; n=1; Streptomyces...    46   0.001
UniRef50_A5UK04 Cluster: UDP-glucose 4-epimerase; n=2; Euryarcha...    46   0.001
UniRef50_Q0W7F9 Cluster: Putative UDP-glucose 4-epimerase; n=1; ...    46   0.001
UniRef50_Q9ABX8 Cluster: UDP-glucose 4-epimerase; n=1; Caulobact...    45   0.002
UniRef50_Q70PA0 Cluster: Putative uncharacterized protein; n=1; ...    45   0.002
UniRef50_Q9KDV3 Cluster: UDP-glucose 4-epimerase; n=124; cellula...    45   0.002
UniRef50_Q832Q5 Cluster: NAD-dependent epimerase/dehydratase fam...    45   0.003
UniRef50_O54385 Cluster: UDP-glucose epimerase; n=11; cellular o...    45   0.003
UniRef50_A6CLM3 Cluster: UDP-glucose 4-epimerase; n=1; Bacillus ...    45   0.003
UniRef50_O28263 Cluster: UDP-glucose 4-epimerase; n=1; Archaeogl...    45   0.003
UniRef50_A3ERU6 Cluster: Nucleoside-diphosphate-sugar epimerase;...    44   0.003
UniRef50_Q8R8R8 Cluster: UDP-glucose 4-epimerase; n=15; Bacteria...    44   0.004
UniRef50_Q83W21 Cluster: Ata17 protein; n=9; Bacteria|Rep: Ata17...    44   0.004
UniRef50_Q9WYX9 Cluster: UDP-glucose 4-epimerase, putative; n=5;...    44   0.006
UniRef50_Q0C2X5 Cluster: UDP-glucose 4-epimerase; n=1; Hyphomona...    44   0.006
UniRef50_A7HI28 Cluster: NAD-dependent epimerase/dehydratase; n=...    44   0.006
UniRef50_Q8TXF0 Cluster: Nucleoside-diphosphate-sugar epimerase;...    44   0.006
UniRef50_Q8THP9 Cluster: DTDP-glucose 4,6-dehydratase; n=3; Meth...    43   0.008
UniRef50_Q9RWF7 Cluster: UDP-glucose 4-epimerase, putative; n=63...    43   0.010
UniRef50_Q6MF46 Cluster: Probable UDP-glucuronat epimerase; n=2;...    43   0.010
UniRef50_Q9JRN7 Cluster: Putative uncharacterized protein; n=1; ...    43   0.010
UniRef50_A3PE63 Cluster: UDP-glucose 4-epimerase; n=1; Prochloro...    43   0.010
UniRef50_Q9YCT1 Cluster: DTDP-glucose 4,6-dehydratase; n=2; Ther...    43   0.010
UniRef50_A7CY79 Cluster: NAD-dependent epimerase/dehydratase; n=...    42   0.014
UniRef50_Q2SII8 Cluster: Nucleoside-diphosphate-sugar epimerase;...    42   0.018
UniRef50_Q12UG3 Cluster: NAD-dependent epimerase/dehydratase; n=...    42   0.018
UniRef50_Q661H6 Cluster: Nucleotide sugar epimerase; n=3; Borrel...    42   0.024
UniRef50_Q0YI68 Cluster: NAD-dependent epimerase/dehydratase:Sho...    42   0.024
UniRef50_Q5FQW6 Cluster: UDP-glucose 4-epimerase; n=3; Bacteria|...    41   0.032
UniRef50_A6PV21 Cluster: UDP-glucose 4-epimerase; n=1; Victivall...    41   0.032
UniRef50_A0B5G2 Cluster: NAD-dependent epimerase/dehydratase; n=...    41   0.032
UniRef50_Q9LIS3 Cluster: UDP-glucuronate 4-epimerase 6; n=40; Vi...    41   0.032
UniRef50_P72903 Cluster: UDP-glucose-4-epimerase; n=20; Bacteria...    41   0.042
UniRef50_Q1VUQ5 Cluster: Sugar epimerase BlmG; n=2; Bacteria|Rep...    41   0.042
UniRef50_A4CBV8 Cluster: NAD dependent epimerase/dehydratase fam...    40   0.055
UniRef50_O26473 Cluster: DTDP-glucose 4,6-dehydratase related pr...    40   0.055
UniRef50_A7DQX9 Cluster: NAD-dependent epimerase/dehydratase; n=...    40   0.055
UniRef50_Q5FRS4 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=...    40   0.073
UniRef50_Q1VGF9 Cluster: Putative uncharacterized protein; n=1; ...    40   0.073
UniRef50_Q0LJ11 Cluster: NAD-dependent epimerase/dehydratase; n=...    40   0.073
UniRef50_A7GZ40 Cluster: dTDP-glucose 4,6-dehydratase; n=1; Camp...    40   0.073
UniRef50_Q81AP5 Cluster: CDP-abequose synthase; n=2; Bacillus ce...    40   0.096
UniRef50_Q3ESA4 Cluster: DTDP-glucose 4,6-dehydratase; n=3; Firm...    40   0.096
UniRef50_A6DF55 Cluster: Putative uncharacterized protein; n=1; ...    40   0.096
UniRef50_A5M424 Cluster: UDP-glucose 4-epimerase; n=1; Streptoco...    40   0.096
UniRef50_Q18EM3 Cluster: Nucleoside-diphosphate-sugar epimerase;...    39   0.13 
UniRef50_Q1YMT2 Cluster: UDP-glucose 4-epimerase; n=3; Alphaprot...    39   0.17 
UniRef50_Q93VR3 Cluster: GDP-mannose 3,5-epimerase; n=21; cellul...    39   0.17 
UniRef50_Q42605 Cluster: UDP-glucose 4-epimerase; n=20; Viridipl...    39   0.17 
UniRef50_UPI0000DAE763 Cluster: hypothetical protein Rgryl_01001...    38   0.22 
UniRef50_Q9RSC3 Cluster: UDP-glucose 4-epimerase; n=1; Deinococc...    38   0.22 
UniRef50_Q65E95 Cluster: Putative uncharacterized protein; n=1; ...    38   0.22 
UniRef50_Q2WB63 Cluster: Nucleoside-diphosphate-sugar epimerase;...    38   0.22 
UniRef50_Q8GP51 Cluster: Eps11G; n=11; Bacteria|Rep: Eps11G - St...    38   0.22 
UniRef50_Q7D561 Cluster: NAD-dependent epimerase/dehydratase fam...    38   0.22 
UniRef50_Q4HQ86 Cluster: UDP-glucose 4-epimerase, putative; n=2;...    38   0.22 
UniRef50_Q7WNH4 Cluster: Putative NAD dependent epimerase/dehydr...    38   0.29 
UniRef50_Q1FJC1 Cluster: DTDP-glucose 4,6-dehydratase; n=1; Clos...    38   0.29 
UniRef50_Q11WU7 Cluster: UDP-galactose-4-epimerase; n=1; Cytopha...    38   0.29 
UniRef50_A1GFD2 Cluster: NAD-dependent epimerase/dehydratase; n=...    38   0.29 
UniRef50_Q5UXR0 Cluster: UDP-glucose 4-epimerase; n=3; Halobacte...    38   0.29 
UniRef50_A6GG02 Cluster: Putative uncharacterized protein; n=1; ...    38   0.39 
UniRef50_Q8WUS8 Cluster: HSPC105 protein; n=21; Euteleostomi|Rep...    38   0.39 
UniRef50_Q2FS05 Cluster: NAD-dependent epimerase/dehydratase; n=...    38   0.39 
UniRef50_Q982P5 Cluster: UDP-glucose 4-epimerase; n=1; Mesorhizo...    37   0.51 
UniRef50_Q8ECF4 Cluster: DTDP-glucose 4,6-dehydratase; n=18; Gam...    37   0.51 
UniRef50_Q1QD53 Cluster: NAD-dependent epimerase/dehydratase; n=...    37   0.51 
UniRef50_Q0BRM8 Cluster: UDP-glucose 4-epimerase; n=2; Rhodospir...    37   0.51 
UniRef50_A6GE58 Cluster: NAD-dependent epimerase/dehydratase fam...    37   0.51 
UniRef50_A4QBQ0 Cluster: Putative uncharacterized protein; n=1; ...    37   0.51 
UniRef50_Q57664 Cluster: Putative UDP-glucose 4-epimerase; n=3; ...    37   0.51 
UniRef50_Q7UXZ2 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=...    37   0.68 
UniRef50_A6Q4T4 Cluster: NAD-dependent epimerase/dehydratase; n=...    37   0.68 
UniRef50_A3ERM8 Cluster: UDP-glucose 4-epimerase; n=1; Leptospir...    37   0.68 
UniRef50_A6SIX9 Cluster: Putative uncharacterized protein; n=1; ...    37   0.68 
UniRef50_Q5V6W4 Cluster: UDP-glucose 4-epimerase; n=1; Haloarcul...    37   0.68 
UniRef50_Q65D61 Cluster: Putative uncharacterized protein; n=1; ...    36   0.90 
UniRef50_A3Q712 Cluster: UDP-glucose 4-epimerase; n=6; Actinobac...    36   0.90 
UniRef50_Q2FKD1 Cluster: NAD-dependent epimerase/dehydratase fam...    36   1.2  
UniRef50_Q1GKR7 Cluster: UDP-glucose 4-epimerase; n=17; Bacteria...    36   1.2  
UniRef50_P14169 Cluster: CDP-paratose 2-epimerase; n=12; cellula...    36   1.2  
UniRef50_UPI0001597850 Cluster: hypothetical protein RBAM_031220...    36   1.6  
UniRef50_Q97KX2 Cluster: Nucleoside-diphosphate-sugar epimerase;...    36   1.6  
UniRef50_Q8RGC6 Cluster: UDP-glucose 4-epimerase; n=2; Fusobacte...    36   1.6  
UniRef50_A7DIX5 Cluster: NAD-dependent epimerase/dehydratase; n=...    36   1.6  
UniRef50_A6PTX1 Cluster: NAD-dependent epimerase/dehydratase; n=...    36   1.6  
UniRef50_A6BZU3 Cluster: Putative uncharacterized protein; n=1; ...    36   1.6  
UniRef50_A3H6D1 Cluster: NAD-dependent epimerase/dehydratase; n=...    36   1.6  
UniRef50_Q8KNN2 Cluster: DTDP-D-glucose-4,6-dehydratase; n=4; Ba...    35   2.1  
UniRef50_A7HN54 Cluster: Polysaccharide biosynthesis protein Cap...    35   2.1  
UniRef50_A6CEQ2 Cluster: Putative uncharacterized protein; n=1; ...    35   2.7  
UniRef50_A0LGE9 Cluster: NAD-dependent epimerase/dehydratase; n=...    35   2.7  
UniRef50_Q8ZW82 Cluster: UDP-glucose 4-epimerase; n=6; Thermopro...    35   2.7  
UniRef50_P18645 Cluster: UDP-glucose 4-epimerase; n=353; cellula...    35   2.7  
UniRef50_Q7CS52 Cluster: AGR_L_3011p; n=3; Alphaproteobacteria|R...    34   3.6  
UniRef50_Q1YQ08 Cluster: Oxidoreductase; n=1; gamma proteobacter...    34   3.6  
UniRef50_A7I3Y2 Cluster: Putative zinc protease; n=1; Campylobac...    34   3.6  
UniRef50_A4BBD6 Cluster: Putative uncharacterized protein; n=1; ...    34   3.6  
UniRef50_A1IBU5 Cluster: Nucleoside-diphosphate-sugar epimerases...    34   3.6  
UniRef50_Q868I5 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=...    34   3.6  
UniRef50_Q54WS6 Cluster: Putative dTDP-D-glucose 4,6-dehydratase...    34   3.6  
UniRef50_A0BCG5 Cluster: Chromosome undetermined scaffold_10, wh...    34   3.6  
UniRef50_A3LR65 Cluster: Putative dtdp-glucose 4,6-dehydratase; ...    34   3.6  
UniRef50_Q59083 Cluster: UDP-glucose 4-epimerase; n=14; Bacteria...    34   3.6  
UniRef50_Q2JCE7 Cluster: DTDP-glucose 4,6-dehydratase; n=5; Bact...    34   4.8  
UniRef50_Q01T66 Cluster: DTDP-glucose 4,6-dehydratase precursor;...    34   4.8  
UniRef50_A7HHX8 Cluster: NAD-dependent epimerase/dehydratase; n=...    34   4.8  
UniRef50_A6H035 Cluster: GDP-4-dehydro-D-rhamnose reductase; n=1...    34   4.8  
UniRef50_A3DIS0 Cluster: Polysaccharide biosynthesis protein Cap...    34   4.8  
UniRef50_A3CKR6 Cluster: Nucleoside-diphosphate-sugar epimerase,...    34   4.8  
UniRef50_A0UVI4 Cluster: NAD-dependent epimerase/dehydratase; n=...    34   4.8  
UniRef50_A0L9M4 Cluster: NAD-dependent epimerase/dehydratase; n=...    34   4.8  
UniRef50_Q5DAK3 Cluster: SJCHGC01535 protein; n=2; Schistosoma j...    34   4.8  
UniRef50_Q814Z6 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=...    33   6.3  
UniRef50_Q7VRZ4 Cluster: Thymidine diphosphoglucose 4,6-dehydrat...    33   6.3  
UniRef50_Q1MP11 Cluster: Nucleoside-diphosphate-sugar epimerases...    33   6.3  
UniRef50_A5N5N5 Cluster: Predicted nucleoside-diphosphate-sugar ...    33   6.3  
UniRef50_A3ZSY0 Cluster: CDP glucose 4,6-dehydratase; n=1; Blast...    33   6.3  
UniRef50_Q9HSU9 Cluster: GDP-D-mannose dehydratase; n=2; Halobac...    33   6.3  
UniRef50_A4FIG8 Cluster: Modular polyketide synthase; n=1; Sacch...    33   8.4  
UniRef50_Q2U1I6 Cluster: Polyketide synthase modules and related...    33   8.4  
UniRef50_A5DWB0 Cluster: Putative uncharacterized protein; n=2; ...    33   8.4  
UniRef50_A2R6J0 Cluster: Catalytic activity: dTDPglucose = dTDP-...    33   8.4  
UniRef50_O95455 Cluster: dTDP-D-glucose 4,6-dehydratase; n=24; E...    33   8.4  

>UniRef50_Q13630 Cluster: GDP-L-fucose synthetase (EC 1.1.1.271)
           (Protein FX) (Red cell NADP(H)- binding protein); n=59;
           Eukaryota|Rep: GDP-L-fucose synthetase (EC 1.1.1.271)
           (Protein FX) (Red cell NADP(H)- binding protein) - Homo
           sapiens (Human)
          Length = 321

 Score =  256 bits (628), Expect = 4e-67
 Identities = 111/167 (66%), Positives = 133/167 (79%)
 Frame = +2

Query: 194 ETWIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSIND 373
           E W+F  SKD DL D  QT ALF K +PTHVIHLAAMVGGLF N+ +NLDF+R+N+ +ND
Sbjct: 36  EDWVFVSSKDADLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMND 95

Query: 374 NILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNR 553
           N+L +  +   +KVVSCLSTCIFPDKTTYPIDETM+HNGPPH+SNFGYSYAKRMIDV NR
Sbjct: 96  NVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNR 155

Query: 554 GYNESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKG 694
            Y + YGC FT+VIP NVFGPHDNF+++  HV+P LI ++  A   G
Sbjct: 156 AYFQQYGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSG 202



 Score = 41.9 bits (94), Expect = 0.018
 Identities = 16/22 (72%), Positives = 18/22 (81%)
 Frame = +1

Query: 715 WGSGKPLRQFIYSLXLGELFIW 780
           WG+G P RQFIYSL L +LFIW
Sbjct: 208 WGTGNPRRQFIYSLDLAQLFIW 229


>UniRef50_A5PHP4 Cluster: GDP-4-dehydro-6-deoxy-D-mannose
           epimerase/reductase; n=2; Trypanosoma brucei|Rep:
           GDP-4-dehydro-6-deoxy-D-mannose epimerase/reductase -
           Trypanosoma brucei brucei
          Length = 358

 Score =  232 bits (568), Expect = 7e-60
 Identities = 103/177 (58%), Positives = 130/177 (73%)
 Frame = +2

Query: 170 KRNSDYDSETWIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFF 349
           KRN+  D E W+F    D DLR    T  +F +HKPTHV+HLAA VGGLF NMA  ++ +
Sbjct: 66  KRNACAD-ERWVFLSRHDADLRSMAATRCVFERHKPTHVLHLAARVGGLFKNMAAPVEMW 124

Query: 350 RENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAK 529
            +N+SIN+N+L+ C  Y V+K VSCLSTCIFP++ TYPI E  +H+GPPH SN  Y+YAK
Sbjct: 125 IDNVSINNNVLECCRTYGVRKAVSCLSTCIFPERATYPIGEETLHDGPPHYSNEQYAYAK 184

Query: 530 RMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDP 700
           RMIDVLNR YN+ YGC FTSVIP NV+GPHDN++L+ SHVIP LI +   A ++  P
Sbjct: 185 RMIDVLNRAYNKEYGCRFTSVIPTNVYGPHDNYNLQDSHVIPGLIHKFYLAKRENKP 241



 Score = 35.9 bits (79), Expect = 1.2
 Identities = 13/21 (61%), Positives = 17/21 (80%)
 Frame = +1

Query: 718 GSGKPLRQFIYSLXLGELFIW 780
           G+G+PLRQF+YS  L EL +W
Sbjct: 246 GTGRPLRQFVYSEDLAELIVW 266


>UniRef50_Q00XZ4 Cluster: GDP-4-keto-6-deoxy-D-mannose
           epimerase-reductase; n=1; Ostreococcus tauri|Rep:
           GDP-4-keto-6-deoxy-D-mannose epimerase-reductase -
           Ostreococcus tauri
          Length = 252

 Score =  201 bits (491), Expect = 1e-50
 Identities = 105/197 (53%), Positives = 126/197 (63%), Gaps = 35/197 (17%)
 Frame = +2

Query: 215 SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMA--------------------- 331
           S+D +L D   T A+F K+KPTHVIHLAA VGGLF NM                      
Sbjct: 14  SQDANLCDPESTAAMFDKYKPTHVIHLAAQVGGLFANMVRAKRRERSNRIATDIRAFVFP 73

Query: 332 ---HNLDFFRENMSINDNILQACHKYN-----------VKKVVSCLSTCIFPDKTTYPID 469
              + ++F+R N+++NDNI Q CHK             V+K+VSCLSTCIFPDKTT+PID
Sbjct: 74  PQKYKVEFWRNNIAMNDNIFQECHKRGTLAWIAINITRVQKLVSCLSTCIFPDKTTFPID 133

Query: 470 ETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKSSHV 649
           ETM+HNGPPH SN GY+YAKRM+DV NR Y   +GC FT+VIP N+FG HDNF L  SHV
Sbjct: 134 ETMIHNGPPHFSNEGYAYAKRMVDVQNRMYKAQHGCNFTAVIPTNIFGKHDNFHLDDSHV 193

Query: 650 IPALIRRMDDAMQKGDP 700
           IP LI R     QKG+P
Sbjct: 194 IPGLIHRGYLCKQKGEP 210



 Score = 42.3 bits (95), Expect = 0.014
 Identities = 17/22 (77%), Positives = 17/22 (77%)
 Frame = +1

Query: 715 WGSGKPLRQFIYSLXLGELFIW 780
           WGSGKPLRQFIYS  L  L IW
Sbjct: 214 WGSGKPLRQFIYSTDLARLMIW 235


>UniRef50_Q8IJQ5 Cluster: GDP-fucose synthase, putative; n=5;
           Plasmodium|Rep: GDP-fucose synthase, putative -
           Plasmodium falciparum (isolate 3D7)
          Length = 329

 Score =  157 bits (382), Expect = 2e-37
 Identities = 73/181 (40%), Positives = 119/181 (65%), Gaps = 4/181 (2%)
 Frame = +2

Query: 143 KTVIERDRQ---KRNSDYDSET-WIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVG 310
           K +IE++ +     N + +  T +IF  S+  DL+D  +++ +F K+  T +IH AA VG
Sbjct: 27  KNIIEKENEIIVNSNENKNIITKYIFLSSEMCDLKDYDKSKLVFEKYNFTDIIHFAAHVG 86

Query: 311 GLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNG 490
           GL+ N  +NLDF   N+ I+ N+++ CHKY++ + +  LSTCIFP   + P+ E  +H+G
Sbjct: 87  GLYANKNNNLDFLINNLEISMNVIKLCHKYSISRGIFTLSTCIFPVNCSLPLTEEKIHDG 146

Query: 491 PPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRR 670
             H SN GYS +KR+++VL R Y E Y   +  +IP N++G +DNF+L+++HVIP++I +
Sbjct: 147 KCHQSNEGYSVSKRVLEVLVRFYREKYNYEWICIIPTNIYGKYDNFNLENAHVIPSIIHK 206

Query: 671 M 673
           M
Sbjct: 207 M 207


>UniRef50_Q74FI1 Cluster: GDP-fucose synthetase; n=7; Bacteria|Rep:
           GDP-fucose synthetase - Geobacter sulfurreducens
          Length = 314

 Score =  127 bits (307), Expect = 3e-28
 Identities = 62/159 (38%), Positives = 91/159 (57%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           DLRD+    A FA  +P +V   AA VGG+  N  +  +F  +N+ I  N++ + ++  V
Sbjct: 41  DLRDQAAVAAFFAAEQPDYVFLAAAKVGGIVANNTYPAEFIYDNLMIEANVIHSSYRTGV 100

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586
            K++   STCI+P   + PI E  +  GP   +N  Y+ AK     L R YN  YG  F 
Sbjct: 101 SKLLFLGSTCIYPKMASQPIREEYLLTGPLEPTNEAYAIAKIAGISLCRSYNRQYGTRFI 160

Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPT 703
           + +P N++GP+DNF L+ SHV+PALIR+  +A   G PT
Sbjct: 161 AAMPTNLYGPNDNFDLEKSHVLPALIRKFHEAKIAGAPT 199


>UniRef50_Q0BHR7 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Burkholderia ambifaria AMMD|Rep: NAD-dependent
           epimerase/dehydratase - Burkholderia cepacia (strain
           ATCC 53795 / AMMD)
          Length = 311

 Score =  120 bits (288), Expect = 6e-26
 Identities = 59/162 (36%), Positives = 91/162 (56%)
 Frame = +2

Query: 215 SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 394
           S D DLRD++ TE +F + +PT V H+AA V G+  NM++    + +N+ IN N+++A  
Sbjct: 38  SSDIDLRDQSATEKMFDELRPTIVFHMAARVYGIMGNMSNRGIAYLDNVRINTNVVEAAR 97

Query: 395 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574
           +   KK V+  ST I+ D+   P+ E  +  G PH S   Y+++KR +      Y + YG
Sbjct: 98  QTGCKKFVAMGSTAIYSDQVRLPMSEEQIWVGAPHHSEAPYAHSKRGMLAQLEAYKDQYG 157

Query: 575 CMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDP 700
             +   +  N+FGPHD F  K  HVIP+L+ +   A   G P
Sbjct: 158 MDYAFCVSTNLFGPHDKFDEKFGHVIPSLVSKFYRASVLGQP 199


>UniRef50_Q2IZX2 Cluster: NAD-dependent epimerase/dehydratase; n=4;
           Alphaproteobacteria|Rep: NAD-dependent
           epimerase/dehydratase - Rhodopseudomonas palustris
           (strain HaA2)
          Length = 337

 Score =  119 bits (286), Expect = 1e-25
 Identities = 59/161 (36%), Positives = 90/161 (55%)
 Frame = +2

Query: 212 GSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC 391
           G  + DLR +T+ +  F+  +P  VI  AA VGG+  N  +   F  +N+SI DN++Q+ 
Sbjct: 41  GRDELDLRHQTKVQEWFSSERPDVVILAAARVGGVLANSKYPASFLSDNLSIQDNVIQSA 100

Query: 392 HKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESY 571
               VKK++   S+C++P   + PI+E  +  G    +N  Y  AK    +    Y E Y
Sbjct: 101 AAAGVKKLLFVSSSCVYPRLASQPIEEDALLTGALEPTNRWYGVAKIAGMMQCAAYREQY 160

Query: 572 GCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKG 694
           GC F + +P N++GP D F  ++SHVIPA +RR  DA+  G
Sbjct: 161 GCDFIAAVPGNLYGPGDYFDKENSHVIPAFLRRFHDAVTTG 201


>UniRef50_Q4AI76 Cluster: GDP-L-fucose synthase; n=6; Bacteria|Rep:
           GDP-L-fucose synthase - Chlorobium phaeobacteroides BS1
          Length = 402

 Score =  118 bits (283), Expect = 2e-25
 Identities = 58/149 (38%), Positives = 87/149 (58%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           DLR+    +  F + KP +VI  AA VGG+  N  +  DF  EN+ I  N++   +   V
Sbjct: 41  DLRNTMAVKTFFEREKPEYVILAAAKVGGIVANNTYRADFIYENLMIQSNVIHQSYLSGV 100

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586
           KK++   STCI+P +   P+ E  +   P   +N  Y+ AK     +   YN  YG  F 
Sbjct: 101 KKLLFLGSTCIYPKECPQPMKEEHLLTSPLEYTNEPYAIAKIAGIKMCESYNIQYGTNFI 160

Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRM 673
           SV+P N++GP+DNF+L++SHV+PALIR++
Sbjct: 161 SVMPTNLYGPNDNFNLETSHVLPALIRKI 189


>UniRef50_Q0EXY2 Cluster: GDP-fucose synthetase; n=4;
           Proteobacteria|Rep: GDP-fucose synthetase -
           Mariprofundus ferrooxydans PV-1
          Length = 371

 Score =  117 bits (282), Expect = 3e-25
 Identities = 60/173 (34%), Positives = 98/173 (56%), Gaps = 2/173 (1%)
 Frame = +2

Query: 185 YDSETWIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMS 364
           +  E+ +   S + DLR++   +A FA  +P +V   AA VGG++ N  +  DF R+N+ 
Sbjct: 43  HSPESLVLRTSSELDLRNQAAVDAFFALERPEYVFLAAAKVGGIYANDTYPADFIRDNLQ 102

Query: 365 INDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDV 544
           I  N++ A +   VK+++   S+CI+P     P+ E+ +  G    +N  Y+ AK     
Sbjct: 103 IQTNVIDAAYSNGVKRLLFLGSSCIYPKLAPQPMPESCLLTGELEPTNEWYAIAKIAGIK 162

Query: 545 LNRGYNESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDA--MQKGD 697
           + + Y++ YG    S +P N++GP+DNF L+ SHV+PALIR+   A   Q GD
Sbjct: 163 MCQAYHKQYGFDAISAMPTNLYGPNDNFDLEKSHVLPALIRKFHLAKLAQAGD 215


>UniRef50_Q0M6J4 Cluster: NAD-dependent epimerase/dehydratase:3-beta
           hydroxysteroid
           dehydrogenase/isomerase:dTDP-4-dehydrorhamnose
           reductase:Male sterility-like; n=1; Caulobacter sp.
           K31|Rep: NAD-dependent epimerase/dehydratase:3-beta
           hydroxysteroid
           dehydrogenase/isomerase:dTDP-4-dehydrorhamnose
           reductase:Male sterility-like - Caulobacter sp. K31
          Length = 316

 Score =  113 bits (273), Expect = 4e-24
 Identities = 59/160 (36%), Positives = 85/160 (53%)
 Frame = +2

Query: 215 SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 394
           S DGDL     T AL  + +P  VIHLAA  GG+  N +   DF+  N+++  N+ +A  
Sbjct: 36  SADGDLTSFDVTRALLERVRPDAVIHLAAYSGGIGANRSWPADFYWRNITLVSNMYEAAA 95

Query: 395 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574
           +  VK++V  +  C +P   T PI E  +  G P   +  YS AK+M  V  + Y   +G
Sbjct: 96  QTGVKRIVYTMGGCSYPGTATSPISEDQMWEGYPQGDSAAYSAAKKMGIVAAKAYEAQHG 155

Query: 575 CMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKG 694
              T ++P N+FG  DN+    SHVIPA +RR  +A   G
Sbjct: 156 ISSTVLVPGNLFGEFDNYRNGESHVIPAFLRRFHEAKLNG 195


>UniRef50_Q3B1R9 Cluster: GDP-L-fucose synthetase; n=3;
           Bacteria|Rep: GDP-L-fucose synthetase - Pelodictyon
           luteolum (strain DSM 273) (Chlorobium luteolum (strain
           DSM273))
          Length = 319

 Score =  112 bits (269), Expect = 1e-23
 Identities = 58/181 (32%), Positives = 96/181 (53%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           DL ++   +  F+  KP  V   AA VGG+  N  +  +F  +N+ +  N++ A ++  V
Sbjct: 41  DLTNQAAVQDFFSTEKPDQVYLAAAKVGGIHANNTYPAEFIYQNLMVECNVIDAAYRNGV 100

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586
           +K++   S+CI+P +   P+ E  +  G    +N  Y+ AK     L   YN  YG  + 
Sbjct: 101 EKLLFLGSSCIYPKQAPQPMRENALLTGVLEPTNEPYAIAKIAGIKLCESYNRQYGTDYR 160

Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXISA 766
           SV+P N++GP DN+  ++SHVIPALIRR  +A     PT    G      + L++  ++A
Sbjct: 161 SVMPTNLYGPGDNYHPENSHVIPALIRRFHEATVGNAPTVTIWGSGTPRREFLYVDDMAA 220

Query: 767 S 769
           +
Sbjct: 221 A 221


>UniRef50_Q2RXT6 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Proteobacteria|Rep: NAD-dependent epimerase/dehydratase
           - Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255)
          Length = 329

 Score =  112 bits (269), Expect = 1e-23
 Identities = 55/161 (34%), Positives = 90/161 (55%)
 Frame = +2

Query: 212 GSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC 391
           G +D DL  +   EA    ++P  V+  AA+VGG+  N   + +F  +N+++  NI+ A 
Sbjct: 52  GREDLDLTRQQAVEAWMEANRPDAVVMAAALVGGIKANDRRSAEFIHQNLAVQTNIIHAA 111

Query: 392 HKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESY 571
            +  V KV+   S+CI+P     P+ E  + +GP   +N  Y+ AK     + + Y   Y
Sbjct: 112 WQAGVGKVLFLGSSCIYPRDVAQPMREDALLSGPLEPTNQWYAIAKIAGIRMAQAYRRQY 171

Query: 572 GCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKG 694
           GC + S +P N++GP DNF L   HV+PAL+R++ +A  +G
Sbjct: 172 GCDYISAMPTNLYGPGDNFDLDGGHVLPALLRKIHEAKVEG 212


>UniRef50_Q7BR89 Cluster: GDP-6-deoxy-4-keto-D-mannose-3,
           5-epimerase-4-reductase merA; n=4; Mycobacterium
           avium|Rep: GDP-6-deoxy-4-keto-D-mannose-3,
           5-epimerase-4-reductase merA - Mycobacterium avium
          Length = 339

 Score =  111 bits (267), Expect = 2e-23
 Identities = 59/184 (32%), Positives = 94/184 (51%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           DL D+  T    ++ +P  +I  AA VGG+  N  +  DF  EN+ I  N+L A     V
Sbjct: 67  DLTDRAATFDFVSETRPQVIIDAAARVGGIMANNTYPADFLSENLRIQTNLLDAAVAVRV 126

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586
            +++   S+CI+P     PI E+ +  GP   +N  Y+ AK    +  +     YG  + 
Sbjct: 127 PRLLFLGSSCIYPKYAPQPIHESALLTGPLEPTNDAYAIAKIAGILQVQAVRRQYGLAWI 186

Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXISA 766
           S +P N++GP DNFS   SH++PALIRR ++A   G     + G      + L +  +++
Sbjct: 187 SAMPTNLYGPGDNFSPSGSHLLPALIRRYEEAKAGGAEEVTNWGTGTPRRELLHVDDLAS 246

Query: 767 SCSF 778
           +C F
Sbjct: 247 ACLF 250


>UniRef50_A7IWS0 Cluster: Putative uncharacterized protein B395L;
           n=3; Chlorovirus|Rep: Putative uncharacterized protein
           B395L - Paramecium bursaria Chlorella virus NY2A
           (PBCV-NY2A)
          Length = 320

 Score =  110 bits (265), Expect = 3e-23
 Identities = 58/163 (35%), Positives = 86/163 (52%)
 Frame = +2

Query: 215 SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 394
           SKD DL ++ +  A F    P +V   AA VGG+  N +   DF  +N+ I  N++ A  
Sbjct: 37  SKDLDLTNQREVNAFFEIELPEYVFLAAAKVGGIHANNSFGGDFIHDNLMIQTNVIHASK 96

Query: 395 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574
            + VKK+V   S+CI+P +   PI E  +  G    +N  Y+ AK     +   Y + YG
Sbjct: 97  MFGVKKLVFLGSSCIYPKEAQNPIKEEYLMTGFLEPTNKPYAIAKIAGIEMCDAYRKQYG 156

Query: 575 CMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPT 703
           C F SV+P N+ GP+D + L + HV P LIR+  +A     P+
Sbjct: 157 CNFVSVMPTNLSGPNDRYDLNNGHVFPVLIRKFCEAKVHNVPS 199


>UniRef50_Q124Z8 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Betaproteobacteria|Rep: NAD-dependent
           epimerase/dehydratase - Polaromonas sp. (strain JS666 /
           ATCC BAA-500)
          Length = 331

 Score =  110 bits (265), Expect = 3e-23
 Identities = 56/187 (29%), Positives = 93/187 (49%)
 Frame = +2

Query: 203 IFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNIL 382
           + +  ++ DL D++       +++P  + H+ A VGG+  N     DF   N+ I  N++
Sbjct: 47  LLTSRQELDLSDQSAVFNWVDENRPELIFHVGAKVGGIHANSTLPADFLYSNLMIQSNVI 106

Query: 383 QACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYN 562
            A H +  KK+V   S C +P KT  PI E  +  GP   +   Y+ +K     + R Y 
Sbjct: 107 NAAHLFGAKKLVFVASNCTYPTKTAQPIPEEALMTGPLDENIRAYAISKIAGIEMCRAYR 166

Query: 563 ESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDS 742
           + YG  F SVIP N++GP DN+  + SHV+  ++RR  +A   G   F   G+     + 
Sbjct: 167 KQYGSNFISVIPPNLYGPGDNYHPQHSHVVAGILRRTHEAKLAGKSEFVVWGDGTPRREL 226

Query: 743 LFIHXIS 763
           L +  ++
Sbjct: 227 LHVDDLA 233


>UniRef50_A5ZJL9 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides caccae ATCC 43185|Rep: Putative
           uncharacterized protein - Bacteroides caccae ATCC 43185
          Length = 358

 Score =  110 bits (265), Expect = 3e-23
 Identities = 56/162 (34%), Positives = 92/162 (56%), Gaps = 2/162 (1%)
 Frame = +2

Query: 218 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 397
           K+ DL D    +  F +  P  V+  AA VGG+  N+ +  DF  +N+ I  N++    +
Sbjct: 38  KELDLLDGVAVKQFFDEELPDAVVLAAAHVGGIMANLQYRADFIYQNLQIQQNVIGESFR 97

Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577
           +NVKK++   STCI+P     P+ E  +   P   +N  Y+ AK     +   +N  YG 
Sbjct: 98  HNVKKLLFLGSTCIYPRDVAQPMKEDALLTSPLEYTNEPYAIAKIAGLKMCESFNLQYGT 157

Query: 578 MFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDA--MQKGD 697
            + +V+P N++GP+DNF L++SHV+PA+IR++  A  + +GD
Sbjct: 158 NYIAVMPTNLYGPNDNFHLENSHVLPAMIRKIHLAKCLNEGD 199


>UniRef50_Q8VU14 Cluster: GDP-4-keto-6-deoxy-D-mannose-3,
           5-epimerase-4-reductase; n=32; Bacteria|Rep:
           GDP-4-keto-6-deoxy-D-mannose-3, 5-epimerase-4-reductase
           - Bacteroides fragilis
          Length = 360

 Score =  110 bits (264), Expect = 5e-23
 Identities = 56/162 (34%), Positives = 91/162 (56%), Gaps = 2/162 (1%)
 Frame = +2

Query: 218 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 397
           K+ DL D    +  F +  P +V   AA VGG+  N  +  DF  +N+ I  N++    +
Sbjct: 42  KELDLLDGATVKQFFDEEMPEYVFLAAAFVGGIMANSIYRADFIYKNLQIQQNVIGESFR 101

Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577
           + VKK++   STCI+P     P+ E ++   P   +N  Y+ AK     +   +N  YG 
Sbjct: 102 HQVKKLLFLGSTCIYPRDAEQPMKEDVLLTSPLEYTNEPYAIAKIAGLKMCESFNLQYGT 161

Query: 578 MFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDA--MQKGD 697
            + +V+P N++GP+DNF L+ SHV+PA+IR++  A  ++KGD
Sbjct: 162 NYIAVMPTNLYGPNDNFDLERSHVLPAMIRKVHLAHCLKKGD 203


>UniRef50_Q93N55 Cluster: GDP-4-keto-6 deoxymannose
           epimerase/reductase; n=2; Coxiella burnetii|Rep:
           GDP-4-keto-6 deoxymannose epimerase/reductase - Coxiella
           burnetii
          Length = 332

 Score =  109 bits (263), Expect = 6e-23
 Identities = 55/182 (30%), Positives = 97/182 (53%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           DL +K +    FA + P +V   AA VGG+  +  H +DF R+N++I  N+++A  +Y V
Sbjct: 41  DLTNKEKVFEFFANNCPEYVFLAAARVGGINDSNLHPVDFIRDNLAIQWNVIEASFRYKV 100

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586
           K+++   S+CI+ +    P+ E   ++G    +N  YS AK         YN  Y   + 
Sbjct: 101 KRLLFLGSSCIYSNDAPRPLKEIYFNSGKLEPTNRAYSTAKIAGIEHCWAYNRQYKTQYL 160

Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXISA 766
             +P N+FGP+DN+ L++ HV+ +LI ++  A ++  P F   G      + L+   ++ 
Sbjct: 161 CAMPTNLFGPNDNYDLENGHVVASLISKIHQAKEQKKPNFVLWGSGKAKREFLYSDDLAE 220

Query: 767 SC 772
           +C
Sbjct: 221 AC 222


>UniRef50_A6VG32 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Methanococcus maripaludis C7|Rep: NAD-dependent
           epimerase/dehydratase - Methanococcus maripaludis C7
          Length = 307

 Score =  109 bits (263), Expect = 6e-23
 Identities = 59/192 (30%), Positives = 97/192 (50%), Gaps = 1/192 (0%)
 Frame = +2

Query: 206 FSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQ 385
           +  SK  +L DK Q E      KP ++  +A +VGG++ NM  N DF  +N  +  N+L+
Sbjct: 34  YPSSKSVNLLDKNQVEEYIKSEKPEYLFMVAGLVGGIYGNMKRNADFLYQNSIMILNVLE 93

Query: 386 ACHKYNVK-KVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYN 562
           +    +   K++   STCI+P +   PI E  + NG    SN GY+ AK +  V    Y 
Sbjct: 94  SIKNCSKDTKILYTGSTCIYPKENPQPISENRLLNGLLEESNKGYALAKILGIVGCELYK 153

Query: 563 ESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDS 742
           + YG     V+P N++GP+D + L+  H IP+LI++  DA           G      ++
Sbjct: 154 KQYGINSICVMPTNMYGPNDTYDLEDGHFIPSLIKKFVDAKNNNLKELTFWGTGIPRREA 213

Query: 743 LFIHXISASCSF 778
           L++   + +C +
Sbjct: 214 LYVDDCADACIY 225


>UniRef50_A4YQ54 Cluster: Bifunctional GDP-fucose synthetase:
           GDP-4-dehydro-6-deoxy-D-mannose epimerase;
           GDP-4-dehydro-6-L-deoxygalactose reductase; n=17;
           root|Rep: Bifunctional GDP-fucose synthetase:
           GDP-4-dehydro-6-deoxy-D-mannose epimerase;
           GDP-4-dehydro-6-L-deoxygalactose reductase -
           Bradyrhizobium sp. (strain ORS278)
          Length = 318

 Score =  108 bits (260), Expect = 1e-22
 Identities = 59/182 (32%), Positives = 92/182 (50%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           DL D+    A FA+ KP  V   AA VGG+  N     +F  +N++I  N++ A H   V
Sbjct: 46  DLSDQAAVFAWFARAKPQVVFLAAAKVGGIVANNTLRAEFIYDNIAIATNVIHAAHVNGV 105

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586
           +K++   S+CI+P     P+ E  +  GP   +N  Y+ AK     +   Y   YG  F 
Sbjct: 106 EKLMFLGSSCIYPKLAAQPLREDAMLTGPLEPTNEPYAIAKIAGIKMVEAYRSQYGADFI 165

Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXISA 766
           +V+P N++GP DN+  + SHV+ ALIRR  +A     P     G      + L++  ++ 
Sbjct: 166 NVMPTNLYGPGDNYHPEYSHVVAALIRRFHEAKLADAPEVIVWGTGKPRREFLYVDDMAD 225

Query: 767 SC 772
           +C
Sbjct: 226 AC 227


>UniRef50_Q5V3C6 Cluster: DTDP-glucose dehydratase; n=23; cellular
           organisms|Rep: DTDP-glucose dehydratase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 333

 Score =  108 bits (260), Expect = 1e-22
 Identities = 54/179 (30%), Positives = 95/179 (53%)
 Frame = +2

Query: 215 SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 394
           S + DLR++T     F +     V+HLAA VGG+  N  +   +F +N  +   +L+   
Sbjct: 49  SNEYDLRERTDIRRAFTQSGADVVVHLAATVGGIGANRENPGRYFYDNAIMGIELLEMAR 108

Query: 395 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574
           +++V K     + C +P+ T  P  E  + +G P  +N  Y  AK+ +   +R Y + Y 
Sbjct: 109 QFDVDKFTILGTICSYPNHTEVPFSEDDLFDGYPEETNAPYGIAKKALLTQSRAYRKQYD 168

Query: 575 CMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFI 751
                ++P N++GP D+F L S+HVIPA+IR+  +A ++GD +  + G      + L++
Sbjct: 169 FNSIYLMPVNLYGPRDDFDLHSAHVIPAIIRKCIEARERGDDSITAWGTGEPTREFLYV 227


>UniRef50_Q9XDD7 Cluster: Bme10; n=1; Brucella melitensis|Rep: Bme10
           - Brucella melitensis
          Length = 246

 Score =  107 bits (256), Expect = 4e-22
 Identities = 54/156 (34%), Positives = 85/156 (54%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           DL  +  TE   + H+P  +I  AA VGG+  N     DF   N++I  N++ A H+  V
Sbjct: 53  DLTRQGPTENFISGHRPDVIIIAAARVGGILANSRFPADFLYNNLAIGMNLIHAAHQIGV 112

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586
           ++++   S+CI+P     P+ E  +  GP   +N  Y+ AK       +     +G  F 
Sbjct: 113 ERLLWLGSSCIYPRDAAQPLTEDALLTGPLEPTNEAYAIAKIAGLKYAQSCARQFGDRFI 172

Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKG 694
           + +P N++GP+DNF   SSHV+PALIRR+ +A  +G
Sbjct: 173 TAMPTNLYGPNDNFDPTSSHVLPALIRRVHEARMRG 208


>UniRef50_Q1VHC4 Cluster: GDP-fucose synthetase chain A; n=1;
           Psychroflexus torquis ATCC 700755|Rep: GDP-fucose
           synthetase chain A - Psychroflexus torquis ATCC 700755
          Length = 311

 Score =  105 bits (251), Expect = 2e-21
 Identities = 57/192 (29%), Positives = 96/192 (50%)
 Frame = +2

Query: 203 IFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNIL 382
           I    K  +L D+ +T     K KP  VI  AA VGG+  NM     F  EN+ I +NI+
Sbjct: 35  IIEDKKKLNLLDQNKTFKFLEKKKPDFVIIAAARVGGIVANMKFKSKFIYENLQIQNNII 94

Query: 383 QACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYN 562
              +   VK +    S+CI+P  +  P+ E  + +GP   +N  Y+ AK     +   Y+
Sbjct: 95  HGSYLAGVKNLFLLGSSCIYPKFSKQPMKEKYLLSGPLEETNDAYAIAKIAGIKMCENYS 154

Query: 563 ESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDS 742
           +++   F S++P N++GP+DN+ L +SH  PAL++++  A  +    F   G      + 
Sbjct: 155 KNFNLNFKSLMPPNLYGPNDNYDLSNSHFYPALLKKIHTAKIQNKKNFLIWGSGKAKREL 214

Query: 743 LFIHXISASCSF 778
           +F+   + +  F
Sbjct: 215 MFVDDFADAVIF 226


>UniRef50_O49213 Cluster: GDP-L-fucose synthase 1; n=181; root|Rep:
           GDP-L-fucose synthase 1 - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 312

 Score =  105 bits (251), Expect = 2e-21
 Identities = 57/184 (30%), Positives = 95/184 (51%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           DL  +   E+ F++ KP +VI  AA VGG+  N  +  DF   N+ I  N++ + +++ V
Sbjct: 42  DLTRQADVESFFSQEKPVYVILAAAKVGGIHANNTYPADFIGVNLQIQTNVIHSAYEHGV 101

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586
           KK++   S+CI+P     PI E+ +       +N  Y+ AK       + Y   +G    
Sbjct: 102 KKLLFLGSSCIYPKFAPQPIPESALLTASLEPTNEWYAIAKIAGIKTCQAYRIQHGWDAI 161

Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXISA 766
           S +P N++GP+DNF  ++SHV+PAL+RR  +A   G       G      + L +  ++ 
Sbjct: 162 SGMPTNLYGPNDNFHPENSHVLPALMRRFHEAKVNGAEEVVVWGTGSPLREFLHVDDLAD 221

Query: 767 SCSF 778
           +C F
Sbjct: 222 ACVF 225


>UniRef50_Q7MV22 Cluster: GDP-fucose synthetase; n=5; Bacteria|Rep:
           GDP-fucose synthetase - Porphyromonas gingivalis
           (Bacteroides gingivalis)
          Length = 357

 Score =  104 bits (249), Expect = 3e-21
 Identities = 52/149 (34%), Positives = 80/149 (53%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           DL D       F K +P +V   AA VGG+  N     DF   N+ I  NI+   +++ V
Sbjct: 41  DLLDAVAVREFFDKEEPQYVFLAAAYVGGIVANNRFRADFIYRNLGIQQNIIGESYRHRV 100

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586
            K++   STCI+P     P+ E  +   P   +N  Y+ AK     +   +N  YG  + 
Sbjct: 101 SKLMFLGSTCIYPRDARQPMREEELLTAPLEYTNEPYAIAKIAGLKMCESFNLQYGTNYI 160

Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRM 673
           +V+P N++GP+DNF L+ SHV+PA+IR++
Sbjct: 161 AVMPTNLYGPNDNFDLERSHVLPAMIRKI 189


>UniRef50_A2BXU6 Cluster: Putative fucose synthetase; n=1;
           Prochlorococcus marinus str. MIT 9515|Rep: Putative
           fucose synthetase - Prochlorococcus marinus (strain MIT
           9515)
          Length = 320

 Score = 99.5 bits (237), Expect = 9e-20
 Identities = 55/156 (35%), Positives = 83/156 (53%)
 Frame = +2

Query: 218 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 397
           KD DLR++         HKP  +I  AA VGG+  N     +F  +N+ I  NI+ A  K
Sbjct: 40  KDLDLRNQIDVNNFIGIHKPDKIILSAAKVGGIQANQNFKCEFLYDNLMIQTNIIDAAAK 99

Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577
            N K +V   S+CI+P ++  PI E  +  G    +N  Y+ AK +   L + Y E Y  
Sbjct: 100 NNTKTLVFIGSSCIYPRESEQPIKENYLLTGLLEPTNEPYALAKIVGLKLAKLYAEKYNI 159

Query: 578 MFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAM 685
                + CN++G +DNF L +SHV+ +L+R+  DA+
Sbjct: 160 QCICPMFCNLYGNNDNFDLINSHVLSSLVRKFVDAV 195


>UniRef50_Q8L2G9 Cluster: Fcl; n=2; Enterobacteriaceae|Rep: Fcl -
           Erwinia chrysanthemi
          Length = 312

 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 52/164 (31%), Positives = 85/164 (51%), Gaps = 1/164 (0%)
 Frame = +2

Query: 260 FAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCI 439
           F +H+P +V HLA++V GL  N+ + L     N  IN N++ ACHK+NVKK+    +   
Sbjct: 52  FNQHQPDYVFHLASLVFGLKGNLDNQLKSISNNTIINQNVILACHKFNVKKIFFAGTVAS 111

Query: 440 FP-DKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGP 616
           +P      P+DE  +  G PH   +GY+ +KR      +  N+ +   +   +  N+FG 
Sbjct: 112 YPFPYVQLPLDEGDLMLGEPHGGEYGYAMSKRHALAYLKILNQYHNVDYCYALFTNLFGA 171

Query: 617 HDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLF 748
           +D F   + HVIP+LI +  +++ +GD      G      D L+
Sbjct: 172 NDKFDPINGHVIPSLIDKTYNSLLRGDNQLTVWGRPETTRDFLY 215


>UniRef50_O84974 Cluster: O-antigen biosynthesis protein; n=5;
           Helicobacter|Rep: O-antigen biosynthesis protein -
           Helicobacter pylori (Campylobacter pylori)
          Length = 310

 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 51/164 (31%), Positives = 82/164 (50%)
 Frame = +2

Query: 230 LRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVK 409
           L DK   +A   ++KPT +IH A  VGG+  NM     +  EN+ +   +  +     VK
Sbjct: 41  LLDKDNVQAYLKEYKPTGIIHCAGRVGGIVANMNDLSTYMVENLLMGLYLFSSALDLGVK 100

Query: 410 KVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTS 589
           K ++  S+C +P     P+ E+ + NG    +N GY+ AK  +       +   G  + +
Sbjct: 101 KAINLASSCAYPKYAPNPLKESDLLNGSLEPTNEGYALAKLSVMKYCEYVSTEKGGFYKT 160

Query: 590 VIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGE 721
           ++PCN++G  D F  K +H+IP LI RM  A  K +  F   G+
Sbjct: 161 LVPCNLYGEFDKFEEKIAHMIPGLIARMHTAKLKNEKNFAMWGD 204


>UniRef50_A1B1K8 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Alphaproteobacteria|Rep: NAD-dependent
           epimerase/dehydratase - Paracoccus denitrificans (strain
           Pd 1222)
          Length = 307

 Score = 97.9 bits (233), Expect = 3e-19
 Identities = 52/169 (30%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           DL D        A+ +P  V+H A  VGG+  NMA  + +   N  I  N++ AC    +
Sbjct: 37  DLCDARALRDWLARQRPDAVVHAAGAVGGIQANMAEPVRYLAGNALIGLNLITACRDAGI 96

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRM-IDVLNRGYNESYGCMF 583
             +++  S+C++P      + E  +  G    SN GY+ AK M + +++    E     +
Sbjct: 97  PVLINLSSSCVYPRDLGRDLSEEQILTGALEPSNEGYALAKIMAMRLVDYTCREDRSLQW 156

Query: 584 TSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPT--FXSDGEA 724
            ++IPCN++GPHD F  + SH++PA+I ++  A  +G  T     DG A
Sbjct: 157 RTLIPCNLYGPHDKFDPRRSHLLPAIIHKIHRARVEGHETVEIWGDGTA 205


>UniRef50_A5GHX4 Cluster: GDP-L fucose synthetase; n=25;
           Bacteria|Rep: GDP-L fucose synthetase - Synechococcus
           sp. (strain WH7803)
          Length = 343

 Score = 96.7 bits (230), Expect = 6e-19
 Identities = 57/191 (29%), Positives = 91/191 (47%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           DL D +         +P  V+  AA VGG+  N +   DF  +N+ I   +++A  +  V
Sbjct: 53  DLLDDSAVRDWMEAQRPDVVVLAAATVGGIEANRSRPADFLLQNLRIETQVIEAAWRCGV 112

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586
           ++++   S+CI+P     PI E  +  G    +N  Y+ AK     L       +G    
Sbjct: 113 RRLLFLGSSCIYPKFADQPIREEALLTGALEPTNAWYAIAKIAGIKLAEALRLQHGFDAI 172

Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXISA 766
           S++P N++GP DN+    SHV+PALIRR  +A Q+GD +    G      + L    +  
Sbjct: 173 SLMPTNLYGPGDNYHPTGSHVLPALIRRFHEAKQRGDASVTCWGTGTPLREFLHADDLGE 232

Query: 767 SCSFGVLXNST 799
           +C F +   ST
Sbjct: 233 ACVFALEHWST 243


>UniRef50_Q9AQ09 Cluster: Putative nodulation NAD-dependent
           nucleotide sugar epimerase; n=1; Bradyrhizobium sp.
           WM9|Rep: Putative nodulation NAD-dependent nucleotide
           sugar epimerase - Bradyrhizobium sp. (strain WM9)
          Length = 289

 Score = 92.3 bits (219), Expect = 1e-17
 Identities = 55/185 (29%), Positives = 92/185 (49%)
 Frame = +2

Query: 218 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 397
           ++ DL ++      FAK +P  +   AA VGG+  N     +F  +N++I  N++QA H+
Sbjct: 23  REVDLCNQAAVFDWFAKVRPQVIFLAAAKVGGIVANATLRAEFIYDNIAIAANVIQAAHQ 82

Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577
              +K++   S+CI+P     P+ E  V  GP            +M++     Y   YG 
Sbjct: 83  NGAEKLMFLGSSCIYPKLAAQPLREDSVLTGP---------LEIKMVE----AYRSQYGS 129

Query: 578 MFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHX 757
            F SV+P N++GP DN+  + SHV+ ALIRR  +A   G  +    G      + L++  
Sbjct: 130 DFISVMPTNLYGPGDNYHPEYSHVVAALIRRFHEAKVSGARSVVVWGTGTPRREFLYVDD 189

Query: 758 ISASC 772
           ++ +C
Sbjct: 190 MADAC 194


>UniRef50_Q8VQ41 Cluster: WbdJ; n=13; Bacteria|Rep: WbdJ -
           Escherichia coli
          Length = 307

 Score = 91.9 bits (218), Expect = 2e-17
 Identities = 50/157 (31%), Positives = 79/157 (50%), Gaps = 1/157 (0%)
 Frame = +2

Query: 215 SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 394
           S + +L D          H P  +IH A +VGG+  N+   +DF   N+ +  NI+    
Sbjct: 32  SSELNLLDNKAVHDYITCHSPDLIIHAAGLVGGIQANIKRPVDFLVSNLKMGVNIVNEAK 91

Query: 395 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGY-NESY 571
              VK  ++  S+C++P      I E  +  G    +N GY+ AK  +  L      ES 
Sbjct: 92  NCGVKNFINLGSSCMYPKGIDTAISEDALLTGKLEHTNEGYALAKITVAKLCEYITKESE 151

Query: 572 GCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDA 682
           G  + ++IPCN++G +D F   SSH+IPA+I R+ +A
Sbjct: 152 GYHYKTIIPCNLYGKYDKFDEHSSHMIPAVINRIHNA 188


>UniRef50_P33217 Cluster: Nodulation protein nolK; n=2;
           Alphaproteobacteria|Rep: Nodulation protein nolK -
           Azorhizobium caulinodans
          Length = 312

 Score = 89.8 bits (213), Expect = 7e-17
 Identities = 48/180 (26%), Positives = 92/180 (51%)
 Frame = +2

Query: 215 SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 394
           S D DLR+    E    +  P  V+H A +VGG+  N+A  + F  +N ++  N++ +  
Sbjct: 36  SVDLDLRNAEAVEQYIRRQLPDVVVHAAGVVGGIHANIADPIHFLADNAAMALNVVMSSF 95

Query: 395 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574
           +  V  +++  S+C++P     P+ E  +  GP   +N GY+ AK +   +    ++   
Sbjct: 96  RSEVVTLINLSSSCMYPACIEGPLKECDILRGPFEVTNEGYALAKTVGLKICEYIDKLPN 155

Query: 575 CMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIH 754
             + ++I CN++G  DNF  + SH++PA+I ++  A Q G  +    G+     + +F +
Sbjct: 156 FNYKTLIACNLYGVGDNFDPRRSHLLPAIIEKIHKASQCGSESVSIWGDGTARREFMFAY 215


>UniRef50_Q2BI22 Cluster: DTDP-glucose dehydratase; n=1;
           Neptuniibacter caesariensis|Rep: DTDP-glucose
           dehydratase - Neptuniibacter caesariensis
          Length = 312

 Score = 87.4 bits (207), Expect = 4e-16
 Identities = 50/160 (31%), Positives = 81/160 (50%)
 Frame = +2

Query: 215 SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 394
           S + DL    Q E          + HLAA VGG+ +  AH  + F  N+ +N  +L A  
Sbjct: 37  SSECDLLCYEQIEVSLQSESFDLIFHLAADVGGIGYMQAHGAEVFENNLLMNTQLLHAAR 96

Query: 395 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574
           +  V K+V+  S   +P +   P  E+ + +G P     GY+YAKR + V +    + +G
Sbjct: 97  RNGVGKLVNIASINCYPAEAEAPYLESSLFDGQPALPVLGYAYAKRAMLVHSELARQQFG 156

Query: 575 CMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKG 694
               ++I  +V+GP ++FSL ++ V+PA + R  DA   G
Sbjct: 157 FNSINLILDSVYGPGESFSLDTARVLPANVARFVDAAHSG 196


>UniRef50_Q67WR5 Cluster: Putative GDP-L-fucose synthase 2; n=4;
           Oryza sativa|Rep: Putative GDP-L-fucose synthase 2 -
           Oryza sativa subsp. japonica (Rice)
          Length = 347

 Score = 85.0 bits (201), Expect = 2e-15
 Identities = 51/157 (32%), Positives = 78/157 (49%), Gaps = 1/157 (0%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY-N 403
           DL  +   EA FA   P +VI  AA VGG+  + A   ++  EN+ I  N++ A  +  +
Sbjct: 71  DLACQAAVEAFFAAELPRYVILAAAKVGGVHASSAAPAEYLTENLRITVNVVDAARRCGS 130

Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583
           V+K++   S+ I+P     P  E+ +  GPP   +  Y+  K     + +     YG   
Sbjct: 131 VRKLLVLASSTIYPADAPQPTPESALLTGPPAEGSEWYAIPKIAGIKMCQAVRAEYGLDA 190

Query: 584 TSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKG 694
            +  P N++GP   F  + SHVIPALIRR   A  +G
Sbjct: 191 IAAAPNNLYGPRHPFPPEHSHVIPALIRRFHRAKLEG 227


>UniRef50_A0R4U4 Cluster: NAD dependent epimerase/dehydratase family
           protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep:
           NAD dependent epimerase/dehydratase family protein -
           Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 323

 Score = 73.7 bits (173), Expect = 5e-12
 Identities = 49/156 (31%), Positives = 81/156 (51%), Gaps = 5/156 (3%)
 Frame = +2

Query: 218 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGL--FHNMAHNLDFFRENMSINDNILQAC 391
           + GDLR   +  A  A    THVIHLAA+VGG+  FH + H L     N  + +++  A 
Sbjct: 48  RTGDLRSADEARA--AVDGCTHVIHLAAIVGGIANFHRLPHTL--LEMNTGLYNSVFSAA 103

Query: 392 HKYNVKKVVSCLSTCIFPDKTTYP-IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNES 568
            +  V+++V   S+ +F   T +P  +E ++   PP S+   Y ++K   ++  R  +E 
Sbjct: 104 LREGVERLVYVSSSMVFEQATQFPTTEEHLLDCRPPRSA---YGFSKLTGEIYCRAVHEE 160

Query: 569 YGCMFTSVIPCNVFGPHD--NFSLKSSHVIPALIRR 670
           +G  FT   P N +GP +  +     +H +P LIR+
Sbjct: 161 HGLPFTICRPFNAYGPGELPDTEPGIAHAVPDLIRK 196


>UniRef50_Q30CR4 Cluster: LipDig4; n=3; Streptomyces|Rep: LipDig4 -
           Streptomyces aureofaciens
          Length = 355

 Score = 61.3 bits (142), Expect = 3e-08
 Identities = 42/151 (27%), Positives = 64/151 (42%), Gaps = 2/151 (1%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTH--VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400
           DL D T   A      P    ++H AA+ G       +       NM +  N+L+A    
Sbjct: 85  DLLDDTALSAALRSVTPRVDLIVHCAALYGNADFKKRNPALILDANMRMASNVLRAARAC 144

Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580
           +V  VV   S  I+ +    P  E   +   P  +  GY+ AK   ++L   +   YG  
Sbjct: 145 DVGDVVMMGSAEIYSELAPSPAREDDDYRRYPVPTQNGYALAKIYTEMLAEFFRTQYGMR 204

Query: 581 FTSVIPCNVFGPHDNFSLKSSHVIPALIRRM 673
                P NV+GP D+F    S V+P+L+ R+
Sbjct: 205 IFVPRPTNVYGPRDDFDASVSRVVPSLMNRI 235


>UniRef50_Q1J353 Cluster: GDP-L-fucose synthase; n=1; Deinococcus
           geothermalis DSM 11300|Rep: GDP-L-fucose synthase -
           Deinococcus geothermalis (strain DSM 11300)
          Length = 316

 Score = 61.3 bits (142), Expect = 3e-08
 Identities = 42/188 (22%), Positives = 79/188 (42%)
 Frame = +2

Query: 215 SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 394
           +++ DLR+K Q  A F K  P +V   +  V G   +  +   +  +N+ +  N + A +
Sbjct: 39  ARELDLREKDQVHAFFEKELPDYVFVSSVKVEGPVRDAIYPAQWLHDNLLVMANTIHAAY 98

Query: 395 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574
            Y+V+K+V    +  + D    P   + +       +    +   +    L   Y   YG
Sbjct: 99  LYDVEKLVCIDCSSTYADLGALPRTMSYLQAELIEETQRVCTVVSQTTTELCDSYRRQYG 158

Query: 575 CMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIH 754
           C F S +  +++GP    S + S V+ AL+  M  A + G        +     D L+  
Sbjct: 159 CDFVSAVFSSLYGPPLGGSGQRSSVVLALLHDMQRAKETGQAAVRWPSDDRWCRDLLYAD 218

Query: 755 XISASCSF 778
            ++ +C F
Sbjct: 219 DMADACLF 226


>UniRef50_Q18EM2 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=1; Haloquadratum walsbyi DSM 16790|Rep:
           Nucleoside-diphosphate-sugar epimerase - Haloquadratum
           walsbyi (strain DSM 16790)
          Length = 345

 Score = 59.7 bits (138), Expect = 8e-08
 Identities = 42/149 (28%), Positives = 71/149 (47%), Gaps = 4/149 (2%)
 Frame = +2

Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDK---- 451
           V HLAA VGG+ +    N+     ++ +N ++L+A    +V + +   S C++  +    
Sbjct: 85  VYHLAASVGGIHYIQRENVHGLTPSVLMNQHMLEAARIQDVDRFLFASSACVYRQQHDEL 144

Query: 452 TTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFS 631
             +  D+ +  N  PHS+   Y +AK + +V    Y+        +V   N +GP +N  
Sbjct: 145 NRFSEDQAIPAN--PHST---YGWAKVLGEVACDAYHTDTTVDTGAVRIFNAYGPRENLD 199

Query: 632 LKSSHVIPALIRRMDDAMQKGDPTFXSDG 718
             SSHVIPAL R++ +A          DG
Sbjct: 200 PDSSHVIPALCRKVIEADDGDSIELFGDG 228


>UniRef50_A6GLY7 Cluster: Putative uncharacterized protein; n=1;
           Limnobacter sp. MED105|Rep: Putative uncharacterized
           protein - Limnobacter sp. MED105
          Length = 294

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 53/192 (27%), Positives = 83/192 (43%), Gaps = 2/192 (1%)
 Frame = +2

Query: 149 VIERDRQKRNSDYDSETWIFSGS--KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFH 322
           VI  D        + E W+   +   +GD+RD++  E L A+       HLAA+V  +  
Sbjct: 12  VIVLDNLSSGRRENIENWLGPNTCLVEGDIRDQSLVENLLAE--TAGAFHLAALVS-VPQ 68

Query: 323 NMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHS 502
           ++    + F  N+    N+L+A  K   KK+V   S  ++ ++ +YP+ ETM   G P S
Sbjct: 69  SIERPTESFSINLEGTLNLLEASRKQGNKKIVFASSAAVYGNRHSYPVSETMA--GQPIS 126

Query: 503 SNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDA 682
               Y   K M +     +   Y      +   NV+GP  + S   S VI   I R+   
Sbjct: 127 P---YGLHKLMCEQHAELFANLYNVNSVGMRFFNVYGPRQDPSSPYSGVISIFIDRLRRG 183

Query: 683 MQKGDPTFXSDG 718
           +    PT   DG
Sbjct: 184 LA---PTIYGDG 192


>UniRef50_Q5SKQ2 Cluster: UDP-glucose 4-epimerase; n=4; Thermus|Rep:
           UDP-glucose 4-epimerase - Thermus thermophilus (strain
           HB8 / ATCC 27634 / DSM 579)
          Length = 311

 Score = 56.4 bits (130), Expect = 8e-07
 Identities = 42/134 (31%), Positives = 62/134 (46%), Gaps = 1/134 (0%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           DLRDK   E  F + +PTHV H AA            LD F  N+    N+L+AC +Y V
Sbjct: 51  DLRDKEGVERAFREFRPTHVSHQAAQASVKVSVEDPVLD-FEVNLLGGLNLLEACRQYGV 109

Query: 407 KKVV-SCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583
           +K+V +     I+ +    P  E      PP   +  Y+ +K   +     Y +SYG  +
Sbjct: 110 EKLVFASTGGAIYGE---VPEGERAEETWPPRPKS-PYAASKAAFEHYLSVYGQSYGLKW 165

Query: 584 TSVIPCNVFGPHDN 625
            S+   NV+GP  +
Sbjct: 166 VSLRYGNVYGPRQD 179


>UniRef50_Q83DA9 Cluster: NAD dependent epimerase/dehydratase family
           protein; n=9; Bacteria|Rep: NAD dependent
           epimerase/dehydratase family protein - Coxiella burnetii
          Length = 330

 Score = 54.0 bits (124), Expect = 4e-06
 Identities = 46/163 (28%), Positives = 73/163 (44%), Gaps = 2/163 (1%)
 Frame = +2

Query: 236 DKTQTEALFAKHKPTH-VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKK 412
           D  QT+ L    K    V H AA+   L     +    F+ N+    N+L+ C    VK+
Sbjct: 64  DINQTDILNTALKGVDGVFHFAAL--WLLQCYEYPRSAFQTNIQGTFNVLETCVAQGVKR 121

Query: 413 VVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSV 592
           +V   S  ++ D    P+ E   H   P +S   Y   K   + +   Y+  YG  F  +
Sbjct: 122 LVFSSSASVYGDALEEPMTEA--H---PFNSRTFYGATKIAGEAMATAYHHRYGLPFVGL 176

Query: 593 IPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDP-TFXSDG 718
              NV+GP  ++  + +++  A+I +M DA+ KG P T   DG
Sbjct: 177 RYMNVYGPRQDY--RGAYI--AVIMKMLDALDKGQPMTLYGDG 215


>UniRef50_Q1GN57 Cluster: NAD-dependent epimerase/dehydratase; n=24;
           Alphaproteobacteria|Rep: NAD-dependent
           epimerase/dehydratase - Silicibacter sp. (strain TM1040)
          Length = 333

 Score = 53.6 bits (123), Expect = 6e-06
 Identities = 36/131 (27%), Positives = 57/131 (43%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           G L D  +   L A HKP  VIHLAA   G+ H++    D+   N+     +L+A   + 
Sbjct: 61  GKLEDPGRLMGLLADHKPNAVIHLAAQ-AGVRHSIDAPRDYLEANLIGTFEVLEAARAHP 119

Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583
            + ++   ++  +   T  P DE   H    H  +F Y+  K+  + +   Y   YG   
Sbjct: 120 PEHIMIASTSSAYGANTNIPFDE---HQKADHQMSF-YAATKKAGETMAHSYAHLYGLPT 175

Query: 584 TSVIPCNVFGP 616
           T      V+GP
Sbjct: 176 TMFRFFTVYGP 186


>UniRef50_Q55412 Cluster: Slr0583 protein; n=3; Chroococcales|Rep:
           Slr0583 protein - Synechocystis sp. (strain PCC 6803)
          Length = 310

 Score = 53.2 bits (122), Expect = 7e-06
 Identities = 42/165 (25%), Positives = 72/165 (43%), Gaps = 4/165 (2%)
 Frame = +2

Query: 236 DKTQTEAL--FAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVK 409
           D TQ ++L  F K     + HLAA        ++H  + +  N  +N N+L   H    +
Sbjct: 36  DLTQPDSLHQFTKGSFDQIYHLAAWTQAGDFCLSHPGEQWLINQKLNTNVLDWWHSQQPQ 95

Query: 410 -KVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586
            K++   ++C +      P++E     G P  S F Y+  KRM+        + YG  + 
Sbjct: 96  AKLIFMGTSCAYDPNL--PLEEEYYLTGLPIDSLFTYAMTKRMLYAGALALQKQYGLKYL 153

Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDP-TFXSDG 718
            ++P  ++GP  +   +  H I  LIR++      G+  T   DG
Sbjct: 154 CLVPSTLYGPGYHTDGRQMHFIFDLIRKIIRGKLYGETVTLWGDG 198


>UniRef50_A5GEL7 Cluster: NAD-dependent epimerase/dehydratase
           precursor; n=1; Geobacter uraniumreducens Rf4|Rep:
           NAD-dependent epimerase/dehydratase precursor -
           Geobacter uraniumreducens Rf4
          Length = 336

 Score = 52.8 bits (121), Expect = 1e-05
 Identities = 41/166 (24%), Positives = 79/166 (47%), Gaps = 6/166 (3%)
 Frame = +2

Query: 281 HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFP----- 445
           +V HLA +VGG+    ++ L  FR+N++I+ N++ AC    +   +   + C +P     
Sbjct: 82  YVFHLADIVGGIQFAFSNELFIFRQNITIDTNVVSACITNGIGNYIYVGTACSYPKYLQM 141

Query: 446 DKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPC-NVFGPHD 622
           +K    + E  V+   P SS +G+S   +++           G +   ++   NV+GP  
Sbjct: 142 NKGITALKEDQVYPAEPESS-YGWS---KLMGEYGADLALKSGRINVGILRFHNVYGPGV 197

Query: 623 NFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXI 760
            F   ++ V+P+L+R+   A++     F   G    + D ++I  I
Sbjct: 198 EFEGNTAQVLPSLMRK---AIRFPQEDFIVWGSGNQYRDFVYIDDI 240


>UniRef50_Q2NIA3 Cluster: Putative UDP-glucose 4-epimerase; n=1;
           Methanosphaera stadtmanae DSM 3091|Rep: Putative
           UDP-glucose 4-epimerase - Methanosphaera stadtmanae
           (strain DSM 3091)
          Length = 315

 Score = 52.8 bits (121), Expect = 1e-05
 Identities = 41/171 (23%), Positives = 78/171 (45%)
 Frame = +2

Query: 281 HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTY 460
           ++ H AA++  +F ++       + N+  + N+LQA ++ N+KKV+S  S  ++ +    
Sbjct: 74  YLFHEAALIS-VFESIEQPKATNKTNIDGSFNVLQAAYESNIKKVISASSAAVYGETEVL 132

Query: 461 PIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKS 640
           P  ET+     P      Y+ +K ++++ +  + ++Y      +   NVFGP        
Sbjct: 133 PNVETL-----PLQPLSPYAVSKALLELYSYTFTQTYHLPTACLRYFNVFGPRQKADSPY 187

Query: 641 SHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXISASCSFGVLXN 793
           S VIP  I  +   +    P    DGE     D +++  I A  ++ V  N
Sbjct: 188 SGVIPKFISAL---LNNETPVIYGDGEQTR--DFIYVKNI-AKANYEVAIN 232


>UniRef50_Q9ZHQ3 Cluster: 4-ketoreductase; n=2; Actinomycetales|Rep:
           4-ketoreductase - Streptomyces fradiae
          Length = 336

 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 37/151 (24%), Positives = 62/151 (41%), Gaps = 3/151 (1%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTH--VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400
           DL D+  T   F +  P    VIH A + G   +   H+      N+    ++L      
Sbjct: 65  DLCDEAATRRAFQEWAPGADVVIHCAGLDGNAQYKRDHSASVLDANVRGTAHVLNTARDT 124

Query: 401 NVKKVVSCLSTCIFPDKTTYPI-DETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577
               VV   ST ++      P  ++  +    PH+ N GY  +K   +++   +   +G 
Sbjct: 125 GAGAVVLLSSTEVYCAPRDSPAREDEEIRRYVPHAGN-GYVLSKIFCEIMAELHGAEFGS 183

Query: 578 MFTSVIPCNVFGPHDNFSLKSSHVIPALIRR 670
               V P NV+GP D      + VIP+++ R
Sbjct: 184 RIFRVRPGNVYGPRDGNGGTRTRVIPSMVAR 214


>UniRef50_Q9K7I2 Cluster: UDP-glucose 4-epimerase; n=17; cellular
           organisms|Rep: UDP-glucose 4-epimerase - Bacillus
           halodurans
          Length = 308

 Score = 50.0 bits (114), Expect = 7e-05
 Identities = 44/176 (25%), Positives = 80/176 (45%), Gaps = 2/176 (1%)
 Frame = +2

Query: 242 TQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSI--NDNILQACHKYNVKKV 415
           ++ + +F+K KP +VIH AA V       + NL  +    +I    N+L  C +Y V KV
Sbjct: 58  SELKDIFSKEKPNYVIHHAAQVD---VTKSINLPTYDAETNIIGTINLLSCCCQYEVDKV 114

Query: 416 VSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVI 595
           +   S  ++ D      D ++  + P    +F Y  +K + ++  R +++ YG  +T   
Sbjct: 115 IYASSCAVYGDTG----DSSITEDFPIQPISF-YGISKSVPEMYIRQFHDLYGLKYTIFR 169

Query: 596 PCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXIS 763
             NV+GP    S     VI     +   A+++  P    +GE     D +++  I+
Sbjct: 170 YANVYGPRQT-SKGEGGVISIFTTK---ALKREQPIIYGNGEQTR--DFIYVEDIA 219


>UniRef50_A5GIA6 Cluster: NAD dependent epimerase/dehydratase; n=19;
           Bacteria|Rep: NAD dependent epimerase/dehydratase -
           Synechococcus sp. (strain WH7803)
          Length = 343

 Score = 49.6 bits (113), Expect = 9e-05
 Identities = 31/122 (25%), Positives = 59/122 (48%)
 Frame = +2

Query: 251 EALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLS 430
           + LFA+ KP  V++LAA   G+ +++ +   + + N+    NIL+ C  + V+ +V   S
Sbjct: 77  QELFAREKPRVVVNLAAQ-AGVRYSLENPAAYIQSNLVGFGNILEGCRHHGVENLVYASS 135

Query: 431 TCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVF 610
           + ++      P  E    N P       Y+ +K+  +++   Y+  YG   T +    V+
Sbjct: 136 SSVYGGNRNLPFHEQQPVNHPVSL----YAASKKANELMAHTYSHLYGLPATGLRFFTVY 191

Query: 611 GP 616
           GP
Sbjct: 192 GP 193


>UniRef50_Q12VP0 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Methanococcoides burtonii DSM 6242|Rep: NAD-dependent
           epimerase/dehydratase - Methanococcoides burtonii
           (strain DSM 6242)
          Length = 303

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 43/150 (28%), Positives = 69/150 (46%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           D  D T  E +    K   ++HLA M   +  +  H  D +  N     N+L+ C   +V
Sbjct: 45  DSIDITNWEQVKTIPKRDVLVHLAGMTN-IPESFNHPRDVYTINTFGTLNMLEWCRLNDV 103

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586
           K+ +   ST ++ +    P+DE   H   P   N  YS +K + + L   Y   YG    
Sbjct: 104 KRFIYA-STFVYGNPQYTPVDEK--H---PTLPNNPYSQSKLIGEELCNAYCRDYGIDVI 157

Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMD 676
           S+   NV+GPH     K  ++IP +IR+++
Sbjct: 158 SLRLFNVYGPHQ----KGDYLIPHIIRQLE 183


>UniRef50_Q8DJM2 Cluster: Nucleotide sugar epimerase; n=61; cellular
           organisms|Rep: Nucleotide sugar epimerase -
           Synechococcus elongatus (Thermosynechococcus elongatus)
          Length = 338

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 34/130 (26%), Positives = 60/130 (46%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           DL D+     LFA   P  VIHLAA   G+ +++ +   +   N+    +IL+AC  + V
Sbjct: 64  DLVDRLGVNQLFADFSPQKVIHLAAQ-AGVRYSLENPFAYIDSNIVGFLHILEACRHHRV 122

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586
           + +V   S+ ++      P     VH+   H  +  Y+  K+  +++   Y+  Y    T
Sbjct: 123 EHLVYASSSSVYGANKKLPFS---VHDNVDHPLSL-YAATKKANELMAHTYSHLYNIPTT 178

Query: 587 SVIPCNVFGP 616
            +    V+GP
Sbjct: 179 GLRFFTVYGP 188


>UniRef50_Q5KWG9 Cluster: Nucleotide sugar epimerase; n=1;
           Geobacillus kaustophilus|Rep: Nucleotide sugar epimerase
           - Geobacillus kaustophilus
          Length = 314

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 37/130 (28%), Positives = 61/130 (46%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           DL D   T+  F++ +P  V HLAA+ G + +++AH L +   ++    N+L A  +  V
Sbjct: 60  DLLDGEATKRWFSQFRPDVVYHLAALPG-VPYSLAHPLAYIDYDIKATVNVLAAAGEAGV 118

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586
             V+   S+ ++ D+   P+ E M  +G   S    Y+ AK   +     Y   YG   T
Sbjct: 119 AHVLFASSSSVYGDRGNVPLREEMA-DGRVVSP---YAAAKYGAESFCHAYAHLYGYQMT 174

Query: 587 SVIPCNVFGP 616
                 V+GP
Sbjct: 175 IFRYFTVYGP 184


>UniRef50_O06485 Cluster: YfnG; n=3; Bacteria|Rep: YfnG - Bacillus
           subtilis
          Length = 301

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 50/195 (25%), Positives = 84/195 (43%), Gaps = 5/195 (2%)
 Frame = +2

Query: 146 TVIERDRQKRNSDYDSETWIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAM-VGGLFH 322
           T + RD   +++ Y  E         G L D    E    +++   V HLAA  + G+ +
Sbjct: 13  TGLVRDHVPQSNLYQGEHIKKMNIVRGSLEDLAVIERALGEYEIDTVFHLAAQAIVGVAN 72

Query: 323 NMAHNLDFFRENMSINDNILQACHKYN-VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPH 499
              + +  F  N+    NIL+AC K+  +K+V+   S   + D+   P DE M     P 
Sbjct: 73  R--NPISTFEANILGTWNILEACRKHPLIKRVIVASSDKAYGDQENLPYDENM-----PL 125

Query: 500 SSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRM-- 673
                Y  +K   D+++  Y  +YG         N++G  D   L  + +IP  I+ +  
Sbjct: 126 QGKHPYDVSKSCADLISHTYFHTYGLPVCITRCGNLYGGGD---LNFNRIIPQTIQLVLN 182

Query: 674 DDAMQ-KGDPTFXSD 715
            +A + + D TF  D
Sbjct: 183 GEAPEIRSDGTFVRD 197


>UniRef50_Q5KUQ5 Cluster: UDP-glucose 4-epimerase; n=5;
           Bacteria|Rep: UDP-glucose 4-epimerase - Geobacillus
           kaustophilus
          Length = 323

 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 35/143 (24%), Positives = 66/143 (46%), Gaps = 2/143 (1%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAA--MVGGLFHNMAHNLDFFRENMSINDNILQACHK 397
           GDL +K   E +F K+    V+H AA  +VG    ++ + L +++ N++    +L+   K
Sbjct: 48  GDLGNKADLEPIFGKYPIQAVMHFAANSLVG---ESVVNPLKYYQNNVAATLTLLETMLK 104

Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577
           YNVK  +   +   +      P  E +  + P +  N  Y  +K MI+ +   +  +YG 
Sbjct: 105 YNVKNFIFSSTAATY----GIPNVELITEDCPTNPIN-PYGRSKLMIEQILADFASAYGL 159

Query: 578 MFTSVIPCNVFGPHDNFSLKSSH 646
            +  +   N  G H++  +   H
Sbjct: 160 NYVVLRYFNAAGAHESGEIGEDH 182


>UniRef50_A5WE41 Cluster: NAD-dependent epimerase/dehydratase; n=5;
           Bacteria|Rep: NAD-dependent epimerase/dehydratase -
           Psychrobacter sp. PRwf-1
          Length = 357

 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 34/130 (26%), Positives = 63/130 (48%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           D+ D+   E+LFA+H+   V HLAA   G+ +++ +   +   N+    NIL+ C ++NV
Sbjct: 79  DIADRAAMESLFAEHQFDAVCHLAAQ-AGVRYSIENPHVYVETNVVGFLNILEGCRQHNV 137

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586
             +    S+ ++    + P  +T  H   P S    Y+  K+  +++   Y   +G   T
Sbjct: 138 DNLCFASSSSVYGLNQSQPF-KTSDHTDHPVSL---YAATKKSNEMMAHTYAHLFGIRCT 193

Query: 587 SVIPCNVFGP 616
            +    V+GP
Sbjct: 194 GLRFFTVYGP 203


>UniRef50_A0L5P6 Cluster: UDP-glucose 4-epimerase; n=4;
           Bacteria|Rep: UDP-glucose 4-epimerase - Magnetococcus
           sp. (strain MC-1)
          Length = 337

 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 44/162 (27%), Positives = 71/162 (43%), Gaps = 3/162 (1%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLA--AMVGGLFHNMAHNLDFFRENMSINDNILQACHK 397
           G L D  +   LFA+++P  VIHLA  A VG    +M     ++R N+     +L+   +
Sbjct: 50  GGLDDGAKLAGLFAQYQPQAVIHLAGRAYVG---ESMTDPALYYRNNVQAALVLLECMRQ 106

Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577
           Y  K ++   S   + +    PI E M      H  N  Y  +K M + + + Y + YG 
Sbjct: 107 YGCKNIIFSSSCATYGEHRQMPITEAM----SQHPIN-PYGRSKLMFEWMLQDY-QVYGL 160

Query: 578 MFTSVIPCNVFGPHDNFSLKSSH-VIPALIRRMDDAMQKGDP 700
              ++   N  G      +   H   P +I R+ +A +KG P
Sbjct: 161 QSVALRYFNASGADLEGEIGEQHQPEPHIIPRLLEAARKGSP 202


>UniRef50_A1SL10 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Actinomycetales|Rep: NAD-dependent epimerase/dehydratase
           - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 346

 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 49/188 (26%), Positives = 80/188 (42%), Gaps = 17/188 (9%)
 Frame = +2

Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGL--FHNMAHNLDFFRENM--SINDNILQA 388
           +GD+RD      L A     H++  AA++GG+  FH   ++L    E +  +  D  ++A
Sbjct: 59  EGDVRDLELMADLVADCD--HLVAGAALIGGISYFHTYPYDLLATNERIIAATCDTAIRA 116

Query: 389 CHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNES 568
                ++KV    S+ +F     +P  E      PP  S++G+   K  ++   R   + 
Sbjct: 117 MPAGRLRKVTYLSSSMVFESTDRWPSKEGDERVIPPPLSSYGFQ--KLAVEYFARAAWDQ 174

Query: 569 YGCMFTSVIPCNVFG------------PHDNFSLKSSHVIPALIRRMDDAMQKGDPT-FX 709
           Y   +T V P N  G            P  N  L  SHV+P LI+++   ++  DP    
Sbjct: 175 YRVPYTIVRPFNCVGVGEGRALGDVEIPSGNIKLAMSHVVPDLIQKV---LRGQDPVHVL 231

Query: 710 SDGEAXNH 733
            DG    H
Sbjct: 232 GDGSQVRH 239


>UniRef50_A2SRX5 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Methanocorpusculum labreanum Z|Rep: NAD-dependent
           epimerase/dehydratase - Methanocorpusculum labreanum
           (strain ATCC 43576 / DSM 4855 / Z)
          Length = 307

 Score = 46.8 bits (106), Expect = 6e-04
 Identities = 38/150 (25%), Positives = 67/150 (44%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           G + D+     +   H    + HLAA V  +  ++   L     N +   NIL A  ++ 
Sbjct: 50  GSVTDRPLLAEICKTHSFEGIFHLAA-VASVQKSIEDPLLVHEVNATGTLNILNAAKEHG 108

Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583
           ++KVV   S   + D   +P  E M+    P S    Y+ +K   ++  R + + +G   
Sbjct: 109 IRKVVLSASAAAYGDNPVFPKREDMLPE--PLSP---YAVSKITAEMYCRNFADLFGVET 163

Query: 584 TSVIPCNVFGPHDNFSLKSSHVIPALIRRM 673
           T++   NVFGP  + + + + VIP    R+
Sbjct: 164 TALRYFNVFGPRQDPNAEYAAVIPKFTERI 193


>UniRef50_Q9FB21 Cluster: Sugar epimerase BlmG; n=1; Streptomyces
           verticillus|Rep: Sugar epimerase BlmG - Streptomyces
           verticillus
          Length = 325

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 32/132 (24%), Positives = 53/132 (40%), Gaps = 2/132 (1%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           DLRD  Q     A      V  LAA +GG+        +   +N+ I+ + ++AC    V
Sbjct: 50  DLRDAAQAARAVAG--ADSVFALAANMGGIGWTHTAPAEILHDNLLISTHTIEACRAAGV 107

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGP--PHSSNFGYSYAKRMIDVLNRGYNESYGCM 580
           +  V   S C++P       D   +   P  P   +  Y + K   ++L   Y  S+G  
Sbjct: 108 RTTVYTSSACVYPASLQREPDAAPLAEDPVFPAEPDMEYGWEKLTTEILCGAYRRSHGMD 167

Query: 581 FTSVIPCNVFGP 616
             +     ++GP
Sbjct: 168 IKTARLHAIYGP 179


>UniRef50_A5UK04 Cluster: UDP-glucose 4-epimerase; n=2;
           Euryarchaeota|Rep: UDP-glucose 4-epimerase -
           Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM
           861)
          Length = 309

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 39/161 (24%), Positives = 73/161 (45%)
 Frame = +2

Query: 281 HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTY 460
           ++ HLAAM      ++   +     N++    +L A    NVKKV+   S+ ++ +    
Sbjct: 72  YIFHLAAMASVPL-SVNDPIKCNDNNVNSTIKLLTAAKNQNVKKVIFSSSSAVYGNNANM 130

Query: 461 PIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKS 640
           P+ E+ +    P S    Y+ +K   ++  + + ESYG    ++   NVFGP  + + + 
Sbjct: 131 PLKESELMM--PTSP---YAASKANCELYLQAFEESYGLKSIALRYFNVFGPKQDKNSQY 185

Query: 641 SHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXIS 763
           + VIP  I   D  +    P    DG+     D +F+  ++
Sbjct: 186 AAVIPNFI---DAILNNEHPIIYGDGQQTR--DFIFVKDVA 221


>UniRef50_Q0W7F9 Cluster: Putative UDP-glucose 4-epimerase; n=1;
           uncultured methanogenic archaeon RC-I|Rep: Putative
           UDP-glucose 4-epimerase - Uncultured methanogenic
           archaeon RC-I
          Length = 306

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 36/129 (27%), Positives = 60/129 (46%)
 Frame = +2

Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 463
           V HLAA +  +  ++ + +  F  N     N+L+   K  VKK V   S  ++      P
Sbjct: 70  VYHLAA-ISNVDASIRNPIRTFETNAMGTANVLEEARKAGVKKFVYVSSAHVYGVPQYLP 128

Query: 464 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKSS 643
           IDE   H   P  +   Y+ +K   + + + Y  SYG  +  + P N+FGP  +     S
Sbjct: 129 IDEK--HPVVPREA---YAASKIAAENIVQAYGNSYGIEYAILRPFNIFGPGQD----PS 179

Query: 644 HVIPALIRR 670
            +IP +I++
Sbjct: 180 FLIPGVIKQ 188


>UniRef50_Q9ABX8 Cluster: UDP-glucose 4-epimerase; n=1; Caulobacter
           vibrioides|Rep: UDP-glucose 4-epimerase - Caulobacter
           crescentus (Caulobacter vibrioides)
          Length = 327

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 32/117 (27%), Positives = 55/117 (47%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GD+RD  + +A+FA + P  V+H AA +  +  ++ +   FF  N+     +++A  +  
Sbjct: 50  GDIRDAARLDAVFAAYAPVAVLHFAARI-EVGESVKNPGAFFDTNVGGTITLIEAARRAG 108

Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574
           VK VV   +   F D    P+ ET  H   P +    Y  +K M++     Y+   G
Sbjct: 109 VKVVVFSSTCATFGDPVDLPMKET--H---PQAPLNPYGRSKLMVEQALADYDRYVG 160


>UniRef50_Q70PA0 Cluster: Putative uncharacterized protein; n=1;
           Melittangium lichenicola|Rep: Putative uncharacterized
           protein - Melittangium lichenicola
          Length = 320

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 31/130 (23%), Positives = 59/130 (45%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           D+RD      LF   +P  V+HLAA VG    + + + ++   N++    +L+ C +  V
Sbjct: 61  DIRDAKACRELFDGARPERVVHLAARVGVRTLD-SESPEYAETNVTGFLQVLELCRRSRV 119

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586
           + +V   S+ ++   +  P  E    + P       Y+  KR  +++   Y+  Y    T
Sbjct: 120 EHLVFASSSSVYGAGSDMPFSEDSAADRPLSL----YAATKRANEMMAHAYSHQYAMPIT 175

Query: 587 SVIPCNVFGP 616
            +   +V+GP
Sbjct: 176 GLRLFSVYGP 185


>UniRef50_Q9KDV3 Cluster: UDP-glucose 4-epimerase; n=124; cellular
           organisms|Rep: UDP-glucose 4-epimerase - Bacillus
           halodurans
          Length = 334

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 37/155 (23%), Positives = 69/155 (44%), Gaps = 7/155 (4%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAA--MVGGLFHNMAHNLDFFRENMSINDNILQACHK 397
           GD+RD    + +F  H    VIH AA  +VG    ++   ++++  N+     +L+   +
Sbjct: 49  GDIRDDQLLDTIFTTHSIDTVIHFAANSLVG---ESVKQPIEYYENNVIGTHTLLKKMLE 105

Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577
           ++VKK+V   +   + +    PI E    + P   +N  Y   K  I+ +     E+YG 
Sbjct: 106 HDVKKIVFSSTAATYGEPVQIPIQE----SDPTIPTN-PYGETKLAIEKMFHWCQEAYGL 160

Query: 578 MFTSVIPCNVFGPHDNFSL-----KSSHVIPALIR 667
            +  +   N  G   N  +       SH+IP +++
Sbjct: 161 QYVCLRYFNAAGADPNGRIGEDHSPESHLIPIVLQ 195


>UniRef50_Q832Q5 Cluster: NAD-dependent epimerase/dehydratase family
           protein; n=6; Lactobacillales|Rep: NAD-dependent
           epimerase/dehydratase family protein - Enterococcus
           faecalis (Streptococcus faecalis)
          Length = 324

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 40/183 (21%), Positives = 86/183 (46%), Gaps = 3/183 (1%)
 Frame = +2

Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400
           +G + D+   E +  +++  ++ HLAA +  +  ++A  ++  + N      +L+   KY
Sbjct: 54  EGSVTDQQLMEKVLQEYQFDYIFHLAA-IASVADSVARPVETHQVNFESVLQLLELIRKY 112

Query: 401 --NVKKVVSCLSTCIFPDKTTYPI-DETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESY 571
             ++K++V   S  ++ D+ T P  +E+++    P++ +    +A     VLN  Y   Y
Sbjct: 113 QKDLKRLVFASSAAVYGDEPTLPKQEESVIRPLTPYAVD---KFASEKY-VLN--YCHLY 166

Query: 572 GCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFI 751
               ++V   NV+GP+ N +   S VI  ++      +   + TF   G+     D +F+
Sbjct: 167 DVPTSAVRFFNVYGPNQNPNSPYSGVISIVMDSYKRLLANQEVTFNIFGDGKQSRDFVFV 226

Query: 752 HXI 760
             +
Sbjct: 227 EDV 229


>UniRef50_O54385 Cluster: UDP-glucose epimerase; n=11; cellular
           organisms|Rep: UDP-glucose epimerase - Brucella abortus
          Length = 335

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 1/135 (0%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GD+RD+   E +  +HK T VIH A +   +  +    L ++  N+     +LQA     
Sbjct: 57  GDIRDRALMEQVIKRHKCTAVIHFAGL-KAVGESSEKPLLYYDCNVLGTLRLLQAMEATG 115

Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMI-DVLNRGYNESYGCM 580
           VKK+V   S  ++ D    PI E       P S+   Y   K +I D+L   YN      
Sbjct: 116 VKKLVFSSSATVYGDPDKLPITEDQ-----PLSATNPYGRTKLVIEDMLRDLYNSDNSWA 170

Query: 581 FTSVIPCNVFGPHDN 625
              +   N  G H++
Sbjct: 171 IAILRYFNPVGAHES 185


>UniRef50_A6CLM3 Cluster: UDP-glucose 4-epimerase; n=1; Bacillus sp.
           SG-1|Rep: UDP-glucose 4-epimerase - Bacillus sp. SG-1
          Length = 306

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 43/165 (26%), Positives = 71/165 (43%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           ++ DK  +  +F K +P  VIH+AA V      M   +D    N+    N+L  C KY V
Sbjct: 50  NITDKNLSN-VFDKERPDAVIHMAAQVDVSRSVMEPIMDA-EVNILGTINVLNECVKYKV 107

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586
           KKVV   ++ ++ +     I E    N      +F Y  +K   ++    + + +G  +T
Sbjct: 108 KKVVYSSTSAVYGENVASEISE----NEKIMPISF-YGISKYTPELYLEAFFKIHGLKYT 162

Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGE 721
            +   NV+G       +   VIP  I  +   M+   P    DG+
Sbjct: 163 ILRYSNVYGERQGIKGEGG-VIPIFIHEL---MEDRSPVIFGDGK 203


>UniRef50_O28263 Cluster: UDP-glucose 4-epimerase; n=1;
           Archaeoglobus fulgidus|Rep: UDP-glucose 4-epimerase -
           Archaeoglobus fulgidus
          Length = 307

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 36/112 (32%), Positives = 58/112 (51%)
 Frame = +2

Query: 257 LFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTC 436
           +F KH+   VIH AA +  +    +H +D FR N+    NIL+AC  ++V+KVV   S  
Sbjct: 50  VFRKHEIEGVIHAAAELS-VKAEKSH-VDAFRANVEGALNILEACRVFDVEKVVFTSSHS 107

Query: 437 IFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSV 592
           ++  + +YP  E   +  P   + F Y   K   ++L   Y+ +YG  F +V
Sbjct: 108 VYGPR-SYPFTE-FSYRDP---TTF-YGATKACSEILGTYYSYTYGIDFRAV 153


>UniRef50_A3ERU6 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=2; Bacteria|Rep: Nucleoside-diphosphate-sugar
           epimerase - Leptospirillum sp. Group II UBA
          Length = 316

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 42/166 (25%), Positives = 79/166 (47%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GD+R     E   A    T V H AA VG +  ++A   D    N++   N+L    ++ 
Sbjct: 53  GDVRSFADIEK--ALEGVTFVFHQAA-VGSVPRSIADPFDTQTANVNGTLNLLWKAKEFG 109

Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583
           V++VV   S+ ++ D    P  ET++ +  P S    Y+ +K   ++  + +++++G   
Sbjct: 110 VQRVVIAGSSSVYGDTPGMPRVETLLPS--PLSP---YALSKLSQELFGKIFSKTFGLDT 164

Query: 584 TSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGE 721
            ++   N+FGP  +   + + VIP  +R +   ++K   T    GE
Sbjct: 165 VTLRYFNIFGPRQDPRSEYAAVIPRFVRAI---LKKDAVTINGTGE 207


>UniRef50_Q8R8R8 Cluster: UDP-glucose 4-epimerase; n=15;
           Bacteria|Rep: UDP-glucose 4-epimerase -
           Thermoanaerobacter tengcongensis
          Length = 329

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 41/176 (23%), Positives = 82/176 (46%), Gaps = 11/176 (6%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAA--MVGGLFHNMAHNLDFFRENMSINDNILQACHK 397
           GDLRD+   + +F+++    V+H AA  +VG    ++ +   ++  N+    ++L+A  K
Sbjct: 49  GDLRDEDFLDKVFSENDIEAVMHFAASSLVG---ESVENPFKYYENNVCGTLSLLKAMKK 105

Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577
           + VKK+V   +  ++ +    PI+E          +N  Y   K  I+ + +  + +YG 
Sbjct: 106 HGVKKIVFSSTAAVYGEPERIPIEE----EDRTEPTN-PYGETKLAIEKMLKWADAAYGI 160

Query: 578 MFTSVIPCNVFGPHDNFSL-----KSSHVIPALIR----RMDDAMQKGDPTFXSDG 718
            + ++   NV G  +   +       +H+IP +++    + D  M  GD     DG
Sbjct: 161 KYVALRYFNVAGALETGEIGEDHSPETHLIPIILQVALGKRDKVMIYGDDYPTKDG 216


>UniRef50_Q83W21 Cluster: Ata17 protein; n=9; Bacteria|Rep: Ata17
           protein - Streptomyces capreolus
          Length = 384

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 37/147 (25%), Positives = 57/147 (38%), Gaps = 2/147 (1%)
 Frame = +2

Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFP--DKTT 457
           V  LAA +GG+    A++    + N  I+ N L+A  K  V +     S C++P   +  
Sbjct: 115 VYSLAADMGGMGFISANHATIMKNNSLIDLNTLEAARKARVNRFFYASSACVYPAYRQNI 174

Query: 458 YPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLK 637
             +      +  P +   GY + K   + L   Y E YG         NV+GP+  +   
Sbjct: 175 TEVVGLREEDAYPAAPEDGYGWEKLNTEHLCSYYREEYGLPVRVARLHNVYGPYCTYDGG 234

Query: 638 SSHVIPALIRRMDDAMQKGDPTFXSDG 718
                 AL R+   A   G      DG
Sbjct: 235 REKSPAALARKAALAEPGGRMEIWGDG 261


>UniRef50_Q9WYX9 Cluster: UDP-glucose 4-epimerase, putative; n=5;
           Thermotogaceae|Rep: UDP-glucose 4-epimerase, putative -
           Thermotoga maritima
          Length = 309

 Score = 43.6 bits (98), Expect = 0.006
 Identities = 35/134 (26%), Positives = 59/134 (44%), Gaps = 2/134 (1%)
 Frame = +2

Query: 230 LRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVK 409
           + D+   E +F+ H+P +V HLAA             D  + N+  +  +L+   KY VK
Sbjct: 52  IEDEEMMERIFSLHRPEYVFHLAAQASVAISVREPARD-AKTNIIGSLVLLEKSIKYGVK 110

Query: 410 K-VVSCLSTCIFPDKT-TYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583
           K + S     I+ +    +P  ET +    PH  +  Y  AK   ++    +   YG  +
Sbjct: 111 KFIFSSTGGAIYGENVKVFPTPETEI----PHPIS-PYGIAKYSTEMYLEFFAREYGLKY 165

Query: 584 TSVIPCNVFGPHDN 625
           T +   NV+GP  +
Sbjct: 166 TVLRYANVYGPRQD 179


>UniRef50_Q0C2X5 Cluster: UDP-glucose 4-epimerase; n=1; Hyphomonas
           neptunium ATCC 15444|Rep: UDP-glucose 4-epimerase -
           Hyphomonas neptunium (strain ATCC 15444)
          Length = 335

 Score = 43.6 bits (98), Expect = 0.006
 Identities = 31/120 (25%), Positives = 56/120 (46%), Gaps = 2/120 (1%)
 Frame = +2

Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAA--MVGGLFHNMAHNLDFFRENMSINDNILQACH 394
           +GDL      EA F+  KP  V H AA  +VG    ++     ++R N     N+L A  
Sbjct: 50  EGDLNSPGDIEAAFSAIKPDAVAHFAASTLVG---ESVTEPGKYYRNNTFTTLNVLDAMQ 106

Query: 395 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574
           ++N + ++   +  IF    T    E +  + P +  N  Y  +K M++ +  G++ ++G
Sbjct: 107 RHNTRAIIFSSTCAIFGHAQT----EFLAEDHPKNPIN-PYGMSKLMVEQMLAGFDHAHG 161


>UniRef50_A7HI28 Cluster: NAD-dependent epimerase/dehydratase; n=9;
           Bacteria|Rep: NAD-dependent epimerase/dehydratase -
           Anaeromyxobacter sp. Fw109-5
          Length = 373

 Score = 43.6 bits (98), Expect = 0.006
 Identities = 32/131 (24%), Positives = 59/131 (45%), Gaps = 1/131 (0%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRE-NMSINDNILQACHKYN 403
           D+ D+   +A+  + +P +V+HLAA VG    N   N   + E N+    N+L  C +  
Sbjct: 103 DVADREALDAVLDEAEPEYVVHLAAQVG--VRNSVRNPRAYAETNLDGFFNVLDGCARRG 160

Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583
           V+ +V   S+ ++      P  E    +   H  +F Y+  K+  +++   Y+       
Sbjct: 161 VRHLVYASSSSVYGSNEKVPFSE---EDPVDHPISF-YAATKKANEIMAHAYSHLNRLPT 216

Query: 584 TSVIPCNVFGP 616
           T +    V+GP
Sbjct: 217 TGLRFFTVYGP 227


>UniRef50_Q8TXF0 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=1; Methanopyrus kandleri|Rep:
           Nucleoside-diphosphate-sugar epimerase - Methanopyrus
           kandleri
          Length = 309

 Score = 43.6 bits (98), Expect = 0.006
 Identities = 49/181 (27%), Positives = 81/181 (44%), Gaps = 2/181 (1%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           D+ D    E  F +++P  VIHLAA V  + ++M       R N     N++    +++V
Sbjct: 53  DVTDPRAVERTFREYRPEAVIHLAAQV-NVRYSMESPFVDARINALGTLNLVSLAAEHDV 111

Query: 407 KKVVSCLS-TCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583
           ++ V   S   ++ +    P+DE   H   P  SN+G S  K   +   R Y E  G  +
Sbjct: 112 ERFVYASSGGAVYGEPEYLPVDEE--HPTRP-ISNYGVS--KLAGEYYVRVYAERDGFEY 166

Query: 584 TSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDP-TFXSDGEAXNHSDSLFIHXI 760
             +   NV+GP  +     + VIP  + R      +G+P T   DGE     D +F+  +
Sbjct: 167 VILRYANVYGPRQD-PRGEAGVIPIFLLR----AARGEPLTIFGDGEQTR--DFVFVEDV 219

Query: 761 S 763
           +
Sbjct: 220 A 220


>UniRef50_Q8THP9 Cluster: DTDP-glucose 4,6-dehydratase; n=3;
           Methanosarcina|Rep: DTDP-glucose 4,6-dehydratase -
           Methanosarcina acetivorans
          Length = 298

 Score = 43.2 bits (97), Expect = 0.008
 Identities = 42/149 (28%), Positives = 66/149 (44%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GD+ D +  E   A      V H AA+V     +    ++ FR N     N+LQAC +  
Sbjct: 52  GDICDPSSVEK--AVSGMDCVFHEAALVSVPL-SCEKPVEAFRINTLGTLNVLQACVRAG 108

Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583
           V+K V+  S  ++ +    P  E M    P  +S   Y+ +K   + L R + E +G   
Sbjct: 109 VEKFVTASSAAVYGNNPELPKRENMY---PEPAS--PYAISKLDGEYLARMFYEEHGLRT 163

Query: 584 TSVIPCNVFGPHDNFSLKSSHVIPALIRR 670
           T +   NV+GP  +     + VIP  + R
Sbjct: 164 TCLRYFNVYGPRQDPKSPYAAVIPIFLER 192


>UniRef50_Q9RWF7 Cluster: UDP-glucose 4-epimerase, putative; n=63;
           cellular organisms|Rep: UDP-glucose 4-epimerase,
           putative - Deinococcus radiodurans
          Length = 344

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 37/150 (24%), Positives = 64/150 (42%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GD+RD     AL    +   V HLAA++   +  +A    +   N++   N+L+A     
Sbjct: 74  GDVRDAGSVRALMRDVQT--VYHLAALIAIPYSYVAPR-SYVETNITGTLNVLEAARDLG 130

Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583
             +V+   ++ ++    + PI     H   P      YS  K   D L   Y  S+G   
Sbjct: 131 TGRVIHTSTSEVYGTARSVPI-----HESHPLQGQSPYSATKIGADKLAESYFLSFGLPV 185

Query: 584 TSVIPCNVFGPHDNFSLKSSHVIPALIRRM 673
            ++ P N +GP  +    +  VIP +I ++
Sbjct: 186 VTLRPFNTYGPRQS----ARAVIPTIISQL 211


>UniRef50_Q6MF46 Cluster: Probable UDP-glucuronat epimerase; n=2;
           cellular organisms|Rep: Probable UDP-glucuronat
           epimerase - Protochlamydia amoebophila (strain UWE25)
          Length = 327

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 28/132 (21%), Positives = 64/132 (48%)
 Frame = +2

Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400
           +GD+++  + +     H+ TH+IHLAA   G+ +++     + + N+    NIL+ C  +
Sbjct: 69  EGDIQNYEKLQNSILLHQTTHLIHLAAQ-AGVRYSLQEPATYLKTNVDGFLNILEICRSH 127

Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580
              K++   S+ ++   T  P   ++       +S +G +  K+  +++ + Y+  +G  
Sbjct: 128 PHLKLIYASSSSVYGLNTKVPF--SLEDRTDQQASLYGVT--KKTNELMAKTYHHLFGIS 183

Query: 581 FTSVIPCNVFGP 616
              +    V+GP
Sbjct: 184 SIGLRFFTVYGP 195


>UniRef50_Q9JRN7 Cluster: Putative uncharacterized protein; n=1;
           Aggregatibacter actinomycetemcomitans|Rep: Putative
           uncharacterized protein - Actinobacillus
           actinomycetemcomitans (Haemophilusactinomycetemcomitans)
          Length = 294

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 44/181 (24%), Positives = 79/181 (43%), Gaps = 2/181 (1%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           DL +    +++  K KP  ++HLAA+    F    + + F+  N    +N+L++    NV
Sbjct: 38  DLTNPCSVQSVLEKTKPDFIVHLAALT---FVPNNNPITFYLVNTIGTENLLRSIVDLNV 94

Query: 407 KKV-VSCLSTC-IFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580
            K+ V C ST  I+  + T  + E++      H     YS +K  ++ +   Y    G  
Sbjct: 95  AKLGVLCFSTAGIYGIQETKLLSESLTPKPVNH-----YSMSKHCMEHIVNKYRCFRG-- 147

Query: 581 FTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXI 760
            T V P NV G   N +     ++ A +++ D  ++ G+     D  + N    +    I
Sbjct: 148 ITVVRPFNVLGLGQNINFLVPKMVSAFVKK-DKTIELGNLDSVRDFISVNDCCDIIYRLI 206

Query: 761 S 763
           S
Sbjct: 207 S 207


>UniRef50_A3PE63 Cluster: UDP-glucose 4-epimerase; n=1;
           Prochlorococcus marinus str. MIT 9301|Rep: UDP-glucose
           4-epimerase - Prochlorococcus marinus (strain MIT 9301)
          Length = 330

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 35/157 (22%), Positives = 72/157 (45%), Gaps = 5/157 (3%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           D+R+++  + L  K KP +++H AA    +  ++   LD+   N+    ++ + C +  +
Sbjct: 53  DIREESSFKELLLKIKPDYLVHFAAS-AYVSESIFKPLDYISNNIDGMRSVCKICSEIKI 111

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586
             V S  S  ++ +    PI+E+   N  P S    Y   K   + + +  + +YG  + 
Sbjct: 112 PIVFSS-SCSVYGEAKNVPINESEPLN--PLSP---YGETKLFCEKILKWCSNAYGLRWV 165

Query: 587 SVIPCNVFGPHDNFSL-----KSSHVIPALIRRMDDA 682
           S+   N  G  ++  +       +H+IP  IR + D+
Sbjct: 166 SLRYFNAAGADEDLEIGEKHDPETHIIPLAIRALGDS 202


>UniRef50_Q9YCT1 Cluster: DTDP-glucose 4,6-dehydratase; n=2;
           Thermoprotei|Rep: DTDP-glucose 4,6-dehydratase -
           Aeropyrum pernix
          Length = 330

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 36/139 (25%), Positives = 64/139 (46%), Gaps = 1/139 (0%)
 Frame = +2

Query: 212 GSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC 391
           G   GD+ D+ Q   +  + +P  V++ AA    +  ++     F R N+     IL+A 
Sbjct: 51  GFMRGDIADEEQFGRVLTEFEPDVVVNFAAETH-VDRSINEPAPFMRTNIIGVFTILEAI 109

Query: 392 HKYNVKKVVSCLSTC-IFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNES 568
            K   + V+  +ST  ++ D      + T      P + +  YS +K   D+L + Y  +
Sbjct: 110 RKRIDQIVLLHVSTDEVYGDLWNTGKEAT---ESDPLNPSSPYSASKASGDLLIKAYGRT 166

Query: 569 YGCMFTSVIPCNVFGPHDN 625
           YG  +  V PCN +GP+ +
Sbjct: 167 YGLKYRIVRPCNNYGPYQH 185


>UniRef50_A7CY79 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Opitutaceae bacterium TAV2|Rep: NAD-dependent
           epimerase/dehydratase - Opitutaceae bacterium TAV2
          Length = 349

 Score = 42.3 bits (95), Expect = 0.014
 Identities = 32/145 (22%), Positives = 57/145 (39%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           D+RD    E  FA H P H ++  A   G+  ++     +   N+    N+L+AC  ++V
Sbjct: 79  DIRDPAAIERTFATHHPIHAVYHLAARAGVRPSIHSPRLYLSTNIDGTLNLLEACRAHHV 138

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586
              +   S+ ++      P  ET     P   +   Y+ +K   + L   Y   +G    
Sbjct: 139 PDFILASSSSVYGANPKTPFAET----DPIQRTLSPYAASKLAAEQLCSNYAHLHGLRCL 194

Query: 587 SVIPCNVFGPHDNFSLKSSHVIPAL 661
            +    V+GP     L  +    A+
Sbjct: 195 CLRLFTVYGPRQRPDLAIARFTAAI 219


>UniRef50_Q2SII8 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=3; Gammaproteobacteria|Rep:
           Nucleoside-diphosphate-sugar epimerase - Hahella
           chejuensis (strain KCTC 2396)
          Length = 319

 Score = 41.9 bits (94), Expect = 0.018
 Identities = 35/130 (26%), Positives = 59/130 (45%), Gaps = 3/130 (2%)
 Frame = +2

Query: 236 DKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKV 415
           +K   E +F KH  T VIHL  M+    + M      +  N+  +  +L  CHKY+++KV
Sbjct: 58  NKRGFEDIFRKHNITGVIHLGRMIASEENRMRR----YNSNVLGSHRLLDLCHKYHIQKV 113

Query: 416 VSCLSTCIFPDKTTYPIDETMVHNGPP-HSSNFGYSYAKRM-IDVLNRGYNESYGCMFTS 589
           +  LST        Y  +  ++  G P  ++         + ++ L   Y   Y  +  +
Sbjct: 114 I-ILSTYHVYGANAY--NPALIDEGAPLKAAELTMDLIDSVELENLANIYLWKYPDLNIT 170

Query: 590 VI-PCNVFGP 616
           V+ PCN+ GP
Sbjct: 171 VLRPCNIVGP 180


>UniRef50_Q12UG3 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Euryarchaeota|Rep: NAD-dependent epimerase/dehydratase -
           Methanococcoides burtonii (strain DSM 6242)
          Length = 299

 Score = 41.9 bits (94), Expect = 0.018
 Identities = 38/146 (26%), Positives = 59/146 (40%)
 Frame = +2

Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 463
           +IH AA +  +  +M       + N+    N+L+     N+++ V   S   + +    P
Sbjct: 66  IIHTAAQIS-VVRSMNEPFFDAQNNIMGTLNLLEEARHANIERFVYFSSAATYGNPLKVP 124

Query: 464 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKSS 643
           I ET  H   P S       A     ++   YN++YG   T + P N++ P  + S   S
Sbjct: 125 IGET--HPQEPLSPYGASKLAGEKYCIM---YNKAYGLPTTCIRPFNIYSPRQDPSNPYS 179

Query: 644 HVIPALIRRMDDAMQKGDPTFXSDGE 721
            VI   I   D       PT   DGE
Sbjct: 180 GVISKFI---DKVSGGASPTIFGDGE 202


>UniRef50_Q661H6 Cluster: Nucleotide sugar epimerase; n=3; Borrelia
           burgdorferi group|Rep: Nucleotide sugar epimerase -
           Borrelia garinii
          Length = 355

 Score = 41.5 bits (93), Expect = 0.024
 Identities = 32/133 (24%), Positives = 63/133 (47%), Gaps = 2/133 (1%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC--HKY 400
           D+ +K +   LF ++K THV HLAA   G+  ++ +   +   N+    N+L  C  +K 
Sbjct: 76  DILNKDKLLKLFKEYKFTHVCHLAAQ-AGIRDSLENPDSYVSINIVGFFNVLDVCRVYKE 134

Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580
           N+K  V   ++ ++      P  E  + +   H  N  Y+ +K+  +++   Y+ S+   
Sbjct: 135 NIKHFVYASTSSVYGINENIPSSEDSITD---HPLNL-YAASKKSNEMIAHAYSASFNIP 190

Query: 581 FTSVIPCNVFGPH 619
            T +    V+G +
Sbjct: 191 TTGLRFFTVYGTY 203


>UniRef50_Q0YI68 Cluster: NAD-dependent
           epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR:3-beta hydroxysteroid
           dehydrogenase/isomerase:Polysaccharide biosynthesis
           protein CapD:dTDP- 4-dehydrorhamnose
           reductase:Nucleotide sugar epimerase; n=3; cellular
           organisms|Rep: NAD-dependent
           epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR:3-beta hydroxysteroid
           dehydrogenase/isomerase:Polysaccharide biosynthesis
           protein CapD:dTDP- 4-dehydrorhamnose
           reductase:Nucleotide sugar epimerase - Geobacter sp.
           FRC-32
          Length = 328

 Score = 41.5 bits (93), Expect = 0.024
 Identities = 33/144 (22%), Positives = 62/144 (43%)
 Frame = +2

Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400
           +GD+RD+    A+F +  P  VIHLAA   G+  ++ + L +   N+    N+L+A    
Sbjct: 64  EGDIRDEEFIRAIFTQELPDAVIHLAA-AAGVRPSIDNPLLYEEVNVRGTMNLLEAAKAI 122

Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580
            V+  +   S+ ++ +    P  E      P  +    Y+  K+  +++   Y+  Y   
Sbjct: 123 GVRLFLFASSSSVYGNNPKVPFAEA----DPVDNPISPYAATKKAGELICHTYHHLYDIN 178

Query: 581 FTSVIPCNVFGPHDNFSLKSSHVI 652
              +    V+GP     L  S  +
Sbjct: 179 IACLRFFTVYGPRQRPDLAISKFV 202


>UniRef50_Q5FQW6 Cluster: UDP-glucose 4-epimerase; n=3;
           Bacteria|Rep: UDP-glucose 4-epimerase - Gluconobacter
           oxydans (Gluconobacter suboxydans)
          Length = 328

 Score = 41.1 bits (92), Expect = 0.032
 Identities = 32/99 (32%), Positives = 50/99 (50%), Gaps = 5/99 (5%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAM--VGGLFHNMAHNLDFFRENMSINDNILQACHKY 400
           DL D   T A+ A+ K   V+H AA+  VG    +  H   + R+N     N++Q C ++
Sbjct: 51  DLLDYAATSAVVAQGKWDGVLHFAALSLVGDSMRDPFH---YLRQNYLTALNLVQICVEH 107

Query: 401 NVKKVVSCLSTCIF--PDKTTYPIDETM-VHNGPPHSSN 508
            VKK+V   +  +F  P++   PI ET  V  G P+  +
Sbjct: 108 GVKKIVFSSTAALFGGPERLD-PIPETAPVQPGSPYGES 145


>UniRef50_A6PV21 Cluster: UDP-glucose 4-epimerase; n=1; Victivallis
           vadensis ATCC BAA-548|Rep: UDP-glucose 4-epimerase -
           Victivallis vadensis ATCC BAA-548
          Length = 307

 Score = 41.1 bits (92), Expect = 0.032
 Identities = 42/174 (24%), Positives = 77/174 (44%), Gaps = 9/174 (5%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAA--MVGGLFHNMAHNLDFFRENMSINDNILQACHK 397
           G+L D+ + +++  + K   ++H AA  +VG    +M     +FR N++   N+  A  +
Sbjct: 34  GNLSDREKIKSVCREGKFDAIMHFAAFSLVG---ESMKDPSKYFRNNIANGINLADAAVE 90

Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577
             VK  V   +   F    + PI E       P +    Y  +K   + + + Y+E YG 
Sbjct: 91  SGVKMFVFSSTAATFGQPESIPIKE--FDRQIPINP---YGESKLCFEKILKWYHEIYGI 145

Query: 578 MFTSVIPCNVFGPHDNFS---LKSSHVIPALIR----RMDDAMQKGDPTFXSDG 718
            + ++   N  G  +NF       +H+IP +++    + D  M  GD    +DG
Sbjct: 146 NYAALRYFNAAGATENFGEDHRPETHLIPLILQTVRGKRDKLMLYGDDYDTADG 199


>UniRef50_A0B5G2 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Methanomicrobia|Rep: NAD-dependent epimerase/dehydratase
           - Methanosaeta thermophila (strain DSM 6194 / PT)
           (Methanothrixthermophila (strain DSM 6194 / PT))
          Length = 310

 Score = 41.1 bits (92), Expect = 0.032
 Identities = 39/147 (26%), Positives = 66/147 (44%)
 Frame = +2

Query: 281 HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTY 460
           +V+H AA+   +  ++   +   R N+    ++L A     VK+VV   S+ ++ D    
Sbjct: 72  YVLHQAALPS-VQRSIMDPMATNRSNIDGTLSVLVAAMDCGVKRVVFASSSAVYGDSPEL 130

Query: 461 PIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKS 640
           P  E+++    P S    Y+  K + +   R + E YG    S+   NVFGP  + + + 
Sbjct: 131 PKRESLIPR--PMSP---YAVTKLVGEHYCRVFYEIYGIECVSLRYFNVFGPGQDPASEY 185

Query: 641 SHVIPALIRRMDDAMQKGDPTFXSDGE 721
           + VIP  I   D  +    P    DGE
Sbjct: 186 AAVIPKFI---DAVLSGSQPVVYGDGE 209


>UniRef50_Q9LIS3 Cluster: UDP-glucuronate 4-epimerase 6; n=40;
           Viridiplantae|Rep: UDP-glucuronate 4-epimerase 6 -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 460

 Score = 41.1 bits (92), Expect = 0.032
 Identities = 34/133 (25%), Positives = 57/133 (42%), Gaps = 1/133 (0%)
 Frame = +2

Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400
           +GDL D      LF     TH++HLAA   G+ + M +   +   N++   N+L+     
Sbjct: 169 EGDLNDGPLLRKLFDVVPFTHILHLAAQ-AGVRYAMKNPQSYIASNIAGFVNLLEVAKAA 227

Query: 401 NVK-KVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577
           N +  +V   S+ ++   T  P  E    + P       Y+  K+  + +   YN  YG 
Sbjct: 228 NPQPAIVWASSSSVYGLNTENPFSEEHRTDQPASL----YAATKKAGEEIAHTYNHIYGL 283

Query: 578 MFTSVIPCNVFGP 616
             T +    V+GP
Sbjct: 284 SLTGLRFFTVYGP 296


>UniRef50_P72903 Cluster: UDP-glucose-4-epimerase; n=20;
           Bacteria|Rep: UDP-glucose-4-epimerase - Synechocystis
           sp. (strain PCC 6803)
          Length = 340

 Score = 40.7 bits (91), Expect = 0.042
 Identities = 34/161 (21%), Positives = 73/161 (45%), Gaps = 1/161 (0%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GDL D  +   +F +H+   V+H A  +  +  ++ H L+++  N S   ++++ C  + 
Sbjct: 55  GDLADTERLHQVFHEHEILAVMHFAGSL-IVPESLIHPLNYYANNTSNTLSLIRCCQIFG 113

Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583
           V +++   +  ++ + ++ PI E  +    P   N  Y  +K   + + + Y +S    +
Sbjct: 114 VNRLIFSSTAAVYGNSSSNPISEAEI----PCPIN-PYGRSKLASEWIIQDYAKSSALQY 168

Query: 584 TSVIPCNVFGPHDNFSL-KSSHVIPALIRRMDDAMQKGDPT 703
             +   NV G      L + S     L+R + DA+    P+
Sbjct: 169 VILRYFNVAGADPEGRLGQMSKTTTHLVRSVCDAILNLKPS 209


>UniRef50_Q1VUQ5 Cluster: Sugar epimerase BlmG; n=2; Bacteria|Rep:
           Sugar epimerase BlmG - Psychroflexus torquis ATCC 700755
          Length = 359

 Score = 40.7 bits (91), Expect = 0.042
 Identities = 35/156 (22%), Positives = 59/156 (37%), Gaps = 7/156 (4%)
 Frame = +2

Query: 170 KRNSDYDSETWIFSGSKDGDLRDKTQTEALFAKHKPT---HVIHLAAMVGGLFHNMA--H 334
           K N ++     I     +GDLRD    E  F   +      V  LAA +GG  +     +
Sbjct: 34  KPNHEFWDHQLICDEYMEGDLRDPRIVEKAFENKQNVSYDEVYQLAADMGGALYIFTGEN 93

Query: 335 NLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSN-- 508
           + +    +  IN N+   C K  + +V    S C++P+      D         + +N  
Sbjct: 94  DANVMHNSALINLNVAHECVKNKIGRVFYSSSACMYPEHNQLDADNPNCEESSAYPANPD 153

Query: 509 FGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGP 616
             Y + K   + L   ++ +Y          N+FGP
Sbjct: 154 SEYGWEKLFSERLFLAFSRNYKLSVRVARFHNIFGP 189


>UniRef50_A4CBV8 Cluster: NAD dependent epimerase/dehydratase family
           protein; n=4; Proteobacteria|Rep: NAD dependent
           epimerase/dehydratase family protein - Pseudoalteromonas
           tunicata D2
          Length = 332

 Score = 40.3 bits (90), Expect = 0.055
 Identities = 32/130 (24%), Positives = 57/130 (43%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           DL D+     LFA  +   VIHLAA   G+ +++ + + +   N+     IL+ C    V
Sbjct: 61  DLADREAIANLFATEQFERVIHLAAQ-AGVRYSIENPMAYIDSNLVGMATILEGCRHNKV 119

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586
           + +V   S+ ++   T  P  E    + P       Y+  K+  +++   Y+  Y    T
Sbjct: 120 QHLVYASSSSVYGANTKIPFAEEDRVDYPVSL----YAATKKSNELMAHTYSHLYSLPTT 175

Query: 587 SVIPCNVFGP 616
            +    V+GP
Sbjct: 176 GLRFFTVYGP 185


>UniRef50_O26473 Cluster: DTDP-glucose 4,6-dehydratase related
           protein; n=2; Methanobacteriaceae|Rep: DTDP-glucose
           4,6-dehydratase related protein - Methanobacterium
           thermoautotrophicum
          Length = 334

 Score = 40.3 bits (90), Expect = 0.055
 Identities = 33/138 (23%), Positives = 65/138 (47%), Gaps = 3/138 (2%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           D+R+  Q E +F + K  +V HLAA   G ++   +  + ++ N+    ++L+   K   
Sbjct: 68  DVREYRQVERIFEEDKFDYVYHLAAEY-GRWNGEDYYENLWKTNVIGTKHMLRMQEKLGF 126

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNF---GYSYAKRMIDVLNRGYNESYGC 577
            +++   S  ++ D +    ++ MV N  P S  +    Y+  K   +++     E +G 
Sbjct: 127 -RMIFFSSAEVYGDYSGLMSEDVMVKN--PISDTYQMNDYAITKWAGELMCMNSAEMFGT 183

Query: 578 MFTSVIPCNVFGPHDNFS 631
               V P N +GPH+ +S
Sbjct: 184 ETVRVRPVNCYGPHEKYS 201


>UniRef50_A7DQX9 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Candidatus Nitrosopumilus maritimus SCM1|Rep:
           NAD-dependent epimerase/dehydratase - Candidatus
           Nitrosopumilus maritimus SCM1
          Length = 308

 Score = 40.3 bits (90), Expect = 0.055
 Identities = 30/110 (27%), Positives = 53/110 (48%)
 Frame = +2

Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 463
           VIHLAA +  +  ++ H     + N+  + N+L+AC K NVK  ++  S  ++ +    P
Sbjct: 71  VIHLAAKID-ILQSIEHPDQTHKINVEGSLNLLRACVKNNVKNFIAASSAAVYGNPKQIP 129

Query: 464 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFG 613
           + E  + N  P S    Y   K  ++   R +  +YG    ++   NV+G
Sbjct: 130 VTEFTIPN--PVSP---YGADKIALEFYLRAFCNAYGINGIALRFFNVYG 174


>UniRef50_Q5FRS4 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=1;
           Gluconobacter oxydans|Rep: UDP-N-acetylglucosamine
           4-epimerase - Gluconobacter oxydans (Gluconobacter
           suboxydans)
          Length = 322

 Score = 39.9 bits (89), Expect = 0.073
 Identities = 34/132 (25%), Positives = 57/132 (43%), Gaps = 2/132 (1%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTH-VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC-HKY 400
           D+      + L A+H     VIHLAA  G + H+M     +   N+     +L+AC H  
Sbjct: 61  DVASPAAMQDLVARHSDLEGVIHLAAQAG-VRHSMVDPYSYVTSNVMGQVALLEACRHLK 119

Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580
            +  VV   S+ ++    + P  ET     P    +  Y+  KR  ++++  Y   +G  
Sbjct: 120 KLTHVVYASSSSVYGRNQSVPFRETDRVERP----SSVYAVTKRAAELMSESYAYLHGIP 175

Query: 581 FTSVIPCNVFGP 616
            T +    V+GP
Sbjct: 176 QTGLRFFTVYGP 187


>UniRef50_Q1VGF9 Cluster: Putative uncharacterized protein; n=1;
           Psychroflexus torquis ATCC 700755|Rep: Putative
           uncharacterized protein - Psychroflexus torquis ATCC
           700755
          Length = 268

 Score = 39.9 bits (89), Expect = 0.073
 Identities = 25/88 (28%), Positives = 46/88 (52%), Gaps = 4/88 (4%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSIN----DNILQAC 391
           GD+RD +   +  A  +   V+HLAA V     ++  +++F +E + IN    DN+L +C
Sbjct: 4   GDVRDASTVHSAVAGCQA--VVHLAAQV-----SVPQSMEFPKETLEINVGGTDNLLNSC 56

Query: 392 HKYNVKKVVSCLSTCIFPDKTTYPIDET 475
           +   V + V   S  ++     +P+DE+
Sbjct: 57  NINGVSRFVLASSAAVYGTNDAFPLDES 84


>UniRef50_Q0LJ11 Cluster: NAD-dependent epimerase/dehydratase; n=4;
           Bacteria|Rep: NAD-dependent epimerase/dehydratase -
           Herpetosiphon aurantiacus ATCC 23779
          Length = 317

 Score = 39.9 bits (89), Expect = 0.073
 Identities = 38/136 (27%), Positives = 53/136 (38%)
 Frame = +2

Query: 272 KPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDK 451
           KP  V+HLAA      H +        EN+    N+L+ C    V  + S  S  ++ D 
Sbjct: 66  KPDVVVHLAA--NAKVHELVTYPHRALENVMTTYNVLEYCRHQQVPIIFSS-SREVYGDI 122

Query: 452 TTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFS 631
             Y  +E         S    YS +K   +     Y   Y   +      NV+G +DN  
Sbjct: 123 HRYLTEEAQADFVYTESP---YSASKISGEAFIYSYARCYNLPYLVFRFSNVYGRYDNDI 179

Query: 632 LKSSHVIPALIRRMDD 679
            +   VIP  IRRM D
Sbjct: 180 ERMERVIPLFIRRMRD 195


>UniRef50_A7GZ40 Cluster: dTDP-glucose 4,6-dehydratase; n=1;
           Campylobacter curvus 525.92|Rep: dTDP-glucose
           4,6-dehydratase - Campylobacter curvus 525.92
          Length = 345

 Score = 39.9 bits (89), Expect = 0.073
 Identities = 39/145 (26%), Positives = 66/145 (45%), Gaps = 10/145 (6%)
 Frame = +2

Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRE-NMSINDNILQACHK 397
           +GD+ D+   E++F K+    VIH AA       N  +    F E N+    N+L     
Sbjct: 62  EGDICDRLLLESIFDKYSIKEVIHFAAETH--VDNSINKPGIFIETNVLGTFNVLDVAKS 119

Query: 398 YNVK---KVVSCLSTCIFPDKTTYPIDETMVHNG-----PPHSSNFGYSYAKRMIDVLNR 553
           + ++   +      TC F   +T  +  T+  +G       ++ N  YS +K   D++ R
Sbjct: 120 FWMEGPFRYKPQYETCKFYHISTDEVYGTLGDSGYFTEKSNYAPNSPYSASKASSDMIVR 179

Query: 554 GYNESYGCMFTSVIPC-NVFGPHDN 625
            YN +YG M T +  C N +GP+ +
Sbjct: 180 SYNRTYG-MNTLITNCSNNYGPNQH 203


>UniRef50_Q81AP5 Cluster: CDP-abequose synthase; n=2; Bacillus
           cereus group|Rep: CDP-abequose synthase - Bacillus
           cereus (strain ATCC 14579 / DSM 31)
          Length = 319

 Score = 39.5 bits (88), Expect = 0.096
 Identities = 29/87 (33%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHN--LDFFRENMSINDNILQACHKY 400
           D+RDK Q +    K  P ++ HLAA   G+  N AH   +     N+    NI+QA    
Sbjct: 60  DIRDKKQVQDAIKKINPDYIFHLAAY--GV--NSAHTDYIHAIETNVIGTCNIIQAAKLV 115

Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMV 481
           N KK+++  S+  + +K   PI E M+
Sbjct: 116 NCKKIINFGSSSEYGNKME-PIHENML 141


>UniRef50_Q3ESA4 Cluster: DTDP-glucose 4,6-dehydratase; n=3;
           Firmicutes|Rep: DTDP-glucose 4,6-dehydratase - Bacillus
           thuringiensis serovar israelensis ATCC 35646
          Length = 320

 Score = 39.5 bits (88), Expect = 0.096
 Identities = 38/135 (28%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFR---ENMSIND-NILQAC 391
           GD++DK     LF  +      HLAA +     N+  ++D  R   EN +I   N+L+ C
Sbjct: 56  GDIKDKKLVAQLFENNSFDLCYHLAASI-----NVQDSIDDARATFENDTIGTFNLLEQC 110

Query: 392 HKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESY 571
             Y+VK V   +STC+  DK T   +   +    P      Y+ +K   + +   Y  +Y
Sbjct: 111 LNYDVKMVF--MSTCMVYDKAT---NIQGISELDPIKPASPYAGSKIAAENMVLSYYYAY 165

Query: 572 GCMFTSVIPCNVFGP 616
                 + P N +GP
Sbjct: 166 KLPVVVIRPFNTYGP 180


>UniRef50_A6DF55 Cluster: Putative uncharacterized protein; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Putative
           uncharacterized protein - Lentisphaera araneosa HTCC2155
          Length = 298

 Score = 39.5 bits (88), Expect = 0.096
 Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 3/136 (2%)
 Frame = +2

Query: 218 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 397
           + GD+ DK     L  K+  TH++H AA+        A+     + N+    N+L+A  +
Sbjct: 48  EQGDILDKESILRLLQKYAVTHLLHTAAL--RTSQCKANPEQAVQVNIIGTANVLEAIRE 105

Query: 398 Y-NVKKVVSCLSTCIF--PDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNES 568
           Y  ++ VV   +  ++  P   T P DE    N P  + N  Y+  K   + L   Y  S
Sbjct: 106 YAKLEHVVFISTAAVYKVPKDGTRP-DE----NSPVEALNL-YTSTKLAGEALVESYAHS 159

Query: 569 YGCMFTSVIPCNVFGP 616
           YG   + + P  ++GP
Sbjct: 160 YGLQCSVLRPQIIYGP 175


>UniRef50_A5M424 Cluster: UDP-glucose 4-epimerase; n=1;
           Streptococcus pneumoniae SP11-BS70|Rep: UDP-glucose
           4-epimerase - Streptococcus pneumoniae SP11-BS70
          Length = 342

 Score = 39.5 bits (88), Expect = 0.096
 Identities = 30/107 (28%), Positives = 48/107 (44%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           DL+++ + E +F +H    VIH A     +  ++   L ++  N+    NIL+   KY V
Sbjct: 61  DLKNEEKLENVFKRHNFDGVIHFAGYKA-VGESVVEPLKYYENNLLSTINILKLMKKYKV 119

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVL 547
              V   S  ++      P  ET     P  +SN  Y   K+ I+VL
Sbjct: 120 FNFVFSSSATVYESTPIMPFYET----NPLKASN-PYGRTKQYIEVL 161


>UniRef50_Q18EM3 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=1; Haloquadratum walsbyi DSM 16790|Rep:
           Nucleoside-diphosphate-sugar epimerase - Haloquadratum
           walsbyi (strain DSM 16790)
          Length = 339

 Score = 39.1 bits (87), Expect = 0.13
 Identities = 41/153 (26%), Positives = 69/153 (45%), Gaps = 7/153 (4%)
 Frame = +2

Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFP---DKT 454
           V HLAA  GG  +   +  +    NM++++ + +A  +  V+++    S C +P    + 
Sbjct: 77  VFHLAADHGGRGYISNYPANC-ATNMALDNIVYEAAAENGVERICFASSACTYPTDIQQE 135

Query: 455 TYPIDETMV---HNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDN 625
              + E MV     G  ++    Y +AK M +   + YNE Y    ++V     +GP +N
Sbjct: 136 RQRLHEEMVSFDERGGAYADEV-YGWAKLMGERSLQAYNEQYDIDTSAVRIFTAYGPREN 194

Query: 626 FSLKSSHVIPALIRRMDDAMQKGDP-TFXSDGE 721
                +H   A+I  M  AM + DP     DGE
Sbjct: 195 ----ETH---AIIAFMAKAMARQDPFQIWGDGE 220


>UniRef50_Q1YMT2 Cluster: UDP-glucose 4-epimerase; n=3;
           Alphaproteobacteria|Rep: UDP-glucose 4-epimerase -
           Aurantimonas sp. SI85-9A1
          Length = 341

 Score = 38.7 bits (86), Expect = 0.17
 Identities = 20/73 (27%), Positives = 41/73 (56%)
 Frame = +2

Query: 218 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 397
           + GD+RD  +  ++F++++P  +IH A ++  +  ++   L F+  N+S   +++ A   
Sbjct: 55  EQGDIRDTNRLRSVFSQYQPDAIIHFAGLI-EVAQSVRDPLAFYDNNVSGTLSLITAAEA 113

Query: 398 YNVKKVVSCLSTC 436
             V K+V   STC
Sbjct: 114 AGVDKIVFS-STC 125


>UniRef50_Q93VR3 Cluster: GDP-mannose 3,5-epimerase; n=21; cellular
           organisms|Rep: GDP-mannose 3,5-epimerase - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 377

 Score = 38.7 bits (86), Expect = 0.17
 Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 2/114 (1%)
 Frame = +2

Query: 281 HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTY 460
           HV +LAA +GG+    +++      N  I+ N+++A     +K+     S CI+P+    
Sbjct: 94  HVFNLAADMGGMGFIQSNHSVIMYNNTMISFNMIEAARINGIKRFFYASSACIYPEFKQL 153

Query: 461 PIDETMVHNGP--PHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGP 616
                 +      P      Y   K   + L + YN+ +G         N++GP
Sbjct: 154 ETTNVSLKESDAWPAEPQDAYGLEKLATEELCKHYNKDFGIECRIGRFHNIYGP 207


>UniRef50_Q42605 Cluster: UDP-glucose 4-epimerase; n=20;
           Viridiplantae|Rep: UDP-glucose 4-epimerase - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 351

 Score = 38.7 bits (86), Expect = 0.17
 Identities = 24/83 (28%), Positives = 39/83 (46%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GDLR+K   E LF+K +   VIH A +   +  ++ +   +F  N+    N+ +   KYN
Sbjct: 67  GDLRNKGDIEKLFSKQRFDAVIHFAGL-KAVGESVENPRRYFDNNLVGTINLYETMAKYN 125

Query: 404 VKKVVSCLSTCIFPDKTTYPIDE 472
            K +V   S  ++      P  E
Sbjct: 126 CKMMVFSSSATVYGQPEKIPCME 148


>UniRef50_UPI0000DAE763 Cluster: hypothetical protein
           Rgryl_01001156; n=1; Rickettsiella grylli|Rep:
           hypothetical protein Rgryl_01001156 - Rickettsiella
           grylli
          Length = 341

 Score = 38.3 bits (85), Expect = 0.22
 Identities = 21/84 (25%), Positives = 42/84 (50%)
 Frame = +2

Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400
           +GD+ D    + +F ++  + VIHLA +   +  ++ + L  +  N+     ++ A  K 
Sbjct: 58  EGDILDSNLLDHIFFENNISAVIHLAGL-KAVSESIKNPLKCYNNNVEGTLTLINAMRKS 116

Query: 401 NVKKVVSCLSTCIFPDKTTYPIDE 472
           NVKK++   S  ++ +    PI E
Sbjct: 117 NVKKLIFSSSAAVYGEPKCVPIRE 140


>UniRef50_Q9RSC3 Cluster: UDP-glucose 4-epimerase; n=1; Deinococcus
           radiodurans|Rep: UDP-glucose 4-epimerase - Deinococcus
           radiodurans
          Length = 394

 Score = 38.3 bits (85), Expect = 0.22
 Identities = 33/141 (23%), Positives = 58/141 (41%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GDL D     A     KP  +IH AA++  +  +M     ++R N+    N+LQ+  +  
Sbjct: 50  GDLLDAASIRAALEAQKPDAIIHFAALI-EVGESMRAPGRYYRNNVVGTLNLLQSIVETR 108

Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583
              +V   +  ++      PI E       P S    Y   KRM + +   ++ ++G  +
Sbjct: 109 KVPLVFSSTAAVYGTTDAVPIPEDAAMQ--PESV---YGETKRMSEQMIHAFHVAHGLPY 163

Query: 584 TSVIPCNVFGPHDNFSLKSSH 646
           T +   NV G      +  +H
Sbjct: 164 TVLRYFNVCGAAPGGDIGEAH 184


>UniRef50_Q65E95 Cluster: Putative uncharacterized protein; n=1;
           Bacillus licheniformis ATCC 14580|Rep: Putative
           uncharacterized protein - Bacillus licheniformis (strain
           DSM 13 / ATCC 14580)
          Length = 309

 Score = 38.3 bits (85), Expect = 0.22
 Identities = 29/117 (24%), Positives = 56/117 (47%)
 Frame = +2

Query: 275 PTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKT 454
           P +++HLAA V  +  +++  L+    N+  + +I++A  + NVKK+V   S  ++ +  
Sbjct: 68  PDYIVHLAAQVS-VAESVSDFLNDENINIRGSLHIIKAAGECNVKKIVFASSAAVYGNPD 126

Query: 455 TYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDN 625
             P+D    H   P S    Y   K  ++   +   + YG  +  +   NV+GP  +
Sbjct: 127 YLPVDTR--HQTNPGSP---YGLTKLTVENYLKLAYDLYGTEYCILRYSNVYGPRQD 178


>UniRef50_Q2WB63 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=2; Alphaproteobacteria|Rep:
           Nucleoside-diphosphate-sugar epimerase -
           Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
          Length = 333

 Score = 38.3 bits (85), Expect = 0.22
 Identities = 28/116 (24%), Positives = 52/116 (44%)
 Frame = +2

Query: 377 ILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRG 556
           +L+   K  V + V C S+ ++ +     ++E      P       Y  AK   ++  + 
Sbjct: 104 LLEEARKRQVSRFVYCSSSEVYGNGRDSLLNEDRTVCEPVTV----YGAAKLAGELYAKA 159

Query: 557 YNESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEA 724
           Y+ +YG     V P N +GP +++  + + VIP  + R+ + +    PT   DG A
Sbjct: 160 YHRTYGLPTVVVRPFNSYGPREHYKGQRAEVIPRFLIRVLNGL---PPTIFGDGSA 212


>UniRef50_Q8GP51 Cluster: Eps11G; n=11; Bacteria|Rep: Eps11G -
           Streptococcus thermophilus
          Length = 357

 Score = 38.3 bits (85), Expect = 0.22
 Identities = 30/132 (22%), Positives = 61/132 (46%), Gaps = 1/132 (0%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC-HKY 400
           G++ D      LF K+KP+ V++LAA    + +++ +   +   N+    NIL+AC H  
Sbjct: 78  GNIADTELITELFEKYKPSVVVNLAAQ-ADVRYSITNPDAYVESNLVSFFNILEACRHCE 136

Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580
           +++ +V   S+ ++      P       + P       Y+  K+  +++   Y++ Y   
Sbjct: 137 SLEHLVYASSSSVYGSNKKVPYSTDDKVDNPVSL----YAATKKSNELMAHAYSKLYNIP 192

Query: 581 FTSVIPCNVFGP 616
            T +    V+GP
Sbjct: 193 STGLRFFTVYGP 204


>UniRef50_Q7D561 Cluster: NAD-dependent epimerase/dehydratase family
           protein; n=20; Bacteria|Rep: NAD-dependent
           epimerase/dehydratase family protein - Mycobacterium
           tuberculosis
          Length = 322

 Score = 38.3 bits (85), Expect = 0.22
 Identities = 39/170 (22%), Positives = 68/170 (40%), Gaps = 1/170 (0%)
 Frame = +2

Query: 254 ALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLS- 430
           A+  +H+P  V HLAA +  +  ++A        N+     + +A  +  V+K+V   S 
Sbjct: 72  AILEQHRPEVVFHLAAQI-DVRRSVADPQFDAAVNVIGTVRLAEAARQTGVRKIVHTSSG 130

Query: 431 TCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVF 610
             I+     YP  ET      P      Y+  K   ++    +   YG   + + P NV+
Sbjct: 131 GSIYGTPPEYPTPET-----APTDPASPYAAGKVAGEIYLNTFRHLYGLDCSHIAPANVY 185

Query: 611 GPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXI 760
           GP      +  H    ++     A+  G PT    G+  N  D +F+  +
Sbjct: 186 GPR-----QDPHGEAGVVAIFAQALLSGKPT-RVFGDGTNTRDYVFVDDV 229


>UniRef50_Q4HQ86 Cluster: UDP-glucose 4-epimerase, putative; n=2;
           Proteobacteria|Rep: UDP-glucose 4-epimerase, putative -
           Campylobacter upsaliensis RM3195
          Length = 323

 Score = 38.3 bits (85), Expect = 0.22
 Identities = 35/134 (26%), Positives = 58/134 (43%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GDLRD    ++L        V+HL A++   +   A    +   N+    N+L+A  ++ 
Sbjct: 57  GDLRDSFFCDSLVKGVDA--VLHLGALIAIPYSYTAPQ-SYVDTNIQGTLNLLEASKRHG 113

Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583
           VK+ +   ++ ++      PIDE   H   P S    YS +K   D+L   Y  S+    
Sbjct: 114 VKRFIHTSTSEVYGSAIYTPIDEK--HPLQPQSP---YSASKIGADMLALSYFYSFNLPV 168

Query: 584 TSVIPCNVFGPHDN 625
               P N +GP  +
Sbjct: 169 IVARPFNAYGPRQS 182


>UniRef50_Q7WNH4 Cluster: Putative NAD dependent
           epimerase/dehydratase; n=1; Bordetella
           bronchiseptica|Rep: Putative NAD dependent
           epimerase/dehydratase - Bordetella bronchiseptica
           (Alcaligenes bronchisepticus)
          Length = 335

 Score = 37.9 bits (84), Expect = 0.29
 Identities = 21/65 (32%), Positives = 32/65 (49%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GD+RD  +  A+FA+H  T V+H AA+  GL    A        N+     +L A     
Sbjct: 55  GDVRDGARLRAVFAQHGITDVVHGAAITAGLERERAQPHAVIEVNLLGTLEVLAAAASCG 114

Query: 404 VKKVV 418
           +++VV
Sbjct: 115 IRRVV 119


>UniRef50_Q1FJC1 Cluster: DTDP-glucose 4,6-dehydratase; n=1;
           Clostridium phytofermentans ISDg|Rep: DTDP-glucose
           4,6-dehydratase - Clostridium phytofermentans ISDg
          Length = 330

 Score = 37.9 bits (84), Expect = 0.29
 Identities = 30/136 (22%), Positives = 60/136 (44%), Gaps = 2/136 (1%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GD+ DK     +F +     V+HLAA    +  ++  +++FF+ N+     + Q  H   
Sbjct: 60  GDILDKELLTTIFKEEGIDFVVHLAA-ESHVDRSLQSDIEFFQTNVIGTRMLYQVIHNVW 118

Query: 404 VKKVVSCLSTCIFPDKTTYPIDET--MVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577
              +       +  D+    ++E+   + + P H +N  YS +K   +++   Y ++YG 
Sbjct: 119 KDDISDKRILHVSTDEVYGELEESGQFIEHMPLHPNN-PYSASKAGGEMVAIAYRKTYGL 177

Query: 578 MFTSVIPCNVFGPHDN 625
                   N FGP+ +
Sbjct: 178 PIVRTRCSNNFGPYQH 193


>UniRef50_Q11WU7 Cluster: UDP-galactose-4-epimerase; n=1; Cytophaga
           hutchinsonii ATCC 33406|Rep: UDP-galactose-4-epimerase -
           Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
          Length = 319

 Score = 37.9 bits (84), Expect = 0.29
 Identities = 35/156 (22%), Positives = 67/156 (42%)
 Frame = +2

Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400
           +GD+R+    E +    +   VI   A +G +  ++   +     N+  + N+  A  + 
Sbjct: 57  EGDIRNY---EDVVKAVEGIEVISHQAALGSVPRSLKDPMTSNNANVLGSMNVFHAAKES 113

Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580
              +VV   S+ ++ D    P +E  + N         Y+ +KR I++  + ++  Y   
Sbjct: 114 GADRVVYASSSSVYGDDPGSPKEEDRLGNVLSP-----YAASKRSIELYAKAFSNVYPFR 168

Query: 581 FTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQ 688
           F ++   NVFGP  N     + VIP  I  + +  Q
Sbjct: 169 FIAMRYFNVFGPRQNAQGAYAAVIPQFITALLNGQQ 204


>UniRef50_A1GFD2 Cluster: NAD-dependent epimerase/dehydratase; n=4;
           Actinomycetales|Rep: NAD-dependent epimerase/dehydratase
           - Salinispora arenicola CNS205
          Length = 332

 Score = 37.9 bits (84), Expect = 0.29
 Identities = 39/149 (26%), Positives = 63/149 (42%), Gaps = 1/149 (0%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GD+RD  +   + A      V HLAA+VG +   +   LD    N+    N L+A  +  
Sbjct: 55  GDVRDAERL--ITAAEGVDEVYHLAAVVG-VDRYLRRPLDVVEVNVGGTHNALRAARRAG 111

Query: 404 VKKVVSCLSTCIFPD-KTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580
            + VVS  S     + +  +  D+  V  G   +  + YS +K   + L   Y+   G  
Sbjct: 112 ARIVVSSTSEVYGRNPRVPWREDDDRVL-GSTATDRWSYSTSKAAAEHLAFAYHRQEGLP 170

Query: 581 FTSVIPCNVFGPHDNFSLKSSHVIPALIR 667
            T +   NV+GP    +   S  I  ++R
Sbjct: 171 VTVLRYFNVYGPRQRPAYVLSRSIVRMLR 199


>UniRef50_Q5UXR0 Cluster: UDP-glucose 4-epimerase; n=3;
           Halobacteriaceae|Rep: UDP-glucose 4-epimerase -
           Haloarcula marismortui (Halobacterium marismortui)
          Length = 310

 Score = 37.9 bits (84), Expect = 0.29
 Identities = 40/145 (27%), Positives = 63/145 (43%), Gaps = 2/145 (1%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GD+R+    E+  A      VIHLAA+ G    +   + + F  N    +N+L A  K  
Sbjct: 56  GDIREYGDVES--AMRGVDRVIHLAAITGASSTHERRD-ETFAINYDGTENVLTAAGKLG 112

Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583
           V  VV   S  ++   T+  IDET+     P   N  Y+  K   + L + Y E +    
Sbjct: 113 VDHVVFASSCNVYGRATSTDIDETV----DPDPIN-PYAETKLQSETLLQEYCEEFDMTG 167

Query: 584 TSVIPCNVFG--PHDNFSLKSSHVI 652
           T++     FG  P   F+L  ++ +
Sbjct: 168 TALRMATNFGHSPGIRFNLVVNYFV 192


>UniRef50_A6GG02 Cluster: Putative uncharacterized protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Putative
           uncharacterized protein - Plesiocystis pacifica SIR-1
          Length = 313

 Score = 37.5 bits (83), Expect = 0.39
 Identities = 37/147 (25%), Positives = 62/147 (42%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GD+R+    E   A      VIHLAA  G +  ++       R N+    N+L AC +  
Sbjct: 53  GDIRELACCE--HAVRDVDAVIHLAAR-GSVPRSIDDPQATMRTNVMGTTNVLDACRRAG 109

Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583
           V++VV   S+ I+      P  E       P S    Y+ +K   + + + ++  +G   
Sbjct: 110 VRRVVQSSSSSIYGVVPGLPRREQ--QRPDPRSP---YAASKLAAEHVAQAWHACWGVEV 164

Query: 584 TSVIPCNVFGPHDNFSLKSSHVIPALI 664
            ++   NV+GP        + V+P  I
Sbjct: 165 VTLRLFNVYGPRQRSDSSYAAVVPLFI 191


>UniRef50_Q8WUS8 Cluster: HSPC105 protein; n=21; Euteleostomi|Rep:
           HSPC105 protein - Homo sapiens (Human)
          Length = 383

 Score = 37.5 bits (83), Expect = 0.39
 Identities = 34/138 (24%), Positives = 60/138 (43%), Gaps = 7/138 (5%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRE-NMSINDNILQACHKY 400
           GD+R  +  E  F     T V H+A+   G+      N +  +E N+   DNILQ C + 
Sbjct: 56  GDIRHLSDVEKAFQDADVTCVFHIASY--GMSGREQLNRNLIKEVNVRGTDNILQVCQRR 113

Query: 401 NVKKVV-SCLSTCIFPDKTTYPIDETM----VHNGPPHSSNFGYSYAKRMIDVLNRGYNE 565
            V ++V +     IF  +     DE++    +H  P H S       +++++      + 
Sbjct: 114 RVPRLVYTSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDR 173

Query: 566 SYGCMFTSVI-PCNVFGP 616
             G + T  + P  ++GP
Sbjct: 174 GDGVLRTCALRPAGIYGP 191


>UniRef50_Q2FS05 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           cellular organisms|Rep: NAD-dependent
           epimerase/dehydratase - Methanospirillum hungatei
           (strain JF-1 / DSM 864)
          Length = 343

 Score = 37.5 bits (83), Expect = 0.39
 Identities = 40/168 (23%), Positives = 68/168 (40%), Gaps = 2/168 (1%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVG-GLFHNMAHNLDFFRENMSINDNILQACHKY 400
           G + D      LF K+K  +V HL A    GL H +      +  N+  + N++    K 
Sbjct: 58  GSVSDANLITELFTKYKFEYVYHLGAYAAEGLSHFIRR--FNYTNNLIGSINLINEAVKV 115

Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580
             K  V   S  ++       I+  M     PH  +  Y  +K  +++     +  +G  
Sbjct: 116 GTKCFVFTSSIAVYG-----AIEPPMTEEKTPHPED-PYGISKLAVELDLMAAHSMFGLN 169

Query: 581 FTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDP-TFXSDGE 721
           +    P NV+G + N S    +VI   ++++ +    G P T   DGE
Sbjct: 170 YVIFRPHNVYGEYQNLSDPYRNVIGIFMKQIFE----GQPMTIFGDGE 213


>UniRef50_Q982P5 Cluster: UDP-glucose 4-epimerase; n=1;
           Mesorhizobium loti|Rep: UDP-glucose 4-epimerase -
           Rhizobium loti (Mesorhizobium loti)
          Length = 310

 Score = 37.1 bits (82), Expect = 0.51
 Identities = 36/134 (26%), Positives = 59/134 (44%), Gaps = 2/134 (1%)
 Frame = +2

Query: 221 DGDLRDKTQ-TEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 397
           +GD RD    T+AL +     H++H +        +MA ++   R+++  +  +L AC +
Sbjct: 49  EGDFRDNLAVTKALQSHDTVIHLVH-STWPSTADADMAADI---RDSVIPSVELLDACVR 104

Query: 398 YNVKKVVSCLSTCIFPDKTTY-PIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574
             VK+++   S       T Y  +DE  +    P +    Y  +K MI+   R Y   YG
Sbjct: 105 SGVKRIIYFSS-----GGTVYGEVDEIPIREDSPTNPVGAYGVSKLMIEHYVRLYERKYG 159

Query: 575 CMFTSVIPCNVFGP 616
                V   N FGP
Sbjct: 160 LNSFIVRLANPFGP 173


>UniRef50_Q8ECF4 Cluster: DTDP-glucose 4,6-dehydratase; n=18;
           Gammaproteobacteria|Rep: DTDP-glucose 4,6-dehydratase -
           Shewanella oneidensis
          Length = 375

 Score = 37.1 bits (82), Expect = 0.51
 Identities = 35/148 (23%), Positives = 60/148 (40%), Gaps = 1/148 (0%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           D+ D+T+ E +F+ H+P  V+HLAA    +  ++  + DF + N+     +L+A   Y +
Sbjct: 58  DICDRTELERVFSLHQPDAVMHLAA-ESHVDRSITGSADFIQTNIVGTYTLLEAARHYWM 116

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAK-RMIDVLNRGYNESYGCMF 583
           +      S   F   +T  +   + H   P   N   S       D        S   +F
Sbjct: 117 QLNTERKSAFRFHHISTDEVYGDLPH---PDEINVECSMLNDECKDHSTLNIQHSTLPLF 173

Query: 584 TSVIPCNVFGPHDNFSLKSSHVIPALIR 667
           T   P     P+      S H++ A +R
Sbjct: 174 TETTPYTPSSPYSASKASSDHLVRAWLR 201


>UniRef50_Q1QD53 Cluster: NAD-dependent epimerase/dehydratase; n=3;
           Bacteria|Rep: NAD-dependent epimerase/dehydratase -
           Psychrobacter cryohalolentis (strain K5)
          Length = 333

 Score = 37.1 bits (82), Expect = 0.51
 Identities = 28/124 (22%), Positives = 54/124 (43%), Gaps = 2/124 (1%)
 Frame = +2

Query: 251 EALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN-VKKVVSCL 427
           E +    K + +   AA + G+ + +   +     NM    N L+A H+   V++ +   
Sbjct: 65  EKIIEAAKGSEIFIHAAAIAGIDNTVKSPVRTMTVNMIGTANALEAAHQAGTVQRFLEFS 124

Query: 428 STCIFPDKTTYPIDE-TMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCN 604
           ++ +F  +  Y +DE      G    + + Y+ +K   + L   YN  +G    +  P N
Sbjct: 125 TSEVFGSRA-YRVDELNSTTTGAVGEARWTYAVSKLAGEHLTHAYNREHGLPTVTFRPFN 183

Query: 605 VFGP 616
           V+GP
Sbjct: 184 VYGP 187


>UniRef50_Q0BRM8 Cluster: UDP-glucose 4-epimerase; n=2;
           Rhodospirillales|Rep: UDP-glucose 4-epimerase -
           Granulobacter bethesdensis (strain ATCC BAA-1260 /
           CGDNIH1)
          Length = 342

 Score = 37.1 bits (82), Expect = 0.51
 Identities = 33/150 (22%), Positives = 66/150 (44%), Gaps = 4/150 (2%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAA--MVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400
           DL D+T   A  A+ +   V+H AA  +VG    +M   + +  +N ++   ++ AC ++
Sbjct: 65  DLADETTLHATLAEGQWDGVMHFAARSLVG---ESMVDPMLYMNQNAALGFKLIAACVQH 121

Query: 401 NVKKVVSCLSTCIFPDKTTYPIDE-TMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577
            V + +   +  +F      PIDE   +  G P+  +      +R +   +R +   Y C
Sbjct: 122 KVPRFLLSSTAALFGHHDDTPIDENAAIQPGSPYGES--KLMIERALSWADRIHGLRYAC 179

Query: 578 M-FTSVIPCNVFGPHDNFSLKSSHVIPALI 664
           + + +    +  G         +H+IP +I
Sbjct: 180 LRYFNAAGADPQGRSGEDHDPETHLIPLVI 209


>UniRef50_A6GE58 Cluster: NAD-dependent epimerase/dehydratase family
           protein; n=1; Plesiocystis pacifica SIR-1|Rep:
           NAD-dependent epimerase/dehydratase family protein -
           Plesiocystis pacifica SIR-1
          Length = 360

 Score = 37.1 bits (82), Expect = 0.51
 Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 4/168 (2%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPT-HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           D+RD        A+     HV+H AA V  +   +A        N+    N+L+A     
Sbjct: 81  DVRDPEALRQACARFDGVEHVLHHAA-VASVPRTLAEPETAHSVNVDGMFNLLEAARACG 139

Query: 404 VKKVVSCLSTCIFPDKTTYPID--ETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577
            K VV   S+ ++ D    P    ++    G P S    Y+  KR+ +VL + ++ ++G 
Sbjct: 140 AKSVVHATSSAVYGDCPGAPETGAQSEAIIGRPLSP---YAGQKRIAEVLGQTWSTTHGM 196

Query: 578 MFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGD-PTFXSDG 718
               +   N+ GP  + +   + VIP  I    D + +G+ P    DG
Sbjct: 197 SVVGLRYFNIVGPRQDPNGAYAAVIPKWI----DTLARGEQPVIFGDG 240


>UniRef50_A4QBQ0 Cluster: Putative uncharacterized protein; n=1;
           Corynebacterium glutamicum R|Rep: Putative
           uncharacterized protein - Corynebacterium glutamicum
           (strain R)
          Length = 335

 Score = 37.1 bits (82), Expect = 0.51
 Identities = 20/83 (24%), Positives = 41/83 (49%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GD+RD+   +++ A+++P+  IH AA    +  ++     +   N+     +L A H   
Sbjct: 62  GDIRDRAFVDSVLAQYQPSAAIHFAAK-KAVGESVEQPTMYLNINIGGTATLLDALHHAG 120

Query: 404 VKKVVSCLSTCIFPDKTTYPIDE 472
           V+ +V   S  +  + T  P++E
Sbjct: 121 VRDIVFSSSCSVHGETTHSPLNE 143


>UniRef50_Q57664 Cluster: Putative UDP-glucose 4-epimerase; n=3;
           cellular organisms|Rep: Putative UDP-glucose 4-epimerase
           - Methanococcus jannaschii
          Length = 305

 Score = 37.1 bits (82), Expect = 0.51
 Identities = 44/168 (26%), Positives = 71/168 (42%), Gaps = 2/168 (1%)
 Frame = +2

Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRE-NMSINDNILQACHK 397
           + D+RDK   E +  K     VIH AA +     N   N  +  + N+    NIL+   K
Sbjct: 48  NADIRDKDLDEKINFKDVEV-VIHQAAQIN--VRNSVENPVYDGDINVLGTINILEMMRK 104

Query: 398 YNVKKVVSCLS-TCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574
           Y++ K+V   S   ++ +    P+DE   H   P S    Y  +K + +   + YN  YG
Sbjct: 105 YDIDKIVFASSGGAVYGEPNYLPVDEN--HPINPLSP---YGLSKYVGEEYIKLYNRLYG 159

Query: 575 CMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDG 718
             +  +   NV+G   +     + VI   I +M   ++   P    DG
Sbjct: 160 IEYAILRYSNVYGERQD-PKGEAGVISIFIDKM---LKNQSPIIFGDG 203


>UniRef50_Q7UXZ2 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=2;
           Planctomycetaceae|Rep: 3-beta-hydroxysteroid
           dehydrogenase - Rhodopirellula baltica
          Length = 339

 Score = 36.7 bits (81), Expect = 0.68
 Identities = 33/130 (25%), Positives = 60/130 (46%), Gaps = 1/130 (0%)
 Frame = +2

Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCI-FPDKTTY 460
           VIH AA V G++ +  H   +F  N+  + N+LQAC +  V +++   S  + F      
Sbjct: 67  VIHTAA-VAGVWGSWQH---YFDNNVVASRNVLQACQELGVSQLIYTSSPSVTFDGNDQR 122

Query: 461 PIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKS 640
            +DE   +   P +    Y + K + +      ++  G    S+ P  ++GP D      
Sbjct: 123 DVDEAEPY---PETWMCHYPHTKSIAEREILAADQPGGMRTVSLRPHLIWGPDD------ 173

Query: 641 SHVIPALIRR 670
            H+IP +++R
Sbjct: 174 PHLIPRVLQR 183


>UniRef50_A6Q4T4 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Nitratiruptor sp. SB155-2|Rep: NAD-dependent
           epimerase/dehydratase - Nitratiruptor sp. (strain
           SB155-2)
          Length = 294

 Score = 36.7 bits (81), Expect = 0.68
 Identities = 38/162 (23%), Positives = 69/162 (42%), Gaps = 5/162 (3%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC--HKY 400
           D+  K Q   +F K    ++IHLAA+    F   A  +  +  N     N+L A    ++
Sbjct: 44  DITKKEQIRQIFQKKSFDYIIHLAAI---SFVGYADQVKMYEVNAFGVQNLLSALEEQEW 100

Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580
             KKV+   S  ++  + T  + E +  N   H     Y+Y+K + + + + Y +    +
Sbjct: 101 TAKKVIITSSATVYGMQRTNKLHEKLCPNPNNH-----YAYSKYISEQIAKTYFDKIPII 155

Query: 581 FTSVIPCNVFGPHDNFSLKSSHVIPALIR---RMDDAMQKGD 697
            T   P N  G       +   ++P L+R   R D  ++ G+
Sbjct: 156 ITR--PFNYTG----CGQREEFIVPKLVRAFQRKDSIIEIGN 191


>UniRef50_A3ERM8 Cluster: UDP-glucose 4-epimerase; n=1;
           Leptospirillum sp. Group II UBA|Rep: UDP-glucose
           4-epimerase - Leptospirillum sp. Group II UBA
          Length = 323

 Score = 36.7 bits (81), Expect = 0.68
 Identities = 31/150 (20%), Positives = 69/150 (46%), Gaps = 3/150 (2%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GD+RD     +LF+ +    VIH AA +  +  ++   L ++  N++    IL+    + 
Sbjct: 50  GDIRDPRALTSLFSHYPIEAVIHFAAAI-EVGESVQDPLKYWDNNLNGTLRILETMRSFG 108

Query: 404 VKKVVSCLSTCIFPDKTTYPI-DETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580
           V+ ++   +  ++  K+  PI +E  +    P+      + A+R+++     +  S    
Sbjct: 109 VRNLILSSTAAVYSPKSDGPITEEDRIDPQNPYGET--KAAAERLVEACRHAFGVSSVIF 166

Query: 581 --FTSVIPCNVFGPHDNFSLKSSHVIPALI 664
             F +      +G   + ++  SH+IPA++
Sbjct: 167 RYFNAAALEPSYGLVSH-AIPRSHLIPAVL 195


>UniRef50_A6SIX9 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 348

 Score = 36.7 bits (81), Expect = 0.68
 Identities = 25/79 (31%), Positives = 36/79 (45%)
 Frame = +2

Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400
           DGD+       ++F   KP  VIH A+ V         N  F++ N+     +++AC K 
Sbjct: 58  DGDITSLESLLSIFNSIKPDVVIHTASPVA----ITGTNDLFYKVNVGGTKCVVEACQKT 113

Query: 401 NVKKVVSCLSTCIFPDKTT 457
            VK +V   S  I  D TT
Sbjct: 114 GVKALVFTSSASIISDNTT 132


>UniRef50_Q5V6W4 Cluster: UDP-glucose 4-epimerase; n=1; Haloarcula
           marismortui|Rep: UDP-glucose 4-epimerase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 309

 Score = 36.7 bits (81), Expect = 0.68
 Identities = 44/167 (26%), Positives = 68/167 (40%), Gaps = 1/167 (0%)
 Frame = +2

Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400
           +GD+RD+   +A  A      V H AAMV  +  ++   +D    N +   N+   C + 
Sbjct: 56  EGDVRDRETLDA--AIEGVDVVFHEAAMVS-VPESIEQPVDCHELNGTATVNVFD-CARR 111

Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580
              +VV   S  ++      PI E       P   N  Y + K + +   R Y E YG  
Sbjct: 112 QDTRVVFASSAAVYGVPDDVPIGEDA-----PTEPNSPYGFEKYLGEQYARFYTEEYGLP 166

Query: 581 FTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDP-TFXSDG 718
              +   NV+GP      + + VI   +R+     Q G+P T   DG
Sbjct: 167 TVPLRYFNVYGPR-GLDGEYAGVIGTFVRQ----AQAGEPLTVEGDG 208


>UniRef50_Q65D61 Cluster: Putative uncharacterized protein; n=1;
           Bacillus licheniformis ATCC 14580|Rep: Putative
           uncharacterized protein - Bacillus licheniformis (strain
           DSM 13 / ATCC 14580)
          Length = 331

 Score = 36.3 bits (80), Expect = 0.90
 Identities = 28/132 (21%), Positives = 55/132 (41%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GD+RD+   + +F       V+H AA    +     +    F EN++  + +L    +Y+
Sbjct: 50  GDIRDRHFLKQVFENEDIEAVMHFAA--SPISSKSKNVFTSFNENITGMETLLDVMKEYD 107

Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583
           V ++V   S  ++      P+ E      P H+    +   K M++ +     ++YG  +
Sbjct: 108 VGRIVFASSAAVYGSPEDLPVTEE-TEPEPVHA----HGKVKWMMEKMLMEAEKAYGLKY 162

Query: 584 TSVIPCNVFGPH 619
             +   N  G H
Sbjct: 163 VILRSFNACGAH 174


>UniRef50_A3Q712 Cluster: UDP-glucose 4-epimerase; n=6;
           Actinobacteria (class)|Rep: UDP-glucose 4-epimerase -
           Mycobacterium sp. (strain JLS)
          Length = 329

 Score = 36.3 bits (80), Expect = 0.90
 Identities = 35/131 (26%), Positives = 53/131 (40%), Gaps = 1/131 (0%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAM-VGGLFHNMAHNLDFFRENMSINDNILQACHKY 400
           G L D    E    +H+ T VIH+A     G+  ++   L  + +N+S    +LQA    
Sbjct: 50  GTLLDGALVEQALREHEVTGVIHIAGFKYAGV--SVQRPLHTYEQNVSAMVTLLQAMETV 107

Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580
            V K+V   S   F       +DE+      P +    Y   K + + L R    + G  
Sbjct: 108 GVDKIVFSSSAATFGTPDVDQVDES-----TPTAPESPYGETKLIGEWLLRDAGRASGLR 162

Query: 581 FTSVIPCNVFG 613
            TS+   NV G
Sbjct: 163 HTSLRYFNVVG 173


>UniRef50_Q2FKD1 Cluster: NAD-dependent epimerase/dehydratase family
           protein; n=13; Staphylococcus aureus|Rep: NAD-dependent
           epimerase/dehydratase family protein - Staphylococcus
           aureus (strain USA300)
          Length = 326

 Score = 35.9 bits (79), Expect = 1.2
 Identities = 43/168 (25%), Positives = 75/168 (44%), Gaps = 4/168 (2%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN- 403
           D+R+    E +   ++  +VIHLAA+V  +  ++   +     N+     +L+   KYN 
Sbjct: 56  DIREYDAVEQIMKTYQFDYVIHLAALV-SVAESVEKPILSQEINVVATLRLLEIIKKYNN 114

Query: 404 -VKKVVSCLSTCIFPDKTTYP-IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577
            +K+ +   S  ++ D    P  D++++    P++      Y +R    LN  Y   Y  
Sbjct: 115 HIKRFIFASSAAVYGDLPDLPKSDQSLILPLSPYA--IDKYYGER--TTLN--YCSLYNI 168

Query: 578 MFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDP-TFXSDG 718
               V   NVFGP  +   KS +    +I +M D+ +   P TF  DG
Sbjct: 169 PTAVVKFFNVFGPRQD--PKSQY--SGVISKMFDSFEHNKPFTFFGDG 212


>UniRef50_Q1GKR7 Cluster: UDP-glucose 4-epimerase; n=17;
           Bacteria|Rep: UDP-glucose 4-epimerase - Silicibacter sp.
           (strain TM1040)
          Length = 327

 Score = 35.9 bits (79), Expect = 1.2
 Identities = 33/160 (20%), Positives = 66/160 (41%), Gaps = 6/160 (3%)
 Frame = +2

Query: 206 FSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQ 385
           F   + GDL D+ + + +FA++KP  V+H AA+   +   M+    ++  N+  +  +++
Sbjct: 44  FGPFEQGDLTDRGRLDEVFAQYKPVAVMHFAAL-SQVGEAMSEPGRYWANNVGGSLCLIE 102

Query: 386 ACHKYNVKKVVSCLSTCIFPDKTTY-PIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYN 562
           A           CL         TY   D  ++    P      Y  +KR ++ + + + 
Sbjct: 103 AA------VAAGCLDFVFSSTCATYGEHDNVVLDENTPQQPLNAYGASKRAVEDILKDFE 156

Query: 563 ESYGCMFTSVIPCNVFGPH-----DNFSLKSSHVIPALIR 667
            ++G         NV G         F    +H++P +I+
Sbjct: 157 AAHGLRSVIFRYFNVAGADPEAEVGEFHQPETHLVPLMIQ 196


>UniRef50_P14169 Cluster: CDP-paratose 2-epimerase; n=12; cellular
           organisms|Rep: CDP-paratose 2-epimerase - Salmonella
           typhi
          Length = 338

 Score = 35.9 bits (79), Expect = 1.2
 Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 5/110 (4%)
 Frame = +2

Query: 161 DRQKRNSDYDSETWIFS-GSKD---GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNM 328
           D   R    D+  W+ S G+ +   GD+R+K     L  K+ P    HLA  V  +  ++
Sbjct: 31  DNLSRKGATDNLHWLSSLGNFEFVHGDIRNKNDVTRLITKYMPDSCFHLAGQV-AMTTSI 89

Query: 329 AHNLDFFRENMSINDNILQACHKYNVK-KVVSCLSTCIFPDKTTYPIDET 475
            +    F  N+    N+L+A  +YN    ++   +  ++ D   Y  +ET
Sbjct: 90  DNPCMDFEINVGGTLNLLEAVRQYNSNCNIIYSSTNKVYGDLEQYKYNET 139


>UniRef50_UPI0001597850 Cluster: hypothetical protein RBAM_031220;
           n=1; Bacillus amyloliquefaciens FZB42|Rep: hypothetical
           protein RBAM_031220 - Bacillus amyloliquefaciens FZB42
          Length = 309

 Score = 35.5 bits (78), Expect = 1.6
 Identities = 19/64 (29%), Positives = 32/64 (50%)
 Frame = +2

Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 463
           V+HLAAMV G+    ++  D  R N     N+ + C +  +  ++   S+ +F D   +P
Sbjct: 63  VVHLAAMV-GVDSCRSNEEDVIRVNFEGTKNVTEVCGELGISTLLFSSSSEVFGDSPDFP 121

Query: 464 IDET 475
             ET
Sbjct: 122 YTET 125


>UniRef50_Q97KX2 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=2; Clostridium|Rep: Nucleoside-diphosphate-sugar
           epimerase - Clostridium acetobutylicum
          Length = 315

 Score = 35.5 bits (78), Expect = 1.6
 Identities = 32/118 (27%), Positives = 53/118 (44%), Gaps = 1/118 (0%)
 Frame = +2

Query: 269 HKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPD 448
           +K  ++IHLAA+VG     M   ++  + + +  DN+L+A H YN K +    S+ I+  
Sbjct: 64  NKCDYIIHLAAVVGVRLA-MLKGIEGLKVSCTGTDNMLEAAHLYN-KGIFISSSSAIYGK 121

Query: 449 KTTYPIDETMVH-NGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPH 619
            +   +DE      G     ++ YS  K   + L   Y+   G         NV GP+
Sbjct: 122 ISKKSVDEEDDSVLGTSKKPSWLYSVGKLTEEHLVLAYHRELGVKVKIGRFFNVIGPY 179


>UniRef50_Q8RGC6 Cluster: UDP-glucose 4-epimerase; n=2;
           Fusobacterium nucleatum|Rep: UDP-glucose 4-epimerase -
           Fusobacterium nucleatum subsp. nucleatum
          Length = 324

 Score = 35.5 bits (78), Expect = 1.6
 Identities = 29/138 (21%), Positives = 65/138 (47%), Gaps = 1/138 (0%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           G+++D      +F ++K   V+H A  +  +  ++     ++  N      ++Q+  K+N
Sbjct: 51  GNVQDYELMSRIFQENKIEAVMHFAGYIR-VPESVDDPNKYYLNNTYTTMCLIQSMVKHN 109

Query: 404 VKKVVSCLSTCIFPDKTT-YPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580
           +K ++   +  ++ + T   PIDE   H+  P +    Y  +K M + + R   ++YG  
Sbjct: 110 IKNIIFSSTAAVYGEITEDNPIDEK--HSTIPINP---YGASKLMSERIIRDCAKAYGLN 164

Query: 581 FTSVIPCNVFGPHDNFSL 634
           ++     NV G H+ + +
Sbjct: 165 YSIFRYFNVAGAHEKYPI 182


>UniRef50_A7DIX5 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Methylobacterium extorquens PA1|Rep: NAD-dependent
           epimerase/dehydratase - Methylobacterium extorquens PA1
          Length = 323

 Score = 35.5 bits (78), Expect = 1.6
 Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 2/116 (1%)
 Frame = +2

Query: 377 ILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSY--AKRMIDVLN 550
           + +AC +  V  +V   S  ++      P DET +    P S N  YSY  +K + +++ 
Sbjct: 102 VSEACIEAGVPDLVVASSAEVYQTPRVVPTDET-IEMVIPDSLNPRYSYGGSKLISELIA 160

Query: 551 RGYNESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDG 718
             Y            P N++GP   +     HV+P LI ++  A   G  T   DG
Sbjct: 161 FNYCRDKLRKVQVFRPHNIYGPDMGWK----HVVPQLIEKIVAAGDGGSITLQGDG 212


>UniRef50_A6PTX1 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Victivallis vadensis ATCC BAA-548|Rep: NAD-dependent
           epimerase/dehydratase - Victivallis vadensis ATCC
           BAA-548
          Length = 305

 Score = 35.5 bits (78), Expect = 1.6
 Identities = 45/186 (24%), Positives = 75/186 (40%)
 Frame = +2

Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400
           +GD+RD+       A     +V HLAAM+  +  +M   ++    N +    +L+   K 
Sbjct: 49  EGDIRDRITVAK--AMEDVDYVFHLAAMIS-VPESMTKIIECIDINNTGMLIVLEEAAKA 105

Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580
            VKK+    S  I+ D    P  ETM     P S    Y+  K   +   + +N++    
Sbjct: 106 GVKKLCFSTSAAIYGDNPVVPKVETMFPE--PKSP---YAITKLDGEYYCKMFNDTGKLK 160

Query: 581 FTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXI 760
              +   NVFGP  +     +  +P    +   A+     T   DGE     D +++  I
Sbjct: 161 TACLRYFNVFGPRQDPKSAYAAAVPIFTAK---AVANEPLTIFGDGEQTR--DFIYVKDI 215

Query: 761 SASCSF 778
            A+  F
Sbjct: 216 VAANVF 221


>UniRef50_A6BZU3 Cluster: Putative uncharacterized protein; n=1;
           Planctomyces maris DSM 8797|Rep: Putative
           uncharacterized protein - Planctomyces maris DSM 8797
          Length = 324

 Score = 35.5 bits (78), Expect = 1.6
 Identities = 37/144 (25%), Positives = 61/144 (42%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GDLRD    E   A  +   V H AA+   +  ++ H LD     ++   ++L A  +  
Sbjct: 54  GDLRDLAAVEQATAGVEI--VFHQAALAS-VPRSVEHPLDTHEACVTGTVHVLDAARRSG 110

Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583
           V++VV   S+  + ++   P      H G        Y+ AK   ++  + +  SY    
Sbjct: 111 VQRVVYAGSSSAYGNQEQMP-----KHEGQTPEVLSPYAAAKLAGELYCQAFANSYDLET 165

Query: 584 TSVIPCNVFGPHDNFSLKSSHVIP 655
             +   NVFGP  + +   S VIP
Sbjct: 166 VRIRYFNVFGPRQDPNSPYSAVIP 189


>UniRef50_A3H6D1 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Caldivirga maquilingensis IC-167|Rep: NAD-dependent
           epimerase/dehydratase - Caldivirga maquilingensis IC-167
          Length = 326

 Score = 35.5 bits (78), Expect = 1.6
 Identities = 26/118 (22%), Positives = 52/118 (44%)
 Frame = +2

Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400
           + DL D  +  ++  +     +IHLAAM+  L  +    L   + N+    N+ +A    
Sbjct: 52  NADLSDFDELISIIKRFNVRRIIHLAAMI--LLESRNRPLKAAKVNIIGTLNVFEAARLM 109

Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574
           ++++VV   S  ++     Y    ++  +  PH+    Y   K   ++    Y+E+YG
Sbjct: 110 DLERVVYASSESVYGSPLVYG-KGSVNEDDYPHTPPDPYHITKLADELFGSYYSEAYG 166


>UniRef50_Q8KNN2 Cluster: DTDP-D-glucose-4,6-dehydratase; n=4;
           Bacteria|Rep: DTDP-D-glucose-4,6-dehydratase - Aeromonas
           hydrophila
          Length = 379

 Score = 35.1 bits (77), Expect = 2.1
 Identities = 37/146 (25%), Positives = 66/146 (45%), Gaps = 15/146 (10%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY-- 400
           D+ ++ + + +FA+H+P  V+HLAA    +  ++    DF   N+     +L+A   Y  
Sbjct: 76  DICNRAELDRVFAQHQPDAVMHLAA-ESHVDRSITGPADFIETNIVGTYMLLEAARAYWN 134

Query: 401 ---NVKKVV---SCLST------CIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDV 544
               V+K       +ST         PD+    +   +     P++ +  YS +K   D 
Sbjct: 135 GLDEVRKAAFRFHHISTDEVYGDLPHPDEVAPGVALPLFTETTPYAPSSPYSASKASSDH 194

Query: 545 LNRGYNESYGCMFTSVIPC-NVFGPH 619
           L R +  +YG + T V  C N +GP+
Sbjct: 195 LVRAWRRTYG-LPTIVTNCSNNYGPY 219


>UniRef50_A7HN54 Cluster: Polysaccharide biosynthesis protein CapD;
           n=2; Thermotogaceae|Rep: Polysaccharide biosynthesis
           protein CapD - Fervidobacterium nodosum Rt17-B1
          Length = 606

 Score = 35.1 bits (77), Expect = 2.1
 Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNL-DFFRENMSINDNILQACHKYN 403
           D+ DK   E +F  H+P  V H AA     F  M +NL +  R N+    N+ +    YN
Sbjct: 341 DVTDKNMMEKIFKTHRPDIVFHAAAHKHVFF--MQNNLYEALRVNVLGTINLAKLSCNYN 398

Query: 404 VKKVVSCLSTCIFPDKTTYP 463
           V+K V  +ST    DK  +P
Sbjct: 399 VEKFV-FIST----DKAVHP 413


>UniRef50_A6CEQ2 Cluster: Putative uncharacterized protein; n=1;
           Planctomyces maris DSM 8797|Rep: Putative
           uncharacterized protein - Planctomyces maris DSM 8797
          Length = 333

 Score = 34.7 bits (76), Expect = 2.7
 Identities = 40/151 (26%), Positives = 66/151 (43%), Gaps = 2/151 (1%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GD+RD T  E   A      V H AA V G++ +  +   F+  N     N++ +C    
Sbjct: 48  GDIRDATTVER--ACEGIETVYHTAA-VSGIWGHWDY---FYSINTRGTLNVIASCQSQG 101

Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNF--GYSYAKRMIDVLNRGYNESYGC 577
           V ++V   S  +  D + +   E    +  P+S +F   Y + K + +      N   G 
Sbjct: 102 VTRLVYTSSPSVVYDGSAH---ENATES-LPYSEHFLCHYPHTKMLAERAVLQANGENGL 157

Query: 578 MFTSVIPCNVFGPHDNFSLKSSHVIPALIRR 670
              ++ P  ++GP DN      H+IP LI+R
Sbjct: 158 ATVALRPHLIWGPRDN------HLIPRLIQR 182


>UniRef50_A0LGE9 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: NAD-dependent
           epimerase/dehydratase - Syntrophobacter fumaroxidans
           (strain DSM 10017 / MPOB)
          Length = 315

 Score = 34.7 bits (76), Expect = 2.7
 Identities = 23/85 (27%), Positives = 38/85 (44%)
 Frame = +2

Query: 515 YSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKG 694
           Y  AK M++     ++  YG  +  V P N FGP  N+ +    VIP   R++ D     
Sbjct: 144 YGVAKLMMEKYLYMFSYLYGLEYIIVRPSNPFGPRQNY-MGEQGVIPIFFRKILD----- 197

Query: 695 DPTFXSDGEAXNHSDSLFIHXISAS 769
           D T    G+     D L++  ++ +
Sbjct: 198 DETISIWGDGKGTKDYLYVEDLAGA 222


>UniRef50_Q8ZW82 Cluster: UDP-glucose 4-epimerase; n=6;
           Thermoprotei|Rep: UDP-glucose 4-epimerase - Pyrobaculum
           aerophilum
          Length = 314

 Score = 34.7 bits (76), Expect = 2.7
 Identities = 23/90 (25%), Positives = 37/90 (41%)
 Frame = +2

Query: 347 FRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYA 526
           F EN+    N+L+   +  VK V+   S+ ++ D    P  E       P+     Y  A
Sbjct: 86  FNENVLATFNVLEWARQTGVKSVIFASSSTVYGDAEVIPTPEE-----APYKPISVYGAA 140

Query: 527 KRMIDVLNRGYNESYGCMFTSVIPCNVFGP 616
           K   +V+   Y   YG    ++   N+ GP
Sbjct: 141 KAAGEVMCATYARLYGVKCLAIRYANIIGP 170


>UniRef50_P18645 Cluster: UDP-glucose 4-epimerase; n=353; cellular
           organisms|Rep: UDP-glucose 4-epimerase - Rattus
           norvegicus (Rat)
          Length = 347

 Score = 34.7 bits (76), Expect = 2.7
 Identities = 24/91 (26%), Positives = 42/91 (46%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           D+ D+   + LF KH    VIH A +   +  ++   LD++R N++    +L+      V
Sbjct: 66  DILDQAALQHLFKKHNFKAVIHFAGL-KAVGESVQKPLDYYRVNLTGTIQLLEIMRAMGV 124

Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPH 499
           K +V   S  ++      P+  +    GPPH
Sbjct: 125 KSLVFSSSATVYGK----PVPAS--GRGPPH 149


>UniRef50_Q7CS52 Cluster: AGR_L_3011p; n=3; Alphaproteobacteria|Rep:
           AGR_L_3011p - Agrobacterium tumefaciens (strain C58 /
           ATCC 33970)
          Length = 356

 Score = 34.3 bits (75), Expect = 3.6
 Identities = 32/142 (22%), Positives = 56/142 (39%)
 Frame = +2

Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400
           +GD+ D    +A   +  P  VIH AA    +  ++     ++R N+  + ++L AC   
Sbjct: 79  EGDILDGVLLKATLREFSPAFVIHCAAN-AYVGESVEDPRKYYRNNVGGSLSLLDACLDQ 137

Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580
           N+  +V   S   +      PI E      P +     Y   K + ++    Y  +YG  
Sbjct: 138 NIGGLVFSSSCATYGVPQQLPIREETAQM-PVNP----YGRTKLIFEMALEDYAAAYGLR 192

Query: 581 FTSVIPCNVFGPHDNFSLKSSH 646
           F ++   N  G   +  L   H
Sbjct: 193 FVALRYFNAAGADPDGELYERH 214


>UniRef50_Q1YQ08 Cluster: Oxidoreductase; n=1; gamma proteobacterium
           HTCC2207|Rep: Oxidoreductase - gamma proteobacterium
           HTCC2207
          Length = 336

 Score = 34.3 bits (75), Expect = 3.6
 Identities = 26/111 (23%), Positives = 45/111 (40%)
 Frame = +2

Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 463
           +IH AA+V     N   + D +R N+    N++ A  KYNV++ V   S   + +     
Sbjct: 76  IIHTAALVS----NALSDADMWRVNVQATANLIAAAEKYNVRRFVQLSSIVAYGNSAAGE 131

Query: 464 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGP 616
           + E    + P H+    Y   K   +      +         + P +V+GP
Sbjct: 132 LCE----DHPVHADGGSYVLTKLASEHAVLAAHAKGNIEIVIIRPGDVYGP 178


>UniRef50_A7I3Y2 Cluster: Putative zinc protease; n=1; Campylobacter
           hominis ATCC BAA-381|Rep: Putative zinc protease -
           Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 /
           NCTC 13146 /CH001A)
          Length = 915

 Score = 34.3 bits (75), Expect = 3.6
 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 8/79 (10%)
 Frame = +2

Query: 260 FAKHKPTHVIHLAAMVG-----GLFHNMAHNLDFFRENMSINDNILQACHKYN---VKKV 415
           F+  + T +  LA M+      G F+N   N+    EN S+N ++   C +YN    KK 
Sbjct: 537 FSNFENTKIARLAVMISNESGLGGFNNYETNIITANENFSLNKSLNDICVEYNSLSSKKD 596

Query: 416 VSCLSTCIFPDKTTYPIDE 472
           VS     IF D     IDE
Sbjct: 597 VSNALKAIFADIKNAKIDE 615


>UniRef50_A4BBD6 Cluster: Putative uncharacterized protein; n=1;
           Reinekea sp. MED297|Rep: Putative uncharacterized
           protein - Reinekea sp. MED297
          Length = 314

 Score = 34.3 bits (75), Expect = 3.6
 Identities = 29/118 (24%), Positives = 57/118 (48%), Gaps = 3/118 (2%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           D+ D+T  + L  +H+ THV+HLA+++     + A +   +R ++    N+++AC    V
Sbjct: 49  DINDETLAD-LMREHRITHVVHLASVLEA-SEDRARD---YRIDVDGTRNVIEACLAAGV 103

Query: 407 KKVVSCLSTCIFPDKTTYPIDET-MVHNGPPHSSN--FGYSYAKRMIDVLNRGYNESY 571
           + +    S   +     Y  D    +    P   N  F YS+ KR+++ +   Y +S+
Sbjct: 104 EHLTVSSSGAAY----GYHADNAEWLSEADPLRGNYEFAYSWHKRLVEDMLAEYRQSH 157


>UniRef50_A1IBU5 Cluster: Nucleoside-diphosphate-sugar
           epimerases-like; n=1; Candidatus Desulfococcus
           oleovorans Hxd3|Rep: Nucleoside-diphosphate-sugar
           epimerases-like - Candidatus Desulfococcus oleovorans
           Hxd3
          Length = 589

 Score = 34.3 bits (75), Expect = 3.6
 Identities = 32/121 (26%), Positives = 57/121 (47%), Gaps = 3/121 (2%)
 Frame = +2

Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 463
           V HLA +VG +  +    LD    N++ + N+ ++C K NV KV+   S+ ++      P
Sbjct: 68  VYHLAFIVGQI-QDTQKALDI---NINGSRNVFESCVKNNVSKVIYTSSSTVYGAHADNP 123

Query: 464 IDETMVHNGPPH-SSNFGYSYAKRMIDVLNRGYNESY-GCMFTSVIPCNVFGPH-DNFSL 634
           I      + P   + +  Y+ +K  ++   R +  ++    FT +    +FGPH DN   
Sbjct: 124 IG--FREDAPLRVNEDSYYNESKVKVETFARDFFRNHPDITFTVIRSALLFGPHIDNMFS 181

Query: 635 K 637
           K
Sbjct: 182 K 182


>UniRef50_Q868I5 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=2;
           Giardia intestinalis|Rep: UDP-N-acetylglucosamine
           4-epimerase - Giardia lamblia (Giardia intestinalis)
          Length = 385

 Score = 34.3 bits (75), Expect = 3.6
 Identities = 36/151 (23%), Positives = 64/151 (42%), Gaps = 2/151 (1%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAK--HKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 397
           GD+RDK    A+F++   K   VIHLAA V  +  ++ +   +   N+  + N+ Q    
Sbjct: 63  GDIRDK----AIFSRLPQKIDFVIHLAAAVS-VAESVTNPQKYMLTNVEGSRNVFQYAVD 117

Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577
                V+S  +   + D     I E       P+     Y+ +K  ++ L   + ++  C
Sbjct: 118 AKASAVLSASTAAYYGDCGKSAITEAF-----PYGGISPYAESKMEMERLGAEFQKTSRC 172

Query: 578 MFTSVIPCNVFGPHDNFSLKSSHVIPALIRR 670
            F      NV+GP  + S   + V+   + R
Sbjct: 173 RFIFCRFFNVYGPRQDPSSPYTGVMSIFMDR 203


>UniRef50_Q54WS6 Cluster: Putative dTDP-D-glucose 4,6-dehydratase;
           n=1; Dictyostelium discoideum AX4|Rep: Putative
           dTDP-D-glucose 4,6-dehydratase - Dictyostelium
           discoideum AX4
          Length = 434

 Score = 34.3 bits (75), Expect = 3.6
 Identities = 19/65 (29%), Positives = 32/65 (49%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           G++ D    E +F K K   VIHLAA    + ++   ++ F   N+     +L+ C  Y 
Sbjct: 67  GNILDSELLENIFEKEKIDIVIHLAAYT-HVDNSFKQSIKFTENNILGTHYLLETCKNYK 125

Query: 404 VKKVV 418
           +KK +
Sbjct: 126 LKKFI 130


>UniRef50_A0BCG5 Cluster: Chromosome undetermined scaffold_10, whole
           genome shotgun sequence; n=8; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_10,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 1051

 Score = 34.3 bits (75), Expect = 3.6
 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
 Frame = +2

Query: 293 LAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCI--FPDKTTYPI 466
           L AM  G F  ++  LD F  +    DNI+    K+N K + S   T I  +PD+ T   
Sbjct: 96  LQAMTSGNFPPLSKLLDNFHASEIKEDNIMFQMKKFNKKTLFSGDDTWIGLYPDQFTLQF 155

Query: 467 DETMVHNGPPHSSNFGYSYAKRMIDVLNRGYN 562
            +   + G  HS +       ++++ L++GY+
Sbjct: 156 PQKSFNIGDMHSVD--QFNCDKILENLDKGYD 185


>UniRef50_A3LR65 Cluster: Putative dtdp-glucose 4,6-dehydratase;
           n=1; Pichia stipitis|Rep: Putative dtdp-glucose
           4,6-dehydratase - Pichia stipitis (Yeast)
          Length = 332

 Score = 34.3 bits (75), Expect = 3.6
 Identities = 34/141 (24%), Positives = 64/141 (45%), Gaps = 3/141 (2%)
 Frame = +2

Query: 260 FAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCI 439
           F  ++ T +++ AA    +  + +  L F R N+ +  N+L+ C +  +K+  S +S  +
Sbjct: 83  FPINQITDIVNFAAE-SSVDKSFSDPLYFTRNNILVTQNLLE-CMRL-LKQQNSQISVRL 139

Query: 440 FPDKTTYPIDETMVHN---GPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVF 610
               T     ++ + N   G    +N  Y+  K  ID++   Y  SY    T + P N++
Sbjct: 140 LHISTDEVYGDSDILNDEQGRLLPTN-PYAATKASIDLIIHSYQCSYDLSVTIIRPNNIY 198

Query: 611 GPHDNFSLKSSHVIPALIRRM 673
           GPH         ++P  I R+
Sbjct: 199 GPHQ----YPDKIVPVTIERL 215


>UniRef50_Q59083 Cluster: UDP-glucose 4-epimerase; n=14;
           Bacteria|Rep: UDP-glucose 4-epimerase - Azospirillum
           brasilense
          Length = 348

 Score = 34.3 bits (75), Expect = 3.6
 Identities = 19/84 (22%), Positives = 40/84 (47%)
 Frame = +2

Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400
           +GD+      + +   H+   V+H A  +  +  ++   LD++R N + +  +L AC + 
Sbjct: 57  EGDIGSAELLDRVMRDHRVDAVMHFAGSIV-VPESVVKPLDYYRNNTANSLTLLGACLRA 115

Query: 401 NVKKVVSCLSTCIFPDKTTYPIDE 472
            + KVV   +  ++    + PI E
Sbjct: 116 GIDKVVFSSTAAVYGAPESVPIRE 139


>UniRef50_Q2JCE7 Cluster: DTDP-glucose 4,6-dehydratase; n=5;
           Bacteria|Rep: DTDP-glucose 4,6-dehydratase - Frankia sp.
           (strain CcI3)
          Length = 357

 Score = 33.9 bits (74), Expect = 4.8
 Identities = 38/150 (25%), Positives = 60/150 (40%), Gaps = 1/150 (0%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GD+RD+   E++  +H    V++ AA        +    +FF  N+     +L+A     
Sbjct: 80  GDIRDQELVESVLREHSVDVVVNFAAESHNSLAIIRPG-EFFATNVMGTQTLLEAARTVG 138

Query: 404 VKKVVSCLSTC-IFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580
           V +    +STC ++ D      D        P+     Y+ AK   D   R Y  +Y   
Sbjct: 139 VARFHQ-ISTCEVYGDMDLN--DPGAFTEDSPYLPRTPYNAAKAGGDHAVRAYGFTYNLP 195

Query: 581 FTSVIPCNVFGPHDNFSLKSSHVIPALIRR 670
            T     N +GP+  F  K   VIP  + R
Sbjct: 196 VTITNCSNNYGPY-QFPEK---VIPLFVTR 221


>UniRef50_Q01T66 Cluster: DTDP-glucose 4,6-dehydratase precursor;
           n=2; Bacteria|Rep: DTDP-glucose 4,6-dehydratase
           precursor - Solibacter usitatus (strain Ellin6076)
          Length = 339

 Score = 33.9 bits (74), Expect = 4.8
 Identities = 32/133 (24%), Positives = 55/133 (41%), Gaps = 1/133 (0%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GD+ D    EA  A+ +P  ++H AA    +  ++       R N +    +L+A  +  
Sbjct: 57  GDICDAALVEATLAEERPDAIVHFAA-ESHVDRSILSPEPVVRTNYNGTFTLLEAARRQK 115

Query: 404 VKKVVSCLSTCIFPD-KTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580
           + + V   +  ++   +     DE  V N  P S    YS +K   D+L R Y  +Y   
Sbjct: 116 IARFVHVSTDEVYGSLEAPAEADEAYVLN--PSSP---YSASKAASDLLARSYFVTYKLP 170

Query: 581 FTSVIPCNVFGPH 619
                  N +GP+
Sbjct: 171 VLITRASNNYGPY 183


>UniRef50_A7HHX8 Cluster: NAD-dependent epimerase/dehydratase; n=4;
           Cystobacterineae|Rep: NAD-dependent
           epimerase/dehydratase - Anaeromyxobacter sp. Fw109-5
          Length = 317

 Score = 33.9 bits (74), Expect = 4.8
 Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 5/135 (3%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAH-NLDFFRENMSINDNILQACHKYN 403
           DLR K + E +F +H+P  +IH+     G+ H+      +    N+     IL  C ++ 
Sbjct: 61  DLR-KARVEEVFRRHRPEALIHM-----GIMHDPRDPRSEAHSFNVLGTHKILDLCVRHG 114

Query: 404 VKKVVSCLSTCIF---PDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574
           VKK V   S  ++   PD + +  +ET +  G      F        +D+  + +   + 
Sbjct: 115 VKKAVVLSSANVYGPRPDNSNFLPEETPLMAG----ERFSEMRDLIELDMYAQSFMWKHP 170

Query: 575 CMFTSVI-PCNVFGP 616
            + T V+ P N+ GP
Sbjct: 171 ELETVVLRPVNIIGP 185


>UniRef50_A6H035 Cluster: GDP-4-dehydro-D-rhamnose reductase; n=1;
           Flavobacterium psychrophilum JIP02/86|Rep:
           GDP-4-dehydro-D-rhamnose reductase - Flavobacterium
           psychrophilum (strain JIP02/86 / ATCC 49511)
          Length = 297

 Score = 33.9 bits (74), Expect = 4.8
 Identities = 30/136 (22%), Positives = 64/136 (47%), Gaps = 3/136 (2%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC---HK 397
           +L +K +  A+  + +P+ VIHLAA +  + H   +  + +  N+    N+L+A     K
Sbjct: 50  NLLEKEKLSAIIKEIQPSIVIHLAA-ISFVGHENLN--EMYDVNVIGTQNLLEAIKNESK 106

Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577
            +++K++   S  ++ ++T   + E +  N   H     Y  +K  ++ + + Y ++   
Sbjct: 107 DSIRKIIIASSATVYGNQTETVLSEALCPNPVNH-----YGISKLAMEFVAKTYFDTLPI 161

Query: 578 MFTSVIPCNVFGPHDN 625
           + T   P N   P  N
Sbjct: 162 IITR--PFNYTAPEQN 175


>UniRef50_A3DIS0 Cluster: Polysaccharide biosynthesis protein CapD
           precursor; n=1; Clostridium thermocellum ATCC 27405|Rep:
           Polysaccharide biosynthesis protein CapD precursor -
           Clostridium thermocellum (strain ATCC 27405 / DSM 1237)
          Length = 607

 Score = 33.9 bits (74), Expect = 4.8
 Identities = 19/65 (29%), Positives = 33/65 (50%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           G +RDK + + +F+++KP  V H AA          +  +  + N+    N+ +  H+YN
Sbjct: 338 GSIRDKKRLDYVFSQYKPGIVFHAAAHKHVPLMEF-NPQEAVKNNVFGTLNVAECAHQYN 396

Query: 404 VKKVV 418
            KK V
Sbjct: 397 CKKFV 401


>UniRef50_A3CKR6 Cluster: Nucleoside-diphosphate-sugar epimerase,
           putative; n=2; Streptococcus|Rep:
           Nucleoside-diphosphate-sugar epimerase, putative -
           Streptococcus sanguinis (strain SK36)
          Length = 350

 Score = 33.9 bits (74), Expect = 4.8
 Identities = 25/124 (20%), Positives = 54/124 (43%), Gaps = 1/124 (0%)
 Frame = +2

Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 463
           + H AA     +    H  + +  N+   +N+L+A ++  +++ V   S  +   +    
Sbjct: 83  LFHTAAFFRDNYKGGKHWQELYDTNIIGTNNLLEAAYEAGIRQFVHTSSCVVLEGEANQL 142

Query: 464 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF-TSVIPCNVFGPHDNFSLKS 640
           IDE+M  +     + F Y  +K + +   R + + +  +F   ++P  + GP D     S
Sbjct: 143 IDESMSRS---KDTPFDYYRSKILSEEAVRDFLDKHSDVFGCFILPSVMLGPRDLGPTSS 199

Query: 641 SHVI 652
             +I
Sbjct: 200 GQMI 203


>UniRef50_A0UVI4 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Clostridium cellulolyticum H10|Rep: NAD-dependent
           epimerase/dehydratase - Clostridium cellulolyticum H10
          Length = 309

 Score = 33.9 bits (74), Expect = 4.8
 Identities = 40/171 (23%), Positives = 70/171 (40%), Gaps = 4/171 (2%)
 Frame = +2

Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSIN----DNILQA 388
           +GD+RD  + E +        V H AA V     ++ ++    +E M IN     NIL+ 
Sbjct: 50  EGDIRDSKKIEEVL--EGVDVVFHNAAFV-----SIRNSYTMLKEEMDINCYGTQNILEG 102

Query: 389 CHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNES 568
             K  V+K+V   S   +      PI E    +  P S    Y ++K   ++  + + + 
Sbjct: 103 MVKQRVRKIVFASSMAAYGWPRQIPITEDC--DLAPISP---YGFSKARCELYCKIFAKR 157

Query: 569 YGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGE 721
           +G  +  +  CN++G         S  +  L   ++ A+     T   DGE
Sbjct: 158 FGISYVILRYCNIYGIKQTL----SPYVGVLTTFINQALSSQPITVNGDGE 204


>UniRef50_A0L9M4 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Magnetococcus sp. MC-1|Rep: NAD-dependent
           epimerase/dehydratase - Magnetococcus sp. (strain MC-1)
          Length = 330

 Score = 33.9 bits (74), Expect = 4.8
 Identities = 23/71 (32%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRE-NMSINDNILQACHKYN 403
           D+RD+   +ALFA+ +   VIHLAA+VG      A   +  ++ N   + ++L+A  ++ 
Sbjct: 56  DIRDREAMQALFAQTQFHGVIHLAAIVGD--PACARQSELAQQTNWQASIDLLEASKQHG 113

Query: 404 VKKVVSCLSTC 436
           V++ +   STC
Sbjct: 114 VERFIFA-STC 123


>UniRef50_Q5DAK3 Cluster: SJCHGC01535 protein; n=2; Schistosoma
           japonicum|Rep: SJCHGC01535 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 249

 Score = 33.9 bits (74), Expect = 4.8
 Identities = 16/45 (35%), Positives = 30/45 (66%), Gaps = 2/45 (4%)
 Frame = +2

Query: 359 MSINDN--ILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHN 487
           +SIND+  I Q+ + Y++ K++S  S C+ P++T +   E +V+N
Sbjct: 141 LSINDSEVIDQSNYVYDIYKMISSQSNCLLPEETIWCSTEDLVNN 185


>UniRef50_Q814Z6 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=1;
           Bacillus cereus ATCC 14579|Rep: UDP-N-acetylglucosamine
           4-epimerase - Bacillus cereus (strain ATCC 14579 / DSM
           31)
          Length = 301

 Score = 33.5 bits (73), Expect = 6.3
 Identities = 17/63 (26%), Positives = 31/63 (49%)
 Frame = +2

Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 463
           V+HLAA  G         +  F +N  +  N+  AC++ N+  +V   +   + D+T+ P
Sbjct: 64  VVHLAATRGS-----QGKISEFHDNEILTQNLYDACYENNISNIVYASTISAYSDETSLP 118

Query: 464 IDE 472
            +E
Sbjct: 119 WNE 121


>UniRef50_Q7VRZ4 Cluster: Thymidine diphosphoglucose
           4,6-dehydratase; n=2; Bordetella|Rep: Thymidine
           diphosphoglucose 4,6-dehydratase - Bordetella pertussis
          Length = 326

 Score = 33.5 bits (73), Expect = 6.3
 Identities = 19/73 (26%), Positives = 34/73 (46%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GD+R     +A   +H    V+H AA+  GL        D F  N+     +++A  ++ 
Sbjct: 55  GDVRRGADLDAALREHAVDRVVHGAAVTAGLEREKNAAADIFTVNLLGAVKVMEAGLRHG 114

Query: 404 VKKVVSCLSTCIF 442
           V++VV   +  +F
Sbjct: 115 VRQVVQLGTGSVF 127


>UniRef50_Q1MP11 Cluster: Nucleoside-diphosphate-sugar epimerases;
           n=1; Lawsonia intracellularis PHE/MN1-00|Rep:
           Nucleoside-diphosphate-sugar epimerases - Lawsonia
           intracellularis (strain PHE/MN1-00)
          Length = 339

 Score = 33.5 bits (73), Expect = 6.3
 Identities = 19/69 (27%), Positives = 35/69 (50%)
 Frame = +2

Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406
           ++ D +  E LF+K+    VIH A     +  ++   L++++ N +    IL+ C KYN 
Sbjct: 59  NVEDTSMMEVLFSKYTFDAVIHFAG-YKSIAESLKIPLEYYQNNYNSTLTILRLCLKYNS 117

Query: 407 KKVVSCLST 433
             + S  +T
Sbjct: 118 TFIFSSSAT 126


>UniRef50_A5N5N5 Cluster: Predicted nucleoside-diphosphate-sugar
           epimerase; n=1; Clostridium kluyveri DSM 555|Rep:
           Predicted nucleoside-diphosphate-sugar epimerase -
           Clostridium kluyveri DSM 555
          Length = 336

 Score = 33.5 bits (73), Expect = 6.3
 Identities = 38/137 (27%), Positives = 57/137 (41%), Gaps = 4/137 (2%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPT--HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 397
           GD+ D    +  F   + T  +VIH A++V     N   N      N+    NI+  C +
Sbjct: 53  GDVTDTESLQKFFTVSESTDIYVIHCASIVT---LNPNPNGKVHAVNVGGTQNIIDKCVE 109

Query: 398 YNVKKVVSCLSTCIFPD-KTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574
           + VKK+V   ST   P+     PI E + H G      + YS  K     L       Y 
Sbjct: 110 HQVKKLVYISSTGAIPELPGNMPIKE-VTHFGIEGLVGY-YSVTKAEASQLVIDALAKYP 167

Query: 575 CMFTSVI-PCNVFGPHD 622
            +  S++ P  + GP+D
Sbjct: 168 QLDASLVHPSGICGPND 184


>UniRef50_A3ZSY0 Cluster: CDP glucose 4,6-dehydratase; n=1;
           Blastopirellula marina DSM 3645|Rep: CDP glucose
           4,6-dehydratase - Blastopirellula marina DSM 3645
          Length = 368

 Score = 33.5 bits (73), Expect = 6.3
 Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 3/119 (2%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAM-VGGLFHNMAHNLDFFRENMSINDNILQACHKY 400
           GD+RD ++ + +F    P  V+HLAA  +  L + +   L+ F  N+    N+L+AC   
Sbjct: 67  GDIRDLSKLKQVFQDFDPEIVLHLAAQPLVRLSYEIP--LETFDVNVLGTANVLEACRGL 124

Query: 401 NVKKVVSCLST--CIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESY 571
              +    ++T  C    +  +   ET      P      YS +K   +++   Y +SY
Sbjct: 125 QSLQAAVMVTTDKCYENREWDWSYRET-----DPLGGKDPYSASKACAEIVTSSYRDSY 178


>UniRef50_Q9HSU9 Cluster: GDP-D-mannose dehydratase; n=2;
           Halobacterium salinarum|Rep: GDP-D-mannose dehydratase -
           Halobacterium salinarium (Halobacterium halobium)
          Length = 309

 Score = 33.5 bits (73), Expect = 6.3
 Identities = 30/115 (26%), Positives = 49/115 (42%)
 Frame = +2

Query: 377 ILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRG 556
           ++ A  + +V  VV   S  I+    T+P  E+M     P S    Y+ +K   + L   
Sbjct: 104 VIDAAREADVDTVVVASSAAIYGSTETFPKVESMTEQ--PESP---YALSKHYTEKLALQ 158

Query: 557 YNESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGE 721
            +E Y     ++   N++GP  + +   + VIP  I  M D  +   P    DGE
Sbjct: 159 ASELYDIDTAALRYFNIYGPRQDPNGDYAAVIPKFISLMLDGER---PVIYGDGE 210


>UniRef50_A4FIG8 Cluster: Modular polyketide synthase; n=1;
           Saccharopolyspora erythraea NRRL 2338|Rep: Modular
           polyketide synthase - Saccharopolyspora erythraea
           (strain NRRL 23338)
          Length = 571

 Score = 33.1 bits (72), Expect = 8.4
 Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
 Frame = +2

Query: 599 CNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTF-XSDGEAXNH 733
           C  F P  +  ++   V+  +I+R+DDA+  GDP      G A NH
Sbjct: 224 CRPFSPDADGYVRGEGVLCFVIKRLDDALDSGDPVLAVIRGAAANH 269


>UniRef50_Q2U1I6 Cluster: Polyketide synthase modules and related
           proteins; n=1; Aspergillus oryzae|Rep: Polyketide
           synthase modules and related proteins - Aspergillus
           oryzae
          Length = 2407

 Score = 33.1 bits (72), Expect = 8.4
 Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 1/47 (2%)
 Frame = +2

Query: 599 CNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDP-TFXSDGEAXNHS 736
           C+ F    +  +K+  +   +++R+DDA+Q GDP      G A NHS
Sbjct: 236 CHTFDAKADGYIKAEGINAVILKRLDDAIQDGDPIRAVIRGTANNHS 282


>UniRef50_A5DWB0 Cluster: Putative uncharacterized protein; n=2;
           Saccharomycetales|Rep: Putative uncharacterized protein
           - Lodderomyces elongisporus (Yeast) (Saccharomyces
           elongisporus)
          Length = 328

 Score = 33.1 bits (72), Expect = 8.4
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = +2

Query: 515 YSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPH 619
           YS +K + D+L + Y +S+    T + P NVFGP+
Sbjct: 157 YSASKALADLLIQAYKQSFQLPITIIRPNNVFGPN 191


>UniRef50_A2R6J0 Cluster: Catalytic activity: dTDPglucose =
           dTDP-4-dehydro-6-deoxy-D-glucose + H2O; n=1; Aspergillus
           niger|Rep: Catalytic activity: dTDPglucose =
           dTDP-4-dehydro-6-deoxy-D-glucose + H2O - Aspergillus
           niger
          Length = 362

 Score = 33.1 bits (72), Expect = 8.4
 Identities = 32/131 (24%), Positives = 53/131 (40%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GDL D+ +  ALF + K   V+H AA    +  ++ + L F R N++    +L+A  +  
Sbjct: 81  GDLCDRDRVTALFQQFKVDAVVHFAAN-SHVDQSLVNPLSFTRSNVTGTHVLLEAARQAG 139

Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583
                  +ST           D         + +N  YS +K   +++   Y  S+    
Sbjct: 140 TVIRFIHISTDEVYGGNMPGQDYAFTEEDQLNPTN-PYSASKAAAEMIANSYRYSFHMPI 198

Query: 584 TSVIPCNVFGP 616
                 NVFGP
Sbjct: 199 IITRCNNVFGP 209


>UniRef50_O95455 Cluster: dTDP-D-glucose 4,6-dehydratase; n=24;
           Eumetazoa|Rep: dTDP-D-glucose 4,6-dehydratase - Homo
           sapiens (Human)
          Length = 350

 Score = 33.1 bits (72), Expect = 8.4
 Identities = 30/132 (22%), Positives = 52/132 (39%)
 Frame = +2

Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403
           GD+ D    + LF   K   V+H AA    +  +     +F   N+     ++ A H+  
Sbjct: 75  GDICDSHFVKLLFETEKIDIVLHFAAQTH-VDLSFVRAFEFTYVNVYGTHVLVSAAHEAR 133

Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583
           V+K +   +  ++        DE+     P   +N  Y+ +K   +   + Y E Y    
Sbjct: 134 VEKFIYVSTDEVYGGSLDKEFDES----SPKQPTN-PYASSKAAAECFVQSYWEQYKFPV 188

Query: 584 TSVIPCNVFGPH 619
                 NV+GPH
Sbjct: 189 VITRSSNVYGPH 200


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 809,157,277
Number of Sequences: 1657284
Number of extensions: 16371747
Number of successful extensions: 35926
Number of sequences better than 10.0: 182
Number of HSP's better than 10.0 without gapping: 34609
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 35837
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 68731504465
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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