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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Nnor0036
         (682 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

CR536548-1|CAG38785.1|  338|Homo sapiens MDH2 protein.                230   3e-60
BC001917-1|AAH01917.1|  338|Homo sapiens malate dehydrogenase 2,...   229   5e-60
AF047470-1|AAC03787.1|  338|Homo sapiens malate dehydrogenase pr...   229   5e-60
DQ402957-1|ABD77290.1|  305|Homo sapiens mitochondrial malate de...   219   7e-57
AC005077-1|AAS07425.1|  316|Homo sapiens unknown protein.             217   3e-56
BC014340-1|AAH14340.1|  234|Homo sapiens LDHAL6A protein protein.      55   3e-07
AY581313-1|AAS93432.1|  332|Homo sapiens lactate dehydrogenase p...    55   3e-07
AK131523-1|BAD18662.1|  332|Homo sapiens protein ( Homo sapiens ...    55   3e-07
BC008735-1|AAH08735.2|  627|Homo sapiens FBXL10 protein protein.       33   1.2  
AK027692-1|BAB55301.1|  653|Homo sapiens protein ( Homo sapiens ...    33   1.2  
AK027440-1|BAB55112.1|  704|Homo sapiens protein ( Homo sapiens ...    33   1.2  
AJ459424-1|CAD30700.1| 1336|Homo sapiens JEMMA protein protein.        33   1.2  
AB031230-1|BAA97672.1|  827|Homo sapiens protein containing CXXC...    33   1.2  
M55172-1|AAA62824.1| 2316|Homo sapiens large aggregating cartila...    31   5.0  

>CR536548-1|CAG38785.1|  338|Homo sapiens MDH2 protein.
          Length = 338

 Score =  230 bits (563), Expect = 3e-60
 Identities = 112/192 (58%), Positives = 144/192 (75%)
 Frame = +2

Query: 71  MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 250
           M S  ++P + A++   ++FST++Q N K         IGQPL+LLLK +PLV+RL LYD
Sbjct: 1   MLSALVRPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57

Query: 251 IAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNT 430
           IA  TPGVAADLSH+ T A V G+ GPE+L   +K  DVVVIPAGVPRKPGMTRDDLFNT
Sbjct: 58  IAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT 116

Query: 431 NASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVR 610
           NA+IV  +  + AQ+ P+A++ +I NPVNST+PI +EV KK GVY+PN++ GVTTLD+VR
Sbjct: 117 NATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVR 176

Query: 611 AATFVGEINGVD 646
           A TFV E+ G+D
Sbjct: 177 ANTFVAELKGLD 188


>BC001917-1|AAH01917.1|  338|Homo sapiens malate dehydrogenase 2,
           NAD (mitochondrial) protein.
          Length = 338

 Score =  229 bits (561), Expect = 5e-60
 Identities = 112/192 (58%), Positives = 143/192 (74%)
 Frame = +2

Query: 71  MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 250
           M S   +P + A++   ++FST++Q N K         IGQPL+LLLK +PLV+RL LYD
Sbjct: 1   MLSALARPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57

Query: 251 IAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNT 430
           IA  TPGVAADLSH+ T A V G+ GPE+L   +K  DVVVIPAGVPRKPGMTRDDLFNT
Sbjct: 58  IAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT 116

Query: 431 NASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVR 610
           NA+IV  +  + AQ+ P+A++ +I NPVNST+PI +EV KK GVY+PN++ GVTTLD+VR
Sbjct: 117 NATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVR 176

Query: 611 AATFVGEINGVD 646
           A TFV E+ G+D
Sbjct: 177 ANTFVAELKGLD 188


>AF047470-1|AAC03787.1|  338|Homo sapiens malate dehydrogenase
           precursor protein.
          Length = 338

 Score =  229 bits (561), Expect = 5e-60
 Identities = 112/192 (58%), Positives = 143/192 (74%)
 Frame = +2

Query: 71  MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 250
           M S   +P + A++   ++FST++Q N K         IGQPL+LLLK +PLV+RL LYD
Sbjct: 1   MLSALARPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57

Query: 251 IAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNT 430
           IA  TPGVAADLSH+ T A V G+ GPE+L   +K  DVVVIPAGVPRKPGMTRDDLFNT
Sbjct: 58  IAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT 116

Query: 431 NASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVR 610
           NA+IV  +  + AQ+ P+A++ +I NPVNST+PI +EV KK GVY+PN++ GVTTLD+VR
Sbjct: 117 NATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVR 176

Query: 611 AATFVGEINGVD 646
           A TFV E+ G+D
Sbjct: 177 ANTFVAELKGLD 188


>DQ402957-1|ABD77290.1|  305|Homo sapiens mitochondrial malate
           dehydrogenase 2, NAD protein.
          Length = 305

 Score =  219 bits (535), Expect = 7e-57
 Identities = 105/168 (62%), Positives = 128/168 (76%)
 Frame = +2

Query: 143 QRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGH 322
           Q N K         IGQPL+LLLK +PLV+RL LYDIA  TPGVAADLSH+ T A V G+
Sbjct: 1   QNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH-TPGVAADLSHIETKAAVKGY 59

Query: 323 KGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAII 502
            GPE+L   +K  DVVVIPAGVPRKPGMTRDDLFNTNA+IV  +  + AQ+ P+A++ +I
Sbjct: 60  LGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVI 119

Query: 503 TNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVD 646
            NPVNST+PI +EV KK GVY+PN++ GVTTLD+VRA TFV E+ G+D
Sbjct: 120 ANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLD 167


>AC005077-1|AAS07425.1|  316|Homo sapiens unknown protein.
          Length = 316

 Score =  217 bits (530), Expect = 3e-56
 Identities = 102/154 (66%), Positives = 125/154 (81%)
 Frame = +2

Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDAD 364
           IGQPL+LLLK +PLV+RL LYDIA  TPGVAADLSH+ T A V G+ GPE+L   +K  D
Sbjct: 14  IGQPLSLLLKNSPLVSRLTLYDIAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCD 72

Query: 365 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEV 544
           VVVIPAGVPRKPGMTRDDLFNTNA+IV  +  + AQ+ P+A++ +I NPVNST+PI +EV
Sbjct: 73  VVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEV 132

Query: 545 LKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVD 646
            KK GVY+PN++ GVTTLD+VRA TFV E+ G+D
Sbjct: 133 FKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLD 166


>BC014340-1|AAH14340.1|  234|Homo sapiens LDHAL6A protein protein.
          Length = 234

 Score = 54.8 bits (126), Expect = 3e-07
 Identities = 48/176 (27%), Positives = 77/176 (43%), Gaps = 2/176 (1%)
 Frame = +2

Query: 122 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHMN 298
           KNF+     +           +G   A+ +    L   L L D+      G   DL H +
Sbjct: 10  KNFAEEEAIHHNKISIVGTGSVGVACAISILLKGLSDELVLVDVDEGKLKGETMDLQHGS 69

Query: 299 TPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 478
              K+      ++      ++++V+I AG  +K G TR DL   N SI + +  +I Q +
Sbjct: 70  PFMKMPNIVSSKDYLVTA-NSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYS 128

Query: 479 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGV 643
           P   + I+TNPV+    I + V  K   +  NRV+G    LD  R   F+G+  G+
Sbjct: 129 PHCKLLIVTNPVD----ILTYVAWKLSGFPKNRVIGSGCNLDSARFRYFIGQRLGI 180


>AY581313-1|AAS93432.1|  332|Homo sapiens lactate dehydrogenase
           protein.
          Length = 332

 Score = 54.8 bits (126), Expect = 3e-07
 Identities = 48/176 (27%), Positives = 77/176 (43%), Gaps = 2/176 (1%)
 Frame = +2

Query: 122 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHMN 298
           KNF+     +           +G   A+ +    L   L L D+      G   DL H +
Sbjct: 10  KNFAEEEAIHHNKISIVGTGSVGVACAISILLKGLSDELVLVDVDEGKLKGETMDLQHGS 69

Query: 299 TPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 478
              K+      ++      ++++V+I AG  +K G TR DL   N SI + +  +I Q +
Sbjct: 70  PFMKMPNIVSSKDYLVTA-NSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYS 128

Query: 479 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGV 643
           P   + I+TNPV+    I + V  K   +  NRV+G    LD  R   F+G+  G+
Sbjct: 129 PHCKLLIVTNPVD----ILTYVAWKLSGFPKNRVIGSGCNLDSARFRYFIGQRLGI 180


>AK131523-1|BAD18662.1|  332|Homo sapiens protein ( Homo sapiens
           cDNA FLJ43406 fis, clone OCBBF2019823, highly  similar
           to Homo sapiens lactate dehydrogenase A -like (LDHL). ).
          Length = 332

 Score = 54.8 bits (126), Expect = 3e-07
 Identities = 48/176 (27%), Positives = 77/176 (43%), Gaps = 2/176 (1%)
 Frame = +2

Query: 122 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHMN 298
           KNF+     +           +G   A+ +    L   L L D+      G   DL H +
Sbjct: 10  KNFAEEEAIHHNKISIVGTGSVGVACAISILLKGLSDELVLVDVDEGKLKGETMDLQHGS 69

Query: 299 TPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 478
              K+      ++      ++++V+I AG  +K G TR DL   N SI + +  +I Q +
Sbjct: 70  PFMKMPNIVSSKDYLVTA-NSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYS 128

Query: 479 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGV 643
           P   + I+TNPV+    I + V  K   +  NRV+G    LD  R   F+G+  G+
Sbjct: 129 PHCKLLIVTNPVD----ILTYVAWKLSGFPKNRVIGSGCNLDSARFRYFIGQRLGI 180


>BC008735-1|AAH08735.2|  627|Homo sapiens FBXL10 protein protein.
          Length = 627

 Score = 32.7 bits (71), Expect = 1.2
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -3

Query: 167 RPPL*SSSVMWWKSSLHHFVQQ 102
           RPPL SS   WW+SSL +F QQ
Sbjct: 125 RPPLGSSLSPWWRSSLTYFQQQ 146


>AK027692-1|BAB55301.1|  653|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14786 fis, clone NT2RP4000737, moderately
           similar to Mus musculus F-box protein FBL10 mRNA. ).
          Length = 653

 Score = 32.7 bits (71), Expect = 1.2
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -3

Query: 167 RPPL*SSSVMWWKSSLHHFVQQ 102
           RPPL SS   WW+SSL +F QQ
Sbjct: 151 RPPLGSSLSPWWRSSLTYFQQQ 172


>AK027440-1|BAB55112.1|  704|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14534 fis, clone NT2RM2000599, weakly similar to
           Homo sapiens F-box protein Lilina (LILINA) mRNA. ).
          Length = 704

 Score = 32.7 bits (71), Expect = 1.2
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -3

Query: 167 RPPL*SSSVMWWKSSLHHFVQQ 102
           RPPL SS   WW+SSL +F QQ
Sbjct: 202 RPPLGSSLSPWWRSSLTYFQQQ 223


>AJ459424-1|CAD30700.1| 1336|Homo sapiens JEMMA protein protein.
          Length = 1336

 Score = 32.7 bits (71), Expect = 1.2
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -3

Query: 167 RPPL*SSSVMWWKSSLHHFVQQ 102
           RPPL SS   WW+SSL +F QQ
Sbjct: 834 RPPLGSSLSPWWRSSLTYFQQQ 855


>AB031230-1|BAA97672.1|  827|Homo sapiens protein containing CXXC
           domain 2 protein.
          Length = 827

 Score = 32.7 bits (71), Expect = 1.2
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -3

Query: 167 RPPL*SSSVMWWKSSLHHFVQQ 102
           RPPL SS   WW+SSL +F QQ
Sbjct: 358 RPPLGSSLSPWWRSSLTYFQQQ 379


>M55172-1|AAA62824.1| 2316|Homo sapiens large aggregating cartilage
           proteoglycan core protein protein.
          Length = 2316

 Score = 30.7 bits (66), Expect = 5.0
 Identities = 14/44 (31%), Positives = 20/44 (45%)
 Frame = +1

Query: 190 PAFGPSTEAESSGDQAGFIRHSACDPRRRSRPFPHEHPSQGQRP 321
           P  G  TE  + G  A  +  ++ +P     PFP E PS  + P
Sbjct: 761 PPTGAETEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEP 804


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 109,974,760
Number of Sequences: 237096
Number of extensions: 2696005
Number of successful extensions: 7042
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 6499
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7028
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7727256732
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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