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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= brP-0015
         (700 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC031791-1|AAH31791.1|  346|Homo sapiens ER lipid raft associate...   204   3e-52
AL138921-3|CAH72398.1|  346|Homo sapiens ER lipid raft associate...   204   3e-52
AK222480-1|BAD96200.1|  346|Homo sapiens SPFH domain family, mem...   204   3e-52
AF064093-1|AAC26658.1|  346|Homo sapiens KE04p protein.               204   3e-52
AY358108-1|AAQ88475.1|  339|Homo sapiens C8orf2 protein.              203   4e-52
AB018790-1|BAA36845.1|  339|Homo sapiens protein ( Homo sapiens ...   203   4e-52
BC005950-1|AAH05950.1|  347|Homo sapiens ERLIN2 protein protein.      202   7e-52
BC067765-1|AAH67765.1|  206|Homo sapiens ERLIN2 protein protein.      185   2e-46
BC050611-1|AAH50611.1|  229|Homo sapiens ERLIN2 protein protein.      185   2e-46
BC048308-1|AAH48308.1|  152|Homo sapiens ER lipid raft associate...   185   2e-46
AY358851-1|AAQ89210.1|  152|Homo sapiens C8orf2 protein.              185   2e-46

>BC031791-1|AAH31791.1|  346|Homo sapiens ER lipid raft associated 1
           protein.
          Length = 346

 Score =  204 bits (497), Expect = 3e-52
 Identities = 99/197 (50%), Positives = 134/197 (68%)
 Frame = +2

Query: 107 MADQSSILAIVILAVGVTVHFSLHKVEEGHVGVYYRGGALLPVTSQAGFHMMIPLLTSYK 286
           M     ++A V+  V V ++ S+HK+EEGH+ VYYRGGALL   S  G+H+M+P +T+++
Sbjct: 1   MTQARVLVAAVVGLVAVLLYASIHKIEEGHLAVYYRGGALLTSPSGPGYHIMLPFITTFR 60

Query: 287 AIQTTLQTDEVKNVPCGTSGGVLIYFERIEVVNKQDPQSVLXMVRNFTXEYDRTXIFNKV 466
           ++QTTLQTDEVKNVPCGTSGGV+IY +RIEVVN   P +V  +VRN+T +YD+T IFNK+
Sbjct: 61  SVQTTLQTDEVKNVPCGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFNKI 120

Query: 467 HHELNQXCSAHTHARGIHXFV*SNXREFTDQXXKRILMKWLQGLRVEAVXVAKPXIXTXN 646
           HHELNQ CSAHT  + ++  +     E   Q  ++ L     GL ++AV V KP I    
Sbjct: 121 HHELNQFCSAHT-LQEVYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEAI 179

Query: 647 XENXELMGXXQSKLLIA 697
             N ELM   ++KLLIA
Sbjct: 180 RRNFELMEAEKTKLLIA 196


>AL138921-3|CAH72398.1|  346|Homo sapiens ER lipid raft associated 1
           protein.
          Length = 346

 Score =  204 bits (497), Expect = 3e-52
 Identities = 99/197 (50%), Positives = 134/197 (68%)
 Frame = +2

Query: 107 MADQSSILAIVILAVGVTVHFSLHKVEEGHVGVYYRGGALLPVTSQAGFHMMIPLLTSYK 286
           M     ++A V+  V V ++ S+HK+EEGH+ VYYRGGALL   S  G+H+M+P +T+++
Sbjct: 1   MTQARVLVAAVVGLVAVLLYASIHKIEEGHLAVYYRGGALLTSPSGPGYHIMLPFITTFR 60

Query: 287 AIQTTLQTDEVKNVPCGTSGGVLIYFERIEVVNKQDPQSVLXMVRNFTXEYDRTXIFNKV 466
           ++QTTLQTDEVKNVPCGTSGGV+IY +RIEVVN   P +V  +VRN+T +YD+T IFNK+
Sbjct: 61  SVQTTLQTDEVKNVPCGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFNKI 120

Query: 467 HHELNQXCSAHTHARGIHXFV*SNXREFTDQXXKRILMKWLQGLRVEAVXVAKPXIXTXN 646
           HHELNQ CSAHT  + ++  +     E   Q  ++ L     GL ++AV V KP I    
Sbjct: 121 HHELNQFCSAHT-LQEVYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEAI 179

Query: 647 XENXELMGXXQSKLLIA 697
             N ELM   ++KLLIA
Sbjct: 180 RRNFELMEAEKTKLLIA 196


>AK222480-1|BAD96200.1|  346|Homo sapiens SPFH domain family, member
           1 variant protein.
          Length = 346

 Score =  204 bits (497), Expect = 3e-52
 Identities = 99/197 (50%), Positives = 134/197 (68%)
 Frame = +2

Query: 107 MADQSSILAIVILAVGVTVHFSLHKVEEGHVGVYYRGGALLPVTSQAGFHMMIPLLTSYK 286
           M     ++A V+  V V ++ S+HK+EEGH+ VYYRGGALL   S  G+H+M+P +T+++
Sbjct: 1   MTQARVLVAAVVGLVAVLLYASIHKIEEGHLAVYYRGGALLTSPSGPGYHIMLPFITTFR 60

Query: 287 AIQTTLQTDEVKNVPCGTSGGVLIYFERIEVVNKQDPQSVLXMVRNFTXEYDRTXIFNKV 466
           ++QTTLQTDEVKNVPCGTSGGV+IY +RIEVVN   P +V  +VRN+T +YD+T IFNK+
Sbjct: 61  SVQTTLQTDEVKNVPCGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFNKI 120

Query: 467 HHELNQXCSAHTHARGIHXFV*SNXREFTDQXXKRILMKWLQGLRVEAVXVAKPXIXTXN 646
           HHELNQ CSAHT  + ++  +     E   Q  ++ L     GL ++AV V KP I    
Sbjct: 121 HHELNQFCSAHT-LQEVYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEAI 179

Query: 647 XENXELMGXXQSKLLIA 697
             N ELM   ++KLLIA
Sbjct: 180 RRNFELMEAEKTKLLIA 196


>AF064093-1|AAC26658.1|  346|Homo sapiens KE04p protein.
          Length = 346

 Score =  204 bits (497), Expect = 3e-52
 Identities = 99/197 (50%), Positives = 134/197 (68%)
 Frame = +2

Query: 107 MADQSSILAIVILAVGVTVHFSLHKVEEGHVGVYYRGGALLPVTSQAGFHMMIPLLTSYK 286
           M     ++A V+  V V ++ S+HK+EEGH+ VYYRGGALL   S  G+H+M+P +T+++
Sbjct: 1   MTQARVLVAAVVGLVAVLLYASIHKIEEGHLAVYYRGGALLTSPSGPGYHIMLPFITTFR 60

Query: 287 AIQTTLQTDEVKNVPCGTSGGVLIYFERIEVVNKQDPQSVLXMVRNFTXEYDRTXIFNKV 466
           ++QTTLQTDEVKNVPCGTSGGV+IY +RIEVVN   P +V  +VRN+T +YD+T IFNK+
Sbjct: 61  SVQTTLQTDEVKNVPCGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFNKI 120

Query: 467 HHELNQXCSAHTHARGIHXFV*SNXREFTDQXXKRILMKWLQGLRVEAVXVAKPXIXTXN 646
           HHELNQ CSAHT  + ++  +     E   Q  ++ L     GL ++AV V KP I    
Sbjct: 121 HHELNQFCSAHT-LQEVYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEAI 179

Query: 647 XENXELMGXXQSKLLIA 697
             N ELM   ++KLLIA
Sbjct: 180 RRNFELMEAEKTKLLIA 196


>AY358108-1|AAQ88475.1|  339|Homo sapiens C8orf2 protein.
          Length = 339

 Score =  203 bits (496), Expect = 4e-52
 Identities = 99/197 (50%), Positives = 133/197 (67%)
 Frame = +2

Query: 107 MADQSSILAIVILAVGVTVHFSLHKVEEGHVGVYYRGGALLPVTSQAGFHMMIPLLTSYK 286
           MA   +++A+       ++  ++HK+EEGH+GVYYRGGALL  TS  GFH+M+P +TSYK
Sbjct: 1   MAQLGAVVAVASSFFCASLFSAVHKIEEGHIGVYYRGGALLTSTSGPGFHLMLPFITSYK 60

Query: 287 AIQTTLQTDEVKNVPCGTSGGVLIYFERIEVVNKQDPQSVLXMVRNFTXEYDRTXIFNKV 466
           ++QTTLQTDEVKNVPCGTSGGV+IYF+RIEVVN   P +V  +V+N+T +YD+  IFNK+
Sbjct: 61  SVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPNAVYDIVKNYTADYDKALIFNKI 120

Query: 467 HHELNQXCSAHTHARGIHXFV*SNXREFTDQXXKRILMKWLQGLRVEAVXVAKPXIXTXN 646
           HHELNQ CS HT  + ++  +     E      ++ L     GL ++AV V KP I    
Sbjct: 121 HHELNQFCSVHT-LQEVYIELFDQIDENLKLALQQDLTSMAPGLVIQAVRVTKPNIPEAI 179

Query: 647 XENXELMGXXQSKLLIA 697
             N ELM   ++KLLIA
Sbjct: 180 RRNYELMESEKTKLLIA 196


>AB018790-1|BAA36845.1|  339|Homo sapiens protein ( Homo sapiens
           gene, complete cds, similar to Caenorhabditis elegans
           C42C1.9 gene sequence. ).
          Length = 339

 Score =  203 bits (496), Expect = 4e-52
 Identities = 99/197 (50%), Positives = 133/197 (67%)
 Frame = +2

Query: 107 MADQSSILAIVILAVGVTVHFSLHKVEEGHVGVYYRGGALLPVTSQAGFHMMIPLLTSYK 286
           MA   +++A+       ++  ++HK+EEGH+GVYYRGGALL  TS  GFH+M+P +TSYK
Sbjct: 1   MAQLGAVVAVASSFFCASLFSAVHKIEEGHIGVYYRGGALLTSTSGPGFHLMLPFITSYK 60

Query: 287 AIQTTLQTDEVKNVPCGTSGGVLIYFERIEVVNKQDPQSVLXMVRNFTXEYDRTXIFNKV 466
           ++QTTLQTDEVKNVPCGTSGGV+IYF+RIEVVN   P +V  +V+N+T +YD+  IFNK+
Sbjct: 61  SVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPNAVYDIVKNYTADYDKALIFNKI 120

Query: 467 HHELNQXCSAHTHARGIHXFV*SNXREFTDQXXKRILMKWLQGLRVEAVXVAKPXIXTXN 646
           HHELNQ CS HT  + ++  +     E      ++ L     GL ++AV V KP I    
Sbjct: 121 HHELNQFCSVHT-LQEVYIELFDQIDENLKLALQQDLTSMAPGLVIQAVRVTKPNIPEAI 179

Query: 647 XENXELMGXXQSKLLIA 697
             N ELM   ++KLLIA
Sbjct: 180 RRNYELMESEKTKLLIA 196


>BC005950-1|AAH05950.1|  347|Homo sapiens ERLIN2 protein protein.
          Length = 347

 Score =  202 bits (494), Expect = 7e-52
 Identities = 99/197 (50%), Positives = 132/197 (67%)
 Frame = +2

Query: 107 MADQSSILAIVILAVGVTVHFSLHKVEEGHVGVYYRGGALLPVTSQAGFHMMIPLLTSYK 286
           MA   +++A+       ++  ++HK+EEGH+GVYYRGGALL  TS  GFH+M+P +TSYK
Sbjct: 1   MAQLGAVVAVASSFFCASLFSAVHKIEEGHIGVYYRGGALLTSTSGPGFHLMLPFITSYK 60

Query: 287 AIQTTLQTDEVKNVPCGTSGGVLIYFERIEVVNKQDPQSVLXMVRNFTXEYDRTXIFNKV 466
            +QTTLQTDEVKNVPCGTSGGV+IYF+RIEVVN   P +V  +V+N+T +YD+  IFNK+
Sbjct: 61  PVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPNAVYDIVKNYTADYDKALIFNKI 120

Query: 467 HHELNQXCSAHTHARGIHXFV*SNXREFTDQXXKRILMKWLQGLRVEAVXVAKPXIXTXN 646
           HHELNQ CS HT  + ++  +     E      ++ L     GL ++AV V KP I    
Sbjct: 121 HHELNQFCSVHT-LQEVYIELFDQIDENLKLALQQDLTSMAPGLVIQAVRVTKPNIPEAI 179

Query: 647 XENXELMGXXQSKLLIA 697
             N ELM   ++KLLIA
Sbjct: 180 RRNYELMESEKTKLLIA 196


>BC067765-1|AAH67765.1|  206|Homo sapiens ERLIN2 protein protein.
          Length = 206

 Score =  185 bits (450), Expect = 2e-46
 Identities = 80/132 (60%), Positives = 104/132 (78%)
 Frame = +2

Query: 107 MADQSSILAIVILAVGVTVHFSLHKVEEGHVGVYYRGGALLPVTSQAGFHMMIPLLTSYK 286
           MA   +++A+       ++  ++HK+EEGH+GVYYRGGALL  TS  GFH+M+P +TSYK
Sbjct: 1   MAQLGAVVAVASSFFCASLFSAVHKIEEGHIGVYYRGGALLTSTSGPGFHLMLPFITSYK 60

Query: 287 AIQTTLQTDEVKNVPCGTSGGVLIYFERIEVVNKQDPQSVLXMVRNFTXEYDRTXIFNKV 466
           ++QTTLQTDEVKNVPCGTSGGV+IYF+RIEVVN   P +V  +V+N+T +YD+  IFNK+
Sbjct: 61  SVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPNAVYDIVKNYTADYDKALIFNKI 120

Query: 467 HHELNQXCSAHT 502
           HHELNQ CS HT
Sbjct: 121 HHELNQFCSVHT 132


>BC050611-1|AAH50611.1|  229|Homo sapiens ERLIN2 protein protein.
          Length = 229

 Score =  185 bits (450), Expect = 2e-46
 Identities = 80/132 (60%), Positives = 104/132 (78%)
 Frame = +2

Query: 107 MADQSSILAIVILAVGVTVHFSLHKVEEGHVGVYYRGGALLPVTSQAGFHMMIPLLTSYK 286
           MA   +++A+       ++  ++HK+EEGH+GVYYRGGALL  TS  GFH+M+P +TSYK
Sbjct: 24  MAQLGAVVAVASSFFCASLFSAVHKIEEGHIGVYYRGGALLTSTSGPGFHLMLPFITSYK 83

Query: 287 AIQTTLQTDEVKNVPCGTSGGVLIYFERIEVVNKQDPQSVLXMVRNFTXEYDRTXIFNKV 466
           ++QTTLQTDEVKNVPCGTSGGV+IYF+RIEVVN   P +V  +V+N+T +YD+  IFNK+
Sbjct: 84  SVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPNAVYDIVKNYTADYDKALIFNKI 143

Query: 467 HHELNQXCSAHT 502
           HHELNQ CS HT
Sbjct: 144 HHELNQFCSVHT 155


>BC048308-1|AAH48308.1|  152|Homo sapiens ER lipid raft associated 2
           protein.
          Length = 152

 Score =  185 bits (450), Expect = 2e-46
 Identities = 80/132 (60%), Positives = 104/132 (78%)
 Frame = +2

Query: 107 MADQSSILAIVILAVGVTVHFSLHKVEEGHVGVYYRGGALLPVTSQAGFHMMIPLLTSYK 286
           MA   +++A+       ++  ++HK+EEGH+GVYYRGGALL  TS  GFH+M+P +TSYK
Sbjct: 1   MAQLGAVVAVASSFFCASLFSAVHKIEEGHIGVYYRGGALLTSTSGPGFHLMLPFITSYK 60

Query: 287 AIQTTLQTDEVKNVPCGTSGGVLIYFERIEVVNKQDPQSVLXMVRNFTXEYDRTXIFNKV 466
           ++QTTLQTDEVKNVPCGTSGGV+IYF+RIEVVN   P +V  +V+N+T +YD+  IFNK+
Sbjct: 61  SVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPNAVYDIVKNYTADYDKALIFNKI 120

Query: 467 HHELNQXCSAHT 502
           HHELNQ CS HT
Sbjct: 121 HHELNQFCSVHT 132


>AY358851-1|AAQ89210.1|  152|Homo sapiens C8orf2 protein.
          Length = 152

 Score =  185 bits (450), Expect = 2e-46
 Identities = 80/132 (60%), Positives = 104/132 (78%)
 Frame = +2

Query: 107 MADQSSILAIVILAVGVTVHFSLHKVEEGHVGVYYRGGALLPVTSQAGFHMMIPLLTSYK 286
           MA   +++A+       ++  ++HK+EEGH+GVYYRGGALL  TS  GFH+M+P +TSYK
Sbjct: 1   MAQLGAVVAVASSFFCASLFSAVHKIEEGHIGVYYRGGALLTSTSGPGFHLMLPFITSYK 60

Query: 287 AIQTTLQTDEVKNVPCGTSGGVLIYFERIEVVNKQDPQSVLXMVRNFTXEYDRTXIFNKV 466
           ++QTTLQTDEVKNVPCGTSGGV+IYF+RIEVVN   P +V  +V+N+T +YD+  IFNK+
Sbjct: 61  SVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPNAVYDIVKNYTADYDKALIFNKI 120

Query: 467 HHELNQXCSAHT 502
           HHELNQ CS HT
Sbjct: 121 HHELNQFCSVHT 132


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 89,263,407
Number of Sequences: 237096
Number of extensions: 1831353
Number of successful extensions: 6087
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 5983
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6073
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8063224416
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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